Fault Diagnosis of Wind Power Converters Based on Compressed Sensing Theory and Weight Constrained AdaBoost-SVM

Xiao-Xia Zheng,Peng Peng 전력전자학회 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.2

As the core component of transmission systems, converters are very prone to failure. To improve the accuracy of fault diagnosis for wind power converters, a fault feature extraction method combined with a wavelet transform and compressed sensing theory is proposed. In addition, an improved AdaBoost-SVM is used to diagnose wind power converters. The three-phase output current signal is selected as the research object and is processed by the wavelet transform to reduce the signal noise. The wavelet approximation coefficients are dimensionality reduced to obtain measurement signals based on the theory of compressive sensing. A sparse vector is obtained by the orthogonal matching pursuit algorithm, and then the fault feature vector is extracted. The fault feature vectors are input to the improved AdaBoost-SVM classifier to realize fault diagnosis. Simulation results show that this method can effectively realize the fault diagnosis of the power transistors in converters and improve the precision of fault diagnosis.

Effects of microRNA-135a on the epithelial–mesenchymal transition, migration and invasion of bladder cancer cells by targeting GSK3β through the Wnt/β-catenin signaling pathway

Xia-Wa Mao,Jia-Quan Xiao,Zhong-Yi Li,Yi-Chun Zheng,Nan Zhang 생화학분자생물학회 2018 Experimental and molecular medicine Vol.50 No.-

This study investigated the effects of microRNA-135a (miR-135a) targeting of glycogen synthase kinase 3β (GSK3β) on the epithelial–mesenchymal transition (EMT), migration and invasion of bladder cancer (BC) cells by mediating the Wnt/β-catenin signaling pathway. BC and adjacent normal tissues were collected from 165 BC patients. Western blotting and quantitative realtime PCR were used to detect the expression of GSK3β, β-catenin, cyclinD1, E-cadherin, vimentin and miR-135a in BC tissues and cells. Cells were assigned to blank, negative control (NC), miR-135a mimics, miR-135a inhibitors, small interfering RNA (siRNA)-GSK3β or miR-135a inhibitors+siRNA-GSK3β groups. miR-135a, β-catenin, cyclinD1 and vimentin expression increased, while GSK3β and E-cadherin expression decreased in BC tissues compared with adjacent normal tissues. Compared with the blank and NC groups, the expression of miR-135a, β-catenin, cyclinD1 and vimentin was higher, and cell proliferation, migration, invasion and tumor growth were increased in the miR-135a mimics and siRNA-GSK3β groups. These groups showed an opposite trend in GSK3β and E-cadherin expression and cell apoptosis. The miR-135a inhibitors group was inversely correlated with the blank and NC groups. It was concluded that miR-135a accelerates the EMT, invasion and migration of BC cells by activating the Wnt/β-catenin signaling pathway through the downregulation of GSK3β expression.

Optimal Monochromatic Imaging of Spectral Computed Tomography Potentially Improves the Quality of Hepatic Vascular Imaging

Xiao-Ping Yin,Bu-Lang Gao,Cai-Ying Li,Huan Zhou,Liang Zhao,Ya-Ting Zheng,Yong-Xia Zhao 대한영상의학회 2018 Korean Journal of Radiology Vol.19 No.4

Objective: To investigate the efficiency of spectral computed tomography (CT) optimal monochromatic images in improving imaging quality of liver vessels. Materials and Methods: The imaging data of 35 patients with abdominal CT angiography were retrospectively analyzed. Hepatic arteries, portal veins, and hepatic veins were reconstructed with mixed energy (quality check, QC), 70 keV and optimal monochromatic mode. Comparative parameters were analyzed including CT value, image noise (IN), contrast-to-noise ratio (CNR), signal-to-noise ratio (SNR), and subjective qualitative analysis. Results: The optimal monochromatic value for assessment of the common hepatic artery, portal vein, and hepatic vein ranged between 49 keV and 53 keV, with a mean of 51 keV. There were statistically significant differences (p < 0.001) among the optimal monochromatic, 70 keV and QC images with regards to the hepatic vascular CT value, IN, CNR, SNR, and subjective qualitative score. CNR of the common hepatic artery in the optimal monochromatic, 70 keV and QC groups was 24.6 ± 10.9, 18.1 ± 8.3, and 11.6 ± 4.6, respectively (p < 0.001) with subjective scores of 4.7 ± 0.2, 4.0 ± 0.3, and 3.6 ± 0.4, respectively (p < 0.001). CNR of the hepatic portal vein was 6.9 ± 2.7, 4.3 ± 1.9, and 3.0 ± 2.1, respectively (p < 0.001) with subjective scores of 4.5 ± 0.3, 3.9 ± 0.4, and 3.3 ± 0.3, respectively (p < 0.001). CNR of the hepatic vein was 5.7 ± 2.3, 4.2 ± 1.9, and 2.7 ± 1.4, respectively with subjective scores of 4.3 ± 0.3, 3.8 ± 0.4, and 3.2 ± 0.3, respectively (p < 0.001). Conclusion: Optimal monochromatic images can lead to improvement in the imaging parameters and optimization of the image quality of the common hepatic artery, hepatic portal vein and hepatic vein compared with conventional mixed kV and with 70 keV datasets.

