충남지역 초염기성암체의 암석학적 연구

우영균,서만철,Woo, Young-Kyun,Suh, Man-Cheol 한국지구과학회 2000 한국지구과학회지 Vol.21 No.3

Ultramafic rocks in Choongnam area are mainly serpenitinites which are parent rock of talc and asbestos ore deposits. About 10 $^{\circ}$ NNE-trending parallel serpentinites masses occur as discontineous isolated lenticular intrusive bodies in Precambrian gneiss complex between Hongseong-Kwangcheon line and Onyang-Cheongyang line. The sizes of serpentinites vary from several centimeters to 1 kilometer in width and from several meters to 5 kilometers in length. The serpentinites show high SiO$_2$(39.99wt.% in average), MgO(38.46wt % in average), Cr(>1011ppm), Ni(>1660ppm), and Co(>80ppm). Most serpentinites contain serpentine more than 50%. Some serpentines contain original minerals such as olivine, pyroxene and chromite. Also, serpentinites body may contain a little serpentinized peridotite, and some talc and asbestos ore deposits. The original rocks of the serpentinites interpreted as Alpine type ultramafic rocks, and dunite and/or harzburgite which were originated from slightly depleted upper mantle(30${\sim}$40km deep), and emplaced in the crust through the large fault zones. It seems that main serpentinization from the original rocks was occurred during greenschist and/or amphibolite facies regional metamorphism in Choongnam area. 충남지역의 초염기성암체는 주로 활석과 석면광상의 모암을 이루는 사문암체로서 홍성-광천과 온양-유구-청양을 연결하는 선 내부의 선캄브리아기 편마암복합체내에서 북북동 방향에 따라 단속적으로 평행하게 발달하는 10여개조의 렌즈상관입암체들이다. 사문암체의 규모는 폭 수십 cm${\sim}$1km, 연장 수 m${\sim}$5km로서 곳에 따라 그 규모가 다양하다. 이 사문암들은 주로 SiO$_2$(평균 39.99wt.%)와 MgO(평균 38.46wt.%)로 구성되었고, Cr(>1011ppm), Ni(>1660ppm) 및 Co(>80ppm)의 함량이 많다. 이 사문암들은 주로 사문석의 양이 50% 이상인 것이 대부분이며, 부위에 따라 기원암의 잔류광물인 감람석과 휘석, 크롬철석 등이 발견되는 데 사문암체 내에는 부분적으로 이들 잔류광물의 함량이 50% 이상 되는 사문석화감람암과 활석 및 석면광체를 포함한다. 충남지역 사문암의 기원암은 알파인형 초염기성암으로서 약간 결핍된 상부 맨틀(깊이: 30${\sim}$40km)기원의 더나이트 내지 해즈버자이트였으며, 대규모 단층을 따라 상승한 것으로 해석된다. 이들 사문암의 기원암으로부터의 주 사문석화작용은 충남지역에서 일어난 녹색편암상 내지 각섬암상의 광역변성작용시에 일어난 것으로 해석된다.

전신성 홍반성낭창에서 발생한 무혈성 골괴사

우영균 ( Young Kyun Woo ),장주해 ( Ju Hai Chang ),김용식 ( Yong Sik Kim ),권순용 ( Soon Yong Kwon ),김기원 ( Ki Won Kim ),김양수 ( Yang Soo Kim ) 대한고관절학회 1995 Hip and Pelvis Vol.7 No.1

We took a retrospective assessment about the relationships to steroid therapy with 12 patients of AVN in SLE, comparing with the control cases which were composed of 25 patients of SLE followed up more than 5 years but free from evidence of AVN, who had been treated at Catholic University Medical College from 1986 to 1992. Based on results of above assessment, we carried out comparative analysis of above 2 groups to delineate the statistical significance between AVN and steroid therapy in SLE using Student's t-test, and its each items of statistical analysis were as follows; initial cumulative dosage on 1, 3, 6 months, average monthly dosage, average monthly dosage of pulse therapy and average monthly dosage of maintenance therapy throughout follow up period. In addition, we also reported the author's clinical experience in the orthopaedic management of 12 AVN patients in SLE with a respect of age & sex distribution, interval between diagnosis of SLE and AVN, involvement sites, radiologic stage especially in femoral head, treatment method and complication of treatment. This retrospective study was relatively fragmentary but shows that both initial higher steroid therapy and average dosage per months seem to be related with eventual development of AVN in SLE. In addition, the average monthly dosage of pulse therapy seems to have an influence on development of AVN in SLE also. But, the more distinct cause of AVN and the role of steroid in SLE may be elucidated through the further prospective attempt with an elaborate plan in concert with medical doctors.

