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      • KCI등재

        좌골신경통에 대한 전침 치료: 체계적 문헌고찰 및 메타분석

        김예은 ( Ye-eun Kim ),안정훈 ( Jeong-hoon Ahn ),차윤엽 ( Yun-yeop Cha ),한인식 ( In-sik Han ),허인 ( In Heo ),박인화 ( In-hwa Park ) 한방재활의학과학회 2022 한방재활의학과학회지 Vol.32 No.2

        Objectives This study was conducted to evaluate the effect of electro-acupuncture for sciatica. Methods We searched 13 online databases (Kmbase, Research Information Sharing Service [RISS], National Digital Science Library [NDSL], Oriental Medicine Advanced Searching Integrated System [OASIS], Koreanstudies, Koreantk, DBpia, PubMed, Cochrane, EMBASE, Medline, China National Knowledge Infrastructure [CNKI], Jstage) to find randomized-controlled clinical trials (RCTs) that used electro-acupuncture for sciatica. Efficacy rate and visual analogue scale (VAS) were mainly analyzed as a main evaluation criteria. Results Among 583 articles that were searched, 24 RCTs were finally selected and 18 RCTs were statistically analyzed. Electro-acupuncture was more effective than acupuncture in terms of efficacy rate (p<0.00001) and VAS (p<0.00001). Also, Electroacupuncture was more effective than western medication in terms of efficacy rate (p= 0.0005). However, the effectiveness of electro-acupuncture was not identified compared to physical therapy (p=0.42). Electro-acupuncture significantly improved efficacy rate when combined with physical therapy than physical therapy alone (p<0.0001). In addition, electro-acupuncture plus Chuna manual therapy compared to Chuna manual therapy alone showed positive results for efficacy rate (p=0.05) and VAS (p <0.0001). Conclusions Based on results, the effectiveness of electro-acupuncture for sciatica was identified. However, this study has limitations because the RCTs included in this study were small in number and published in a particular region. Although this study could be a groundwork for well designed research for sciatica. (J Korean Med Rehabil 2022;32(2):105-121)

      • KCI등재

        Oroxylin A와 관련 유도체 합성 및 효능에 관한 고찰

        김예은(Ye Eun Kim),이상협(Sang Hyup Lee) 대한약학회 2021 약학회지 Vol.65 No.6

        Oroxylin A is a flavonoid compound found in some medicinal plants. Oroxylin A is known to possess a variety of biological properties such as anti-cancer, anti-inflammatory, and neuroprotective effects. In particular, the anti-cancer effect via apoptosis induction and neuroprotective effect through γ-aminobutyric acid type A (GABAA) receptor antagonism are remarkable. Based on this usefulness, extensive efforts to synthesize oroxylin A have been continued. However, semisyntheses using flavone compounds as starting materials rather than total syntheses were mainly conducted, owing to the difficulty of synthesizing oroxylin A. Regarding the semi-synthesis of oroxylinA, several methods using flavone compounds (baicalein, wogonin, or baicalin) were employed to give 8-62% product yields through 3-step reactions. Derivative syntheses were also performed while investigating their biological properties. Therefore, syntheses and biological evaluation of oroxylin A and its derivatives were reviewed to assess and enhance the potential of oroxylin A as a medicinal component.

      • 포쉐(Poche)의 다의성을 통해서 본 벽의 단면과 대지의 관계성에 관한 연구

        김예은(Kim, Ye-Eun),구영민(Koo, Young-Min) 대한건축학회 2020 대한건축학회 학술발표대회 논문집 Vol.40 No.2

        Poche, which can be defined and applied in architecture, means including wall and other solids in the building, which means that the construction and decoration are reproduced simultaneously. Since modern times, the concept of space has become multi-directional and de-structural as the walls have become free from the role of structure, and Poche, which was considered a structural volume inside the walls, has become capable of various interpretations along with changes in the perception of the walls. The purpose of this study is to analyze the architectural applicability of Poche as a medium of land and architecture in the context of modern indeterminate cities after a comparative analysis of how Poche"s Polysemous Notion enables the transition perception of ‘the Section of a Wall’ and ‘relationship with Earth’ in architectural spaces.

