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Effects of Scolopendrae corpus on Immune Response in Mice of Different Ages
김길섭,서운규,정지천,김철호,이동목,송해범,이항우,남경수 한국생명과학회 1998 한국생명과학회 학술발표회 Vol.20 No.-
To clarify the activating effects of Scolopendrae corpus on immunological function, its effect on primary and secondary antibodies production in mice of various ages was investigated. Scolopendrae corpus increased the number of both antibody producing cells(anti-IgM and anti-IgG producing plaque forming cells, PFC) and phagocytic activity of peritoneal macrophage. Futhermore, these phenomena were significantly increased with aging in mice. Scolopendrae corpus also increased natural killer cell activity concerning to cancer immunology. These results suggest that Scolopendrae corpus markedly increases the reduced activity in the elderly and activates the immune response in senescence mice.
오공(蜈蚣)이 노령(老齡)에 따른 mouse의 면역(免疫) 기능(機能)에 미치는 영향(影響)
김길섭,서운교,정지천,Kim, Gil-Seop,Seo, Un-Kyo,Jeong, Ji-Cheon 대한한방내과학회 1998 大韓韓方內科學會誌 Vol.19 No.1
To clarify the activating effects of Scolopendrae corpus on immunological function, its effect on primary and secondary antibodies production in mice of various ages was investigated. Scolopendrae corpus increased the number of both antibody producing cells(anti-IgM and anti-IgG producing plaque forming cells, PFC) and phagocytic activity of peritoneal macrophage. Futhermore, these phenomena were significantly increased with aging in mice. Scolopendrae corpus also increased natural killer cell activity concerning to cancer immunology. These results suggest that Scolopendrae corpus markedly increases the reduced activity in the elderly and activates the immune response in senescence mice.
오공(蜈蚣)이 마우스에서 2단계(段階) 발암화(發癌化) 과정(過程)에 미치는 영향(影響)
김길섭,황영근,윤철호,서운교,김종대,정지천,남경수,강정준,Kim, Kil-Sub,Hwang, Young-Guen,Yoon, Cheol-Ho,Seo, Un-Kyo,Kim, Jong-Dae,Jeong, Ji-Cheon,Nam, Kyung-Soo,Kang, Jeong-Jun 대한한방내과학회 1999 大韓韓方內科學會誌 Vol.20 No.1
To clarifiy the effects of Scolopendrae corpus(S-C) on turmor promotion in two-stage carcinogenesis in mice was investigated. In vivo system, S-C were seen to gave an inhibitory activity on TPA-induced mouse ear edema. In addition, the S-C were proved to have antitumor-promoting activity in two-stage mouse skin carcinogenesis induced by DMBA and two-stage mouse lung carcinogenesis induced by 4-NQO as a initiator plus TPA and glycerol as a promoter. Moreover, S-C significantly exhibited an cytolytic effect in $HepG_2$ cells and showed significant antitumor activity against Sarcoma-180 bearing mice by oral administration. These results suggest that S-C could be effective in adjuvant chemotherapy for human cancer.
김길섭,서운교,鄭智天 東國大學校韓醫學硏究所 1994 東國韓醫學硏究所論文集 Vol.3 No.-
Studying documents & papers on the cure of mate sterility to conclusion as follows. 1. The methodes of cure were applied Onbosinyang, Jaeumbosin, Soganheul, Joseubhwadam, Boickgihyul, Hwalhyeolhwaua, Boickbisn, etc. And the causes of disease were applied Sinyanghue, Sineumhue, Ganulgihe, Damseubneon, Gihwelyanghue, Gichehyeolul, Bisinyanghue, etc. 2. Prescription were applied Chanyukdan Ojayuenjonghwan on Sinyanghue, Yukmijihwan Jibekjihwanghwan on Sinuemhue, Sihosogansan Soyosan on Ganulgiche, Changchuldodamtang Bihebunchungeum on Damseubneon, Sibjyundaebotang Paljintang on Gihyeolyanghue, Sobokchu-kuatang Gueasengjungtang on Gichehyeolul, Sibjayukguntang Bisinssangbohwan on Bisinyanghue, etc. and Ojayunjonghwan being added in the base to cure another causes of disease as well as Sinhue. 3. The cause of disease were presonted to be Sinhue mostly ; Sinvanghue particulatly. And there were usually 25∼42years old, married lives of 3~8years, cure periods of 2∼5mon-ths, general effectiveness(approximately 76%), pregnancies(approximately 47%). 4, The methodes of cure in oriental medical prepared with the causes of disease in western one are showed in blow ; The cause of semen formation disorder is considered the methodes of cure in Onbosinyang, Jaeumbosin, Boickbin and the cause of functional ejaculation disorder in mind is considered the method of cure in Sogangegwu on the base in Bosin.