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      • KCI등재후보

        Empirical likelihood for nonparametric regression models with spatial autoregressive errors

        Yinghua Li,Yongsong Qin,Li Yuan 한국통계학회 2021 Journal of the Korean Statistical Society Vol.50 No.2

        In this paper, we propose to use the empirical likelihood (EL) method to construct confidence regions for nonparametric regression models with spatial autoregressive errors. It is shown that the EL statistics for the related parameters asymptotically have chi-squared distributions, which are used to construct confidence regions for the parameters. Results from simulation study and real data analysis are also presented.

      • KCI등재

        Spontaneous Peripheral Ameloblastic Odontoma in a Male Sprague-Dawley Rat

        Yinghua Li,Han-Ik Bae,Hak-Soo Kim,Min-Soo Kang,Bo-Ho Gong,Won-Hee Jung,Sranna Lee,Jin-Sook Bae,Kap-Ho Kim,Si-Whan Song,Jae-Hyun Lee,Boo-Hyon Kang 한국독성학회 2017 Toxicological Research Vol.33 No.2

        Peripheral ameloblastic odontoma is a rare variant of odontogenic tumor occurring in the extraosseous region. The present report describes a spontaneous tumor in male Sprague-Dawley (SD) rats. The clinically confirmed nodule in the right mandibular region was first observed when the rat was 42 weeks and remained until the terminal sacrifice date when the animal was 48 weeks of age. At necropsy, a well demarcated nodule, approximately 2.5 × 2.0 × 2.0 cm, protruded from the ventral area of the right mandible. The nodule was not attached to mandibular bone and was not continuous with the normal teeth. Histopathologically, the tumor was characterized by the simultaneous occurrence of an ameloblastomatous component and composite odontoma-like elements within the same tumor. The epithelial portion formed islands or cords resembling the follicle or plexiform pattern typical of ameloblastoma and was surrounded by mesenchymal tissue. Formation of eosinophilic and basophilic hard tissue matrix (dentin and enamel) resembling odontoma was observed in the center of the tumor. Mitotic figures were rare, and areas of cystic degeneration were present. Immunohistochemically, the epithelial component was positive for cytokeratin AE1/AE3 (CK AE1/AE3), and the mesenchymal component and odontoblast-like cells were positive for vimentin, in the same manner as in normal teeth. On the basis of these findings, the tumor was diagnosed as a peripheral ameloblastic odontoma in an extraosseous mandibular region in a SD rat. In the present study, we report the uncommon spontaneous peripheral ameloblastic odontoma in the SD rat. We also discuss here the morphological characteristics, origin, histochemical, and immunohistochemical features for the diagnosis of this tumor.

      • SCOPUSKCI등재

        Spontaneous Peripheral Ameloblastic Odontoma in a Male Sprague-Dawley Rat

        Li, Yinghua,Bae, Han-Ik,Kim, Hak-Soo,Kang, Min-Soo,Gong, Bo-Ho,Jung, Won-Hee,Lee, Sranna,Bae, Jin-Sook,Kim, Kap-Ho,Song, Si-Whan,Lee, Jae-Hyun,Kang, Boo-Hyon Korean Society of ToxicologyKorea Environmental Mu 2017 Toxicological Research Vol.33 No.2

        Peripheral ameloblastic odontoma is a rare variant of odontogenic tumor occurring in the extraosseous region. The present report describes a spontaneous tumor in male Sprague-Dawley (SD) rats. The clinically confirmed nodule in the right mandibular region was first observed when the rat was 42 weeks and remained until the terminal sacrifice date when the animal was 48 weeks of age. At necropsy, a well demarcated nodule, approximately $2.5{\times}2.0{\times}2.0cm$, protruded from the ventral area of the right mandible. The nodule was not attached to mandibular bone and was not continuous with the normal teeth. Histopathologically, the tumor was characterized by the simultaneous occurrence of an ameloblastomatous component and composite odontoma-like elements within the same tumor. The epithelial portion formed islands or cords resembling the follicle or plexiform pattern typical of ameloblastoma and was surrounded by mesenchymal tissue. Formation of eosinophilic and basophilic hard tissue matrix (dentin and enamel) resembling odontoma was observed in the center of the tumor. Mitotic figures were rare, and areas of cystic degeneration were present. Immunohistochemically, the epithelial component was positive for cytokeratin AE1/AE3 (CK AE1/AE3), and the mesenchymal component and odontoblast-like cells were positive for vimentin, in the same manner as in normal teeth. On the basis of these findings, the tumor was diagnosed as a peripheral ameloblastic odontoma in an extraosseous mandibular region in a SD rat. In the present study, we report the uncommon spontaneous peripheral ameloblastic odontoma in the SD rat. We also discuss here the morphological characteristics, origin, histochemical, and immunohistochemical features for the diagnosis of this tumor.

