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      • KCI등재

        Post-Process Modification of CeOx/C-Supported PtCu Thin Film Catalyst and Its Catalytic Activity for Hydrogen Evolution Reaction

        Yumeng Zhao,Bin Yang,Xinyu Hao,Zhijing Zhao 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2015 NANO Vol.10 No.6

        CeOx/C supported PtCu thin film catalysts were prepared by ion beam sputtering (IBS) and subsequently annealed at 400℃ under vacuum environment and electrochemically dealloyed. Scanning transmission electronic microscope (STEM) and atomic force microscope (AFM) characterizations show that the surface of post-processed catalyst presents nanoporous structure and has a high root mean square roughness ( RMS=13.9 nm). Electrochemical measurements indicate that the post-processed PtCu – CeOx/C catalyst shows higher catalytic activity towards hydrogen evolution reaction than pure Pt/C. While inductively coupled plasma atomic emission spectroscopy (ICP-AES) analysis displays that the platinum (Pt) loading of the post-processed PtCu – CeOx/C is 0.1192 mg/cm2, decreasing by 20% compare to pure Pt/C (0.1490 mg/cm2). X-ray photoelectron spectroscopy (XPS) analysis confirms that the surface of post-processed PtCu – CeOx/C enrich Pt and analyzes the chemical valence of Pt element using depth profiling technology. It can be inferred that the enhancement in catalytic property is attributed to the combined action between geometric structure effect and electronic modification effect of Pt atoms from CeOx support.

      • Research Optimization of the Management of New Product Development Projects: the case of Lenovo

        Chen Xi,Wang Xinyu,Li Hao 한중경제문화학회 2024 한중경제문화연구 Vol.25 No.-

        In recent years, electronic products have played an increasingly important role in modern society and have penetrated into people’s life and work. With the continuous development of technology and the increasing demand for convenience and innovation, the functions and performance of electronic products continue to improve. However, the intensification of market competition and the rapid advancement of technological progress have brought many challenges and opportunities to the field of electronic products. This paper takes the new product development project management process of Lenovo Company as the research object, adopts investigation analysis method, literature analysis method and project management theory and gateway development management theory to deeply analyze the existing problems in the new product development project management of Lenovo Company, such as: The new product development cycle is long, the new product development cost is over budget, the new product development project organization and coordination ability is weak, and the project monitoring and feedback are not timely. The causes of these problems are analyzed. In view of the existing problems, this paper makes an in-depth study of the relevant theories of project management and new product development, and puts forward an optimization scheme suitable for the improvement of the new product development project management of Lenovo Company. It means adopting agile development scheme, establishing project development cost control point, optimizing organizational structure, and establishing perfect project management supervision and feedback mechanism. Finally, based on the current situation of Lenovo ‘s new product development, this paper proposes the guarantee measures for the smooth implementation of the new product development project management optimization plan, namely, talent guarantee, development and innovation awareness, risk control awareness, and management awareness in strengthening cultural construction, so as to ensure the smooth implementation of new product development project management.

      • Moving Target Detection and Tracking in Complex Background

        Gu Bo,Hu Hao,Ren Yan,Liu Xinyu 보안공학연구지원센터 2015 International Journal of Smart Home Vol.9 No.9

        The influence of environment changing, e.g. background beam change, trees waggle, and rain or snow day brings More difficult for moving target detecting. A background dynamic generation algorithm is presented in the paper, and the background dynamic generation algorithm is used to dynamically construct background image, the impact of the environment change is reduced in a certain extent for the moving target detection. Secondly, the background difference method is used to detect the moving target, when the moving target exists, the direction and the coordinate of the moving target is determined according to the result of continuous 2 frame images subtract the background. Finally, an algorithm for calculating the rotation angle of the pan/tilt/zoom is presented, the horizontal rotation angle and the vertical rotation angle of the pan/tilt/zoom is calculated according to the pan/tilt/zoom rotation angle algorithm, and the moving target detection and automatic tracking function is realized.

