Review of the Macrophya regia group (Hymenoptera: Tenthredinidae) from China with the descriptions of two new species

Ze‐Jian Li,Meng-Meng LIU,Meicai Wei,Chao-dong Zhu 한국곤충학회 2018 Entomological Research Vol.48 No.5

The Macrophya regia group is reviewed and five species are recognized from China, among them two new species, M. acutiserrula Li, Liu & Wei sp. nov. and M. frontalis Li, Liu & Zhu sp. nov., and three known species, M. regia Forsius 1930, M. maculoclypeatina Wei et al. 2003, and M. xiaoi Wei et al. 2003. A key to the Chinese species of the Macrophya regia group are provided.

Computation and Analysis of Electric Field Distribution Under Lightning Impulse Voltage for 1000‑kV Gas‑Insulated‑Switchgear Spacer

Wei Yang,Taiyun Zhu,Yu Tian,Shenglong Zhu,Xi Yang 대한전기학회 2020 Journal of Electrical Engineering & Technology Vol.15 No.4

The electric feld distribution is critical to the insulation structure design of 1000-kV gas-insulated-switchgear (GIS) equipment. At present, it is not difcult to obtain the electric feld distribution under commercial frequency sinusoidal voltage; however, for lightning impulse voltage, the electric feld distribution is commonly substituted by electrostatic analysis under the peak voltage. As a result, this treatment may not embody the characteristics of the dielectric constant changing with frequency. In this paper, a frequency-domain mathematical model for transient analysis is established. The measured broadband frequency dielectric spectrum for the medium of a GIS spacer is well ftted by a H–N function model with three relaxation peaks. The transient analysis for a 1000-kV GIS spacer is realized by superposing the responses to the sinusoidal and direct current components of the lightning impulse waveform. The potential and electric feld regulation for a 1000-kV GIS spacer under lightning impulse voltage is presented and analyzed. Furthermore, the computed results from traditional electrostatic analysis are introduced for comparison. The results indicate that the electrostatic analysis increases the computed electric feld strength at the surface of the GIS spacer, while it decreases that at the interface between the GIS spacer and center conductor. It could provide computational support for the insulation structure design of 1000-kV GIS spacers.

Genome-wide analyses reveal the extent of opportunistic STAT5 binding that does not yield transcriptional activation of neighboring genes

Zhu, Bing-Mei,Kang, Keunsoo,Yu, Ji Hoon,Chen, Weiping,Smith, Harold E.,Lee, Daeyoup,Sun, Hong-Wei,Wei, Lai,Hennighausen, Lothar Oxford University Press 2012 Nucleic acids research Vol.40 No.10

<P>Signal Transducers and Activators of Transcription (STAT) 5A/B regulate cytokine-inducible genes upon binding to GAS motifs. It is not known what percentage of genes with GAS motifs bind to and are regulated by STAT5. Moreover, it is not clear whether genome-wide STAT5 binding is modulated by its concentration. To clarify these issues we established genome-wide STAT5 binding upon growth hormone (GH) stimulation of wild-type (WT) mouse embryonic fibroblasts (MEFs) and MEFs overexpressing STAT5A more than 20-fold. Upon GH stimulation, 23 827 and 111 939 STAT5A binding sites were detected in WT and STAT5A overexpressing MEFs, respectively. 13 278 and 71 561 peaks contained at least one GAS motif. 1586 and 8613 binding sites were located within 2.5 kb of promoter sequences, respectively. Stringent filtering revealed 78 genes in which the promoter/upstream region (−10 kb to +0.5 kb) was recognized by STAT5 both in WT and STAT5 overexpressing MEFs and 347 genes that bound STAT5 only in overexpressing cells. Genome-wide expression analyses identified that the majority of STAT5-bound genes was not under GH control. Up to 40% of STAT5-bound genes were not expressed. For the first time we demonstrate the magnitude of opportunistic genomic STAT5 binding that does not translate into transcriptional activation of neighboring genes.</P>

Key Point Detection in 3D Reconstruction Based On Human-Computer Interaction

Zhu Shi Wei,Zhang Xiao Guo,Lv Jia Dong,Wang Qing 보안공학연구지원센터 2015 International Journal of Multimedia and Ubiquitous Vol.10 No.1

Aiming at solving problem of points’ redundancy caused by full automatically detecting points and the problem of large workload caused by picking all points manually, I advanced a new method of picking points which is based on Human-Computer Interaction in our 3D reconstruction platform after automatically detecting points. We first detected and matched points automatically and got the homograph matrix between two images, then projected points which were picked by hand on the one image to the other image, at last we would search the interesting feature points in the neighborhood of corresponding points in the two images. Experiments have shown that this method decreases the redundancy brought by large number of points and successfully finds the important feature points, so it lays a good foundation for 3D reconstruction.