Novel Stationary Phase Expression System in Escherichia coli for the Production of Recombinant Protein

Shun Zheng,Tae Jung Park,Xiao Xia Xia,Hyun Uk Kim,Sang Yup Lee 한국생물공학회 2008 한국생물공학회 학술대회 Vol.2008 No.4

Synthesis of biscoumarin and dihydropyran derivatives as two novel classes of potential anti-bacterial derivatives

Jing Li,Xiao-yan Xue,Xia Li,Zheng Hou,Xiao-hui Yang 대한약학회 2016 Archives of Pharmacal Research Vol.39 No.10

A series of bisoumarin (1–4) and dihydropyran (5–8) derivatives were successfully synthesized as new antibacterial agents. The molecular structures of three representative compounds 1, 5 and 7 were confirmed by single crystal X-ray diffraction study. Among these compounds tested toward Staphylococcus aureus (S. aureus ATCC 29213), methicillin-resistant S. aureus (MRSA XJ 75302), vancomycin-intermediate S. aureus (Mu50 ATCC 700699), and USA 300 (Los Angeles County clone, LAC), compounds 1 and 2 displayed the most potent antibacterial activity. Additionally, the HB energy in biscoumarins 1–4 was calculated by density functional theory (DFT) [B3LYP/6-31G*] method.

β-arrestin Promotes c-Jun N-terminal Kinase Mediated Apoptosis via a GABA_BR·β-arrestin·JNK Signaling Module

Wu, Jin-Xia,Shan, Feng-Xiao,Zheng, Jun-Nian,Pei, Dong-Sheng Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.2

Evidence is growing that the $GABA_B$ receptor, which belongs to the G protein-coupled receptor (GPCR) superfamily, is involved in tumorigenesis. Recent studies have shown that ${\beta}$-arrestin can serve as a scaffold to recruit signaling protein c-Jun N-terminal knase (JNK) to GPCR. Here we investigated whether ${\beta}$-arrestin recruits JNK to the $GABA_B$ receptor and facilitates its activation to affect the growth of cancer cells. Our results showed that ${\beta}$-arrestin expression is decreased in breast cancer cells in comparison with controls. ${\beta}$-arrestin could enhance interactions of the $GABA_BR{\cdot}{\beta}-arrestin{\cdot}JNK$ signaling module in MCF-7 and T-47D cells. Further studies revealed that increased expression of ${\beta}$-arrestin enhances the phosphorylation of JNK and induces cancer cells apoptosis. Collectively, these results indicate that ${\beta}$-arrestin promotes JNK mediated apoptosis via a $GABA_BR{\cdot}{\beta}-arrestin{\cdot}JNK$ signaling module.

Revelation of the early responses of salt tolerance in maize via SSH libraries

Dong Ding,Zhixia Xiao,Hailin Xiao,Tao Xia,YongLian Zheng,Fazhan Qiu 한국유전학회 2012 Genes & Genomics Vol.34 No.3

Maize (Zea mays L.), one of the most important cereal crops in the world, is salt-sensitive. It is critical to study the genes associated with salt tolerance, the differential gene expression pattern between salt-tolerant and salt-sensitive lines, and the mechanism of salt tolerance in maize. Two maize inbred lines with different salt sensitivity, NC286 and Huangzao4, were used to reveal early responsive genes under high salinity condition. Suppression subtractive hybridization (SSH) assay was conducted to identify potential genes involved in the early stage of maize seedlings in responses to 200mM NaCl. A custom μparafloTM microfluidic array (LC science USA) containing Release version 10.1 plant miRNA probes (http://microrna. sanger.ac.uk/) was used to discover salt stress responsive miRNAs using the differences in miRNAs expression between these two maize lines. Cis-elemnet analysis was performed in the promoter regions of these two kinds of salt stress responsive transcriptions. The expression of a total of 141unique genes was significantly changed under 200mM NaCl salt shock within 24 hours. These genes were involved in a broad spectrum of biochemical, cellular, and physiological processes. They were assigned to 14 categories based on their biological functions. Some of them were previously reported to be associated with biotic and abiotic stresses, and several novel genes detected. A gene model was proposed which showed how these genes could sense and response to the high salinity environment. The promoter regions of these 141 salt responsive genes were analyzed, and salt responsive key cis-elements uncovered. The cis-elements usage bias of the salt responsive mRNAs and non-coding RNAs were of the same. The different expression profiles of the genes, especially the ones involved in salt signal cascades and phytohormones responding,could explain the different salt stress response in the two maize inbred lines. The similar cis-elements usage bias of two kinds of salt responsive transcriptions suggests they may be regulated by the same trans-factors.

