전자상거래 웹사이트의 인지 신뢰성에 영향을 미치는 디자인 요인들

황원일(Hwang Wonil) 한국전자거래학회 2008 한국전자거래학회지 Vol.13 No.3

인터넷 웹 기반의 B2C 전자상거래 업체에게 고객의 신뢰(trust)는 상품 가격과 함께 주요 경쟁력의 원천으로 여겨진다. 이 때 신뢰는 신뢰 대상자에게 신뢰성(trustworthiness)이 있고 신뢰하는 자에게 인식되어야 형성되는 태도로 이해된다. 전자상거래 웹사이트는 이러한 인지 신뢰성(perceived trustworthiness)이 형성되고 고객에게 전달되는 주요 통로이기 때문에 웹사이트 디자인의 중요성이 더욱 강조된다. 본 연구는 50명에 대한 인터뷰와 831명에 대한 설문 조사를 바탕으로 전자상거래 웹사이트의 인지 신뢰성에 영향을 미치는 웹사이트 디자인 요인을 도출하고 그 영향력을 비교하였다. 그 결과 총 9개의 인지 신뢰성 관련 웹사이트 디자인 요인이 도출되었고, 그 중 6개의 웹사이트 디자인 요인만이 인지 신뢰성에 유효한 영향을 미치는 것으로 확인되었으며, 성별 및 연령에 따라서도 인지 신뢰성에 유효한 영향 을 미치는 디자인 요인들이 달라짐을 발견하였다. Customer’s trust is one of major competitiveness sources along with price in Internet Web-based B2C e-commerce business. In general, trust is defined as the attitude that is established by a trustor when trustworthiness exists in a trustee and is perceived by a trustor. Designing e-commerce websites is important in that e-commerce website is understood as a means of constructing perceived trustworthiness and delivering it to customers. In this study 50 participants were interviewed and total of 831 participants responded to the survey questionnaire to investigate design factors influencing the perceived trustworthiness in e-commerce websites. Nine design factors were derived as the perceived trustworthiness-related design factors, and only six out of nine design factors were found as having significant effects on the perceived trustworthiness of e-commerce websites. In addition, the significant design factors were different according to gender and ages of e-commerce customers.

Universal monoclonal antibody-based influenza hemagglutinin quantitative enzyme-linked immunosorbent assay

Chae, Wonil,Kim, Paul,Hwang, Beom Jeung,Seong, Baik Lin Elsevier 2019 Vaccine Vol.37 No.11

<P><B>Abstract</B></P> <P>Seasonal and pandemic influenza infections remain a serious public health concern. Many health authorities recommend annual vaccination as the most effective way to control influenza infection. Accordingly, regulatory guidelines ask vaccine manufacturers to determine vaccine potency at the time of release and throughout shelf-life to ensure vaccine quality. The potency of inactivated influenza vaccine is related to the quantity of hemagglutinin (HA). Since 1970s, single radial immunodiffusion (SRID) assay has been standardly used for the quantitation of HA in influenza vaccine. However, SRID is labor-intensive, inaccurate, and requires standard reference reagents that should be updated annually. Therefore, there have been extensive efforts to develop alternative potency assays. In this study, we developed and tested a new HA quantitative enzyme-linked immunosorbent assay (ELISA) using a universal monoclonal antibody that can bind to HAs from various subtypes in group 1 influenza A virus (IAV). We analyzed the conserved stalk domain of HA via a library approach to design a consensus HA antigen for group 1 IAV. The antigens were expressed as a soluble form in <I>E. coli</I> and were purified by Ni-affinity chromatography. When tested with variety of HAs from IAVs or influenza B viruses (IBVs), the mAbs exhibited specific binding to group 1 HAs, with potential exception to H9 subtype. Among various conditions of pH, urea, and reducing agents, pretreatment of HA at low pH exposing the conserved stalk domain was crucially important for optimal ELISA performance. Calibration curves for various HAs were generated to determine accuracy, specificity, sensitivity, and linear dynamic range. The ELISA method shows high sensitivity and accuracy compared with the SRID assay. The HA group specific universal mAbs against the consensus stalk domain of HA are conducive to establishing an ELISA-based standard procedure for the quantitation of HA antigens for annual vaccination against influenza infection.</P> <P><B>Highlights</B></P> <P> <UL> <LI> We developed a novel HA quantitative ELISA as an alternative for SRID. </LI> <LI> The ELISA uses broadly reactive group-specific universal mAbs. </LI> <LI> The assay is less time-consuming than the SRID assay. </LI> <LI> The assay has good accuracy, specificity, sensitivity and reproducibility. </LI> <LI> The assay performs better than SRID in terms of accuracy and sensitivity. </LI> </UL> </P>