An Isolated Microlens Observed from <i>K2</i> , <i>Spitzer</i> , and Earth

Zhu, Wei,Udalski, A.,Huang, C. X.,Novati, S. Calchi,Sumi, T.,Poleski, R.,Skowron, J.,Mró,z, P.,Szymań,ski, M. K.,Soszyń,ski, I.,Pietrukowicz, P.,Kozłowski, S.,Ulaczyk, K.,Pawlak, M.,Be American Astronomical Society 2017 ASTROPHYSICAL JOURNAL LETTERS - Vol.849 No.2

AUGMENTING WFIRST MICROLENSING WITH A GROUND-BASED TELESCOPE NETWORK

Wei Zhu,Andrew Gould 한국천문학회 2016 Journal of The Korean Astronomical Society Vol.49 No.3

Augmenting the Wide Field Infrared Survey Telescope ({\it WFIRST}) microlensing campaigns with intensive observations from a ground-based network of wide-field survey telescopes would have several major advantages. First, it would enable full two-dimensional (2-D) vector microlens parallax measurements for a substantial fraction of low-mass lenses as well as planetary and binary events that show caustic crossing features. For a significant fraction of the free-floating planet (FFP) events and all caustic-crossing planetary/binary events, these 2-D parallax measurements directly lead to complete solutions (mass, distance, transverse velocity) of the lens object (or lens system). For even more events, the complementary ground-based observations will yield 1-D parallax measurements. Together with the 1-D parallaxes from \wfirst~alone, they can probe the entire mass range $M\gtrsim M_\oplus$. For luminous lenses, such 1-D parallax measurements can be promoted to complete solutions (mass, distance, transverse velocity) by high-resolution imaging. This would provide crucial information not only about the hosts of planets and other lenses, but also enable a much more precise Galactic model. Other benefits of such a survey include improved understanding of binaries (particularly with low mass primaries), and sensitivity to distant ice-giant and gas-giant companions of \emph{WFIRST} lenses that cannot be detected by \emph{WFIRST} itself due to its restricted observing windows. Existing ground-based microlensing surveys can be employed if \emph{WFIRST} is pointed at lower-extinction fields than is currently envisaged. This would come at some cost to the event rate. Therefore the benefits of improved characterization of lenses must be weighed against these costs.

Appropriate nitrogen application enhances saponin synthesis and growth mediated by optimizing root nutrient uptake ability

Wei, Wei,Ye, Chen,Huang, Hui-Chuan,Yang, Min,Mei, Xin-Yue,Du, Fei,He, Xia-Hong,Zhu, Shu-Sheng,Liu, Yi-Xiang The Korean Society of Ginseng 2020 Journal of Ginseng Research Vol.44 No.4

Background: Cultivation of medicinal crops, which synthesize hundreds of substances for curative functions, was focused on the synthesis of secondary metabolites rather than biomass accumulation. Nutrition is an important restrict factor for plant growth and secondary metabolites, but little attention has been given to the plasticity of nutrient uptake and secondary metabolites synthesis response to soil nitrogen (N) change. Methods: Two year-field experiments of Sanqi (Panax notoginseng), which can synthesize a high level of saponin in cells, were conducted to study the effects of N application on the temporal dynamics of biomass, nutrient absorption, root architecture and the relationships between these parameters and saponin synthesis. Results: Increasing N fertilizer rates could improve the dry matter yields and nutrient absorption ability through increasing the maximum daily growth (or nutrient uptake) rate. Under suitable N level (225 kg/ha N), Sanqi restricted the root length and surface and enhanced the root diameter and N uptake rate per root length (NURI) to promote nutrient absorption, but the opposite status of Sanqi root architecture and NURI was found when soil N was deficient. Furthermore, increasing N rates could promote the accumulation of saponin in roots through improving the NURI, which showed a significant positive relationship with the content of saponin in the taproots. Conclusion: Appropriate N fertilizer rates could optimize both root architecture and nutrient uptake efficiency, then promote both the accumulation of dry matter and the synthesis of saponins.

