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Keon Woo Park,Young-Hyuc kIm,이지연,Eungho Kim,Hyuk Lee,Bong Geun Song,Joon Oh Park,Kihyun Kim,정철원,Young Suk Park,Won Ki Kang,Mark H. Lee,Keunchil Park 대한암학회 2003 Cancer Research and Treatment Vol.35 No.5
uncommon and typically occurs in patients with disseminated diseases. This may cause difficulty in differentiating it from primary gastric carcinoma. The correct diagnosis of the primary source is important, since the treatment and prognosis of metastatic breast cancer is quite different from those of metastatic gastric cancer. Immunohistochemical staining with GCDFP-15 (gross cystic disease fluid protein-15) can be used to differentiate primary gastric carcinoma and gastric metastasis from breast cancer. We report two cases of gastric metastasis of breast cancer by describing their clinical course, illustrating the histologic findings, and showing the results of immunohistochemical staining with GCDFP-15. (Cancer Res Treat. 2003;35:460-464)
( Won-tae Cho ),( Jae-woo Cho ),( Jinil Kim ),( Jin-kak Kim ),( Jong-keon Oh ),( Hak Jun Kim ),( Namryeol Kim ),( Jun-min Cho ) 대한외상학회 2016 大韓外傷學會誌 Vol.29 No.4
Purpose: The major pelvic trauma results in high mortality with associated fatal other injuries. During early stage of resuscitation, multidisciplinary approach is essential to improve the survival and outcomes. This study aims to report the effect and positive outcome of the trauma team approach on the management of hemodynamically unstable pelvic bone fracture. Methods: This retrospective review included all patients with hemodynamically unstable pelvic bone fracture admitted between March 2007 and December 2015. Patients were divided into group A, which comprised those admitted before the trauma team approach was started, and group B, which comprised those admitted after the approach was started. The advanced trauma life support protocol was followed for all patient. The comparisons between the two groups were based on medical records. Study variables included demographics, initial vital sign, injury severity score, fracture type, and injury mechanism. We analyzed the outcomes in each group with respect to the time interval for doctors` arrival, total length of stay in the emergency department (ED), time interval for computed tomography evaluation, 24-hour mortality, time interval for definitive fixation, and definitive fixation in the time-window of opportunity. Results: Fifty-three patients met the inclusion criteria. No statistically significant differences in demographic data existed between the two groups. The time interval for doctors` arrival (min, 63.09±50.48 vs 21.48±17.75; p=0.038) and total length of stay in the ED (min, 269.33±105.96 vs 115.49±56.24; p=0.023) were significantly improved. The 24-hour mortality was not significantly different between the two groups.(%, 14.3 vs 12.0; p=1.000) However, the time interval for definitive fixation and definitive fixation in the time-window of opportunity showed better results. Conclusion: The trauma team approach has positive effects, which include initial resuscitation through multidisciplinary approach and shortening the time interval to definitive fixation, on the management of hemodynamically unstable pelvic bone fracture. [ J Trauma Inj 2016; 29: 139-145 ]
Oh, So Yeon,Shin, Sang Won,Koh, Su-Jin,Bae, Sang Byung,Chang, Hyun,Kim, Jung Han,Kim, Hyo Jung,Hong, Young Seon,Park, Keon Uk,Park, Jeanno,Lee, Kyung Hee,Lee, Na Ri,Lee, Jung Lim,Jang, Joung Soon,Hong Springer Berlin Heidelberg 2017 SUPPORTIVE CARE IN CANCER Vol.25 No.12
<P><B>Purpose</B></P><P>Neuropathic cancer pain (NCP) is a common and potentially debilitating symptom in cancer patients. We investigated the prevalence of NCP, as well as its management and association with QOL.</P><P><B>Methods</B></P><P>Cancer patients with pain ≥1 on the visual analogue scale (VAS) were surveyed with the Douleur Neuropathique (DN4) questionnaire, the Brief Pain Inventory-Short Form (BPI-SF), and the EuroQOL five dimensions (EQ-5D) questionnaire. The associations between NCP and pain severity or NCP and QOL, while controlling for variables relevant to QOL, were then analyzed.</P><P><B>Results</B></P><P>A total of 2003 patients were enrolled in this survey; the prevalence of NCP was 36.0% (<I>n</I> = 722, 95% CI, 32.5–39.5). We found that NCP in cancer patients was closely correlated to a higher pain severity (BPI-SF; 4.96 ± 1.94 versus 4.24 ± 2.02, <I>p</I> < 0.001), and in patients with NCP, pain more severely interfered with daily living, as compared to those without NCP (BPI-SF; 4.86 ± 2.71 versus 4.41 ± 2.87, <I>p</I> < 0.001). Patients with NCP also had worse QOL than those without NCP, as measured by EQ-5D index score (0.47 ± 0.30 vs. 0.51 ± 0.30, <I>p</I> = 0.005), and this was confirmed using multivariate analysis (<I>p</I> < 0.001), even after controlling for other variables such as age, sex, disease stage, cancer duration, radiotherapy, chemotherapy, and comorbidities. Importantly, adjuvant analgesics were used in less than half of patients with NCP (<I>n</I> = 358, 46.4%).</P><P><B>Conclusions</B></P><P>We found that NCP in cancer patients was significantly associated with a worsened QOL, and current management is inadequate. Therefore, future research aimed at developing improved strategies for management of NCP is required.</P><P><B>Electronic supplementary material</B></P><P>The online version of this article (doi:10.1007/s00520-017-3806-5) contains supplementary material, which is available to authorized users.</P>
미국중재협회/국제분쟁해결센터(AAA/ICDR)의 긴급중재인 제도에 관한 연구
안건형(Keon-hyung Ahn),이동수(Michael Lee),오원석(Won-suk Oh) 한국국제상학회 2011 國際商學 Vol.26 No.2
In the past, there was no option for a party to the arbitration to apply an interim relief to the competent court before the arbitral tribunal was constituted. To solve this problem, the ICDR, among all the arbitration institutions throughout the world, had firstly introduced the emergency arbitrator procedure by adding an article 37 in its International Arbitration Rules (hereinafter referred to “ICDR Rules”) on 1 May, 2006. The purpose of this paper is to draw attention on the necessity and importance of emergency arbitrator system by examining four decisions rendered by emergency arbitrators at the ICDR related to emergency interim relief and a number of case laws ruling on the interim relief by the US courts.
