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일차성 및 이차성 불면증 환자에서의 개별 인지행동치료의 임상적 효능
신윤미,차보석,임채미,신홍범,Shin, Youn-Mi,Cha, Bo-Seok,Lim, Chae-Mi,Shin, Hong-Beom 대한수면의학회 2010 수면·정신생리 Vol.17 No.1
목 적: 본 연구는 일차성 및 이차성 불면증 환자에서 인지행동치료(Cognitive Behavioral Therapy, 이하 CBT)의 임상적 효능을 평가하고자 하였다. 방 법: 2008년 1월부터 2009년 6월까지 일차의료기관 수면클리닉에 방문한 환자들을 대상으로 하였다. 전체 64명의 외래 환자가 모집되었으며, DSM-IV에 의거하여 진단 된 일차성 불면증 환자는 30명, 이차성 불면증 환자는 34명이었다. 환자들은 CBT 전후로 수면 일지, 수면에 대한 역기능적 신념 및 태도 척도(Dysfunctional Beliefs and Attitudes about Sleep Scale-16, 이하 DBAS) 및 상태-특성 불안척도(State-Trait Anxiety Inventory, 이하 STAI)를 각각 시행하였다. CBT는 1주 간격으로 7회, 1회당 40~50분 동안 개별적으로 진행하였다. 결 과: 일차성, 이차성 불면증 환자군 모두 입면 잠복기, 총 수면 시간, 수면 효율과 같은 수면 지표와 DBAS 점수의 유의한 호전을 보였다. 반복측정 분산분석에서는 두 군간에 시간에 따른 DBAS와 수면 지표의 유의한 차이는 없었다. 이차성 불면증에서의 CBT의 효과는 일차성 불면증에서의 효과와 동등하였다. 결 론: 이번 연구는 CBT가 일차의료 환경에서 일차성 및 이차성 불면증의 치료에 있어 효과적이라는 것을 시사한다. Objectives: This study aimed to evaluate the clinical efficacy of individual cognitive behavioral therapy (CBT) for Patients with Primary or Secondary Insomnia. Methods: Participants were recruited from a primary care sleep clinic from January 2008 to June 2009. The study sample included 64 outpatients with primary insomnia (n=30) and secondary insomnia (n=34) according to the criteria of DSM-IV. Participants completed sleep diaries, Dysfunctional Beliefs and Attitudes about Sleep Scale-16 (DBAS), State-Trait Anxiety Inventory (STAI) before CBT and shortly after completion of CBT. CBT was provided in 7 weekly, 40-50-minute individual therapy sessions. Results: Both groups of patients with primary and secondary insomnia showed significant improvement in the DBAS and sleep parameters including sleep onset latency, total sleep time, and sleep efficiency. Repeated-measures ANOVA of the DBAS and sleep parameters showed no significant group-by-time interactions between patients with primary and secondary insomnia, suggesting the efficacy of CBT for patients with secondary insomnia was equivalent to that of CBT for patients with primary insomnia. Conclusion: This study suggests that CBT is effective for the management of primary and secondary insomnia in a primary care setting.
신윤미,오연목,김미나,심태선,임채만,이상도,고윤석,김우성,김동순,홍상범 대한의학회 2011 Journal of Korean medical science Vol.26 No.7
It is difficult to differentiate pathogens responsible for pneumonia or colonization in patients with an endotracheal tube or in patients that have undergone tracheostomy. We evaluated the clinical usefulness of quantitative endotracheal aspirates cultures and sought to determine the result threshold level for positivity. The authors performed this retrospective cohort study between December 1, 2004 and January 31, 2006. Forty-five suspected pneumonia patients admitted to an intensive care unit (ICU) with quantitative bronchoalveolar lavage (BAL) and endotracheal aspirate (EA) culture results were enrolled. Using a threshold of 10^5 cfu/mL, 10 of the 45 (22.2%) quantitative EA cultures were positive, as compared with 7 (15.6%) BAL cultures. When BAL culture findings were used as the reference, the sensitivity and specificity of quantitative EA cultures were 85.7% and 89.5%, respectively, at a threshold of 10^5 cfu/mL, and 85.7% and 94.7%, respectively, at a threshold of 10^6 cfu/mL. Of the 10 EA culture positive patients, 2 patients with a result of -10^5 cfu/mL were BAL culture negative. The quantitative EA culture is a useful non-invasive tool for the diagnosis of pneumonia pathogens. It is suggested that a threshold level of 10^6cfu/mL is appropriate.
신윤미,정영기,임기영,오은영,조선미,이영문 대한의학회 2009 Journal of Korean medical science Vol.24 No.2
The aim of this study was to investigate predictors of adolescence suicidality in a longitudinal study. Additionally, the prevalence of deliberate self-harm behavior and suicide ideation at age 7 and during middle school were examined. Initial assessment data was obtained from 1998 to 2000, and a follow-up assessment was performed in 2006 when the original subjects became middle school students. The addresses and names of 1,857 subjects were located from the original data; they were 910 boys and 947 girls. The subjects were evaluated with the Korean version of the Child Behavior Checklist (K-CBCL), which was administered by the parents of the children, and by various demographic and psychosocial factors. They were reassessed using self reports on the Korea Youth Self Report (K-YSR); in particular, replies to items related to self-harm behavior and suicide ideation were recorded. A logistic regression analysis showed that the factors of gender, economic status, the overall amount of behavior problems, the tendency to internalizing and externalizing problems, somatic problems, thought problems, delinquent behavior, and aggressive behavior were independent predictors of adolescent suicide ideation and self-harm behavior. The importance of total behavior problems suggested that adolescent difficulty is a consequence of an accumulation of various risk factors. Accordingly, clinicians must consider a range of internalizing and externalizing issues, especially overall adaptation, for suicide intervention.