      • KCI등재

        경추성 현훈에 대한 전침 치료: 체계적 문헌고찰 및 메타분석

        김예은 ( Ye-eun Kim ),정인채 ( In-che Chung ),차윤엽 ( Yun-yeop Cha ),한인식 ( In-sik Han ),박인화 ( In-hwa Park ) 한방재활의학과학회 2021 한방재활의학과학회지 Vol.31 No.1

        Objectives The objective of this study was to appraise the effect of electro-acupuncture (EA) for the treatment of cervical vertigo. Methods We performed a literature search using nine electronic databases up to the end of November 2020. We included randomized controlled trials (RCTs) which appraised the effect of EA in the treatment of cervical vertigo. The risk of bias was evaluated from the Cochrane risk of bias tool. Results Thirteen appropriate RCTs were included and analyzed. The efficacy rate of the EA group was statistically higher compared with the control group treated with western medicine (p<0.00001). EA treatment significantly improved efficacy rate when combined with western medicine than western medicine alone (p<0.0001). Also EA used with combined therapy (traction, traditional chinese medicine, injection) significantly improved efficacy rate compared with combined therapy alone (p=0.02). Meta-analysis of thirteen studies demonstrated positive results for using EA for the treatment of cervical vertigo. Conclusions Based on results, EA treatment could be effective in cervical vertigo. However, it should be noted that the studies included in this research are regionally biased and small in number. Further well-designed research should be required. (J Korean Med Rehabil 2021;31(1):109-118)

      • KCI등재

        집게손발톱에서 탄산가스 프락셔널 레이저와 국소 도포제 병합 치료 연구

        김예은 ( Ye Eun Kim ),조의현 ( Ui Hyeon Jo ),박현선 ( Hyunsun Park ) 대한피부과학회 2019 대한피부과학회지 Vol.57 No.10

        Background: Pincer nail is a deformity of the nail that is characterized by the transverse overcurvature of the nail plate. Both conservative and surgical treatments can be used to treat pincer nail. However, there are no reports regarding non-surgical, laser treatment of pincer nail. Objective: To evaluate the treatment outcomes and adverse events of CO<sub>2</sub> fractional laser and topical agent combination therapy on pincer nail. Methods: Eleven pincer nails (all great toenails) were treated with a CO<sub>2</sub> fractional laser. An antifungal agent (in case of co-existing onychomycosis) or 20% urea cream was applied to the toenails. The effect of the treatment was measured by evaluating the difference in the width index, height index, and nail angle before and after treatment. Changes in pain levels were also evaluated. All adverse events and recurrences were observed until the last follow-up visit. Results: The mean number of laser treatments was 2.27 and the mean follow-up period was 18.36 weeks after the last treatment. All 3 measured indices changed significantly after the treatment. The width index increased by 0.16 (p=0.0016), the height index decreased by 1.89 (p=0.008), and the nail angle increased by 29.60° (p=0.005). The pain was reduced in all cases. There were no serious adverse events. Conclusion: The combination of CO<sub>2</sub> fractional laser therapy and topical application is an effective and tolerable treatment for pincer nail. Larger studies with long-term observations are needed to confirm this result. (Korean J Dermatol 2019;57(10):587∼593)

      • KCI등재

        독도의 자생식물의 근권에서 분리한 원핵 미생물의 다양성 분석

        김예은(Ye-Eun Kim),윤혁준(Hyeokjun Yoon),유영현(Young-Hyun You),현(Hyun Kim),서영교(Yeonggyo Seo),미애(Miae Kim),우주리(Ju-Ri Woo),남윤종(Yoon-Jong Nam),이리나(Khalmuratova Irina),이경민(Gyeong-Min Lee),송진하(Jin-Ha Song),진영주(Y 한국생명과학회 2014 생명과학회지 Vol.24 No.4

