Continuous Conversion of Rice Starch Hydrolysate to 2-keto-D-gluconic Acid by Arthrobacter globiformis C224

Wen-Hua Teng,Wen-Jing Sun,Bin Yu,Fengjie Cui,Jing-Ya Qian,Jingze Liu,Liang Wang,Xiang-Hui Qi,Hua Wei 한국생물공학회 2013 Biotechnology and Bioprocess Engineering Vol.18 No.4

A continuous conversion process of rice starch hydrolysate to 2-keto-D-gluconic acid (2KGA) by Arthrobacter globiformis C224 was developed. Its feasibility for industrial application was also evaluated. Results showed that the initial cell concentration exceeding 1.25 g/L met the continuous 2KGA production at a stable dilution rate and media composition, while the dilution rate and feeding glucose concentration had a significant effect on 2KGA production performance. The optimal operating parameters were obtained as: 0.090/h of dilution rate and 171.0 g/L of feeding glucose concentration. Under these conditions, the steady state had a produced 2KGA concentration of 124.74 g/L, average volumetric productivity of 11.23 g/L/h,and yield of 0.97 g/g. In conclusion, continuous 2KGA production by the A. globiformis C224 strain would be a superior industrial process for the production of 2KGA in terms of its high 2KGA productivity and yield.

Prediction Models for Solitary Pulmonary Nodules Based on Curvelet Textural Features and Clinical Parameters

Wang, Jing-Jing,Wu, Hai-Feng,Sun, Tao,Li, Xia,Wang, Wei,Tao, Li-Xin,Huo, Da,Lv, Ping-Xin,He, Wen,Guo, Xiu-Hua Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.10

Lung cancer, one of the leading causes of cancer-related deaths, usually appears as solitary pulmonary nodules (SPNs) which are hard to diagnose using the naked eye. In this paper, curvelet-based textural features and clinical parameters are used with three prediction models [a multilevel model, a least absolute shrinkage and selection operator (LASSO) regression method, and a support vector machine (SVM)] to improve the diagnosis of benign and malignant SPNs. Dimensionality reduction of the original curvelet-based textural features was achieved using principal component analysis. In addition, non-conditional logistical regression was used to find clinical predictors among demographic parameters and morphological features. The results showed that, combined with 11 clinical predictors, the accuracy rates using 12 principal components were higher than those using the original curvelet-based textural features. To evaluate the models, 10-fold cross validation and back substitution were applied. The results obtained, respectively, were 0.8549 and 0.9221 for the LASSO method, 0.9443 and 0.9831 for SVM, and 0.8722 and 0.9722 for the multilevel model. All in all, it was found that using curvelet-based textural features after dimensionality reduction and using clinical predictors, the highest accuracy rate was achieved with SVM. The method may be used as an auxiliary tool to differentiate between benign and malignant SPNs in CT images.

Serum Zinc Status and Helicobacter Pylori Infection in Gastric Disease Patients

Zhang, Wen-Hua,Wu, Xiao-Jing,Niu, Jing-Xiu,Yan, Hao,Wang, Xin-Zhuo,Yin, Xiao-Dong,Pang, Yan Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.10

The role of Helicobacter pylori status and serum zinc value in gastric disease patients and healthy controls were investigated. Cases used in this work were 45 gastric cancer patients, 44 with peptic ulcers, 52 suffering gastritis and 64 healthy controls, all diagnosed histologically with the controls undergoing medical checkups. Helicobacter pylori status and serum levels of Zn were determined by 13C-urea breath test and flame atomic absorption spectrophotometer, respectively. Our study showed that Helicobacter pylori infection has no change in gastritis, peptic ulcer and gastric cancer group, on the contrast, serum levels of Zn were significantly reduced in gastritis, peptic ulcer and gastric cancer group, compared with healthy controls, and the higher the Zn levels are, the more increased risk of gastric cancer. Helicobacter pylori infection is a cause of gastritis, peptic ulcers and even gastric cancer, while serum zinc level is an indicator of protection of gastric membranes against damage.

