Use of radiotherapy in patients with palliative double bypass for locally advanced pancreatic adenocarcinoma

Juan Glinka,Federico Diaz,Augusto Alva,Oscar Mazza,Rodrigo Sanchez Claria,Victoria Ardiles,Eduardo de Santibañ,es,Juan Pekolj,Martí,n de Santibañ,es 대한방사선종양학회 2018 Radiation Oncology Journal Vol.36 No.3

Purpose: Pancreatic cancer (PC) has not changed overall survival in recent years despite therapeutic efforts. Surgery with curative intent has shown the best long-term oncological results. However, 80%–85% of patients with these tumors are unresectable at the time of diagnosis. In those patients, first therapeutic attempts are minimally invasive or surgical procedures to alleviate symptoms. The addition of radiotherapy (RT) to standard chemotherapy, ergo chemoradiation, in patients with locally advanced pancreatic cancer (LAPC) is still controversial. The study aims to compare outcomes in patients with a double bypass surgery due to LAPC treated or not with RT. Materials and Methods: A retrospective cohort study of patients with double bypass for LAPC were registered and divided into two groups: treated or not with postoperative RT. Baseline characteristics, postoperative complications, those related to RT and their relation to the main event (mortality) were compared. Results: Seventy-four patients were included. Surgical complications between the groups did not offer significant differences. Complications related to RT were mostly mild, and 86% of patients completed the treatment. Overall survival at 1 and 2 years for patients in the exposed group was 64% and 35% vs. 50% and 28% in the non-exposed group, respectively (p = 0.11; power 72%; hazard ratio = 0.53; 95% confidence interval, 0.24–1.18). Conclusion: We observed a tendency for survival improvement in patients with postoperative RT. However, we’ve not had enough power to demonstrate this difference, possibly due to the small sample size. It is indispensable to develop randomized and prospective trials to guide more specific treatment lines in this patients.

Agri Agra Law Compliance among Philippine Banks: Trends and Insights

Cherry Lou R,Nuñ,ez,Arnie-Gil DLR,Hordejan,Jeanette Angeline B,Madamba 아시아무역학회 2020 Journal of Asia Trade and Business Vol.7 No.1

Purpose - This study examined the trends of compliance by the Philippine banking sector and offered insights and suggestions based on the findings. Being an agricultural country, the agricultural (agri) and agrarian (agra) sector of the Philippines is constantly in need of funds from the banking and financial sector in order to meet operational requirements if it is to develop and grow. However, since most farmers and farming enterprises are not bankable due to strict banking standards and requirements including collateral, lack of financing remains a chronic challenge. Thus, a mechanism formulated by the Philippine government together with the Bangko Sentral ng Pilipinas (BSP) also known as the Central Bank of the Philippines, included an Agri-Agra Law requiring all banks within its jurisdiction to channel one-fourth of their net loanable funds to agriculture to spur development and economic growth in the countryside. Design/Methodology/Approach - To accomplish the research objectives, this study utilized descriptive and trend analyses. Findings - Results showed that while there appeared to be compliance relative to the Agri requirement of the law, banks as a whole remained non-compliant in terms of the Agra requirement of the law such that instead of direct lending to agribusinesses and agrarian reform beneficiaries, banks preferred to comply via alternative modes of compliance. Research Implications - This implies that banks still consider farmers, agricultural and agro-based enterprises and agrarian beneficiaries as lending risks and minimally profitable to do business with. It is suggested therefore that changes be introduced in the implementing rules and regulations of the Agri-Agra Law to address the risk issues and make it more financially rewarding for banks to lend to the agricultural and agrarian sector through the introduction of incentives.

Airway management through submental derivation: a safe and easily reproduced alternative for patients with complex facial trauma

Fernando Gonzá,lez-Magañ,a,Hé,ctor Omar Malagó,n-Hidalgo,Eugenio Garcí,a-Cano,Roberto Vilchis-Ló,pez,Adriana Fentanes-Vera,Fernan-Alejandra Ayala-Ugalde 대한구강악안면외과학회 2018 대한구강악안면외과학회지 Vol.44 No.1

Objectives: Airway management in patients with panfacial trauma is complicated. In addition to involving facial lesions, such trauma compromises the airway, and the use of intermaxillary fixation makes it difficult to secure ventilation by usual approaches (nasotracheal or endotracheal intubation). Submental airway derivation is an alternative to tracheostomy and nasotracheal intubation, allowing a permeable airway with minimal complications in complex patients. Materials and Methods: This is a descriptive, retrospective study based on a review of medical records of all patients with facial trauma from January 2003 to May 2015. In total, 31 patients with complex factures requiring submental airway derivation were included. No complications such as bleeding, infection, vascular, glandular, or nervous lesions were presented in any of the patients. Results: The use of submental airway derivation is a simple, safe, and easy method to ensure airway management. Moreover, it allows an easier reconstruction. Conclusion: Based on these results, we concluded that, if the relevant steps are followed, the use of submental intubation in the treatment of patients with complex facial trauma is a safe and effective option.