Bayesian analysis of longitudinal traits in the Korea Association Resource (KARE) cohort

Chung, Wonil,Hwang, Hyunji,Park, Taesung Korea Genome Organization 2022 Genomics & informatics Vol.20 No.2

Various methodologies for the genetic analysis of longitudinal data have been proposed and applied to data from large-scale genome-wide association studies (GWAS) to identify single nucleotide polymorphisms (SNPs) associated with traits of interest and to detect SNP-time interactions. We recently proposed a grid-based Bayesian mixed model for longitudinal genetic data and showed that our Bayesian method increased the statistical power compared to the corresponding univariate method and well detected SNP-time interactions. In this paper, we further analyze longitudinal obesity-related traits such as body mass index, hip circumference, waist circumference, and waist-hip ratio from Korea Association Resource data to evaluate the proposed Bayesian method. We first conducted GWAS analyses of cross-sectional traits and combined the results of GWAS analyses through a meta-analysis based on a trajectory model and a random-effects model. We then applied our Bayesian method to a subset of SNPs selected by meta-analysis to further discover SNPs associated with traits of interest and SNP-time interactions. The proposed Bayesian method identified several novel SNPs associated with longitudinal obesity-related traits, and almost 25% of the identified SNPs had significant p-values for SNP-time interactions.

27라운드 SKIPJACK에 대한 포화 공격

황경덕(Kyungdeok Hwang),이원일(Wonil Lee),이성재(Sungjae Lee),이상진(Sangjin Lee),임종인(Jongin Lim) 한국정보보호학회 2001 정보보호학회논문지 Vol.11 No.5

Emotional Analysis of Human Motion for the Silver Robots

Euijung Yang,Wonil Hwang,Taezoon Park,Jihong Hwang 대한인간공학회 2011 대한인간공학회 학술대회논문집 Vol.2011 No.5

Objective: The aim of this study is to investigate the preferred human motions and their physical characteristics to design silver robots for the elderly. Background: In the aging society, special cares for the elderly is needed these days. One of the alternatives for caring the elderly is the silver robot. Silver robots' appearance, speech, and haptic elements are actively studied for improving the interaction with the elderly. However there are few studies regarding the robot's motions. Proper motions of silver robots could be designed through investigating the human motions preferred by elderly. Method: Two-phased empirical study was conducted in order to investigate human motions preferred by the elderly. In the first phase, four representative human motions, such as 'greeting', 'I don't know', 'positive answer', and 'giving', were captured through 28 body makers and video recording. 10 young (5 males, 5 females) and 6 elderly (3 males, 3 females) people participated in the motion capture process. In the second phase, the communication efficiency, emotion, and satisfaction of the human motions recorded in the first phase were measured by the questionnaire and 30 elderly people participated. Results: In terms of communication efficiency and satisfaction, female motions were preferred and the elderly motion for 'positive answer' behavior was preferred, whereas the young motions were preferred for the other 3 behaviors. As for the emotion, female motions and young motions were preferred in terms of 'friendliness'. Conclusion: Silver robots need to be designed reflecting the characteristics of human motions preferred by the elderly. Specifically female motions characterized by torso and shoulder motions, and young motions characterized by rapid and big motions need to be considered for the silver robots' design.

실버로봇에 적용하기 위한 인간 동작의 분석

양의정(Yang Euijung),황원일(Hwang Wonil),박태준(Park Taezoon),황지홍(Hwang Jihong) 한국디자인학회 2012 디자인학연구 Vol.25 No.3

Design Factors for Service Interfaces and Usability based on Service Flow and Human Service

