http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Yufeng Zheng(Yufeng Zheng),Xue Liu(Xue Liu),Na Li(Na Li),Aimei Zhao(Aimei Zhao),Zhiqiang Sun(Zhiqiang Sun),Meihua Wang(Meihua Wang),Judong Luo(Judong Luo) 대한방사선종양학회 2023 Radiation Oncology Journal Vol.41 No.2
Purpose: To analyze the gene mutation, immune infiltration and tumor growth of primary tumor and distant tumor under different treatment modes. Materials and Methods: Twenty B16 murine melanoma cells were injected subcutaneously into the of both sides of the thigh, simulating a primary tumor and a secondary tumor impacted by the abscopal effect, respectively. They were divided into blank control group, immunotherapy group, radiotherapy group, and radiotherapy combined immunotherapy group. During this period, tumor volume was measured, and RNA sequencing was performed on tumor samples after the test. R software was used to analyze differentially expressed genes, functional enrichment, and immune infiltration. Results: We found that any treatment mode could cause changes in differentially expressed genes, especially the combination treatment. The different therapeutic effects might be caused by gene expression. In addition, the proportions of infiltrating immune cells in the irradiated and abscopal tumors were different. In the combination treatment group, T-cell infiltration in the irradiated site was the most obvious. In the immunotherapy group, CD8+ T-cell infiltration in the abscopal tumor site was obvious, but immunotherapy alone might have a poor prognosis. Whether the irradiated or abscopal tumor was evaluated, radiotherapy combined with anti-programmed cell death protein 1 (anti-PD-1) therapy produced the most obvious tumor control and might have a positive impact on prognosis. Conclusion: Combination therapy not only improves the immune microenvironment but may also have a positive impact on prognosis.
A kinetic model for glycerol chlorination in the presence of acetic acid catalyst
Zheng-Hong Luo,Xiao-Zi You,Hua-Rong Li 한국화학공학회 2010 Korean Journal of Chemical Engineering Vol.27 No.1
A kinetic model for the chlorination of glycerol with hydrochloric acid in the use of acetic acid as catalyst is presented in this study. The model is based on a comprehensive chlorination mechanism, taking the formation of 1,3-dichloro-2-propanol and 2,3-dichloro-1-propanol into account while ignoring the formation of any intermediate in the chlorination system. Simulations were carried out under different chlorination conditions to calculate the concentrations of the main chemical species in the reaction system. The validity of the model was examined via a comparison of the calculated data with the experimental data on the chlorination of glycerol with hydrochloric acid at 363-393 K. The results show the model is capable of describing the chlorination performance with good agreement with experimental data.
Luo Xiao-Jing,He Ming-Ming,Liu Jia,Zheng Jia-Bo,Wu Qi-Nian,Chen Yan-Xing,Meng Qi,Luo Kong-Jia,Chen Dong-Liang,Xu Rui-Hua,Zeng Zhao-Lei,Liu Ze-Xian,Luo Hui-Yan 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-
Esophageal squamous cell carcinoma (ESCC) is one of the most life- and health-threatening malignant diseases worldwide, especially in China. Long noncoding RNAs (lncRNAs) have emerged as important regulators of tumorigenesis and tumor progression. However, the roles and mechanisms of lncRNAs in ESCC require further exploration. Here, in combination with a small interfering RNA (siRNA) library targeting specific lncRNAs, we performed MTS and Transwell assays to screen functional lncRNAs that were overexpressed in ESCC. TMPO-AS1 expression was significantly upregulated in ESCC tumor samples, with higher TMPOAS1 expression positively correlated with shorter overall survival times. In vitro and in vivo functional experiments revealed that TMPO-AS1 promotes the proliferation and metastasis of ESCC cells. Mechanistically, TMPO-AS1 bound to fused in sarcoma (FUS) and recruited p300 to the TMPO promoter, forming biomolecular condensates in situ to activate TMPO transcription in cis by increasing the acetylation of histone H3 lysine 27 (H3K27ac). Targeting TMPO-AS1 led to impaired ESCC tumor growth in a patient-derived xenograft (PDX) model. We found that TMPO-AS1 is required for cell proliferation and metastasis in ESCC by promoting the expression of TMPO, and both TMPO-AS1 and TMPO might be potential biomarkers and therapeutic targets in ESCC.