        본 연구에서는 독도에 자생하는 3종의 해안식물 해국(Aster sphathulifolius), 땅채송화(Sedum oryzifolium), 갯까치 수영(Lysimachia mauritiana)을 연구 재료로 사용하였다. 각 식물에서 근권세균을 각 9주씩 분리하고, 동정하여 이들 세균의 다양성을 조사하고 근권 토양의 세균 집단 조성을 분석하였다. 16S rDNA의 염기서열 분석 결과, 계통학적으로 총 4문 19종의 근권세균이 분리, 동정, 확인되었다. 또한 본 실험을 통하여 독도 자생식물 근권 균주의 최적 생육 환경이 확인되었다. S. oryzifolium는 Rhodobacterales목, Micrococcales목, Corynebacteriales목, Flavobacteriales목, Oceanospirillales목, Bacillales목의 세균 균주가 확인되었으며, 자생식물 L. mauritiana에서는 Micrococcales목, Flavobacteriales목, Rhizobiales목, Oceanospirillales목, Rhodobacterales목, Bacillales목의 세균균주가 확인되었다. 자생식물 A. sphathulifolius에서는 Flavobacteriales목, Rhizobiales목, Corynebacteriales목, Micrococcales목, Alteromonadales목 및 Bacillales목의 균주가 분리, 동정, 확인되었다. 본 연구를 바탕으로 3종의 자생식물에서 방선균문(Actinobacteria)과 프로테오박테리아문(Proteobacteria)에 속하는 근권세균이 많이 존재함을 확인할 수 있었다. Three plant species, Aster sphathulifolius, Sedum oryzifolium, and Lysimachia mauritiana, native to the Dokdo Islands in South Korea, were examined for rhizosphere microorganisms by using 16S rDNA sequences. Nine species of rhizosphere microorganisms were isolated from the three native plant species, respectively. Phylogenetic analysis showed that the microorganisms could be classified into 19 species belonging to four phyla (Actinobacteria, Bacteroidetes, Firmicutes and Proteobacteria), and the characteristics of the microbes were confirmed. Rhizosphere microorganisms from the six orders (Bacillales, Corynebacteriales, Flavobacteriales, Micrococcales, Oceanospirillales, and Rhodobacterales) were isolated from S. oryzifolium. From L. mauritiana, microbes belonging to the seven orders (Bacillales, Flavobacteriales, Micrococcales, Oceanospirillales, Rhizobiales, and Rhodobacterales) were isolated. From A. sphathulifolius, the six orders of rhizosphere microorganisms (Alteromonadales, Bacillales, Corynebacteriales, Flavobacteriales, Micrococcales, and Rhizobiales) were isolated. These data showed that Actinobacteria and Proteobacteria were the dominant phyla for the rhizosphere of all three plants. To confirm the bacterial diversity in rhizospheres, Shannon’s diversity index (H’) was used at the genus level. In these data, the rhizosphere from S. oryzifolium and L. mauritiana had more diverse bacteria compared to that from A. sphathulifolius.