Bond-slip Constitutive Relation between BFRP Bar and Basalt Fiber Recycled-aggregate Concrete

Wen-jing Meng,Hua-xin Liu,Gen-jin Liu,Xiang-qing Kong,Xue-zhi Wang 대한토목학회 2016 KSCE JOURNAL OF CIVIL ENGINEERING Vol.20 No.5

In order to investigate the bond stress-slip constitutive relation between BFRP bar and basalt fiber recycled-aggregate concrete, 81 central pullout specimens were tested. Basalt fiber volume percent, fiber length and concrete strength grade were considered to be experimental variables to obtain the bond stress-slip curves. The results showed that adding basalt fiber into recycled-aggregate concrete will reduce the bond stress between BFRP bar and recycled-aggregate concrete but enhance the ductility of bond property; the bond stress increases with the increasing of fiber length and concrete strength grade. The bond stress-slip constitutive model was proposed and the results showed that the model is good in effect of fitting. The constitutive model can reflect the bonding mechanism between BFRP bar and basalt fiber concrete well, it also can provide reference for theoretical analysis and engineering applications of the bond and anchor property between BFRP bars strengthened recycled concrete.

Convenient hydrogel adhesion with crystalline zones

Wen-Tao Chen,Liangpeng Zeng,Ping Li,Yi Liu,Jing-Liang Huang,Hui Guo,Ping Rao,Wei-Hua Li 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.117 No.-

Adhering soft hydrogels to hard substrates is challenging. Existing adhesion approaches mainly rely oninterfacial chemical bonds or physical interactions, which typically require complex fabrication processesor specific surface properties. Herein, we report a convenient approach to achieving effective hydrogeladhesion onto various hard substrates with in-situ formed crystalline zones by heating. Semicrystallizablepoly(vinyl alcohol) hydrogels were directly cast on various subtracts by a dryingswellingprocess, which demonstrates strong adhesion with adhesion energy as high as 890 J/m2. Theadhesion performance demonstrates an obvious positive correlation with the crystalline property. Therefore, the factors determining the crystalline degree, including the polymer type and preparationtemperature, demonstrate remarkable influences on the adhesion performance. Moreover, this adhesionperformance manifests high durability in harsh environments. Benefitting from the strong and durableadhesion performance, the crystalline gels can serve as a tie coating layer to joint various hydrogels,which demonstrate satisfactory antifouling ability. Therefore, this strategy may endow the materials withgreat potential for various practical applications in the future.

Analysis of fourth-grade fluid model over a stretchable surface with Riga plate subject to permeable medium

Hua Bian,Shah Faisal,Khan M Ijaz,El-Zahar Essam Roshdy,Farooq Shahid,Khan Sami Ullah,Guedri Kamel,Wu Wen-jing 한국CDE학회 2022 Journal of computational design and engineering Vol.9 No.3

The current investigation is concerned with the rheological impact of fourth-grade confined by Riga surface. The flow behaviour is analysed over a Riga plate in the presence of stagnation point and porous medium. The relevant similarity variables and corresponding boundary conditions are adopted to model the current problem. The highly non-linear coupled differential system is via optimal homotopy scheme. The outcomes of relevant dimensionless parameters on the velocity profile have been visualized with physical exploration. It is observed from the obtained outcomes that the fluid velocity declines against rising estimations of modified magnetic variable and inverse Darcy number. The increasing velocity change is noted for boosting values of third-grade fluid parameter. Moreover, the velocity pattern for fourth-grade material is comparatively higher than viscous, second-grade, and third-grade materials. The comparative analysis against obtained simulations is also listed.

Air Injection System Design Based On Critical Pore-Gas Velocity for Landfill Aeration

( Hua-yong Wu ),( Hong-tao Wang ),( Wen-jing Lu ),( Tan Chen ) 한국폐기물자원순환학회 2011 ISWA Vol.2011 No.0

LETTER TO THE EDITOR : One Mutation of the ED1 Gene in a Chinese Han Family with X-Linked Hypohidrotic Ectodermal Dysplasia

( Jing Wang ),( Wei Wei Ha ),( Wen Wang ),( Hua Yang Tang ),( Xian Fa Tang ),( Xian Dong Zheng ),( Jun Zhu ),( Xian Yong Yin ),( Sen Yang ),( Xue Jun Zhang ) 대한피부과학회 2014 Annals of Dermatology Vol.26 No.1

Phytochemistry and pharmacology of natural prenylated flavonoids

Hua-Wei Lv,Qiao-Liang Wang,Meng Luo,Meng-Di Zhu,Hui-Min Liang,Wen-Jing Li,Hai Cai,Zhong-Bo Zhou,Hong Wang,Sheng-Qiang Tong,Xing-Nuo Li 대한약학회 2023 Archives of Pharmacal Research Vol.46 No.4

