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HDRE: Coverage Hole Detection with Residual Energy in Wireless Sensor Networks
Yun-zhou Zhang,Xiaohua Zhang,Wenyan Fu,Zeyu Wang,Honglei Liu 한국통신학회 2014 Journal of communications and networks Vol.16 No.5
Coverage completeness is an important indicator forquality of service in wireless sensor networks (WSN). Due to limitedenergy and diverse working conditions, the sensor nodes havedifferent lifetimes which often cause network holes. Most of the existingmethods expose large limitation and one-sidedness becausethey generally consider only one aspect, either coverage rate or energyissue. This paper presents a novel method for coverage holedetection with residual energy in randomly deployed wireless sensornetworks. By calculating the life expectancy of working nodesthrough residual energy, we make a trade-off between network repaircost and energy waste. The working nodes with short lifetimeare screened out according to a proper ratio. After that, the locationsof coverage holes can be determined by calculating the jointcoverage probability and the evaluation criteria. Simulation resultshows that compared to those traditional algorithms without considerationof energy problem, our method can effectively maintainthe coverage quality of repairedWSN while enhancing the life spanof WSN at the same time.
Zhou, Yun-Feng,Zhang, Guang-Bo,Qu, Ping,Zhou, Jian,Pan, Hui-Xin,Hou, Jian-Quan Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.10
Background: Prostate cancer (Pca) is one of the most common complex and polygenic diseases in men. The X-ray repair complementing group 1 gene (XRCC1) is an important candidate in the pathogenesis of Pca. The purpose of this study was to evaluate the association between single nucleotide polymorphisms in the XRCC1 gene and susceptibility to Pca. Materials and Methods: XRCC1 gene polymorphisms and associations with susceptibility to Pca were investigated in 193 prostate patients and 188 cancer-free Chinese men. Results: The c.910A>G variant in the exon9 of XRCC1 gene could be detected by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and DNA sequencing methods. Significantly increased susceptibility to prostate cancer was noted in the homozygote comparison (GG versus AA: OR=2.95, 95% CI 1.46-5.42, ${\chi}^2$=12.36, P=0.001), heterozygote comparison (AG versus AA: OR=1.76, 95% CI 1.12-2.51, ${\chi}^2$=4.04, P=0.045), dominant model (GG/AG versus AA: OR=1.93, 95% CI 1.19-2.97, ${\chi}^2$=9.12, P=0.003), recessive model (GG versus AG+AA: OR=2.17, 95% CI 1.33-4.06, ${\chi}^2$=8.86, P=0.003) and with allele contrast (G versus A: OR=1.89, 95% CI 1.56-2.42, ${\chi}^2$=14.67, P<0.000). Conclusions: These findings suggest that the c.910A>G polymorphism of the XRCC1 gene is associated with susceptibility to Pca in Chinese men, the G-allele conferring higher risk.
Zhang, Zhi-Guo,Li, Gang,Feng, Da-Yun,Zhang, Jian,Zhang, Jing,Qin, Huai-Zhou,Ma, Lian-Ting,Gao, Guo-Dong,Wu, Lin Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.1
Several recent studies have showed that the n-myc downstream regulated gene 2 (NDRG2) is a new tumor suppressor gene, and that it plays an important role in tumor suppression in several cancers or cancer cell lines. However, few studies focused on its function in neuroblastoma cells. In the present investigation, we demonstrated that NDRG2 overexpression inhibited their proliferation. Using a cDNA microarray, we found that overexpression of NDRG2 inhibited the expression of cysteine-rich protein 61 (CYR61), a proliferation related gene. From our research, CYR61 may partially hinder NDRG2-mediated inhibition of cell proliferation. Overexpression of NDRG2 resulted in accumulation of cells in the G1 phase, which was accompanied by upregulation of p21 and p27 and downregulation of CDK4 and cyclin D1. Taken together, these data indicate that NDRG2 inhibits the proliferation of neuroblastoma cells partially through suppression of CYR61. Our findings offer novel insights into the physiological roles of NDRG2 in neuroblastoma cell proliferation, and NDRG2 may prove to be effective candidate for the treatment of children with neuroblastoma.
An intelligent method to design die profile for rubber forming of complex curved flange part
Ling‑Yun Zhang,Shuai Zhou,Tian‑Zhang Zhao,Yi‑Pan Zeng 한국정밀공학회 2019 International Journal of Precision Engineering and Vol.20 No.1
Rubber forming is an important forming process for the manufacture of aircraft sheet metal parts. The springback is one of the main defects in rubber forming. Classical springback compensation by displacement adjustment method using finite simulation is not satisfactory. In this research, the algorithms of compensating the arc and flange surface of complex curved flange with correction formula are proposed by experiment. The correction formula was developed based on the CATIA V5 R19 using Component Application Architecture. Compensate profile is presented including surface pick up, line pick up, division, compensation, extending, and trimming. The die profile of part with complex curved flanges in aircraft could be designed rapidly. It was found that the forming pressure has a little effect on the springback. This is within the tolerance limits of the part. The results reveal the method can achieve the industrial part precisely. The method is demonstrated on an aircraft wing rib part.
