온도변화에 따른 복층 OLED의 물리적 특성 연구

채우리;이유근;최성진;채희백 순천향대학교 기초과학연구소 2010 순천향자연과학연구 논문집 Vol.16 No.2

OLEDs of the bilayer structure with ITO/NPB/Alq3/LiF/Al were fabricated by vacuum thermal evaporation. I-V-L(current-voltage-luminance) and charge mobility could be measured with TEL(transient electroluminescence) as the temperature was varied from 300K to 50 K. Current, current density and EL were decreased as the temperature was decreased.

DCJTB를 도핑시킨 단층 Alq₃소자에서 Two-color filter를 사용한 발광영역의 결정

채우리,채희백,최성진 순천향대학교 기초과학연구소 2011 순천향자연과학연구 논문집 Vol.17 No.2

A doping layer of thickness 2 nm of DCJTB(guest) was dopoed 1 % and varied its location 5nm each from the anode to the cathode in a single layer Alq(60 nm, host) OLED in order to investigate the region of charge recombination and light emission. Major emission peak was located 20 nm from the anode and the emission region was shown to be spread through the whole layer of Alq. We also investigate a method to determine the recombination zone with two-color filter from TEL

양극성 장애, 조증 삽화 입원 환자에서 조증 증상 경과 예측과 관련있는 임상 변인 연구

김채리(Chae-Ri Kim),박진완(Jin-Wan Park),백두현(Doo-Hyun Pak),이연정(Yeon-Jung Lee),한상우(Sang Woo Hahn),우성일(Sungil Woo),황재욱(Jaeuk Hwang) 대한생물치료정신의학회 2017 생물치료정신의학 Vol.23 No.3

Objectives:This study was aimed to investigate clinical factors associated with the prediction of symptom improvement in hospitalized patients with bipolar disorder, manic episode. Methods:We performed a retrospective observational study based on the medical records review of 53 bipolar disorder manic patients, who had been hospitalized in the psychiatric ward. During the hospitalization, Young Mania Rating Scales(YMRS) have been measured periodically. Demographic information and clinical characteristics including medications and history of prior hospitalization have been collected in each patient. Linear mixed effect model has been used to assess the effect of clinical factors on the changes of YMRS over time. Selection of clinical factors was conducted using backward elimination with the minimization of Akaike Information Criterion. Results:Mean days of hospitalization were 29.74±16.96. Mean YMRS at the admission was 33.64±7.57. Effective factors for the model included YMRS at baseline, combination of mood stabilizer, and the history of prior hospitalization. Predicted YMRS at the discharge was 10.43(95% confidence interval 7.13–13.72). Conclusion:The current findings suggest the model which may predict the clinical course of the bipolar disorder manic patients. It would be useful to establish the treatment plan for the patients.

Financial Market Integration of the EU pre- and post- global financial crisis

Chae Deug Yi,Woo Ri Lim 한국유럽학회 2013 유럽연구 Vol.31 No.1

EU는 단일시장 출범이래 하나의 경제권으로서의 통합을 추구하기 위하여 노력해왔고 2008년 EU의 재정금융위기가 오기 전까지는 어느 정도 성과가 있었다. 그러나 2008년의 EU의 재정금융위기는 EU통합에 중요한 난관으로 작용하고 있고 EU국가뿐만 아니라 전 세계적으로도 경제위기를 몰고 왔다. 따라서 본 논문은 그 동안 많은 연구가 있어왔던 실물경제 및 무역 측면의 통합이 아니라, 그 동안 연구가 상대적으로 희소했던 EU 금융시장의 통합과 상호작용 그리고 EU 금융시장이 어떻게 긴밀히 연계되어 있는지를 분석한다. 특히 2008년 재정금융 전후 금융통합과 연계정도를 분석 위하여 2001년부터 2011년까지의 EU 주요11개국 증권시장 자료를 이용하여 VAR분석과 공적분 분석 등을 중심으로 살펴보았다. 실증분석결과 EU의 증권시장은 상호 깊이 연계 혹은 통합되어 있었으며 금융위기 전 후 비슷하게 상호연계 되어 있었으나 전체적으로 금융위기 전보다 금융위기 후에 금융증권시장의 연계정도가 다소 낮게 나타났고 국가별로도 금융충격에 약간 상이하게 나타났지만 대체적으로 심각한 위기를 겪었던 국가들이 좀 더 외부의 금융충격에 더 많은 영향을 받는 것으로 나타났다. Since the establishment of the EU and European single market, there have been successful initiatives and attempts to make the deepened economic integration and the monetary or financial union.The financial crisis of 2008 has, however, severely negative affected financial markets and economic activity in all advanced and global financial markets The global financial markets have been threatened by EU member`sdebt problems and EU member countries have started to rebalance positive macroeconomic signs from the global financial crisis in year 2008. This paper investigates the degree of financial interdependence and transmission process of stock markets among the EU regions using 11 EU stock markets from 2001 to 2011. Thus, this paper analyses the degree of financial or stock markets interdependences or linkages comparing pre- and post- period of financial crisis in 2008 in the EU regions by dealing with the stock data through 2001~2011 mainly using the VAR and cointegration approach. The empirical results give several implications on the stock market interdependences among 11 EU countries. The degrees of the stock market integration or the financial integration are compared pre- and post- global financial crisis. General trend of the degree of financial or stock markets interdependences or linkages in the EU is similar in both post period of the financial crisis and that of pre-period. Yet the financial impact ofstock markets becomes little lower than before that of the crisis.

