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RISS 인기검색어
- 검색키워드
- 저자 : ( Joo Han Lim ) (검색결과 745 건)
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金沂柱,李喜寶,金永錫,林漢旭 全北大學校 1980 論文集 Vol.22 No.-
A Study on failure strength of rock under uniaxial and triaxial compression tests was carried out for underground structural design in domestic and foreign countries recently. An experimental study was made for the core specimens of SANG-DONG tungsten mine. The results are as follows; 1. Failure strength was increasing gradually with increase of confining pressure. 2. Longitudinal and lateral strain increased in proportion to confining pressure under triaxial compression tests. 3. Stress-strain curves showed straight line to 62% of failure strength. 4. Effect of failure strength about porosity was 3.0% on the average and it represented lower value comparatively. 5. The values of triaxial compressive strength were distributed between 345 and 3082㎏/㎠, the mean value of which was 1063㎏/㎠. 6. The mean value of modulus of longitudinal elasticity(E) was 3.6X 10^5㎏/㎠ and poisson's ratio was 0.35.
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GT rotary file을 이용한 만곡 근관형성시 작업 효율 및 file 변형 발생에 관한 연구
신주희,백승호,배광식,임성삼,윤수한,김병현 대한치과보존학회 2001 Restorative Dentistry & Endodontics Vol.26 No.5
Root canal preparation process is of utmost importance in successful treatment of root canal. Also, one of the most important purpose of the root canal preparation is to enlarge the root canal three dimensionally without changing the curvature of the root canal. However, as the curvature of the root canal increases, there are many difficulties involved in formation of optimum root canal. Therefore, in order to solve the above mentioned problems, new developments in methods of root canal preparation and equipments for such purposes were made. Recently, vigorous studies about newly introduced engine-driven nitckel-ti-tanium rotary file are conducted. As shown in research results to dates, it is well established that the use of nickel-titanium file is better suited for curved root canal than stainless steel file in maintaining the curvature of root canal and reducing the deformation of root canal. However, it is also acknowledged that there are a few discrepancies in research results according to protocol, due to failure to remove variables in experiments. In addition, although it is recommended by the manufacturer that the GT rotary file should maintain a low rotational speed of 150∼350rpm and 'light pressure' as light as not to break the lead of a pencil, academic studies about the vertical force which is not yet standardized are not sufficiently explored. Therefore, this research devised and utilized a special research equipment to standardize the appropriate range of vertical force for GT rotary file through experiments by breaking of the lead of a pencil as expressed by the manufacturer and to accurately measure factors involved through repeating and recreating the environment of root canal preparation. Forming nine experimental groups by varying the vertical forces (150g, 220g, 300g) and rpm (150rpm, 250rpm, 350rpm), the effects of changing vertical forces and rpm on working efficiency were measured in terms of time expended in root canal preparation by crown-down method using a transparent resin block with 35 degree curvature and GT rotary file (z-test). The following research using this special research equipment that involved nine experimental groups and varying the vertical force for root canal preparation from 300g which is within the normal vertical force range to 700g and 1000g which fall outside the normal rpm range. The results were as follows : 1.Analysis of the experiment results revealed that the tome spent in root canal preparation decreased as the vertical forces and rpm increased (p<0.05). Also, the effects of rpm were greater than those of the vertical forces within the normal vertical force range (β-weight test) . 2.Observation of the deformation of GT rotary file revealed that deformation increases in a direct correlation with the vertical force increase and in a reverse correlation with the rpm decrease, In the case of the vertical forces close to the normal range, the probability of GT rotary file deformation were quite different depending on the rpm changes. In the case of◎eater tier◎cal forces, the occurrences of deformation of the file were more frequent regardless of the rpm changes. 3.Deformation and breakage of file were also commonly observed in the expended time measurement experiments and GT rotary file deformation experiments in which low speed rpm (150rpm) was used and at the curved portion of the resin block. Key words : GT rotary file, Crown-down method, Working efficiency, Vertical force, Rpm, Deformation and breakage of file