Zheng, Ping,Pu, Bei,Yu, Bing,He, Jun,Yu, Jie,Mao, Xiangbing,Luo, Yuheng,Luo, Junqiu,Huang, Zhiqing,Luo, Chenggui,Wang, Shaohui,Chen, Daiwen Asian Australasian Association of Animal Productio 2018 Animal Bioscience Vol.31 No.6
Objective: The objective of this experiment was to compare the effects of adding 130 mg/kg Cu from either copper sulfate (CS) or tribasic copper chloride (TBCC) on growth performance, mineral deposition in tissues, and the excretion in feces of pigs as well as changes in the mineral contents in tissues and feces when the supplemental Cu level was decreased from 130 mg/kg to 10 mg/kg. Methods: A total of 72 pigs ($32.6{\pm}1.2kg$) were randomly assigned to a CS diet or a TBCC diet with 6 pens per treatment. The trial lasted 102 d and included 3 phases (phase 1, 1 to 30 d; phase 2, 31 to 81 d; and phase 3, 82 to 102 d). The supplemental levels of Cu in the 2 treatments were 130 mg/kg in phase 1 and 2 and 10 mg/kg in phase 3. Results: The results showed that pigs fed the CS diet tended to have higher average daily gain than pigs fed the TBCC diet during d 1 to 81 (p<0.10). Compared with CS, TBCC increased the activities of aspartate transaminase (AST), ceruloplasmin, and superoxide dismutase in serum on d 30 (p<0.05). The TBCC decreased the Cu level in the liver on d 81 (p<0.05) and increased the Mn level in the liver on d 102 (p<0.05). The concentration of Cu in feces sharply decreased when the supplemental Cu level in diet changed from 130 mg/kg to 10 mg/kg in both diets (p<0.05). Conclusion: The result suggested that TBCC and CS had no significant difference on growth performance but TBCC had higher activities of AST and antioxidant enzymes and lower liver Cu than CS when pigs fed diets with 130 mg Cu /kg diet.
Xiaogang Zheng,Liping Wang,Yuanliang Zhou,Meiyin Luo,Hongyan Li,Zongyang Bo,Weixin Zheng,Chenggong Chang,Jing Wen,Jinmei Dong 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.126 No.-
Biochar-based composites have been intensively applied in wastewater treatment. To boost theadsorption-photocatalytic capacity of biochar for dyes elimination, S-doped biochar was commodifiedby NiS and MgO (NiS-Mg/S-BC) via the one-pot sulfurization at high temperature. The functional groupsin NiS-Mg/S-BC provided the abundant vacant sites for RhB adsorption and photocatalysis, and the junctioninterface among NiS, MgO, and S-doped biochar was likely to form the channels for the separationand transfer of photo-induced e-/h+ pairs. NiS-Mg/S-BC presented the better adsorption-photocatalyticcapacity of RhB than S-doped biochar, NiS and MgO modified biochar. Langmuir and second-order modelswell described the adsorption behaviors of NiS-Mg/S-BC. The removal efficiency of optimal 2b-NiS-Mg/SBCfor 400 mg/L RhB solution was 96.98% within 120 min, and its adsorption capacity based on secondordermodel was 802.49 mg g1. The photo-corrosion induced to the declined removal efficiency of 2b-NiS-Mg/S-BC to 94.13% after five cycles.