Prenylated flavonoids are a special kind of flavonoid derivative possessing one or more prenyl groups in the parent nucleus of the flavonoid. The presence of the prenyl side chain enriched the structural diversity of flavonoids and increased their bioactivity and bioavailability. Prenylated flavonoids show a wide range of biological activities, such as anti-cancer, anti-inflammatory, neuroprotective, anti-diabetic, anti-obesity, cardioprotective effects, and anti-osteoclastogenic activities. In recent years, many compounds with significant activity have been discovered with the continuous excavation of the medicinal value of prenylated flavonoids, and have attracted the extensive attention of pharmacologists. This review summarizes recent progress on research into natural active prenylated flavonoids to promote new discoveries of their medicinal value.

Endovascular Treatment for Iliac Vein Compression Syndrome: a Comparison between the Presence and Absence of Secondary Thrombosis

Wen-Sheng Lou,Jian-Ping Gu,Xu He,Liang Chen,Hao-Bo Su,Guo-Ping Chen,Jing-Hua Song,Tao Wang 대한영상의학회 2009 Korean Journal of Radiology Vol.10 No.2

Objective: To evaluate the value of early identification and endovascular treatment of iliac vein compression syndrome (IVCS), with or without deep vein thrombosis (DVT). Materials and Methods: Three groups of patients, IVCS without DVT (group 1, n = 39), IVCS with fresh thrombosis (group 2, n = 52) and IVCS with non-fresh thrombosis (group 3, n = 34) were detected by Doppler ultrasonography, magnetic resonance venography, computed tomography or venography. The fresh venous thrombosis were treated by aspiration and thrombectomy, whereas the iliac vein compression per se were treated with a self-expandable stent. In cases with fresh thrombus, the inferior vena cava filter was inserted before the thrombosis suction, mechanical thrombus ablation, percutaneous transluminal angioplasty, stenting or transcatheter thrombolysis. Results: Stenting was performed in 111 patients (38 of 39 group 1 patients and 73 of 86 group 2 or 3 patients). The stenting was tried in one of group 1 and in three of group 2 or 3 patients only to fail. The initial patency rates were 95% (group 1), 89% (group 2) and 65% (group 3), respectively and were significantly different (p = 0.001). Further, the six month patency rates were 93% (group 1), 83% (group 2) and 50% (group 3), respectively, and were similarly significantly different (p = 0.001). Both the initial and six month patency rates in the IVCS patients (without thrombosis or with fresh thrombosis), were significantly greater than the patency rates of IVCS patients with non-fresh thrombosis. Conclusion: From the cases examined, the study suggests that endovascular treatment of IVCS, with or without thrombosis, is effective. Objective: To evaluate the value of early identification and endovascular treatment of iliac vein compression syndrome (IVCS), with or without deep vein thrombosis (DVT). Materials and Methods: Three groups of patients, IVCS without DVT (group 1, n = 39), IVCS with fresh thrombosis (group 2, n = 52) and IVCS with non-fresh thrombosis (group 3, n = 34) were detected by Doppler ultrasonography, magnetic resonance venography, computed tomography or venography. The fresh venous thrombosis were treated by aspiration and thrombectomy, whereas the iliac vein compression per se were treated with a self-expandable stent. In cases with fresh thrombus, the inferior vena cava filter was inserted before the thrombosis suction, mechanical thrombus ablation, percutaneous transluminal angioplasty, stenting or transcatheter thrombolysis. Results: Stenting was performed in 111 patients (38 of 39 group 1 patients and 73 of 86 group 2 or 3 patients). The stenting was tried in one of group 1 and in three of group 2 or 3 patients only to fail. The initial patency rates were 95% (group 1), 89% (group 2) and 65% (group 3), respectively and were significantly different (p = 0.001). Further, the six month patency rates were 93% (group 1), 83% (group 2) and 50% (group 3), respectively, and were similarly significantly different (p = 0.001). Both the initial and six month patency rates in the IVCS patients (without thrombosis or with fresh thrombosis), were significantly greater than the patency rates of IVCS patients with non-fresh thrombosis. Conclusion: From the cases examined, the study suggests that endovascular treatment of IVCS, with or without thrombosis, is effective.