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        High-Resolution Actigraphic Analysis of ADHD: A Wide Range of Movement Variability Observation in Three School Courses – A Pilot Study

        감혜진,이기영,조선미,신윤미,박래웅 대한의료정보학회 2011 Healthcare Informatics Research Vol.17 No.1

        Objectives: This study was conducted to determine whether or not newly proposed high-resolution activity features could provide a superior analytic foundation compared to those commonly used to assess transitions in children’s activities, under circumstances in which the types of courses attended exert different situational effects on activity levels. Methods: From 153children at a local elementary school, 10 subjects with attention deficit hyperactivity disorder (ADHD) and 7 controls were recruited. Their activity data was collected using an actigraph while they attended school. Ratios of partitioned activity ranges (0.5-2.8 G) during the entire activity were extracted during three classes: art, mathematics, and native language (Korean). Extracted activity features for each participant were compared between the two groups of children (ADHD and control) using graphs and statistical analysis. Results: Activity distributions between ADHD and control groups for each class showed statistically significant differences spread through the entire range in art class compared to native language and mathematics classes. The ADHD group, but not the control group, experienced many significantly different intervals (> 50%) having low to very high activity acceleration regions during the art and languages courses. Conclusions: Class content appears to influence the activity patterns of ADHD children. Monitoring the actual magnitude and activity counts in a wide range of subjects could facilitate the examination of distributions or patterns of activities. Objective activity measurements made with an actigraph may be useful for monitoring changes in activities in children with ADHD in a timely manner.

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        Enchanted Life Space: Adding Value to Smart Health by Integrating Human Desires

        김주현,감혜진,박유랑,유소영,오지선,김영학,이재호 대한의료정보학회 2018 Healthcare Informatics Research Vol.24 No.1

        Objectives: Developments in advanced technology have unlocked an era of smart health, transforming healthcare practicesinside and outside hospitals for both medical staff and patients. It is now possible for patients to collect detailed healthdata using smartphones and wearable devices, regardless of their physical location or time zone. The use of these patientgenerateddata holds great promise for future healthcare advancements in many ways; however, current strategies for smarthealthtechnologies tend to focus on the smartness of the technology itself and on managing a particular disease or condition. Moreover, opportunities for people within the healthcare system to experience the benefits of these innovations are stilllimited. Methods: An expert workshop was held to discuss the current limitations of smart health, where each expert gave apresentation on their particular expertise, followed by an exchange of ideas for the purpose of drawing conclusions. Results:‘Smartness’ should not be the ultimate value for patients using smart technologies; instead of focusing on individual smartdevices, we should consider the space around people and their relation to each object so that the combination of space andobjects brings an ‘enchanted’ experience to user. Conclusions: An ‘enchanted’ experience can only be possible when monitoringprovides the user with a comfortable life and satisfies their needs and desires sufficiently. Only when the novelty of thedevice’s smartness effectively connects people with the space around them and focuses on human desires can it be cost effectiveand value creating.

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        Sudden Bispectral Index Reduction and Suppression Ratio Increase Associated with Bradycardia in a Patient Undergoing Breast Conserving Surgery

        조영흔,김재만,전상범,박세웅,감혜진,심우현,김성훈 대한신경집중치료학회 2018 대한신경집중치료학회지 Vol.11 No.1

        Background: The bispectral index (BIS) is a valuable indicator for measuring sedation levels and patient consciousness. Recent reports have highlighted its clinical value as an indicator for anesthesia-related cerebral hypoperfusion and ischemic brain damage. Case Report: A 55-year-old female patient underwent right breast conservation surgery during general anesthesia. During surgery, the patient experienced abrupt bradycardia (heart rate of 36 bpm) without hypotension. During bradycardia, her BIS was severely reduced from 45 to 20 along with elvated suppression ratio (50). After injection of 0.5mg of atropine, her BIS level was recovered, her heart rate was increased, and her suppression ratio was decreased. Conclusion: The patient recovered from anesthesia without showing any signs of neurological sequelae based on BIS level monitoring.

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        임상 데이터 웨어하우스 기반 후향적 시판 후 부작용조사: Fluoxetine 대상 적용 가능성 연구

        박만영,이영호,김은엽,김우재,감혜진,최종필,한태화,강운구,박래웅 대한의료정보학회 2009 Healthcare Informatics Research Vol.15 No.2

        Objective: Post-marketing surveillance (PMS) is an adverse events monitoring practice of pharmaceutical drugs on the market. Traditional PMS methods are labor intensive and expensive to perform, because they are largely based on manual work including phone-calling, mailing, or direct visits to relevant subjects. The objective of this study was to develop and validate a PMS methodology based on the clinical data warehouse (CDW). Methods: We constructed a archival DB using a hospital information system and a refined CDW from three different hospitals. Fluoxetine hydrochloride, an antidepressant, was selected as the target monitoring drug. Corrected QT prolongation on ECG was selected as the target adverse outcome. The Wilcoxon signed rank test was performed to analyze the difference in the corrected QT interval before and after the target drug administration. Results: A refined CDW was successfully constructed from three different hospitals. Table specifications and an entity-relation diagram were developed and are presented. A total of 13 subjects were selected for monitoring. There was no statistically significant difference in the QT interval before and after target drug administration (p=0.727). Conclusion: The PMS method based on CDW was successfully performed on the target drug. This IT-based alternative surveillance method might be beneficial in the PMS environment of the future.

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