슬관절 십자인대에 발생한 결절종

우영균(Young-Kyun Woo),이화성(Hwa-Sung Lee),권순용(Soon-Yong Kwon),김기원(Ki-Won Kim),이광열(Kwang-Yeol Lee) 대한정형외과학회 1999 대한정형외과학회지 Vol.34 No.3

충남 예산지구 활석광상의 기원암과 활석화작용

우영균,이동우,Woo, Young-Kyun,Lee, Dong-Woo 한국지구과학회 2001 한국지구과학회지 Vol.22 No.6

충남 예산지구 활석광상지역에는 선캄브리아기의 유구편마암을 관입하고 쥬라기 흑운모화강암과 백악기의 산성 및 염기성 암맥의 관입을 받은 시대미상의 초염기성암체가 있다. 이 초염기성암체는 주로 사문암이고, 소량의 각섬암과 주로 사문암으로부터 형성된 활석광체를 포함한다. 이 사문암들은 사문석 반정과 layering의 발달정도에 따라 S1 ${\sim}$ S5의 5개 암석단위로 구분된다. 그러나 이들의 구성광물 및 화학조성들이 유사한 것으로 보아 사문암의 기원암은 동일마그마 기원의 감람암(dunite와 pyroxene peridotite)으로 해석된다. 사문암의 기원암인 감람암은 유구편마암이 받은 각섬암상의 광역변성작용시에 사문석화작용을 받아 사문암으로 되었고, 이 사문암으로부터의 주 활석화작용은 파쇄대를 따라 상승한 열수에 의한 열수변질작용으로 해석된다. Ultramafic rocks in the Yesan talc ore deposits area are unknown age plutonic rocks which intruded PreCambrian Yoogoo gneiss, and were intruded by Jurassic biotite granite, and Cretaceous acidic and mafic dykes. The ultramafic rocks consist mainly of serpentinite with some amphibolite and talc ore body. The serpentinites are divided 5 rock types (S1${\sim}$S5) on the basis of the developed degree of serpentine phenocrysts and layerings. It seems that the original rocks of the serpentinites were co-magmatic peridotites (dunite and pyroxene peridotite). Main serpentinization from the original rocks was occurred during amphibolite facies regional metamorphism in Choongnam area which Yoogoo gneiss was affected. Main steatitization from the serpentinites was hydrothermal alteration by ascended hydrothermal fluid through crush zones.

슬관절 전방십자인대 신연 손상에 따른 기질 금속 단백 분해 효소(MMP)-2의 발현

우영균(Young Kyun Woo),송석환(Seok Whan Song),권순용(Soon Yong Kwon),이화성(Hwa Sung Lee),김영훈(Young Hoon Kim) 대한정형외과학회 2006 대한정형외과학회지 Vol.41 No.4

목적: 조직 재형성 과정은 손상된 조직의 자연 치유에 필수적이다. 세포외 기질 분해에 관여하는 기질 금속단백 분해효소(matrix metalloproteinase, MMP)가 이 과정에서 중요한 역할을 하는데, 본 연구는 전방십자인대의 손상에 따른 MMP-2의 발현을 알아보고자 하였다. 재료 및 방법: MMP-2의 지속적인 발현 여부를 파악하기 위해 쥐에서 대퇴골-전방십자인대-경골 복합체를 얻어 신연 손상을 가한 후 1주일간 관찰하였다. 그 후 인대 복합체를 세 군으로 나누어, 제1군은 5 N 및 12 N으로 10, 30, 60분 동안, 제2군은 5와 15 N의 힘으로 5, 10, 30, 60 및 120분 동안, 제3군에서는 5, 8, 10, 12 및 15 N 하에 각각 30 및 60분 동안 손상을 주었다. MMP-2의 발현은 0.05% gelatine zymography를 이용하여 검사하였다. 결과: 인대 손상 후 MMP-2의 지속적인 분비를 관찰할 수 있었으며, 발현 강도는 손상 받은 시간이나 가해진 힘의 크기에 비례하여 증가하였다. 인대 조직 자체의 검사에서는 배양액의 결과보다 전구형의 발현 강도는 미약했으나, 활성형은 더욱 뚜렷이 나타났으며, 손상 시간 및 크기에 따라 발현 정도는 역시 증가하였다. 결론: MMP-2는 인대 손상 후에 즉각적으로 발현되었으며, 강도는 손상 시간이나 가해진 힘에 비례하여 증가하였다. MMP-2의 발현이 인대 손상 후 진행되는 조직 재형성기 과정에서 중요한 역할을 할 것으로 생각된다. Purpose : Tissue remodeling is essential for the natural healing of damaged tissue. The matrix metalloproteinases (MMPs) that degrade the extracellular matrix to play a central role in this process. This study was designed to examine the basic relationship between MMP-2 and anterior cruciate ligament (ACL) injury. Materials and Methods : After the femur-ACL-tibia complex was harvested from rats, the continuous release of MMP-2 in the stretch group was evaluated. The complexes were divided into three groups. To stretch the complexes, in group I, 5 and 12 N weights were used for 10, 30, and 60 minutes. In group Ⅱ, 5 and 15 N weights were used for 5, 10, 30, 60, and 120 minutes. And in group Ⅲ, 5, 8, 10, 12, and 15 N weights were used for 30 and 60 minutes. MMP-2 activity was evaluated using 0.05% gelatin zymography. Results : MMP-2 was expressed and the signal intensity was increased according to the stretch duration and magnitude. In the tissue analysis, active MMP-2 was markedly present and the expression was increased in response to the stretch in the supernatant samples. Conclusion : MMP-2 was released immediately after ligament injury and its activity was increased in proportion to the stretch duration and magnitude. It is believed that MMP-2 expression plays an important role in the remodeling process after an ACL injury.