      • KCI등재

        Thermodynamic analysis of hybrid two-stage CO2 mechanical compression–ejector cooling cycle

        Ierin Volodymyr,Chen Guangming,Hao Xinyue,Volovyk Oleksii 대한설비공학회 2023 International Journal of Air-Conditioning and Refr Vol.31 No.1

        In the present study, the main results of thermodynamic analysis of the hybrid two-stage carbon dioxide (CO2) transcritical mechanical compression–ejector cooling cycle using R245ca are provided. In the proposed cycle, an increase in the energy efficiency of a mechanical compression refrigeration machine (MCRM) is provided by additional supercooling of CO2 after the gas cooler due to the use of cold obtained in an ejector cooling machine (ECM). The ECM uses part of the superheated vapor heat after the high-pressure compressor and the intermediate pressure heat after the low-pressure compressor. This solution provides intermediate cooling of CO2 vapor without using an external cooling medium. The proposed method of computation makes it possible to determine the optimal parameters of the hybrid cooling cycle for the design conditions, ensuring the maximum possible MCRM efficiency. At the same time, the method considers the need to determine the optimal gas cooler pressure – a parameter that has a significant impact on efficiency growth. The effect of the intermediate pressure is extremely insignificant and is defined as the geometric mean value of the product of the gas cooler and evaporator pressures. The results show an increase in efficiency of the two-stage CO2 MCRM by up to 31.6% at high temperatures of the environment. In addition, as a result of the exergy analysis, components have been identified, the improvement of which can lead to an additional increase in the efficiency of the entire system. As follows from the data obtained, the greatest attention should be paid to improving the ejector and reducing throttle losses in the CO2 cycle. In the present study, the main results of thermodynamic analysis of the hybrid two-stage carbon dioxide (CO 2 ) transcritical mechanical compression–ejector cooling cycle using R245ca are provided. In the proposed cycle, an increase in the energy efficiency of a mechanical compression refrigeration machine (MCRM) is provided by additional supercooling of CO 2 after the gas cooler due to the use of cold obtained in an ejector cooling machine (ECM). The ECM uses part of the superheated vapor heat after the high-pressure compressor and the intermediate pressure heat after the low-pressure compressor. This solution provides intermediate cooling of CO 2 vapor without using an external cooling medium. The proposed method of computation makes it possible to determine the optimal parameters of the hybrid cooling cycle for the design conditions, ensuring the maximum possible MCRM efficiency. At the same time, the method considers the need to determine the optimal gas cooler pressure – a parameter that has a significant impact on efficiency growth. The effect of the intermediate pressure is extremely insignificant and is defined as the geometric mean value of the product of the gas cooler and evaporator pressures. The results show an increase in efficiency of the two-stage CO 2 MCRM by up to 31.6% at high temperatures of the environment. In addition, as a result of the exergy analysis, components have been identified, the improvement of which can lead to an additional increase in the efficiency of the entire system. As follows from the data obtained, the greatest attention should be paid to improving the ejector and reducing throttle losses in the CO 2 cycle.

      • KCI등재

        InP/InGaAs/InP DHBT structures with N+ doped composite collectors grown by gas source molecular beam epitaxy

        Anhuai Xu,Likun Ai,Hao Sun,Ming Qi,Shubing Su,Xinyu Liu,Xunchun Liu,He Qian 한양대학교 세라믹연구소 2006 Journal of Ceramic Processing Research Vol.7 No.2

        InP/InGaAs/InP double heterojunction bipolar transistor (DHBT) structural materials with N+ doped composite collectors were designed and grown successfully by gas source molecular beam epitaxy (GSMBE). High-quality lattice-matched InGaAs/ InP hetero epi-layers were obtained through optimizing the growth conditions. The performance of InP/InGaAs/InP DHBTs with a thin heavily doped n-type InP layer at the base-collector interface was also demonstrated. It was shown that the energy barrier between the base and collector was effectively eliminated by a 3 nm thick n-type InP layer with ND=3×1019 cm−3. The DHBT devices with an emitter size of 2×12 μm2 showed fT > 80 GHz and BVceo > 9 V, which can be comparable to the results reported for DHBTs with a graded layer between the base and collector.