ASEAN+3`s Lessons from EU Integration

Chae Deug Yi,Soo Min Jeon,Woo Ri Lim 한국유럽학회 2012 유럽연구 Vol.30 No.2

본 논문은 EU 통합으로부터 ASEAN+3 국(중국, 일본, 한국)의 통합과정에 대한 해석과 지역간 통합의 비교로부터 교훈과 정책적 함의를 논의한다. EU 재정위기가 도래하기 이전에 EU 의 경제통합이 ASEAN+3 국(중국, 일본, 한국)에 대해 무역량증가와 경제성장에 대해 많은 교훈을 주지만, ASEAN+3 국(중국, 일본, 한국)은 EU 와 역사적, 정치적, 경제적, 문화적 환경과 배경이 상당히 다르다. 또한 ASEAN+3 국(중국, 일본, 한국)은 통합과정에 있어, 발전과정과 통합에 대한 요소들이 다르다. 그래서 EU 통합의 경험이 ASEAN+3 국(중국, 일본, 한국)에 많은 시사점과 교훈을 주지만, ASEAN+3 국(중국, 일본, 한국) 는 EU 통합의 경험으로부터 긍정적인 측면과 부정적인 측면을 창의적으로 고려하여 EU 통합과는 다른 ASEAN+3 국(중국, 일본, 한국)의 시각으로부터 아시아의 특이한 사회, 경제, 문화, 정치적 요소를 고려하여 서로 윈-윈이 되는 통합전략과 제 3 의 통합모형을 모색해야 한다. Regionalism has appeared inevitable in the globalized world in the Post-Cold War international order. The European Union can be seen as an important model of successful regional integration with the deepening and widening of integration. In addition, East Asian countries have become more influential in regional and global regionalism. East Asia has, however, no region-wide institutional arrangement and economic integration. In that sense, the regional integration process in Asia has become one of the most frequently discussed issues in recent years. The most visible progress of Asian cooperation can be found in the development of ASEAN+3 processes. Even though there have been many initiatives and attempts to make the integration in Asia, there are a number of internal factors as well as external ones which have constrained it. This paper will argue that EU integration appears to offer ASEAN+3 political and economic lessons concerning maintenance of regional stability and economic lessons. Due to contextual differences, however, between the EU and ASEAN+3, it is believed that EU integration cannot be an exact role model for ASEAN+3 to follow. One of the debates is what we can learn from the European experience and integration. In addition, many questions about the extent of European experience to apply to the Asian integration remain unanswered. In this paper, we compare the ASEAN+3 integration process with that of the EU. Before mentioning the ASEAN+3`s lessons learned from the EU, we will begin with the analysis of the EU and ASEAN+3 in terms of the current situations and their features respectively. Then, we will compare ASEAN+3 with the EU concerning the integration process in terms of historical experience, development process, and factors which have influenced integration. We can make implications for the future of ASEAN+3`s integration politically and economically. In this part, we can see the positive lessons from the EU integration as well as the negative ones. To have a desirable institutional form of ASEAN+3 integration, ASEAN+3 countries need to be actively involved in creating a win-win integration considering the various social and economic factors and they need to share a common regional identity of East Asia. With the consideration of the lessons as a whole, we will suggest some prospects that ASEAN+3 should promote to achieve in the future.