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김유민, 이한주, 오진헌, 임기조 충북대학교 컴퓨터정보통신연구소 2012 컴퓨터정보통신연구 Vol.20 No.1
In this paper, a novel type ultrasonic linear motor is proposed. The proposed motor consists of a ring type stator and a mover. They have spirals on their inner and outer surface, respectively. Along the spiral, a mover is travelled by a travelling extensional vibration mode of a ring type stator. Hence, a linear up-and-down motion is possible. Through the experimental results, we can verify the applicability regarding the autofocus lens driver. keywords : Ultrasonic linear motor, Autofocusing driver, ring type stator
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Irbesartan과 Lercanidipine의 병용요법이 고혈압 및 혈관재형성에 미치는 효과
이도형, 임태완, 조은지, 박현수, 정상혁, 한주희, 병창선 충남대학교 약학대학 의약품개발연구소 2017 藥學論文集 Vol.32 No.-
Hypertension is one of the major risk factor for cardiovascular disease and can lead to or make worse many complications, heart disease, atherosclerosis and diabetes. Thus, managing blood pressure effec tively using therapeutic drugs such as angiotensin II receptor blocker (ARB) and Ca2+ channel blocker (CCB) can be prevent other complications. Therefore, we investigated the synergistic effect of these two drugs, ir besartan and lercanidipine, for antihypertension, cardioprotection and antidiabetes. Irbesartan (28.74 mg/kg, 14.37 mg/kg) or lercanidipine (1.92 mg/kg, 0.96 mg/kg) alone or combination was administered to sponta-neously hypertensive rats (SHRs) and C57BL/6 mice. A two-week treatment of combination with irbesartan and lercanidipine significantly attenuated systolic blood pressure (SBP) and mean arterial pressure (MAP) compared with monotherapy. Futhermore. the combination therapy protected myocardial ischemia reperfusion injury more effectively than monotherapy. In vascular remodeling, combination therapy significantly diminished cuff -induced neointima formation and reduced serum -indllced vascular smooth muscle cells (VSMCs) pro-liferation compared with monotherapy. However, combination therapy had no significant synergistic effect of blood glucose regulation. Taken together, present study suggest that the combination therapy of irbesartan and lercanidipine may be more effective therapeutic strategy for the treatment of hypertension and related complications, myocardial infarction and arterial restenosis than monotherapy
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Lim, Joo-Han,Kim, Eun Sil,Chung, Moon-Hyun,Kang, Jae-Seung 대한감염학회 2008 감염과 화학요법 Vol.40 No.1
Azifomycins은 경도의 쯔쯔가무시병 치료에서 doxycycline에 비길만하며, 부작용도 적고 임신부나 소아에게도 투여할 수 있다. 드물게 심장 부정맥이 부작용으로 발생할 수 있다. 저자들은 중증 쯔쯔가무시병에서 정주용 azitomycin을 2번 정맥으로 투여한 직후, torsades de pointes가 발생한 예를 경험하였다. Cardioversion으로 정상 리듬으로 회복시켰고 항생제를 doxycycline으로 바꾼 후, 환자는 다른 합병증 없이 퇴원하였다. Azithromycin shows a comparable therapeutic efficacy to doxycycline against mild to moderate scrub typhus. It is safe enough to use in pregnant women or children less than 8 years of age, but may be associated with fatal cardiac dysrhythmia. Herein we report a case of scrub typhus in which torsades de pointes developed during treatment with intravenous azithromycin. A 63-year-o1d man with a history of hypertension and prolonged QT interval was admitted because of fever with duration of 13 days, rash, an eschar, and delirium. An initial electrocardiography showed atrial fibrillation with rapid ventricular response. Scrub typhus complicated by meningoencephalitis, pneumonitis, and possible myocarditis was diagnosed. Two 500 mg doses of azithromycin were infused over 30 minutes, 12 hours apart. The patient developed a cardiac arrest due to torsades de pointes 30 minutes after the second dose of azithromycin. After the patient was resuscitated successfully and the antibiotic was change to doxycycline. The patient eventually improved and was discharged without any sequelae.