Neuro-Fuzzy 기법을 이용한 부분방전 패턴인식에 대한 연구
朴建俊(Keon-Jun Park),金吉成(Gil-Sung Kim),吳聖權(Sung-Kwun Oh),崔源(Won Choi),金正泰(Jeong-Tae Kim) 대한전기학회 2008 전기학회논문지 Vol.57 No.12
In order to develop reliable on-site partial discharge(PD) pattern recognition algorithm, the fuzzy neural network based on fuzzy set (FNN) and the polynomial network pattern classifier based on fuzzy Inference (PNC) were investigated and designed. Using PD data measured from laboratory defect models, these algorithms were learned and tested. Considering on-site situation where it is not easy to obtain voltage phases in PRPDA(Phase Resolved Partial Discharge Analysis), the measured PD data were artificially changed with shifted voltage phases for the test of the proposed algorithms. As input vectors of the algorithms, PRPD data themselves were adopted instead of using statistical parameters such as skewness and kurtotis, to improve uncertainty of statistical parameters, even though the number of input vectors were considerably increased. Also, results of the proposed neuro-fuzzy algorithms were compared with that of conventional BP-NN (Back Propagation Neural Networks) algorithm using the same data. The FNN and PNC algorithms proposed in this study were appeared to have better performance than BP-NN algorithm.
Sprague-Dawley계 흰 쥐에 대한 발효녹용 추출물의 항피로 효과
정원석 ( Won Suk Chung ),김성수 ( Sung Soo Kim ),오재근 ( Jae Keon Oh ),이준환 ( Jun Hwan Lee ),김고운 ( Koh Woon Kim ),조융기 ( Yoong Ki Jo ),연창호 ( Chang Ho Yeon ),이종수 ( Jong Soo Lee ) 한방재활의학과학회 2012 한방재활의학과학회지 Vol.22 No.1
목적 : 이 연구는 Sprague-Dawley계 흰 쥐에 대한 발효녹용 추출물의 항근피로 효과를 관찰하는 것을 목적으로 하였다. 방법 : 한 군 당 10마리의 쥐를 각각 4개의 군으로 무작위 배정했다. 대조군에게는 생리식염수를 투여하였고, 양성대조군에게는 100 mg/kg 용량의 녹용 물추출물을, 실험군 1에게는 50 mg/kg 용량의 발효녹용 추출물을, 실험군 2에게는 100 mg/kg 용량의 발효녹용 추출물을 각각 투여하였다. 7일 간의 투여 이후, 4개의 군은 각각 high intensity exercise model과 prolonged exercise model를 개량한 강제 유영 실험을 거쳤다. 그 이후에, 유영 시간 및 혈액화학적 지표를 관찰하였다. 결과 : High intensity exercise model을 개량한 강제 유영 실험에서, 녹용은 용량의존적으로 유영 시간을 연장시켰다. 실험군 2는 대조군과 비교해서 약 600% 긴 유영 시간을 나타냈다(p<0.001). Prolonged exercise model을 개량한 강제 유영 실험에서는, 혈당(p<0.001)과 유리지방산(p<0.05, p<0.01)이 대조군에 비해 양성대조군과 실험군 1, 2에서 모두 유의한 회복효과를 나타냈다. 결론 : 발효녹용 추출물은 녹용의 물추출물과 유사한 항근피로효과를 나타냈으며, 수율을 감안하면 녹용 물추출물의 1/5에 해당하는 용량으로 같은 정도의 효과를 낼 수 있을 것으로 사료된다. Objectives :The aim of this study was to investigate the Anti-muscle fatigue effect of fermented deer velvet antler extract in Sprague-Dawley rats. Methods : Rats were randomly divided into four groups of 10 mice each according to a randomized block design. Saline solution was orally administered to the control group, 100 mg/kg of water-extract of deer velvet antler to the positive control group, 50 mg/kg of fermented deer velvet antler extract to experimental group 1 and 100 mg/kg of fermented deer velvet antler extract to experimental group 2. Each of the four groups were treated for seven days and then participated in a forced swimming test which applied both a high intensity exercise model and a prolonged exercise model. We observed swimming times and examined blood biochemical parameters. Results : In the high intensity exercise model, the effect of the deer velvet antler was seen in the increased swimming times. Experimental group 2 swam for approximately 600% longer as compared to the control group(p<0.001), indicating that the recovery effect is dose-dependent. In the forced swimming tests using the prolonged exercise model, blood sugar levels(p<0.001) and free fatty acid levels(p<0.05, p<0.01 each) in the positive control group and experimental groups 1 and 2 demonstrated a significant recovery effect in comparison with the control group. Conclusions : Fermented deer velvet antler extract may have an Anti-muscle fatigue effect similar to that of deer velvet antler extract and could be used when it has an effect equal to one-fifth of the amount considering the yield rate.