      • Empirical likelihood for spatial dynamic panel data models

        Li Yinghua,Qin Yongsong 한국통계학회 2022 Journal of the Korean Statistical Society Vol.51 No.2

        Spatial dynamic panel data (SDPD) models have received great attention in economics in recent 10 years. Existing approaches for the estimation and test of SDPD models are quasi-maximum likelihood (QML) approach and generalized method of moments (GMM). In this article, we introduce the empirical likelihood (EL) method to the statistical inference for SDPD models. The EL ratio statistics are constructed for the parameters of spatial dynamic panel data models. It is shown that the limiting distributions of the empirical likelihood ratio statistics are chi-squared distributions, which are used to construct confdence regions for the parameters of the models. Simulation results show that the EL based confdence regions outperform the normal approximation based confdence regions.

      • SCIESCOPUS

        Statistics and probability analysis of vehicle overloads on a rigid frame bridge from long-term monitored strains

        Li, Yinghua,Tang, Liqun,Liu, Zejia,Liu, Yiping Techno-Press 2012 Smart Structures and Systems, An International Jou Vol.9 No.3

        It is well known that overloaded vehicles may cause severe damages to bridges, and how to estimate and evaluate the status of the overloaded vehicles passing through bridges become a challenging problem. Therefore, based on the monitored strain data from a structural health monitoring system (SHM) installed on a bridge, a method is recommended to identify and analyze the probability of overloaded vehicles. Overloaded vehicle loads can cause abnormity in the monitored strains, though the abnormal strains may be small in a concrete continuous rigid frame bridge. Firstly, the abnormal strains are identified from the abundant strains in time sequence by taking the advantage of wavelet transform in abnormal signal identification; secondly, the abnormal strains induced by heavy vehicles are picked up by the comparison between the identified abnormal strains and the strain threshold gotten by finite element analysis of the normal heavy vehicle; finally, according to the determined abnormal strains induced by overloaded vehicles, the statistics of the overloaded vehicles passing through the bridge are summarized and the whole probability of the overloaded vehicles is analyzed. The research shows the feasibility of using the monitored strains from a long-term SHM to identify the information of overloaded vehicles passing through a bridge, which can help the traffic department to master the heavy truck information and do the damage analysis of bridges further.

      • KCI등재

        Optimization of Medium Components for Plasmid Production by Recombinant E. coli DH5α pUK21CMVβ1.2

        Yinghua Lu,Shuzhen Zheng,Karl Friehs,Ning He,Xu Deng,Qingbiao Li,Zheng He,Chenyun Xu 한국생물공학회 2007 Biotechnology and Bioprocess Engineering Vol.12 No.3

        In this study we investigated the effects of carbon and nitrogen sources, and the carbon to nitrogen ratio (C:N) of growth medium on the production of plasmid DNA by pUK21CMVβ1.2 harbouring recombinant E. coli. The results indicated that sucrose and casein peptone were the most suitable carbon and nitrogen sources, respectively, for plasmid production, and the plasmid concentration was significantly influenced by the C:N ratio. A Box-Behnken design and surface response methodology were employed to formulate the optimal medium. In the optimized medium, a plasmid concentration of 51.80 mg/L and a plasmid selectivity of 23.49 mg/g were achieved after 24 h of incubation. These values were approximately 3.5 and 1.7 times higher, respectively, than those obtained on the original LB medium.