필리핀 딜리만 대학교 학생들의 재난 준비도에 대한 횡단연구

Yra Marie Calamiong,Danielle Marie Parreñ,o 중앙대학교 한국인적자원개발전략연구소 2020 역량개발학습연구 Vol.15 No.4

필리핀은 지리적 위치로 인해 재난에 취약한 국가이다. 이에 따라 필리핀 대학생들은 재난에 대비하는 것이 중요하다고 할 수 있다. 본 연구는 필리핀 딜리만 대학교 학부생들을 대상으로 재난위기 경감(Disaster Risk Reduction; DRR) 훈련을 받은 학생과 받지 않은 학생 간에 차이가 있는지 알아보는 것을 목적으로 한다. 횡단적 혼합 접근법을 통해 DRR 교육을 받은 학생 78명과 교육을 받지 않은 학생 67명에게 Tuladhar 외(2015)의 설문에 응답하도록 하였다. 응답 자료의 타당성을 확보하기 위해 표적집단면접(Focus Group Discussion)을 실시하였다. 수집된 데이터에 대해SPSS 23.0을 사용하여 통계 분석한 결과, DRR 훈련을 받은 집단과 받지 않은 집단 간에 유의한차이가 있었으나 그 효과는 미비한 것으로 나타났다. 또한 Qualyzer를 활용한 주제분석 결과, 재난 지식, 재난 대비 및 준비 행동, 재난 적응, 재난 인식, 재난 위험 인식과 같은 유의미한 주제들이 도출되었다. 교육의 효과성을 제고하기 위해서는 딜리만 대학 차원에서 DRR 교육을 재검토하고 학생들을 위한 다른 훈련 수단을 탐색하는 것이 요구된다. The Philippines is a disaster-prone country due to its geographical location. Hence, it is important for Filipino university students to be prepared during a disaster. This study aims to know whether there is a difference between UP Diliman undergraduate students with and without Disaster Risk Reduction (DRR) training. Using a cross-sectional mixed-method approach, students with DRR training (n=78) and without training (n=67) were asked to answer the questionnaire adapted from Tuladhar and colleagues (2015). A Focus Group Discussion was done to substantiate the data. Statistical analysis using SPSS 23 revealed that despite the significant differences between the group of students with and without DRR training, the effect is rather small. Thematic analysis using Qualyzer revealed significant themes on disaster knowledge, preparedness and readiness behaviors, adaptation, awareness, and risk perception. It is recommended to reexamine DRR training in UP Diliman for effectiveness and explore other means of training for students.

A Disrupted-in-Schizophrenia 1 Gene Variant is Associated with Clinical Symptomatology in Patients with First-Episode Psychosis

Javier Vá,zquez-Bourgon,Ignacio Mata,Roberto Roiz-Santiá,ñ,ez,Rosa Ayesa-Arriola,Paula Suá,rez Pinilla,Diana Tordesillas-Gutié,rrez,José,Luis Vá,zquez-Barquero,Benedicto Cr 대한신경정신의학회 2004 PSYCHIATRY INVESTIGATION Vol.1 No.2

Objective-DISC1 gene is one of the main candidate genes for schizophrenia since it has been associated to the illness in several populations. Moreover, variations in several DISC1 polymorphisms, and in particular Ser704Cys SNP, have been associated in schizophrenic patients to structural and functional modifications in two brain areas (pre-frontal cortex and hippocampus) that play a central role in the genesis of psychotic symptoms. This study tested the association between Ser704Cys DISC1 polymorphism and the clinical onset of psychosis. Methods-Two hundred and thirteen Caucasian drug-naïve patients experiencing a first episode of non-affective psychosis were genotyped for rs821616 (Ser704Cys) SNP of the DISC1 gene. The clinical severity of the illness was assessed using SAPS and SANS scales. Other clinical and socio-demographic variables were recorded to rule out possible confounding effects. Results-Patients homozygous for the Ser allele of the Ser704Cys DISC1 SNP had significantly (p<0.05) higher rates at the positive symptoms dimension (SAPS-SANS scales) and hallucinations item, compared to Cys carriers. Conclusion-DISC1 gene variations may modulate the clinical severity of the psychosis at the onset of the disorder.

Performance of carbon fiber added to anodes of conductive cement-graphite pastes used in electrochemical chloride extraction in concretes

M. J. Pellegrini-Cervantes,C. P. Barrios-Durstewitz,R. E. Nú,ñ,ez-Jaquez,F. J. Baldenebro-Lopez,R. Corral-Higuera,S. P. Arredondo-Rea,M. Rodriguez-Rodriguez,O. Llanes-Cardenas,R. Beltran-Chaco 한국탄소학회 2018 Carbon Letters Vol.26 No.-

Pollution of chloride ion-reinforced concrete can trigger active corrosion processes that reduce the useful life of structures. Multifunctional materials used as a counter-electrode by electrochemical techniques have been used to rehabilitate contaminated concrete. Cement-based pastes added to carbonaceous material, fibers or dust, have been used as an anode in the non-destructive Electrochemical Chloride Extraction (ECE) technique. We studied the performance of the addition of Carbon Fiber (CF) in a cement-graphite powder base paste used as an anode in ECE of concretes contaminated with chlorides from the preparation of the mixture. The experimental parameters were: 2.3% of free chlorides, 21 days of ECE application, a Carbon Fiber Volume Fraction (CFVF) of 0.1, 0.3, 0.6, 0.9%, a lithium borate alkaline electrolyte, a current density of 4.0 A / m2 and a cement/graphite ratio of 1.0 for the paste. The efficiency of the ECE in the traditional technique using metal mesh as an anode was 77.6% and for CFVF of 0.9% it was 90.4%, with a tendency to increase to higher percentages of the CFVF in the conductive cement-graphite paste, keeping the pH stable and achieving a homogeneous ECE in the mass of the concrete contaminated with chlorides.