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Higenamine이 단일심근세포의 Ca-전류 및 활동전압에 미치는 효과
김영덕(Kim, Young-Duck),서인석(So, In-Suk),엄융의(Earm, Yung-E) 대한생리학회 1987 대한생리학회지 Vol.21 No.2
The effects of higenamine were investigated in the single atrial and ventricular myocyte of the guinea pig by using patch clamp method. The results obtained were as follows: 1) Isoprenaline which is known to be β-agonist increased the duration of action potential and calcium current in ventricular cells. 2) Higenamine also increased the duration of action potential and calcium current in ventricular myocytes. And its effect was blocked by propranolol. 3) In the atrial cells, isoprenaline showed β-agonist effects, which were increasing the duration of action potential and calcium current same as in ventricular cells. 4) Higenamine, however, showed the opposite effects of β-agonist which were decreasing the duration of action potential and calcium current. The above results suggest that higenamine has the typical β-agonist effect in ventricular cells but inhibitory effect in atrial cells and this effect on atrium could be due to the reduction of calcium current.
이윤경,왕덕현,김원일,김영덕,김용제,김종업 경남대학교 신소재연구소 1998 論文集 Vol.10 No.-
본 연구는 초경합금의 형조방전가공시 가공조건을 변화시켜 실행하여 다음과 같은 결과를 얻었다. 공작물제거속도 및 전극소모비는 전류가 증가할수록 증가하고 있으나, 같은 조건의 전류에서 듀티팩터가 커지면 증가하다가 듀티팩터가 0.71에서는 감소하는 경향을 나타내었다. 표면거칠기는 듀티팩더와 전류의 영향을 받아 듀티팩터 및 전류가 증가할수록 거칠어졌으며, 듀티팩터의 영향을 더 크게 받는 것으로 나타났다. 공작물 형상측정에서 테이퍼량 및 가공확대여유는 전류와 듀티팩터의 영향을 많이 받지만 방전시간이 길수록 휴지시간이 짧을수록 크게 나타났다. 방전 가공면은 용융층이 재융착 과정에서 미세흠이 형성되고 듀티팩터가 커질수록 표면 균열이 크게 나타났다. Experimental research was conducted by changing the EDMachining conditions of tungsten carbide. From the experimental study, the following results were obtained. Material removal rate(MRR) and the wear rate of electrode were increased by the higher current. But in the same condition of the current, those results were increased by increasing the duty factor but they were decreased when the duty factor was 0.71. The surface roughness was increased by increasing the current and duty factor. It was found that the surface roughness was more affected by duty factor. The micro crack was found on the EDMed surface during the process of redeposition in the melting layer and the more increased the duty factor was, the higher the crack of surface was.