Technology Innovation, Human Capital and R&D Effects on Economic Growth

( Woo Ri Lim ),( Chae Deug Yi ) 국제지역학회 2017 국제지역연구 Vol.21 No.1

This paper analyzes the economic effects of the S&T Innovation, R&D, human resources and investment on the economic growth using 18 countries. We have obtained the somewhat mixed results on the existence of unit root roots in variables. While most of Pedroni cointegration tests show that there are no panel cointegration among the variables, Kao cointegration test shows that there is the panel cointegration among the variables such as GDP, human capital, R&D investment and patent. Kao cointegration test result shows that human capital, R&D investment, patent economic growth seem to have the panel cointegration or the long-run relationship among them as a whole. The estimation results of individual OLS and panel estimation show that the human capital, R&D investment and technology innovation or patent had positively significant effects on economic growth or GDP.

Chronic alcohol consumption induces migration of IL-1R2+ monocytes from the bone marrow into the liver by neuro-immunologic pathway

Young-Ri Shim,Hee-Hoon Kim,Keungmo Yang,Tom Ryu,Kyurae Kim,Sung Eun Choi,Minjeong Kim,Chae-Rin Woo,Young-Sun Lee,Won-Il Jeong 한국실험동물학회 2021 한국실험동물학회 학술발표대회 논문집 Vol.2021 No.7

Liver is challenged by diverse detrimental substances through multiple metabolic processes, but it is less prone to inflammation. In chronic alcohol consumption, although the migration of monocytes from bone marrow (BM) into liver is increased, alcoholic hepatitis rarely occurs. Thus, we investigated the sub-population of liver macrophages showing anti-inflammatory roles through single-cell RNA sequencing (scRNA-Seq) after chronic EtOH-feeding. Interestingly, in scRNA-seq and flow cytometry analyses of hepatic macrophages, the phenotype of Ly6Clow (anti-inflammatory) cells was dramatically altered by ethanol intake. In particular, they were highly expressed interleukin-1 type II receptor (IL-1R2), a decoy receptor of IL-1β. Intriguingly, IL-1R2+ Ly6Clow macrophages showed decreased CX3CR1 expression, which was confirmed not only in the liver, but also BM and blood, suggesting monocytes from BM affected by ethanol might migrate into the liver. We found that the Leptin Receptor+ mesenchymal stromal cells (LepR+ MSCs), which were located around blood vessels expressing CX3CL1 to hold CX3CR1+ macrophages, could express alcohol dehydrogenase to metabolize ethanol in BM. Ethanol metabolism in LepR+ MSCs was induced both production of chemokines (CXCL9 and 10) and the excretion of glutamate via cystine-glutamate anti-porter xCT to recruit and activate the CXCR3+ BM NK cells to produce interferon-γ in a metabotropic glutamate receptor 5 (mGluR5)-dependent manner. Indeed, IFN-γ production was significantly decreased in EtOH-fed mice when we depleted mGluR5 in NK cells. In turn, NK cell-derived IFN-γ down-regulated CX3CR1 expression in BM Ly6Clow monocytes, consequently induced egress of Ly6Clow monocytes into the blood and migration into the liver to suppress alcoholic inflammation. In conclusion, glutamate of LepR+ MSCs imposed egress license on anti-inflammatory IL-1R2+ Ly6Clow monocytes through NK cell-derived IFN-γ-mediated suppression of CX3CR1, suggesting a potential therapeutic inter-organ crosstalk between BM and liver in alcoholic liver disease.