Risk Effects of GST Gene Polymorphisms in Patients with Acute Myeloid Leukemia: A Prospective Study
Zhou, Lei,Zhu, Yan-Yun,Zhang, Xiao-Dong,Li, Yang,Liu, Zhuo-Gang Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.6
Glutathione S-transferase (GST) enzyme levels are associated with risk of many cancers, including hematologic tumours. We here aimed to investigate the relationships between GSTM1, GSTT1 and GSTP1 polymorphisms and the risk of AML. Genotyping of GSTs was based upon duplex polymerase-chain-reactions with the confronting-two-pair primer (PCR-CTPP) method in 163 cases and 204 controls. Individuals carrying null GSTT1 genotype had a 1.64 fold risk of acute leukemia relative to a non-null genotype (P<0.05). A heavy risk was observed in those carrying combination of null genotypes of GSTM1 and GSTT1 and GSTP1 Val allele genotypes when compared with those carrying wild genotypes, with an OR (95% CI) of 3.39 (1.26-9.26) (P<0.05). These findings indicate that genetic variants of GST and especially the GSTT1 gene have a critical function in the development of AML. Our study offers important insights into the molecular etiology of AML.
Yun-Li Cao,Lei Wang,Li-Long Zhou,Bao-Hua Xu,Yan-Yan Diao,Suojiang Zhang 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.65 No.-
A novel type of heteropolyacids, CTAB-CsH3PMo11VO40 (CTA-CsPAV), was developed by a method of emulsion synthesis using cetyltrimethyl ammonium bromide (CTAB) as the structure promoter, which was applied as a catalyst in the oxidation of methacrolein (MAL) to methacrylic acid (MAA) with fixed-bed reactor. The structure and property of CTA-CsPAV were characterized by FT-IR, XRD, nitrogen adsorption-desorption, NH3-TPD, SEM, XPS, and so on. The structure-performance relationship of CTA-CsPAV was systematically studied, wherein the influence of surface area, acidity, redox property of CTA-CsPAV were focused and discussed. Importantly, the long-term performance of CTA-CsPAV was also investigated.
Zhang, Le-Ying,Wang, Jia-Qi,Yang, Yong-Xin,Bu, Deng-Pan,Li, Shan-Shan,Zhou, Ling-Yun Asian Australasian Association of Animal Productio 2011 Animal Bioscience Vol.24 No.2
Bovine whey protein expression patterns of colostrum are much different from that of milk. Moreover, bovine colostrum is an important source of protective, nutritional and developmental factors for the newborn. However, to our knowledge, no research has been performed to date using a comparative proteomic method on the changes in the bovine whey proteome during the transition from colostrum to milk. This study therefore separated whey protein of days 1, 3, 7 and 21 after calving using two dimension electrophoresis. Differentially expressed proteins at different collection times were identified using high-performance liquid chromatography in tandem with mass spectrometry (LC/MS) and validated by enzyme-linked immunosorbent assay (ELISA) in order to understand the developmental changes in the bovine whey proteome during the transition from colostrum to milk. The expression patterns of whey protein of days 1 and 3 post-partum were similar except that immunoglobulin G was down-regulated on day 3, and four proteins were found to be down-regulated on days 7 and 21 compared with day 1 after delivering, including immunoglobulin G, immunoglobulin M, albumin, and lactotransferrin, which are involved in immunity and molecule transport. The results of this study confirm the comparative proteomic method has the advantage over other methods such as ELISA and immunoassays in that it can simultaneously detect more differentially expressed proteins. In addition, the difference in composition of milk indicates a need for adjustment of the colostrum feeding regimen to ensure a protective immunological status for newborn calves.
Study on economic performances of multi-span suspension bridges part 1: simple estimation formulas
Zhang, Li-Wen,Xiao, Ru-Cheng,Sun, Bin,Jiang, Yang,Zhang, Xue-Yi,Zhuang, Dong-Li,Zhou, Yun-Gang,Tu, Xue Techno-Press 2013 Structural Engineering and Mechanics, An Int'l Jou Vol.47 No.2
A study on economic performances of consecutive multi-span suspension bridges is carried out. In this part of the study, material amount and structural cost estimation formulas of the bridges is derived based on the structural ultimate carrying capacity. The bridge cost includes the part of superstructure and the part of substructure. Three types of bridge foundations, bored piles, concrete caissons and floating foundations, are considered in substructure. These formulas are to be used for the parametric study of the bridge cost in order to define its more economical layout under different conditions in the part two of the study.
Preparation of b-Ca3(PO4)2 bioceramic powderfrom calcium carbonate and phosphoric acid q
Yun Zhang,Guangfu Yin,Shifu Zhu,Dali Zhou,Yuehua Wang,Yong Li,Lin Luo 한국물리학회 2005 Current Applied Physics Vol.5 No.5
When preparing b-tricalcium phosphate (b-TCP) with Ca(NO3)2 or Ca(OH)2 as the raw materials, because of the problem ofltering, it is dicult to industrialize traditional methods. In this paper,b-TCP was prepared with calcium carbonate and phospho-ric acid. According to XRD spectrum, the precursor of this system is octacalcium phosphate (OCP) [Ca8H2(PO4)6Æ5H2O] instead ofnon-stoichiometric hydroxyapatite (HA) obtained from traditional methods, and thermodynamics mechanism of the reaction wasalso studied. The crystalb-TCP powders were obtained after the precursor had been calcined at 8501150.C for 2 h. SEM imagesshowed that hardening could eliminate the reunion to a great extent, and obtain dispersiveb-TCP powders with a particle diameterbetween 0.5 and 2.0l m. The main advantages of this process over traditional methods are the fast reaction rate, the easy ltering,the ne particle size and the minimum impurity..