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( Jung Wan Yoo ),( Sang Ho Choi ),( Jin Won Huh ),( Chae Man Lim ),( Youn Suck Koh ),( Sang Bum Hong ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Peramivir, intravenous neuraminidase inhibitor, is available to treat in- uenza in hospitalized patients in South Korea. Whether it provides clinical benefi ts to the critically ill patients with severe in uenza infection admitted to intensitve care unit (ICU)compared to oral oseltamivir remains unclear. Methods: From August 2009 through March 2014, Patients = 18 confi rmed with laboratory evidence of in uenza infection and hospitalized to medical ICU more than 24 hours were enrolled at Asan Medical Center. Study was performed retrospectively Results: Ninety six patients were enrolled; 38 and 58 received peramivir and oseltamivir initially, respectively. SOFA score was higher in patients initiated with peramivir. More clinical complications including shock (68.4 vs 44.8%), acute kidney injury (44.7 vs 22.4%) and hospital acquired pneumonia (47.4 vs 27.6%) developed in patients receiving peramivir initially. There was no difference of median duration of use of antiviral agents between two groups (10 days in both groups). More triple combination antiviral agents were prescribed in patients initiated with oseltamivir (36.2 vs 7.9%,P=0.002) while more vasopressors (78.9 vs 44.8%, P=0.001) was used in those initiated with peramivir. There were no signifi cant differences including median length of ICU (20.5 in peramivir vs 17 days in oseltamivir, P=0.284) and 28-day mortality (36.8% [14/38] in peramivir vs 34.5% [20/58] in oseltamivir, P=0.813). Acute heart failure (Oddsratio [OR] 3.668, 95% Confi dence Interval [CI], 1.134-11.870, P=0.03), hospital acquired pneumonia (OR 4.197, 95% CI, 1.578-11.161, P=0.004) and use of corticosteroid (OR 3.022, 95% CI, 1.169-7.812, P=0.022) were associated with 28-day mortality. Conclusions: Peramivir may be an optional antiviral agent to treat the critically ill patients with severe in uenza infection and hospitalized to ICU.
Characteristics of (Fe, M)S<sub>2</sub> (M=Co, Ni, Mo) Composite Powders Fabricated by MCP
Jung, Woo Hyun,Park, Dong Kyu,Jung, Kwang Chul,Suck, Se Hoon,Ahn, In Sup,Kim, Ki Won Trans Tech Publications, Ltd. 2007 Materials science forum Vol.534 No.-
<P>As the electrodes of secondary battery are made with sulfide composite powders, excellent electrode system of environmental non-toxicity and with high specific energy density and low material cost can be obtained. In this study, the (Fe, M)S2 composite powders was synthesized by mechanochemical processes (MCP) in order to improve of the cycle life in bettery. The formation of pyrite phase appreared at the case which adds nickel, but it was not observed in the case where the transition metal was does not add but the transition metal such as cobalt, molybdenum was added in stead. From charge-discharge test results, the initial discharge capasity of (Fe, Ni)S2 electrode was 845 mAh/g. The initial discharge capasity of (Fe, Co)S2 electrode was 500mAh/g, but it showed a better cycle perfoemance than the case where the diffrent transition metal was added.</P>
( Jung Wan Yoo ),( Sang Ho Choi ),( Jin Won Huh ),( Chae Man Lim ),( Youn Suck Koh ),( Sang Bum Hong ) 대한결핵 및 호흡기학회 2014 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.118 No.-
Background: Peramivir, intravenous neuraminidase inhibitor, is available to treat influenza in hospitalized patients in South Korea. Whether it provides clinical benefits to the critically ill patients with severe influenza infection admitted to intensitve care unit (ICU)compared to oral oseltamivir remains unclear. Methods: From August 2009 through March 2014, Patients = 18 confirmed with laboratory evidence of influenza infection and hospitalized to medical ICU more than 24 hours were enrolled at Asan Medical Center. Study was performed retrospectively Results: Ninety six patients were enrolled; 38 and 58 received peramivir and oseltamivir initially, respectively. SOFA score was higher in patients initiated with peramivir. More clinical complications including shock (68.4 vs 44.8%), acute kidney injury (44.7 vs 22.4%) and hospital acquired pneumonia (47.4 vs 27.6%) developed in patients receiving peramivir initially. There was no difference of median duration of use of antiviral agents between two groups (10 days in both groups). More triple combination antiviral agents were prescribed in patients initiated with oseltamivir (36.2 vs 7.9%, P=0.002) while more vasopressors (78.9 vs 44.8%, P=0.001) was used in those initiated with peramivir. There were no significant differences including median length of ICU (20.5 in peramivir vs 17 days in oseltamivir, P=0.284) and 28-day mortality (36.8% [14/38] in peramivir vs 34.5% [20/58] in oseltamivir, P=0.813). Acute heart failure (Odds ratio [OR] 3.668, 95% Confidence Interval [CI], 1.134-11.870, P=0.03), hospital acquired pneumonia (OR 4.197, 95% CI, 1.578-11.161, P=0.004) and use of corticosteroid (OR 3.022, 95% CI, 1.169-7.812, P=0.022) were associated with 28-day mortality. Conclusions: Peramivir may be an optional antiviral agent to treat the critically ill patients with severe influenza infection and hospitalized to ICU.
박정우 ( Jung Woo Park ),이장영 ( Jang Young Lee ),이원석 ( Won Suck Lee ),성원영 ( Won Young Sung ),서상원 ( Sang Won Seo ),양중일 ( Jung Il Yang ) 대한외상학회 2014 大韓外傷學會誌 Vol.27 No.4
Purpose: Detection and determination of tendon injury in the finger or hand is not easy. Therefore, we aimed to study and evaluate the accuracy and the effectiveness of ultrasonography for the diagnosis of finger tendon injury. Methods: In this study, we enrolled patients, regardless of age and sex, with lacerations on their fingers. Patients with invisible wounds were excluded. We evaluated the accuracy and the effectiveness of ultrasonography and compared the results obtained from ultrasonography and with those obtained by visual observation of the injuries. Results: The sensitivity, the specificity and the accuracy of ultrasonography were found to be 66.7%, 100% and 91.3%, respectively (p<0.001) while those of physical examination were 71.4%, 98.3% and 91.3%, respectively. Small differences were observed between the sensitivities and specificities of the two examinations; however, the accuracies were the same (p<0.001). The area under the receiver operating characteristic (ROC) curve, which was used for diagnosis of tendon rupture using ultrasonography, was found to be 0.985 (95% confidence interval CI: 0.929-0.999),while that of physical examination was 0.938 (95% CI: 0.861-0.980). Conclusion: Ultrasonography can be used an effective diagnostic tool for patients with finger tendon injury. [ J Trauma Inj 2014; 27: 139-44 ]