      • KCI등재

        Preparation of decorative slag glass-ceramics and research on the solidification of heavy metals

        Yang Tang,Xiaodong Hao,Zhenxiang Fang,Xinyu Bai,Guangyu Wang,Hongxia Zhang,Leibo Deng,Hua Chen,Ming Zhao,Yongsheng Du 한양대학교 청정에너지연구소 2023 Journal of Ceramic Processing Research Vol.24 No.1

        Glass-ceramics with different CuO additions were prepared with Fe2O3 and Cr2O3 as composite nucleating agents, rare earthcontainingblast furnace slag (REBFS) as the main raw material. The existence state and stability of heavy metals Cu, Mn andCr in glass-ceramics were investigated. The results showed that Cr ions contributed to the generation of spinel phase, whileCu ions and Mn ions can enter the spinel crystal and exist stably, which indicated that there was a synergistic solidificationof Cu, Mn and Cr. The depolymerization effect of the copper ions contributed to the transformation of the crystal morphologyfrom dendrites to spherulites. Moreover, the increase in CuO contents promoted glass-ceramics from green to copper red. Based on the leaching experimental data analysis of heavy metals in glass-ceramics, the leaching concentration of heavy metalsCu, Cr and Mn were much lower than the standard leaching toxicity limit of hazardous waste (GB5085.3–2007, China). Theresults showed that the conversion of REBFS into environmentally friendly glass-ceramics can realize solid waste resourceutilization.

      • KCI등재후보

        Ginsenoside Rg1 alleviates vascular remodeling in hypoxia-induced pulmonary hypertension mice through the calpain-1/ STAT3 signaling pathway

        Chenyang Ran,Meili Lu,Fang Zhao,Yi Hao,Xinyu Guo,Yunhan Li,Yuhong Su,Hongxin Wang 고려인삼학회 2024 Journal of Ginseng Research Vol.48 No.4

        Background: Hypoxic pulmonary hypertension (HPH) is the main pathological change in vascular remodeling, acomplex cardiopulmonary disease caused by hypoxia. Some research results have shown that ginsenoside Rg1(Rg1) can improve vascular remodeling, but the effect and mechanism of Rg1 on hypoxia-induced pulmonaryhypertension are not clear. The purpose of this study was to discuss the potential mechanism of action of Rg1 onHPH. Methods: C57BL/6 mice, calpain-1 knockout mice and Pulmonary artery smooth muscle cells (PASMCs) wereexposed to a low oxygen environment with or without different treatments. The effect of Rg1 and calpain-1silencing on inflammation, fibrosis, proliferation and the protein expression levels of calpain-1, STAT3 and p-STAT3 were determined at the animal and cellular levels. Results: At the mouse and cellular levels, hypoxia promotes inflammation, fibrosis, and cell proliferation, and theexpression of calpain-1 and p-STAT3 is also increased. Ginsenoside Rg1 administration and calpain-1 knockdown,MDL-28170, and HY-13818 treatment showed protective effects on hypoxia-induced inflammation,fibrosis, and cell proliferation, which may be associated with the downregulation of calpain-1 and p-STAT3expression in mice and cells. In addition, overexpression of calpain 1 increased p-STAT3 expression, acceleratingthe onset of inflammation, fibrosis and cell proliferation in hypoxic PASMCs. Conclusion: Ginsenoside Rg1 may ameliorate hypoxia-induced pulmonary vascular remodeling by suppressingthe calpain-1/STAT3 signaling pathway.

