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Weihua Li,Yipeng Wang,Junlong Guo,Dianbo Ren,Jianfeng Wang,Shengkai Zhu,Jianping Xiao,Shijuan Chen 제어·로봇·시스템학회 2023 International Journal of Control, Automation, and Vol.21 No.5
This study proposes an improved artificial potential field (APF) by considering the cooperative control of local obstacle avoidance and path tracking for automated vehicles. We established the path gravitational potential field (GPF) based on the scheduled path (SP), including the lateral and longitudinal GPFs, to enable the automated vehicle to quickly return to the SP and track after obstacle avoidance, while maintaining control of speed for the entire process. To address the local optimal solution problem of the classical APF, we proposed a sub-target-point selection strategy based on the information of obstacles and SP and established the GPF of the sub-target points. Thus, the automated vehicle can avoid obstacles and quickly return to the SP. Furthermore, the relative velocity of the automated vehicle and the obstacle was used to establish the velocity repulsion potential field (RPF), which improved the adaptability of the APF to dynamic obstacles. The simulation results indicate that the improved APF is capable of cooperative control of path tracking and local obstacle avoidance. Code is available at https://github.com/xiaowang617/Improve-APF.
Huixia Zhu,Shiru Jia,Hongjiang Yang,Weihua Tang,Zhilei Tan,Yuanyuan Jia 한국식품과학회 2010 Food Science and Biotechnology Vol.19 No.6
The feasibility of a novel bacteriostatic sausage casing made of bacterial cellulose (BC) embedded with ε-polylysine (ε-PL) was evaluated. The ε-PL/BC composite was prepared by immersing BC tubes in ε-PL solution and its characteristics were analyzed with Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD),and atomic force microscopy (AFM) techniques, respectively. The results suggested that ε-PL molecules were incorporated into the cellulose fiber networks and the ε-PL/BC composite might have a novel unique structure. No significant loss of antimicrobial activity was observed even after autoclaving at 121℃ for 30 min and the oxygen permeability was far below than that of polyethylene (PE) and polyvinyl alcohol (PVA) membrane. Its tensile strength was 51.8 MPa. The ε-PL/BC composite exhibits bacteriostatic and/or bacteriocidal activities against a broad spectrum of Gram-positive and Gram-negative bacteria; as a result, an extended shelf life than controls was observed for sausage packaged with the ε-PL/BC composite.
Xiaodan Zhu,Fanglei Ye,Shaojuan Hao,Qiuning Yu,Yang Wang,Weihua Lou,Kun Zhao,Hongmin Li 한국생물공학회 2022 Biotechnology and Bioprocess Engineering Vol.27 No.1
Cholesteatoma is a pathologically benign but clinically destructive middle ear disease characterized by hyperproliferative keratinocytes. B-cell-specific Moloney murine leukemia virus insertion site 1 (BMI1) has been reported to be upregulated in cholesteatoma tissues. This study aimed to explore the biological role and underlying mechanisms of BMI1 in the progression of cholesteatoma. The expression levels of microRNA (miR)-1297, miR-26a- 5p, and BMI1 in cholesteatoma tissues and cells were examined by quantitative real-time polymerase chain reaction (qRT-PCR) or western blot. Functional experiments were performed by CCK-8 assay for cell proliferation viability, 5-ethynyl-2'deoxyuridine (EdU) incorporation assay for DNA biosynthesis, colony formation assay for cloning forming ability analysis, transwell assay and wound healing assay for cell metastasis, flow cytometry for cell cycle distribution and cell apoptosis. The protein expression of apoptosis-associated proteins was investigated by western blot. Dual-luciferase reporter assay was conducted to verify the interaction between miR-1297 or miR-26a-5p and BMI1. BMI1 was highly expressed in cholesteatoma tumor tissues. Functional analyses showed that BMI1 knockdown could inhibit the proliferation, colony formation, migration, invasion, cell cycle progression and promoted the apoptosis of keratinocytes. Mechanically, BMI1 was a target of miR-1297 and miR-26a-5p. Moreover, the rescue experiments presented that BMI1 addition could abolish the suppressive effects of miR-1297 or miR-26a-5p overexpression on cell malignant behaviors in keratinocytes. BMI1 could exert an oncogenic role in the malignant development of cholesteatoma through serving as the targets of miR-1297 and miR-26a-5p, which might provide novel strategies for cholesteatoma treatment.