      • KCI등재

        Synthesis of Cd1-xZnxS/K4Nb6O17 Composite and its Photocatalytic Activity for Hydrogen Production

        Yinghua Liang,Meiyi Shao,Li Liu,Jinshan Hu,Wenquan Cui 대한화학회 2014 Bulletin of the Korean Chemical Society Vol.35 No.4

        Cd1-xZnxS-sensitized K4Nb6O17 composite photocatalysts (designated Cd1-xZnxS/K4Nb6O17) were prepared via a simple deposition-precipitation method. The samples were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive X-ray spectrometry (EDS), N2 sorption, ultraviolet–visible light diffuse reflectance spectroscopy (UV–Vis DRS), photoluminescence measurements (PL), and X-ray photoelectron spectroscopy (XPS). The Cd0.8Zn0.2S particles were scattered on the surface of K4Nb6O17, and had a relatively uniform size distribution around 50 nm. The absorption edge of K4Nb6O17 was shifted to the visible light region and the recombination of photo-generated electrons and holes suppressed after Cd0.8Zn0.2S loading. The Cd0.8Zn0.2S(25 wt %)/K4Nb6O17 composite possessed the highest photocatalytic activity for hydrogen production under visible light irradiation, evolving 8.278 mmol/g in 3 h. Recyclability tests were performed, and the composite photocatalysts were found to be fairly stable. The mechanism of charge separation between the photogenerated electrons and holes at the Cd0.8Zn0.2S/K4Nb6O17 composite was discussed.

      • A Case Study of the Satisfaction of College Students on Blackboard System

        Li Zheng,Yinghua Niu 보안공학연구지원센터 2016 International Journal of Multimedia and Ubiquitous Vol.11 No.4

        Taking the Business College of Beijing Union University as an example, a survey and an in-depth study on the application of Blackboard system for College students about their learning attitudes, experiences, expectations and satisfaction was carried out. The study aims at 5 parts: the safety and stability of system platform, the aesthetics of interface design and accuracy of navigation, the richness and update of resources, the interaction and cooperation between the teachers and students, and the monitoring timely in the whole learning process. Based on the 5 aspects, the views and satisfaction of the respondents’ Blackboard system application were investigated and analyzed between different genders, different learning attitudes, different grades and different majors. The results showed that, in general, the students were satisfied with the overall situation of the construction and application of the Blackboard. However, for some of the 5 parts, significant differences were shown between different gender, different learning attitudes, different grades and different majors. The results of the survey provide a certain reference and some suggestions for teachers to further improve the Blackboard-based courses construction and management, and finally enhance students' satisfaction.

      • KCI등재

        Valveless Piezoelectric Micropump of Parallel Double Chambers

        Li Guo,Weiping Yan,Yinghua Xu,Yiru Chen 한국정밀공학회 2012 International Journal of Precision Engineering and Vol. No.

        The driving performance of the piezoelectric actuator was simulated by ANSYS software, and the relationship between structure parameters and center displacement/frequency of piezoelectric actuator were obtained. The nozzle/diffuser pipes’structure parameters were optimized according to the results of ANSYS numerical simulation, and flow characteristic parameters such as flow rate and pressure distribution in the pipe were researched. The chamber was manufactured on glass, and nozzle/diffuser pipes were fabricated on <100> silicon by selective-wet etch using MEMS technology. These two components were glued with piezoelectric actuator together to form micropumps with single chamber and micropumps with parallel double chambers. The flow rates of micropumps in different conditions were measured by test system. Finally, a comparison between the test results of micropump with double chambers and that of the single chamber micropump is given.

      • KCI등재

        A Comprehensive Review of Lipidomics and Its Application to Assess Food Obtained from Farm Animals

        Yinghua Song,Changyun Cai,Yingzi Song,Xue Sun,Baoxiu Liu,Peng Xue,Mingxia Zhu,Wenqiong Chai,Yonghui Wang,Changfa Wang,Mengmeng Li 한국축산식품학회 2022 한국축산식품학회지 Vol.42 No.1

        Lipids are one of the major macronutrients essential for adequate growth and maintenance of human health. Their structure is not only complex but also diverse, which makes systematic and holistic analyses challenging; consequently, little is known regarding the relationship between phenotype and mechanism of action. In recent years, rapid advancements have been made in the fields of lipidomics and bioinformatics. In comparison with traditional approaches, mass spectrometry-based lipidomics can rapidly identify as well as quantify >1,000 lipid species at the same time, facilitating comprehensive, robust analyses of lipids in tissues, cells, and body fluids. Accordingly, lipidomics is now being widely applied in various fields, particularly food and nutrition science. In this review, we discuss lipid classification, extraction techniques, and detection and analysis using lipidomics. We also cover how lipidomics is being used to assess food obtained from livestock and poultry. The information included herein should serve as a reference to determine how to characterize lipids in animal food samples, enhancing our understanding of the application of lipidomics in the field in animal husbandry.

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