Assessment of Growing Media and Fertigation for Production of Root Pruning Splice-Grafted Cucumber Seedlings

Hyeon Woo Jeong,Hye Ri Lee,Ju Yeon Kim,Gam Gon Kim,Chae In Na,Seung Jae Hwang 한국원예학회 2021 원예과학기술지 Vol.39 No.3

In the Republic of Korea, the root pruning splice-grafting method is commonly used on watermelon (Citrullus lanatus) and cucumber (Cucumis sativus) seedlings to produce grafted plants. The growing medium is an important factor for rooting a transplant. In this study, we investigated the shoot growth and root development of cucumber seedlings in different growing media. ‘Shindong’ cucumber seedlings as scions were grafted onto ‘Shingiwon’ bottle gourd (Lagenaria siceraria) seedlings as rootstocks using the root-pruning one-cotyledon splice-grafting method. The grafted seedlings were transplanted into five different media: commercial growing medium (CGM), rockwool (RW), LC grow foam (LC), RC grow foam (RC), and terra-plug (TP). We also investigated the effect of fertigation on plant growth in the different media. Root morphology was significantly influenced by all five media. The total root length, root volume, and root surface area were greatest in the CGM. However, inorganic media (RW, LC, and RC) resulted in low root growth. Fertigation increased root growth, especially in the CGM. Root growth affected the shoot growth of cucumber seedlings. The shoot growth of cucumber seedlings was greatest in the CGM and TP medium, which also had good root development. In conclusion, CGM with fertigation was advantageous for cucumber root development and growth, and TP showed promise for use as a growing medium in the seedling stage.

인천지역 유기동물 현황 및 개 질병 조사

윤가리 ( Ga Ri Yun ),정은하 ( Eun Ha Jung ),라도경 ( Do Kyung Ra ),정철 ( Cheol Jeong ),이경민 ( Kyung Min Lee ),채현우 ( Hyun Woo Chae ),이정구 ( Jung Goo Lee ),이성모 ( Sung Mo Lee ) 한국동물위생학회 2014 한국동물위생학회지 (KOJVS) Vol.37 No.4

Animals and disease frequency of the rescued dogs were investigated in Incheon Veterinary Medical Association Animal Shelter from January in 2012 to December in 2013. Three zoonoses (rabies, brucellosis, and dirofilariosis) and three infectious diseases (canine distemper, canine parvoviral enteritis, and canine influenza) were examined for stray dogs. Among 5,603 heads, 647 (11.5%) went back to their owner and 969 (17.3%) were adopted to new families. Prevalence of dirofilariosis, canine distemper and canine parvoviral enteritis were 2.2% (16/718), 6.0% (24/399) and 6.1% (24/396), respectively. Positive antibody rates against rabies, B. canis and canine influenza virus were 20.5% (41/200), 0.1% (1/718) and 2.0% (4/200), respectively. Protective antibody for canine distemper virus and canine parvovirus were shown in 47.0% (94/200). The data indicate that control measures including facility standards and disease control program are one of the important aspects of the shelter management because stray dogs are exposed to various infectious agents.

Three dimensional poly(ε-caprolactone) and silk fibroin nanocomposite fibrous matrix for artificial dermis

Lee, Jung Min,Chae, Taesik,Sheikh, Faheem A.,Ju, Hyung Woo,Moon, Bo Mi,Park, Hyun Jung,Park, Ye Ri,Park, Chan Hum Elsevier 2016 Materials science & engineering. C, Materials for Vol.68 No.-

<P>Ideal dermal substitutes should have comparable physicochemical and biological properties to the natural skin tissue. In this study, we report a novel strategy to 'engineer' controlled 3D nanocomposite fibrous matrix of poly(epsilon-caprolactone) (PCL) and silk fibroin (SF) for an artificial dermis application. Using a custom-designed cold-plate electrospinning and automatic magnet agitation system, up to 6 mm of the thickness was achieved resulting from the accumulation of ice crystal layers on the PCL nanofibers surface-modified with the SF particles. The sacrificed ice crystals induced interconnected macro-pores ranging from tens to hundreds pm. The agitation system introduced uniform distribution of the SF protein within/on the nanofibers, preventing the particles from precipitation and agglomeration. NIH 3T3 fibroblasts proliferated in vitro on the PCL and PCL/SF scaffolds for 7 days, but there was no statistical difference between the groups. Conversely, In vivo rat model studies revealed that the wound healing rate and collagen deposition increased with the SF content within the nanocomposites. The unique 3D construct with the PCL/SF nanocomposite fibers provided desirable spatial cues, surface topography, and surface chemistry for the native cells to infiltrate into the scaffolds. The wound healing potential of the nanocomposites was comparable to the commercial Matriderm (R) artificial dermis. (C) 2016 Elsevier B.V. All rights reserved.</P>