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Atrial Natriuretic Peptide in Thermal Acclimation in the Catfish, Silisnss fnsotus
김성주,류훈,이금영,김희선,조경우,Kim, Sung-Zoo,Ryu, Hoon,Lee, Geum-Yeong,Kim, Hee-Suhn,Cho, Kyung-Woo The Korean Society for Integrative Biology 1992 동물학회지 Vol.35 No.3
Responses of immunoreactive atrial natriuretic peptide (ir-ANP) to environmental temperature were studied in the freshwater catfish, Silums usotus, acclimated at various temperatures for one week. According to increase in environmental temperature, plasma sodium and chloride concentrations, and osmolality were significantly increased, while hematocrit showed a marked decrease. When the catfishes frere acclimated at cold $(3^{\circ}C)$ or warm $(18^{\circ}C)$ temperatures, ir-ANP contents in the atrium and bulbus arteriosus were significantly lower than those at $9^{\circ}C.$ However, ventricular contents of ir-ANP urere not different among the three groups.Levels of plasma ir-ANP in the catfish increased in response to the increment of acclimated temperature. On the basis of these results, we suggest that the environmental temperature may modulate synthesis and secretion of ir-hUP in the fish. We also suggest that changes of plasma ir-ANP levels may be associated with the control of body fluid homeostasis.
Acetaminophen 유도 간 손상에 대한 주적(酒敵)의 보호 효과
김성주,강형섭,신재석,설광화,허진,장선일,Kim, Sung-Zoo,Kang, Hyung-Sub,Shin, Jae-Suk,Xie, Guang-Hua,Huh, Jin,Jang, Seon-Il 대한한의학방제학회 2009 大韓韓醫學方劑學會誌 Vol.17 No.2
Acetaminophen (AP) is widely used as an over-the-counter analgesic and antipyretic drug. AP-induced hepatotoxicity is a common consequence of AP overdose and may lead to acute liver failure. In this study, we investigated the liver damage in mice using single dose (300 mg/kg) of AP and the possible protective effects of administration (50-200 mg/kg body weight) of Joo-Juk on acetaminophen-induced liver damage in mice. The alanine aminotransferase (ALT), and aspartate aminotransferase (AST) activities were determined in the plasma of mice. The effect of Joo-Juk on lipid peroxidation product thiobarbituric reacting substances (TBARS) and some antioxidant enzymes superoxide dismutase (SOD), catalase, d-aminolevulinate dehydratase ($\sigma$-ALA-D) activities, and gluthathione peroxidase (GPx), were also evaluated in the mouse liver homogenate. AP caused liver damage as evident by statistically significant increased in plasma activities of AST and ALT. There were statistically significant losses in the activities of SOD, catalase, $\sigma$-ALA-D, and GPx and an increase in TBARS in the liver of AP-treated group compared with the control group. However, Joo-Juk was able to counteract these effects. These results suggest that Joo-juk can act as hepato-protectant against AP toxicity and is a good candidate for further evaluation as an effective chemotherapeutic agent.
오현희(Hyun Hee Oh),황금택(Keum Taek Hwang),김무열(Muyeol Kim),이희권(Hee Kwon Lee),김성주(Sung Zoo Kim) 한국식품영양과학회 2008 한국식품영양과학회지 Vol.37 No.6
본 연구에서는 국내에서 재배되거나 야생의 나무딸기류 20 종류를 수집하여 무게, 수분함량, 과즙의 당도, pH, 산도, pH를 측정하고, 과즙의 당 조성 및 유기산 조성 분석하여 각각의 특성을 검토하였다. 실험에 사용한 나무딸기류 과일의 무게는 0.9~7.8 g이었고, 과일의 수분함량은 82.0~90.3%였다. 나무딸기류 과즙의 당도는 6.9~16.9%(Brix)로 다양하였다. HPLC로 분석한 나무딸기류 과즙의 당은 glucose(총당 함량의 40.7~84.0%(w/w))와 fructose(6.5~57.5%)가 주를 이루고 있었고, 일부 과일에는 sucrose와 xylose도 미량 존재하였다. 과즙의 pH는 2.8~3.9였고, 적정 산도는 0.6~2.9%(w/v, citric acid)였다. 나무딸기류 과즙의 유기산을 HPLC로 분석한 결과, citric acid(총산 함량의 14.6~87.5%(w/w))와 malic acid (9.6~87.1%)가 주를 이루고 있었고, 일부 과일에는 tartaric acid, succinic acid, oxalic acid 등이 함유되어 있었다. In this study, 20 kinds of raspberries and blackberries, cultivated or wild in Korea, were collected. Weight, moisture content, sugar content, sugar composition, pH, titratable acidity and acid composition of the fruits were determined. Weight of each of the fruits and moisture contents in the fruits were 0.9~7.8 g and 26~62%, respectively. The sugar contents in the fruit juices were 6.9~16.9% (Brix). The major sugars in the fruits were glucose (40.7~84.0% (w/w) of the total sugars) and fructose (6.5~57.5%). Sucrose and xylose were also detected in a small quantity. pH and titratable acidity of the berry juices were 2.8~3.9% (w/v, citric acid) and 0.6~2.9%, respectively. The major organic acids were citric acid (14.6~87.5% (w/w) of the total acids) and malic acid (9.6~87.1%). Succinic, tartaric and oxalic acids were also detected in a small amount.
저온에 노출한 드렁허리 (Monopterus albus)의 Renin 활성도, 혈장 전해질 및 삼투질 농도의 변화에 관하여
김성주,이금영,조경우 圓光大學校 醫科學硏究所 1987 圓光醫科學 Vol.3 No.2
Changes in plasma and renal renin activities, plasma electrolyte concentrations, and osmolality were studied in Rice eel (Monopterus albus) exposed to cold temperature. The plasma and renal renin activities, plasma sodium, chloride, and o-smolality were significantly lower in cold temperature than in room temperature exposed. A change in plasma osmolality correlated directly with the change of an environmental temperature. Plasma renin activity correlated closely with plasma sodium and chloride concentration in room temperature group but not in cold temperature group. On the basis of these data, we suggest that plasma and renal renin activities relate closely to the environmental temperature. We also suggest the plasma osmolality in cold temperature as well as in room temperature relates to plasma sodium concentration.
韓國産 납자루 亞科 魚類의 染色體와 ARM NUMBER
李金泳,蘇俊魯,金聖周 全北大學校 基礎科學硏究所 1982 基礎科學 Vol.5 No.1
Karyotypes of 12 species of the Acheilognathine fishes were studied using chromosomes of gill slit and kidney cells prepared by the flame drying technique. The results were as follows : 1. Numbers of chromosomes were classified into three patterns as 2n=48, 44, and 46. 2. In the 2n=48, No. of two-arm chromosome (TAC) and one-arm chromosome (OAC)were 12 or 14 pairs and 10 or 12 pairs, respectively. In the 2n=44, TAC and OAC were 14 or 12 and 8 or 10, severally, In the 2n=46, TAC was 2 pairs and OAC was 21 pairs. 3. Above results indicate that patterns of arm number(AN) were classified into four groups as AN=76, 72, 68, and 50. In the view of these results, we suggest that primitive chromosomal type of Acheilognathine fishes(cyprinidae) was 2n=46 and AN=50(R. notatus, R. suigensis).