Transcriptome analysis of colchicine-induced tetraploid Kiwifruit leaves with increased biomass and cell size

Zhu Yanyan,Tang Wei,Tang Xiaofeng,Wang Lihuan,Li Wei,Zhang Qian,Li Mingzhang,Fang Congbing,Liu Yongsheng,Wang Songhu 한국식물생명공학회 2021 Plant biotechnology reports Vol.15 No.5

Colchicine-induced polyploidization has been extensively utilized in plant-breeding programs to increase biomass and overall yield of various crop species. Chromosome doubling usually increases the plant size and cell size. However, the underly- ing mechanisms remain elusive. In this study, we showed that 0.1% colchicine is an optimized concentration for inducing tetraploidization of Actinidia chinensis var. chinensis ‘Hongyang’, a commercially important diploid kiwifruit cultivar. The tetraploid plants showed increased plant height, leaf size, and biomass, as compared with the corresponding diploid plants. Scanning electron microscopy and histological analysis indicated that the leaf cell size was significantly increased in the tetraploid plants. Our further transcriptome analysis revealed the 5922 differentially expressed genes between the diploid and tetraploid plants. Gene Ontology analysis enriched the cell wall-related genes, including the pectin methylesterases (PMEs) and expansins (EXPs), both of which play a critical role in cell wall loosening and extension. The increased expression of PME and EXP genes might contribute to the increased cell size in the tetraploid plants. Together, our work indicated that tetraploidization increases the organ and cell size in kiwifruit, possibly by enhancing the cell wall extensibility.

Target engagement of ginsenosides in mild cognitive impairment using mass spectrometry-based drug affinity responsive target stability

Zhu, Zhu,Li, Ruimei,Qin, Wei,Zhang, Hantao,Cheng, Yao,Chen, Feiyan,Chen, Cuihua,Chen, Lin,Zhao, Yunan The Korean Society of Ginseng 2022 Journal of Ginseng Research Vol.46 No.6

Background: Mild cognitive impairment (MCI) is a transitional condition between normality and dementia. Ginseng is known to have effects on attenuating cognitive deficits in neurogenerative diseases. Ginsenosides are the main bioactive component of ginseng, and their protein targets have not been fully understood. Furthermore, no thorough analysis is reported in ginsenoside-related protein targets in MCI. Methods: The candidate protein targets of ginsenosides in brain tissues were identified by drug affinity responsive target stability (DARTS) coupled with label-free liquid chromatography-mass spectrometry (LC-MS) analysis. Network pharmacology approach was used to collect the therapeutic targets for MCI. Based on the above-mentioned overlapping targets, we built up a proteineprotein interaction (PPI) network in STRING database and conducted gene ontology (GO) enrichment analysis. Finally, we assessed the effects of ginseng total saponins (GTS) and different ginsenosides on mitochondrial function by measuring the activity of the mitochondrial respiratory chain complex and performing molecular docking. Results: We screened 2526 MCI-related protein targets by databases and 349 ginsenoside-related protein targets by DARTS. On the basis of these 81 overlapping genes, enrichment analysis showed the mitochondria played an important role in GTS-mediated MCI pharmacological process. Mitochondrial function analysis showed GTS, protopanaxatriol (PPT), and Rd increased the activities of complex I in a dose-dependent manner. Molecular docking also predicted the docking pockets between PPT or Rd and mitochondrial respiratory chain complex I. Conclusion: This study indicated that ginsenosides might alleviate MCI by targeting respiratory chain complex I and regulating mitochondrial function, supporting ginseng's therapeutic application in cognitive deficits.

Optimization design and dynamic stability analysis of 3-DOF cable-driven parallel robot with an elastic telescopic rod

Wei Zhu,Jiahong Liu,Kuanxiang Shi,Fei Qi,Huiping Shen,Zhu Xu,Zhilong Ma 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.9

This paper proposes a three degree-of-freedoms (DOFs) cable-driven parallel robot (CDPR), which is actuated by three groups of parallel cables and tensioned by an elastic telescopic rod with a passive spring. Firstly, the architecture of the robot is briefly illustrated with emphasis on the three parallelogram arrangements of the cables and composition of elastic telescopic rod structure. This robot has larger workspace and greater tension than previous under-constrained CDPRs. Secondly, the kinematic and dynamic models of the robot are established. On this basis, the parameters of the spring installed in the telescopic rod are optimized and determined considering both the acceleration and cable force through using the differential evolution (DE) algorithm. Thirdly, dynamic stability analysis of the robot under impulsive disturbances is performed according to the Gauss principle of least constraint (GPLC). The results of a simulation case show that this robot has better dynamic stability in comparison with conventional under-constraint CDPR because of the presence of the elastic telescopic rod. The measurement results in the workspace are obtained through dynamic simulation. Finally, the experiments are performed based on numerical simulation. The feasibility of the CDPR is verified via the experiments and simulations.