Wang, Weihua,Feng, Wuwei,Yuan, Jiangyan,Pang, Ning,Zhao, Xiaoxue,Li, Meiyun,Bao, Zhidi,Zhu, Kun,Odkhuu, Dorj Elsevier 2018 PHYSICA B-CONDENSED MATTER - Vol.540 No.-
<P><B>Abstract</B></P> <P>Double perovskite La<SUB>2</SUB>Fe<SUB>2-x</SUB>Co<SUB>x</SUB>O<SUB>6</SUB> was prepared and studied. Orthorhombic and trigonal structures were obtained depend on the molar ratio of Fe to Co. Fe-rich sample demonstrate ferrimagnetic properties; with increasing content of Co, trigonal structure is favored and the net magnetic moment of sample decrease gradually to zero. Our experimental results were further supported by first-principle theoretical calculations and demonstrate that La<SUB>2</SUB>Fe<SUB>2-x</SUB>Co<SUB>x</SUB>O<SUB>6</SUB> is a new high <I>T</I> <SUB> <I>c</I> </SUB> ferromagnetic semiconductor with tunable magnetic properties and is thus a promising material for spintronics devices.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Phase-pure double perovskite La2Fe2-xCoxO6 was prepared. </LI> <LI> Orthorhombic and trigonal structures were obtained depending on the ratio of Fe to Co. </LI> <LI> La2Fe2-xCoxO6 is a new high Tc ferromagnetic semiconductor with tunable magnetic properties. </LI> <LI> Theoretical ab initio calculations further support our experimental results. </LI> </UL> </P>
Bias process for heteroepitaxial diamond nucleation on Ir substrates
Wang Weihua,Yang Shilin,Liu Benjian,Hao Xiaobin,Han Jiecai,Dai Bing,Zhu Jiaqi 한국탄소학회 2023 Carbon Letters Vol.33 No.2
Heteroepitaxy is a better method of enlarging SCD wafer size than homoepitaxy. In this work, several aspects of the bias process for heteroepitaxial diamond nucleation are studied experimentally. First, with increasing bias time, the diamond-nucleation pathway is found to transform from “isolated-crystal nucleation” to “typical domain-nucleation” and back to “isolated-crystal nucleation.” An interdependent relationship between bias voltage and bias time is proposed: the higher the bias voltage, the shorter the bias time. Second, a correlation exists between the threshold bias voltage and reactor-chamber pressure: a higher reactor chamber pressure usually requires a higher threshold bias voltage to realize “typical domain nucleation.” Third, diamond bias-enhanced nucleation and growth is observed at a high CH4 content, where the dynamic equilibrium between amorphous-carbon-layer deposition and atomic-hydrogen etching is broken. Finally, epitaxial nucleation is obtained on a substrate with ∅30 mm in a home-made MPCVD setup.
Conduction Mechanism in (La0.7Sr0.3MnO3)n(BiFeO3)n Multilayered Thin Films
Huiwen Zhu,Shunli Wang,Ping Jiang,Jingqin Shen,Weihua Tang 한국물리학회 2010 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.57 No.2
(La0.7Sr0.3MnO3)n(BiFeO3)n multilayered thin films were deposited on (0 0 1) SrTiO3 substrates by using the RF magnetron sputtering method, and their conduction mechanisms in the temperature range between 150 K and 300 K were investigated using several common dielectric conduction models. The results indicate the current-voltage characterization of the as-fabricated thin films obey Ohm’s law at 300 K, but the space-charge-limited conduction mechanism becomes dominant in the as-fabricated thin films as the temperature is decreased.
First-Principles Study of the Three Polymorphs of Crystalline 1,1-Diamino-2,2-dinitrotheylene
Wu, Qiong,Zhu, Weihua,Xiao, Heming Korean Chemical Society 2013 Bulletin of the Korean Chemical Society Vol.34 No.8
The electronic structure, optical spectra, and thermodynamic properties of the three FOX-7 polymorphs (${\alpha}$, ${\beta}$, and ${\gamma}$) have been studied systematically using density functional theory. The LDA (CA-PZ) and generalized gradient approximation (GGA) (PW91) functions were used to relax the three FOX-7 phases without any constraint. Their density of states and partial density of states were calculated and analyzed. The band gaps for the three phases were calculated and the sequence of their sensitivity was presented. Their absorption coefficients were computed and compared. The thermodynamic functions including enthalpy (H), entropy (S), free energy (G), and heat capacity ($C_p$) for the three phases were evaluated.