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Aortocaval Fistula by Luetic Abdominal Aortic Aneurysm : Report of a case
Lim, Sang Hyun,Lee, Cheol Joo,Roh,Hwan-Kyu,Kim, Dae Jun,Han, Jung Sun,Shin, Joon Han,Kim, Han Soo 아주대학교 1996 아주의학 Vol.1 No.2
A 53-year-old male patient was operated on because of a spontaneous abdominal aortic aneurysm with aortocaval fistula. The fistula was successfully closed and bifurcated woven Dacron graft was used to replace the aneurysm. The patient had with characteristic signs and symptoms of aortic aneurysm with arteriovenous fistula. Proper diagnosis and prompt surgical repair of aortocaval fistula saved the patient. The use of rapid infusion system provided stable hemodynamics during the operation.
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Lim, Jiyoung,Kim, Young Joo,Yoon, Yongsook,Kim, Soon Ok,Kang, HyoJin,Park, Jungsun,Han, A. Reum,Han, Bokghee,Oh, Burmseok,Kimm, Kyuchan,Yoon, Bangwon,Song, Kyuyoung Elsevier 2006 Genomics Vol.87 No.3
<P><B>Abstract</B></P><P>The extent and pattern of linkage disequilibrium (LD) in the human genome provide important information for disease gene mapping. Previous studies have shown that LDs vary depending on chromosomal regions and populations. As the Asian samples of the International HapMap Project consisted of Japanese and Chinese populations, it was of interest whether we could use the HapMap data as a reference to carry out association studies of common complex diseases in a closely related population, such as Koreans. We have compared the LD and recombination patterns defined by single-nucleotide polymorphisms (SNPs) in ENCODE region ENm010, chromosome 7p15.2, in Korean, Japanese, and Chinese samples and further tested the robustness of tagSNPs among the Asian samples. We genotyped 792 SNPs in 500 kb (chromosome 7: 26699793–27199792, NCBI build 34) from 90 unrelated Koreans by fluorescence polarization detection and compared the data with Asian data from the HapMap project. Despite some differences in the position of high LD region boundaries, the overall patterns of LD were remarkably similar across the three samples, reflecting strong genetic affinities among them. Furthermore, the haplotype tag SNP transferability across the three samples was greater than 90%. Our results support the initial suggestion that the populations genotyped in the HapMap project might serve as reference populations for the selection of tagSNPs in association studies [The International HapMap Consortium, The International HapMap Project, Nature 426 (2003) 789–796. <ce:cross-ref refid='bib1'>[1]</ce:cross-ref>].</P>
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( Joo Han Lim ),( Moon Hee Lee ),( Hyung Gil Kim ),( Yong Woon Shin ),( Hyeon Gyu Yi ),( Seok Hwan Shin ),( Yoon Seok Hur ),( Chul Soo Kim ),( Hye Jeong Chang ) 대한소화기기능성질환·운동학회 2010 Gut and Liver Vol.4 No.4
Background/Aims: Elderly patients with advanced gastric cancer (AGC) have generally been excluded from clinical trials, and there are few data available on the treatment of these patients. The efficacy of palliative S-1 monotherapy as a first-line treatment regimen for elderly patients has not been well elucidated. Methods: For this study, 25 AGC patients were enrolled between January 1, 2007 and March 31, 2009; 4 cases were recurrent AGC and 21 cases were metastatic AGC at the time of diagnosis. These patients received S-1 therapy at a dose of 40 mg/m2 twice daily for 14 days every 3 weeks. All of the patients were older than 70 years. Results: The median follow-up duration, the median progression-free survival, and the overall survival time were 8.7 months (range, 4.9 to 12.5 months), 4.9 months (range, 3.5 to 6.3 months), and 10.8 months (range, 6.6 to 15.0 months), respectively. Grade 3/4 nonhematologic toxicities were rare. Grade 3/4 neutropenia was noted in two patients. The partial response rate was 21.7% and stable disease was observed in 34.8% of the patients. Two patients (8%) died due to chemotherapy-associated toxicity during treatment (septic shock/intracranial hemorrhage). Conclusions: Oral S-1 chemotherapy seems to be effective as a first-line treatment regimen for elderly patients with metastatic or recurrent AGC. However, elderly patients receiving S-1 treatment should undergo continuous toxicity monitoring, since they are highly susceptible to adverse effects. (Gut Liver 2010;4:503-507)
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