Dongjun Luo,Xiaoyun Wu,Xinwei Zheng,Yuping Hu 보안공학연구지원센터 2014 International Journal of Security and Its Applicat Vol.8 No.6
Cloud computing platforms are usually constructed as trusted virtual platforms based on trusted computing technologies. This is one of the most effective approaches to resolve cloud computing security problems. However, the protection of sensitive data in trusted virtual platforms is an important problem needed to be resolved. In this paper, we proposed a novel authorization protocol. The protocol assembled the functions of OIAP, OSAP and AACP protocols, and prevented all known attacks in existing authorization protocols. Moreover, it satisfied the property of exclusivity and was compatible with TCG TPM command formats. The protocol effectively protects the sensitive data from unauthorized accesses in trusted cloud computing platforms.
Cong Luo,Ying Zheng,Yongqing Xu,Haoran Ding,Chuguang Zheng,Changlei Qin,Bo Feng 한국화학공학회 2015 Korean Journal of Chemical Engineering Vol.32 No.5
A novel calcium-based pellet was prepared by extrusion of sol-gel CaO powder and cement with high aluminum- based content. Limestone was used for comparison. The cyclic CO2 capture performance and carbonation kinetics of the sorbents were investigated in a thermogravimetric analyzer (TGA). The changes in phase and microstructure were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and Brunauer Emmet Teller (BET) surface area, respectively. The results indicate that the pellet consisted of CaO and Ca12Al14O33 after initial calcination. Limestone reactivity decreased dramatically with the increase in the cycle number, whereas the pellet showed a relatively stable cyclic CO2 capture performance with high reactivity. The CO2 capture capacity of the pellet achieved 0.43 g CO2/g sorbent after 50 cycles at 650 oC and 850 oC for carbonation and calcination, respectively. Moreover, the pellet obtained fast carbonation rates with slight decay after multiple cycles. The porous microstructure of the pellet contributed to the high reactivity of the sorbent during high temperature reactions, and the support material of Ca12Al14O33, enhanced the cyclic durability of the calcium-based sorbents.
Study of Deflection Routing from an Information-theoretic Perspective
Xinwei Zheng,Yuping Hu,Dongjun Luo,Xiaoyun Wu 보안공학연구지원센터 2015 International Journal of Future Generation Communi Vol.8 No.1
Deflection routing is an effective way to improve the efficiency and reliability of data transmission in the network. Information theory, which is the foundation of channel communications, has not yet had a direct impact on network communications. In this paper, we study the deflection routing processes of point-to-point networks from an information-theoretic perspective. It is found that the packet routing processes, which can further be divided into path determination and path switching, are quite analogous to channel communications. And such a corresponding relationship makes it possible to analyze routing processes and its performance with models and concepts in the information theory.
Cong Luo,Ying Zheng,Ning Ding,Chuguang Zheng 한국화학공학회 2011 Korean Journal of Chemical Engineering Vol.28 No.4
To improve the stability of CaO adsorption capacity for CO_2 capture during multiple carbonation/calcination cycles, modified CaO-based sorbents were synthesized by sol-gel-combustion-synthesis (SGCS) method and wet physical mixing method, respectively, to overcome the problem of loss-in-capacity of CaO-based sorbents. The cyclic CaO adsorption capacity of the sorbents as well as the effect of the addition of La_2O_3 or Ca_12Al_14O_33 was investigated in a fixed-bed reactor. The transient phase change and microstructure were characterized by X-ray diffraction (XRD) and field emission scanning electron microscopy (FSEM), respectively. The experimental results indicate that La_2O_3 played an active role in the carbonation/calcination reactions. When the sorbents were made by wet physical mixing method,CaO/Ca_12Al_14O_33 was much better than CaO/La_2O_3 in cyclic CO_2 capture performance. When the sorbents were made by SGCS method, the synthetic CaO/La_2O_3 sorbent provided the best performance of a carbonation conversion of up to 93% and an adsorption capacity of up to 0.58 g-CO_2/g-sorbent after 11 cycles.