Comparative Patterns of Physiological Responses to Cold Resistance of Zanthoxylum bungeanum Maxim

Shengyuan Liu,Xiumei Liu,Xinying Han,Huatian Wang,Ping Xu,Chunmei Zhang 한국원예학회 2023 원예과학기술지 Vol.41 No.5

Eucommia ulmoides Bark Protects Against Renal Injury in Cadmium-Challenged Rats

Erwei Liu,Lifeng Han,Jialong Wang,Wei He,Haihua Shang,Xiumei Gao,Tao Wang 한국식품영양과학회 2012 Journal of medicinal food Vol.15 No.3

Eucommia ulmoides Oliver is a perennial woody plant distributed widely in China. To characterize some major compounds in E. ulmoides bark extract, six compounds were identified via high-performance liquid chromatography qualitative analysis. E. ulmoides bark extract protects against cadmium-induced oxidative damage in rat kidneys. Two compounds of E. ulmoides bark extract, geniposide and genipin, which were identified both in serum and in kidney tissue, showed inhibitory effects on nitric oxide production. This study provides biological evidence supporting the usefulness of E. ulmoides bark against cadmium-induced toxic oxidative stress in rat kidney tissue.

Population Genetic Structure of Liza affinis (Eastern Keelback Mullet), Reveals High Gene Flow Inferred from Microsatellite Analysis

Lu Liu,Xiumei Zhang,Dianrong Sun,Tianxiang Gao,Na Song 한국해양과학기술원 2019 Ocean science journal Vol.54 No.2

The population genetic studies of marine fishes usually show complex patterns of genetic differentiation which were influenced by both historical process and contemporary gene flow. Genetic structure of eight different populations for eastern keelback mullet, Liza affinis, collected from the coast along eastern and southern China, was examined using six microsatellite loci. We found strong genetic similarities among most of the samples except the Dongguan population and most microsatellite variation was found within populations. All loci were characterized by high genetic variability with expected heterozygosities ranging from 0.871 to 0.928. The Bayesian cluster analysis of the microsatellite data detected four genetic groups with no relation to geographic areas. The bottleneck results also showed no significant values. Based on these data we postulated that complex marine currents and larval dispersal shaped the genetic structured of studied populations. The present study illustrated the importance of understanding the biological significance of genetic differentiation when using molecular data in identifying units for management and protection.

A mixed method study of ethical issues in classroom assessment in Chinese higher education

Fan Xumei,Liu Xiumei,Johnson Robert L. 서울대학교 교육연구소 2020 Asia Pacific Education Review Vol.21 No.2

The purpose of this study was to explore Chinese university professors’ decisions about ethical issues in classroom assessment. A survey with ffteen scenarios that describe professors’ thoughts about ethics in assessment practices was administrated to 555 professors from 143 colleges and universities in 29 provinces in China. The results of the quantitative analysis indicated that professors’ interest in professional development related to classroom assessment, and their dispositions were signifcantly associated with their agreement with experts in the feld of classroom assessment. Professors’ gender, highest degree, professional rank, and years of teaching experience did not signifcantly predict their agreement. The qualitative analysis revealed that maintaining fair assessment vs being caring to students and asserting professors’ rights vs abiding by university policy were the crucial aspects for professors to consider in classroom assessment. Findings of the study could help educators identify ethical issues in assessment, develop guidelines to ensure fair assessment, and incorporate diferentiated strategies in professional development workshops in higher education.