Ha-Na Lee,Wonil Hwang,Taezoon Park 대한인간공학회 2013 대한인간공학회 학술대회논문집 Vol.2013 No.10

Objective: The aim of this study is to investigate design factors for service interface and usability based on service flow and human service. Background: Competitive of service organization is determined by service delivery system as management of service processes and motivation of employees. In the other sides, service delivery system as management include interface factor about service flow and human service. However there are few studies regarding the design factors of service interface design. Proper service interface could be designed through investigating the design factor for service interfaces and usability. Method: Entire services industry were divide four type of service industry. Four represent services were selected in the four service industry sector. Service process was divided into three steps. The association between service design factor and usability based on service flow and human service were measured by the questionnaire. Survey was conducted 200 participants of four industries by three steps of service process. Results: In terms of service flow factor, customer-oriented services were preferred for improving satisfaction. In terms of human service factor, the human service that is near by the customer and customer-oriented was preferred. Conclusion: Service delivery system need to be design reflecting the interface between customer and service process by design factors based on service flow and human service. Specifically, design factors are a difference by characteristics of industry sector and service process steps. This study investigated the design factors for service interface design by service sector and service process steps. Based on these results, the guidelines for the design of service interface design have been provided.

만성 신부전 환자의 중풍치료에 대한 한·양방 협진효과 증례보고

황윤경,이보람,김원일,Hwang, Yunkyeong,Lee, Boram,Kim, Wonill 대한한의학방제학회 2016 大韓韓醫學方劑學會誌 Vol.24 No.3

Objective : Chronic renal failure(CRF) is defined as a permanent reduction in glomerular filtration rate(GFR), resulting in Structural and functional abnormalities. The purpose of this thesis is to report the improvement of a CRF stage4 on stroke patient through integrative medicine therapy.Methods : We treated the patient with herbal medication(Sibjeondaebo-tang gagambang), acupuncture and moxibustion as well as Western medication. We measured the Creatinine, BUN, eGFR in the serum and observed clinical symptoms During 4monthsResult : After treatment, the level of BUN and Creatinine was decreased and eGFR was increased. And the symptoms of CRF(edema, anorexia, general weakness) were improved.Conclusion : This study suggests that Integrative Medicine Therapy is effective in the treatment of CRF symptoms. In the future, for the effective management of CRF, It is considered necessary to build a systematic integrative medicine therapy.

Human Parathyroid Hormone Increases the mRNA Expression of the IGF System and Hematopoietic Growth Factors in Osteoblasts, but Does Not Influence Expression in Mesenchymal Stem Cells

Lee, Jong-Hwa,Hwang, Kyou-Jung,Kim, Mi-Yeon,Lim, Yeon-Jung,Seol, In-Joon,Jin, Hye-Jin,Jang, Yun-Kyung,Choi, Soo-Jin,Oh, Wonil,Cho, Youl-Hee,Lee, Young-Ho Lippincott Williams Wilkins, Inc. 2012 Journal of pediatric hematology/oncology Vol.34 No.7

Osteoblasts, which are derived from pluripotent mesenchymal stem cells (MSCs), play an important role in hematopoiesis. Human parathyroid hormone (hPTH) induces osteoblasts to produce many factors that are essential to hematopoietic stem cells. However, little is known about the impact of hPTH on MSCs to enhance hematopoiesis. We determined the optimal dose of hPTH that was necessary in vitro for increased osteoblast function. In addition, we compared MSC and osteoblast function to explore the role of hPTH in hematopoiesis. The mRNA expression levels of granulocyte colony-stimulating factor (G-CSF), granulocyte macrophage colony-stimulating factor (GM-CSF), interleukin 6, stromal cell-derived factor 1, insulin-like growth factor 1 (IGF-1), IGF-2, insulin-like growth factor–binding protein 1 (IGFBP-1), IGFBP-2, and IGFBP-3 were comparable in osteoblasts and human cord blood-derived MSCs. However, G-CSF, GM-CSF, IGF-2, IGFBP-1, IGFBP-2, and IGFBP-3 expression levels in osteoblasts were markedly increased after treatment with 50 or 100 nM of hPTH. In conclusion, hPTH does not affect the ability of MSCs to differentiate into osteoblasts. In addition, hPTH may enhance hematopoiesis by activating the IGF system (IGF-2, IGFBP-1, IGFBP-2, and IGFBP-3) and hematopoietic growth factors (G-CSF and GM-CSF) in osteoblasts, but not in MSCs.

단일전자 트랜지스터의 근사적 전류-전압 특성 계산

유윤섭(Yunseop Yu),하원일(Wonill Ha),황성우(S. W. Hwang) 대한전자공학회 1995 대한전자공학회 학술대회 Vol.1995 No.12