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김병호 ( Byung Ho Kim ),감신 ( Sin Kam ),배상근 ( Sang Geun Bae ),김건엽 ( Keon-yeop Kim ),이원기 ( Won Kee Lee ),홍남수 ( Nam-soo Hong ),박형근 ( Hyeung-keun Park ),이혜진 ( Heyjean Lee ),조은정 ( Eun-jung Cho ),채성철 ( Shung C 한국보건정보통계학회(구 한국보건통계학회) 2017 보건정보통계학회지 Vol.42 No.1
Objectives: This study was conducted to investigate economic feasibility of operating Regional Cardiocerebrovascular Centers using cost-benefit analysis. Methods: The current study assessed cost and benefit data collected from nine hospitals which were designated as Regional Cardiocerebrovascular Centers between 2008 and 2010. Results: The operation of Regional Cardiocerebrovascular Centers reduced mortality rate and length of stay due to acute myocardial infarction and stroke and also decreased disability occurred after stroke. The total calculated cost of operating nine Regional Cardiocerebrovascular Centers was 19.85-22.30 billion won and the minimum benefit calculated was 23.98 billion won. Applying the maximum cost and the minimum benefit, the net benefit was 1.68 billion won, which is estimated to 190 million won per Regional Cardiocerebrovascular Center. Conclusions: The present study revealed that the operation of Regional Cardiocerebrovascular Centers was economically beneficial. The benefit would be larger if intangible benefit such as the long-term effects to community hospitals and enhancement of quality of life of patients and their families are considered.
Lee, Geumho,Choi, Tae Won,Kim, Chulwon,Nam, Dongwoo,Lee, Seok-Geun,Jang, Hyeung-Jin,Lee, Jun-Hee,Um, Jae-Young,Jung, Sang Hoon,Shim, Bum Sang,Ahn, Kyoo Seok,Ahn, Kwang Seok Informa Healthcare 2012 Immunopharmacology and immunotoxicology Vol.34 No.3
<P><I>Reynoutria elliptica</I> has been used in traditional Korean medicine to promote blood circulation, relieve pain, increase dieresis, and alleviate respiratory problems, through as yet undefined mechanisms. We set out to determine whether the anti-inflammatory effects of this plant are linked with its ability to suppress mitogen-activated protein kinases (MAPKs) and nuclear factor-κB (NF-κB) activation in lipopolysaccharide (LPS)-activated RAW 264.7 cells. We found for the first time that the hexane fraction of <I>Reynoutria elliptica</I> (HRE) significantly inhibited LPS-stimulated NO and PGE2 synthesis. This is due to the diminishing of the mRNA and protein expression of iNOS and COX-2, respectively. HRE also suppressed LPS-stimulated TNF-α secretion in a dose-dependent manner, which might be due to the suppression of LPS-induced MAPKs and NF-κB activation. Moreover, our HPLC data demonstrated that the major components of the HRE were bioactive compounds such as emodin-6-Glc, emodin, and physcion. Overall, our results indicate that <I>Reynoutria elliptica</I> could be provided as a potential candidate for anti-inflammation treatment.</P>
An FE Based On-line Model for the Prediction of Work Roll Thermal Profile in Hot Strip Rolling
Ji Won Choi,Jung Hyeung Lee,Cheng Gang Sun,Sang Moo Hwang 한국소성가공학회 2010 기타자료 Vol.2010 No.6
Prediction and control of the thermal deformation of the work roll is vital for enhancing product quality in hot strip and plate rolling. In this paper, we present an on-line model for the prediction of the work roll thermal profile. The model is developed on the basis of an integrated finite element model for the coupled analysis of heat transfer and deformation occurring at the bite zone, to rigorously take into account the effect of various rolling parameters on the thermal behavior of the work roll. The validity of the model is demonstrated through comparison with measurements made in an industrial hot strip mill. Also, an emphasis is given to the examination the effect of some selected rolling parameters in an actual production environment.
시뮬레이션을 이용한 금융 ATM기 유지보수의 효율적 운영에 관한 연구
유형근(Hyeung Keun Yu),이강원(Kang Won Lee) 한국경영과학회 2011 經營 科學 Vol.28 No.1
The automated teller machine (ATM) is developed as a system to provide customers with an easy deposit and withdrawal of their money without time restriction and be served for 24 hours. Today, ATM is come up to the level of an unmanned branch. The automatic financing system is developed as an essential one for dealing with the rationalization of management and the globalization of financing in order to improve the efficiency of financial management work and increase the customer service quality. With reducing the operational cost of financial organizations through the efficient maintenance operation of ATM and increasing the service quality through the maximization of its processing efficiency, this study is to draw the scheme to ensure the competitiveness among the finance companies. The importance of ATM is highly recognized as the utilization of ATM is increased and the processing function is extended, but ATM is quite vulnerable to the malfunction occurred during the nighttime after banking hours. The ATM maintenance is done through consignment to the specialized maintenance company. The efficient operation of ATM maintenance work is important to the satisfaction of customer using ATM in the nighttime.