Optimization of optical modulation in amorphous WO3 thin films

Jiangbin Su,Xiumei Zhu,Longlong Chen,Yu Liu,Hao Qi,Zuming He,Bin Tang 대한금속·재료학회 2024 ELECTRONIC MATERIALS LETTERS Vol.20 No.2

WO 3 thin fi lms were prepared on indium-tin oxide (ITO) glass substrates at diff erent substrate temperature by radiofrequency magnetron sputtering. Then the fi lms were soaked in fi ve organic solvents of acetone, ethanol, cyclohexane,acetonitrile and ethyl acetate for 48 h, respectively. The changes in the microstructure, surface morphology and electrochromic(EC) properties of WO 3 thin fi lms before and after the immersion treatment were systematically studied. It wasfound that after soaking in ethanol, the optical modulation of amorphous WO 3 thin fi lms deposited at room temperatureincreased from 50 to 85%, showing excellent EC performance. Moreover, the immersion treatment in ethanol is also helpfulfor improving the EC properties of amorphous WO 3 thin fi lms prepared at elevated substrate temperature. However,after immersion in the other organic solvents, the optical modulation of WO 3 thin fi lms increased less (for acetone: 77%)or even decreased signifi cantly (for cyclohexane, acetonitrile and ethyl acetate: 31%, 30% and 35%, respectively). In addition,the immersion treatment in ethanol cannot improve the optical modulation of crystalline WO 3 thin fi lms prepared at600 °C, which dropped from 58 to 40%. The authors believe that this is mainly related to the diff erent dredging eff ects ofvarious organic solvents on the transport channels of Li-ions and electrons in WO 3 thin fi lms. Therefore, this work providesa new approach for the optimization of EC performance of amorphous WO 3 thin fi lms.

Effects of Zeolites on Thermal Stability of Poly(vinyl chloride)

Jiayou Xu,Qinghua Liang,Xiumei Xian,Kaidan Li,Jie Liu 한국고분자학회 2015 폴리머 Vol.39 No.1

The effects of zeolite on the thermal stability of poly(vinyl chloride) (PVC) were investigated by the static thermal stability test, pyrolysis experiment and ultraviolet spectrum. The results showed that the porous zeolite could absorb hydrogen chloride (HCl), which suppressed the catalysis of HCl on thermal degradation of PVC, thus improved the thermal stability of PVC. The oxidizing acid which was loaded on zeolite had oxidated on the double bond that formed during the dehydrochlorination of PVC. This process could prohibit the growth of the conjugated polyene and improved the color of PVC. Hence, zeolite might be possible to come up with a high performance thermal stabilizer.

Comparisons and Correlations of Phenolic Profiles and Anti-oxidant Activities of Seventeen Varieties of Pineapple

Liqing Du,Guangming Sun,Xiumei Zhang,Yuge Liu,Witoon Prinyawiwatkul,Zhimin Xu,Yixiao Shen 한국식품과학회 2016 Food Science and Biotechnology Vol.25 No.2

Major phenolic, β-carotene, and ascorbic acid (AA) contents in 17 pineapple varieties were quantified and compared. Anti-oxidant activities were evaluated using 2,2-Diphenyl-l-picrylhydrazyl (DPPH), 2,2'-Azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS), ferric reducing anti-oxidant power (FRAP), and metal chelating capacity (MCC) assays. MD-2 exhibited the highest AA and total phenolic (TP) contents and DPPH and ABTS assay results, but was lower in β-carotene contents. Ripley had the highest total flavonoid (TF) content with a low AA content. Comte de Pairs exhibited the highest MCC and the lowest FRAP values. TP contents and both DPPH and ABTS activities, FRAP values and both AA contents and DPPH activities, and TF contents and ABTS activities were positively correlated. MD-2 exhibited the greatest diversity of phenolics and highest anti-oxidant activities in all assays. Information included herein can be useful for development of pineapple-based food products containing high levels of health promoting anti-oxidants.