      • KCI등재

        Neutrophil extracellular traps mediate the crosstalk between plaque microenvironment and unstable carotid plaque formation

        Cao Yu,Chen Minghui,Jiao Xinyu,Li Shuijie,Wang Dong,Zhan Yongxuan,Li Jiaju,Hao Zhongfei,Li Qingbin,Liu Yang,Feng Yan,Li Ruiyan,Wang Hongjun,Liu Mingli,Fu Qiang,Li Yongli 생화학분자생물학회 2024 Experimental and molecular medicine Vol.56 No.-

        The development of unstable carotid atherosclerotic plaques is associated with the induction of neutrophil extracellular traps (NETs) via the activation of diverse inflammatory mediators in the circulating bloodstream. However, the underlying mechanisms through which NETs influence the microenvironment of atherosclerotic plaques and contribute to the development of unstable carotid plaques remain largely elusive. The objective of this study was to elucidate the role of myeloid differentiation protein 1 (MD-1, LY86)-induced NETs underlying the crosstalk between unstable plaque formation and the plaque microenvironment. We employed bioinformatics analysis to identify key genes associated with carotid-unstable plaque, followed by comprehensive validation using various experimental approaches on tissue specimens and plasma samples classified based on pathological characteristics. Patients with carotid-unstable plaques exhibited elevated plasma concentrations of MD-1 (LY86), while patients with stable plaques demonstrated comparatively lower levels. Furthermore, soluble MD-1 was found to induce the formation of NETs through activation of Toll-like receptor signaling pathway. The proliferative and immature vascularization effects of NETs on endothelial cells, as well as their inhibitory impact on cell migration, are directly correlated with the concentration of NETs. Additionally, NETs were found to activate the NF-κB signaling pathway, thereby upregulating ICAM1, VCAM1, MMP14, VEGFA, and IL6 expression in both Human umbilical vein endothelial cells (HUVECs) and HAECs. Subsequently, a significant increase in intraplaque neovascularization by NETs results in poor carotid plaque stability, and NETs in turn stimulate macrophages to produce more MD-1, generating a harmful positive feedback loop. Our findings suggest that soluble MD-1 in the bloodstream triggers the production of NETs through activation of the Toll-like receptor signaling pathway and further indicate NETs mediate a crosstalk between the microenvironment of the carotid plaque and the neovascularization of the intraplaque region. Inhibiting NETs formation or MD-1 secretion may represent a promising strategy to effectively suppress the development of unstable carotid plaques.

      • KCI등재

        Phenotypes and Prognostic Factors of Syringomyelia in Single-Center Patients With Chiari I Malformation: Moniliform Type as a Special Configuration

        Chunli Lu,Longbing Ma,Chenghua Yuan,Lei Cheng,Xinyu Wang,Wanru Duan,Kai Wang,Zan Chen,Hao Wu,Gao Zeng,Fengzeng Jian 대한척추신경외과학회 2022 Neurospine Vol.19 No.3

        Objective: The specific association between morphometric characteristics of the syrinx and the prognosis of Chiari malformation type I (CM-I) with syringomyelia following surgical procedure seems to have not been fully elaborated. This study focused on the preoperative clinical and radiologic parameters in CM-I patients with syringomyelia to find out the relationship between the patients’ clinical status and the phenotypes of the syrinx with surgical outcome. Methods: A continuous series of pediatric and adult patients with CM-I and syringomyelia from a prospectively maintained database in a single center were included, and we explored the related factors affecting the prognosis following decompression surgery through retrospective analysis of clinical presentations, imaging characteristics, and the morphological features of syringomyelia, to provide a clinical reference for the treatment of syringomyelia. Results: There were 28 pediatric patients (13.8%), and 174 adults (86.2%) included in our study. The average Chicago Chiari Outcome Scale score was 14.56 ± 1.78. The overall prognosis after surgery was good in our series, among them 152 cases (75.25%) with a favorable prognosis, and syrinx was resolved effectively in 172 cases (85.15%). According to the univariate and multivariate analyses, the preoperative symptom duration, observation time, and with/without moniliform type were independent factors affecting the prognosis in adults. The most obvious difference between moniliform type and nonmoniliform type lies in the preoperative symptom duration, ventral subarachnoid space at the foramen magnum, and with/without straightened cervical physio-curve. Conclusion: Timely decompression surgery could achieve a better outcome in CM-I patients with syringomyelia. Moniliform syringomyelia may suggest a relatively better prognosis.

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