      • KCI등재

        표준화 환자를 활용한 시뮬레이션 학습시나리오 개발 및 적용

        김예은(Ye-Eun Kim),강희영(Hee-Young Kang) 한국콘텐츠학회 2013 한국콘텐츠학회논문지 Vol.13 No.11

        본 연구의 목적은 표준화 환자를 활용한 신경계 환자 간호 시뮬레이션 학습을 위한 시나리오 개발과 그의 효과를 평가하기 위함이다. 단일군 사전 사후 설계이며 연구 참여자는 4학년 간호대학생이다. 본 연구는 자발성 뇌출혈 환자 사례의 시나리오를 개발하였고, 표준화 환자를 활용한 간호시뮬레이션 학습시나리오는 간호학생의 문제해결능력 및 임상수행능력을 향상시켰다. 본 연구를 통해 간호학생이 의식사정 등을 포함한 간호사정을 학습함으로써 보다 전문적인 간호사로 성장할 수 있는 계기가 될 수 있다는 점에서 의의가 있으며, 추후 표준화 환자를 활용한 시뮬레이션 학습 시나리오가 다양한 분야에서 개발되어야 함을 제언한다. This study was to develop the simulation learning scenario using standardized patients, and to evaluate the effect of it. This study was a pre-post test design with a single group and participants were recruited from fourth-year nursing students at a university. This study has developed the case scenario for a patient with spontaneous intracerebral hemorrhage and the simulation learning using standardized patients, which was applied in this study, had improved problem solving ability and clinical performance ability on nursing students. Through this study, the nursing student will grow up to be a professional nurse by learning the nursing assessment including consciousness assessment. Also, the simulation learning scenario using standardized patient should be developed in the various fields.

      • KCI등재

        염산 침출용액을 이용한 Pd/Al₂O₃ 촉매에서 고순도 팔라듐 회수

        김예은(Ye Eun Kim),변미연(Mi Yeon Byun),백재호(Jae Ho Baek),이관영(Kwan-Young Lee),이만식(Man Sig Lee) 한국청정기술학회 2020 청정기술 Vol.26 No.4

        팔라듐(Pd)은 희소금속임에도 불구하고 보석, 촉매 및 치과 소재와 같은 다양한 산업 응용 분야에 널리 사용되고 있다. 이러한 가운데 폐자원으로부터 고순도 Pd를 회수하는 기술들이 주목받고 있다. 본 연구에서는 염산 용액에서 팔라듐 침출 및 회수를 위한 최적 조건을 조사하였다. 염산 농도, 침출온도, 침출시간, 산화제 농도 및 광액 농도 등 다양한 실험조건에서 팔라듐 침출실험을 수행하였다. 염산농도 3 M, 산화제 3 vol%, 침출온도 80 ℃, 침출시간 60분에서 약 97.2%의 침출율을 나타내었다. 과산화수소/차아염소산나트륨의 비율은 침출용액 내 염소 이온 농도를 증가시켜 팔라듐 침출을 용이하게 하는 역할을 하는 것으로 확인하였다. 또한 pH 7에서 포름산을 첨가하여 80 ℃에서 30분 간 교반할 시 99.6% 순도를 가지는 팔라듐 분말을 회수할 수 있었다. 이는 포름산이 80 ℃에서 수소 가스와 이산화탄소로 분해되어 환원제 역할을 하였기 때문이라고 사료된다. 따라서 회수되어진 고순도 팔라듐 분말은 회로, 촉매 전구체 및 수술기구에 사용될 것으로 기대되어진다. Palladium (Pd) has been widely used in various industrial applications such as jewelry, catalyst, and dental materials despite its limited resources. It has been gaining attention to recover Pd with high purity from the spent materials. This study investigated the optimum conditions for the leaching and recovery of metallic Pd. The leaching parameters are HCl concentration, temperature, time, concentration of oxidants, and pulp density. 97.2% of Pd leaching efficiency was obtained in 3 M HCl with 3 vol% oxidants at 80℃ for 60 min. The ratio of hydrogen peroxide to sodium hypochlorite played a critical role in the leaching efficiency due to the supply of Cl- ions in the leachate. Moreover, the complete recovery of Pd in the leachate was achieved at 80℃ with 0.3 formic acid/leachate after adjusting the pH value of 7. This situation was ascribed to the decomposition of formic acid into hydrogen gas and carbon dioxide at 80℃. ICP-AES and XRD characterized the recovered Pd powder, and the purity of the recovered powder was found to be 99.6%. Consequently, the recovered Pd powder with high purity could be used in circuits, catalyst precursors, and surgical instruments.

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