Comparative transcriptomic screen identifies expression of key genes involved in pattern-triggered immunity induced by salicylic acid in strawberry

Feng Jun,Wu Xiao-Ying,Xiu Yu,Zheng Cai-Xia 한국원예학회 2023 Horticulture, Environment, and Biotechnology Vol.64 No.5

The destructive illness powdery mildew, caused by Podosphaera aphanis , reduces strawberry yield. However, the mechanism through which exogenous salicylic acid can enhance resistance to P. aphanis remains unknown. Therefore, this study aimed to investigate the underlying mechanism of SA-induced resistance in strawberry leaves against P. aphanis using a comparative RNA-seq approach. Upon observing the symptoms, it was found that SA partially contributed to strawberry resistance against P. aphanis by increasing H 2 O 2 levels during the initial stages. To mitigate the eff ects of H 2 O 2 , SA-treated leaves signifi cantly boosted the activities of enzymes such as superoxide dismutases (SOD), catalases (CAT), and peroxidases (POD). RNA profi ling identifi ed several diff erentially expressed genes (DEGs) associated with the reactive oxygen species (ROS)-redox pathway. Moreover, SA-induced leaves fortifi ed the cell wall to prevent P. aphanis penetration. Using weighted gene coexpression network analysis (WGCNA), three modules (red, green, and yellow) were constructed, showing a strong correlation with enhanced resistance. Predictably, cyclic nucleotide-gated channels (CNGC) were identifi ed as potential players in Ca 2+ signaling linked to the PTI response. Additionally, the presence of WRKY33 and defense-related genes such as PR10 were associated with enhanced resistance. It is plausible that strawberries exposed to SA trigger ROS and Ca 2+ signaling, along with signifi cantly elevated WRKY33 expression, to facilitate the production of PR10 and camalexin, which help protect against P. aphanis .

Use of Beauveria bassiana in combination with commercial insecticides to manage Phauda flammans (Walker) (Lepidoptera: Phaudidae): Testing for compatibility and synergy

Chen Xue-Min,Wang Xiao-Yun,Lu Wen,Zheng Xia-Lin 한국응용곤충학회 2021 Journal of Asia-Pacific Entomology Vol.24 No.2

An entomopathogenic fungal strain, Beauveria bassiana PfBb, was identified from Phauda flammans (Lepidoptera: Phaudidae) larvae. The compatibility and synergy of B. bassiana PfBb employed in combination with three concentrations (i.e., recommended concentration, 20% and 10% of the recommended concentration) of five commercial insecticides were determined. Beta cypermethrin at 10% of recommended concentration had the lowest inhibitory effect on the mycelial growth of B. bassiana PfBb compared with other insecticides. Insecticides utilized at recommended concentration had no significant effect on the sporulation of B. bassiana PfBb, while the extent of their effect at 20% and 10% of recommended concentration differed among insecticides. Insecticides at 10% of recommended concentration had the lowest inhibition of sporulation and conidial germination compared with other concentrations. The conidial germination of B. bassiana PfBb was the highest after treatment with beta cypermethrin at 10% of recommended concentration. The cumulative mortality for 1 × 10 7 spores/mL B. bassiana PfBb combined with each insecticide at 10% of recommended concentration was higher than that observed with the application of insecticides alone. The percent cadavers of Phauda flammans larvae observed after treatment with B. bassiana PfBb combined with beta cypermethrin at 10% of recommended concentration were not significantly different from those observed after infection with B. bassiana PfBb alone. Our findings demonstrate that B. bassiana PfBb combined with beta cypermethrin at 10% of recommended concentration could increase the efficiency of this insecticide.

Current understanding of the development of sex attractant-based biocontrol in burnet moths

Chen Xue-Min,Wang Xiao-Yun,Lu Wen,Zheng Xia-Lin 한국응용곤충학회 2021 Journal of Asia-Pacific Entomology Vol.24 No.3

Burnet moths, also known as the family Zygaenidae, are a typical diurnal family of Lepidoptera. Some species are important insect pests in agriculture and forestry. The use of sex attractants is one of the most important mea sures in the integrated pest management of burnet moths because these attractants are highly efficient, do not cause pollution, and are convenient and harmless to natural enemies. The earliest information about sex pher omones in Zygaenidae was reported in 1972. To date, many studies have described sex pheromones and at tractants of species in Zygaenidae. Here, we review a total of 22 sex attractant compositions identified for 57 species of Zygaenidae and compare the differences in the structures of sex attractants among these species. The application of sex attractants in seasonal monitoring showed that the main activity period of zygaenid moths is from May to September each year. However, there are few reports on the effects of sex attractants on mass trapping of members of the family Zygaenidae. The ratio and degradation of sex attractants and the trap color, shape and hanging height were considered the main factors influencing capture effectiveness. Directions for further study of burnet moths are also discussed.