Ginsenoside Rg3 ameliorates myocardial glucose metabolism and insulin resistance via activating the AMPK signaling pathway

Jingyu Ni,Zhihao Liu,Miaomiao Jiang,Lan Li,Jie Deng,Xiaodan Wang,Jing Su,Yan Zhu,Feng He,Jingyuan Mao,Xiumei Gao,Guanwei Fan 고려인삼학회 2022 Journal of Ginseng Research Vol.46 No.2

Background: Ginsenoside Rg3 is one of the main active ingredients in ginseng. Here, we aimed to confirm its protective effect on the heart function in transverse aortic coarctation (TAC)-induced heart failure mice and explore the potential molecular mechanisms involved. Methods: The effects of ginsenoside Rg3 on heart and mitochondrial function were investigated by treating TAC-induced heart failure in mice. The mechanism of ginsenoside Rg3 for improving heart and mitochondrial function in mice with heart failure was predicted through integrative analysis of the proteome and plasma metabolome. Glucose uptake and myocardial insulin sensitivity were evaluated using micro-positron emission tomography. The effect of ginsenoside Rg3 on myocardial insulin sensitivity was clarified by combining in vivo animal experiments and in vitro cell experiments. Results: Treatment of TAC-induced mouse models with ginsenoside Rg3 significantly improved heart function and protected mitochondrial structure and function. Fusion of metabolomics, proteomics, and targeted metabolomics data showed that Rg3 regulated the glycolysis process, and Rg3 not only regulated glucose uptake but also improve myocardial insulin resistance. The molecular mechanism of ginsenoside Rg3 regulation of glucose metabolism was determined by exploring the interaction pathways of AMPK, insulin resistance, and glucose metabolism. The effect of ginsenoside Rg3 on the promotion of glucose uptake in IR-H9c2 cells by AMPK activation was dependent on the insulin signaling pathway. Conclusions: Ginsenoside Rg3 modulates glucose metabolism and significantly ameliorates insulin resistance through activation of the AMPK pathway.

THE SUITABILITY OF MITOCHONDRIAL AND MICROSATELLITE DNA AS GENETIC TAGS TO ASSESS STOCK ENHANCEMENT OF Portunus trituberculatus

Shengyong Xu,Shanshan Cai,Xiumei Zhang,Ming Liu,Na Song,Jun Wang,Tianxiang Gao 한국수산과학회 양식분과 2015 한국수산과학회 양식분과 학술대회 Vol.2015 No.5

Didymin Alleviates Cerebral Ischemia-Reperfusion Injury by Activating the PPAR Signaling Pathway

Qiang Li,Hongting Zhang,Xiumei Liu 연세대학교의과대학 2022 Yonsei medical journal Vol.63 No.10

Purpose: Cerebral ischemia-reperfusion (IR) injury is a severe secondary injury induced by reperfusion after stroke. Didymin has been reported to have a protective effect on intracerebral hemorrhage. However, the underlying mechanism of didymin on regu lating cerebral IR injury remains largely unknown. Materials and Methods: A rat cerebral IR model and oxygen-glucose deprivation/reperfusion (OGD/R) model in PC12 cells were established. Hematoxylin and eosin (H&E) was used to detect the pathological changes in brain tissues, and TUNEL staining was performed to detect apoptosis of brain tissues. MTT and flow cytometry were used to measure the viability and apoptosis of PC12 cells. QRT-PCR and western blot were used to detect inflammation cytokines in PC12 cells. Western blot was used to measure the expression of PPAR-γ, RXRA, Bax, c-caspase-3, and Bcl-2. Results: Didymin pretreatment decreased apoptotic rates, reduced levels of Bax and c-caspase-3, and increased Bcl-2 level in vivo and in vitro. Additionally, didymin pretreatment increased viability and decreased the inflammation levels [interleukin (IL)-1β, IL-6, tumor necrosis factor (TNF)-α, and monocyte chemotactic protein (MCP)-1] of OGD/R treated PC12 cells. Moreover, did ymin activated the peroxisome proliferator-activated receptors (PPAR) signaling pathway and increased the expression of PPAR-γ and RXRA in OGD/R treated PC12 cells. Inhibition of PPAR-γ eliminated the protective effect of didymin on OGD/R treated cells. Conclusion: Didymin protected neuron cells against IR injury in vitro and in vivo by activation of the PPAR pathway. Didymin may be a candidate drug for IR treatment.