정형외과, 줄기세포 그리고 세포치료

우영균 ( Young Kyun Woo ) 대한고관절학회 2013 Hip and Pelvis Vol.25 No.4

류마토이드 관절염 환자의 무시멘트 인공 슬관절 치환술과 항류마토이드 약제의 효과

우영균(Young-Kyun Woo),이화성(Hwa-Sung Lee),이문홍(Moon-Hong Lee) 대한정형외과학회 1999 대한정형외과학회지 Vol.34 No.4

경남지구(慶南地區)의 스카른형(型) 광상(鑛床)의 성인(成因)과 스카른광물(鑛物)에 관(關)한 연구(硏究)

우영균,이민성,박희인,Woo, Young Kyun,Lee, Min Sung,Park, Hee-In 대한자원환경지질학회 1982 자원환경지질 Vol.15 No.1

Many skarn type iron ore deposits are distributed in Kimhae-Mulgeum area of Gyeongnam Province. Integrated field, mineralogic, geochemical and fluid inclusion studies were undertaken to illustrate the character and origin of the ores in this area. The iron ore deposits in this area are NS or NNE trending fracture filling magnetite veins which are developed in andesitic rocks near the contact with late Cretaceous micrographic granite bodies. Symmetrically zoned skarns are commonly developed in the magnetite veins of this area. Zoning of skarn from center to margin of the vein are as follows; garnet quartz skarn-epidote skarn-epidote orthoclase skarn-altered andesitic rocks. Major ore mineral is magnetite and small amount of hematite, pyrite, pyrrhotite, chalcopyrite and sphalerite are associated. Vein paragenesis reveals four depositional stages; 1) skarn stage, 2) iron sulfide and oxide stage, 3) skarn stage, 4) sulfide stage Minute halite-bearing polyphase inclusions and liquid inclusions are contained in quartz. Filling temperatures range from $257^{\circ}$ to $370^{\circ}C$.

충남(忠南) 예산지구(禮山地區) 활석광상(滑石鑛床)의 성인(成因)에 관(關)한 연구(硏究)

우영균,최석원,박기화,Woo, Young-Kyun,Choi, Suck-Won,Park, Ki-Hwa 대한자원환경지질학회 1991 자원환경지질 Vol.24 No.4

Field and microscopic evidence, XRD,EPMA and chemical data suggest that parent rock of talc ore deposits of Yesan district was originated from ultramafic igneous rock. Parent rock can be divided into serpentinized dunite, serpentinized peridotite, metagabbro, amphibolite and hornblende schist. The ore deposits are highly sheared, and show many evidences of hydrothermal alteration and metamorphism at the greenschist and albite-epidote amphibolite facies. The process of steatitization is variable depending upon the composition, and the degree of alteration and metamorphism of the parent rocks. Steatitization can be divided into two processes with or without serpentinization. The parent rocks with serpentinization are serpentinized dunite, serpentinized peridotite and metagabbro, showing the following alteration process; olivine ${\rightarrow}$ serpentine${\rightarrow}$ talc. The rocks without serpentinization are amphibolite and hornblende schist showing the following sequence; hornblende${\rightarrow}$ chlorite${\rightarrow}$ talc. Formation of talc deposits is summarized as following six stages; I) Intrusion of ultramafic rocks, 2) autometamorphism, 3) metamorphism at greenschist and albite-epidote-amphibolite facies, 4) brittle deformation, 5) hydrothermal alteration, 6) purification of low-grade talc by late dyke intrusion.

척추 전이암의 수술적 치료

우영균(Young Kyun Woo),이승구(Seung Koo Rhee),김형민(Hyoung Min Kim),강용구(Yong Koo Kang),송석환(Suk Whan Song),박원종(Won Jong Bahk),강종후(Chong Hoo Kang),강승범(Seung Beom Kang) 대한정형외과학회 1993 대한정형외과학회지 Vol.28 No.5