Traffic speed mapping with cellular network signaling data by FOSS4G

Wang Weifeng,Zhu Kemin,Liu Junli,Hu Jinghao,Raganvan Venkatesh,Xu Jiang,Song Xianfeng 대한공간정보학회 2022 Spatial Information Research Vol.30 No.1

Mapping traffic speed on road networks is crucial for urban traffic management and the development of intelligent transportation systems. Traditionally, information regarding traffic speed can be obtained from locationfixed sensors, such as loop detectors and cameras; however, these methods are limited to major road crosses. Recently, a considerable attention has been paid to utilizing vehicles with mobile phones as probes for collecting traffic information. This study proposes an open-source GIS approach to map traffic speeds in a road network. First, public service vehicles (PSVs) were identified from cellular network signaling data by measuring the similarity between cell-ID trajectories and bus routes. Then, the cell-ID trajectories of PSVs were refined into high-quality spatiotemporal trajectories, and projected onto the road network via heuristic global optimization. Finally, hourly traffic speed maps were computed by weighing the speeds of the PSVs in the road network. The approach was implemented using free and open source software for geospatial mapping stacks of toolkits (Python, TimescaleDB/PostGIS, Pandas/Pygmo2, and Matplotlib/Seaborn); this application demonstrated good results using cellular network signaling data and GPS trajectories collected in Huilongguan district, Beijing, China. Moreover, this demonstration illustrates that probe mobile monitoring is emerging as a critical technology for traffic monitoring supplements, which can help develop a comprehensive view of the roads and reduce the cost of monitoring a large area.

Traffic speed mapping with cellular network signaling data by FOSS4G

Wang Weifeng,Zhu Kemin,Liu Junli,Hu Jinghao,Raganvan Venkatesh,Xu Jiang,Song Xianfeng 대한공간정보학회 2022 Spatial Information Research Vol.30 No.2

Mapping traffic speed on road networks is crucial for urban traffic management and the development of intelligent transportation systems. Traditionally, information regarding traffic speed can be obtained from locationfixed sensors, such as loop detectors and cameras; however, these methods are limited to major road crosses. Recently, a considerable attention has been paid to utilizing vehicles with mobile phones as probes for collecting traffic information. This study proposes an open-source GIS approach to map traffic speeds in a road network. First, public service vehicles (PSVs) were identified from cellular network signaling data by measuring the similarity between cell-ID trajectories and bus routes. Then, the cell-ID trajectories of PSVs were refined into high-quality spatiotemporal trajectories, and projected onto the road network via heuristic global optimization. Finally, hourly traffic speed maps were computed by weighing the speeds of the PSVs in the road network. The approach was implemented using free and open source software for geospatial mapping stacks of toolkits (Python, TimescaleDB/PostGIS, Pandas/Pygmo2, and Matplotlib/Seaborn); this application demonstrated good results using cellular network signaling data and GPS trajectories collected in Huilongguan district, Beijing, China. Moreover, this demonstration illustrates that probe mobile monitoring is emerging as a critical technology for traffic monitoring supplements, which can help develop a comprehensive view of the roads and reduce the cost of monitoring a large area.

Cytosolic escape of mitochondrial DNA triggers cGAS-STING-NLRP3 axis-dependent nucleus pulposus cell pyroptosis

Zhang Weifeng,Li Gaocai,Luo Rongjin,Lei Jie,Song Yu,Wang Bingjin,Ma Liang,Liao Zhiwei,Ke Wencan,Liu Hui,Hua Wenbin,Zhao Kangcheng,Feng Xiaobo,Wu Xinghuo,Zhang Yukun,Wang Kun,Yang Cao 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-

Low back pain (LBP) is a major musculoskeletal disorder and the socioeconomic problem with a high prevalence that mainly involves intervertebral disc (IVD) degeneration, characterized by progressive nucleus pulposus (NP) cell death and the development of an inflammatory microenvironment in NP tissue. Excessively accumulated cytosolic DNA acts as a damage-associated molecular pattern (DAMP) that is monitored by the cGAS-STING axis to trigger the immune response in many degenerative diseases. NLRP3 inflammasome-dependent pyroptosis is a type of inflammatory programmed death that promotes a chronic inflammatory response and tissue degeneration. However, the relationship between the cGAS-STING axis and NLRP3 inflammasome-induced pyroptosis in the pathogenesis of IVD degeneration remains unclear. Here, we used magnetic resonance imaging (MRI) and histopathology to demonstrate that cGAS, STING, and NLRP3 are associated with the degree of IVD degeneration. Oxidative stress induced cGAS-STING axis activation and NLRP3 inflammasome-mediated pyroptosis in a STING-dependent manner in human NP cells. Interestingly, the canonical morphological and functional characteristics of mitochondrial permeability transition pore (mPTP) opening with the cytosolic escape of mitochondrial DNA (mtDNA) were observed in human NP cells under oxidative stress. Furthermore, the administration of a specific pharmacological inhibitor of mPTP and self-mtDNA cytosolic leakage effectively reduced NLRP3 inflammasome-mediated pyroptotic NP cell death and microenvironmental inflammation in vitro and degenerative progression in a rat disc needle puncture model. Collectively, these data highlight the critical roles of the cGAS-STING-NLRP3 axis and pyroptosis in the progression of IVD degeneration and provide promising therapeutic approaches for discogenic LBP.

Research and Application of Fiber Bragg Grating Sensor in Geological Disaster Automation Monitoring

Liu Yimin,Wang Jie,Ji Weifeng,Zhou Ce,Chen Wenjun 보안공학연구지원센터 2014 International Journal of Control and Automation Vol.7 No.10

In this paper, fiber grating technology is used for accurately measure stresses, temperature and displacement. The paper introduces the basic principles of FBG technology and the wavelength demodulation method of FBG sensors, and put fiber grating technology into practical engineering projects. The paper design a optical fiber grating real-time automation monitoring system to distributed measure stress, temperature and displacement in geological disaster body, to provide effective technical supports for geological disaster prevention and mitigation.

Fabrication of Cu2SnS3 Thin Films by Ethanol-Ammonium Solution Process by Doctor-Blade Technique

Yaguang Wang,Jianmin Li,Cong Xue,Yan Zhang,Guoshun Jiang,Weifeng Liu,Changfei Zhu 대한금속·재료학회 2017 ELECTRONIC MATERIALS LETTERS Vol.13 No.6

In the present study, a low-cost and simple method is applied to fabricate Cu2SnS3(CTS) thin films. Namely CTS thin films are prepared by a doctor-blade method with aslurry dissolving the Cu2O and SnS powders obtained from CBD reaction solution intoethanol-ammonium solvents. Series of characterization methods including XRD,Raman spectra, SEM and UV-Vis analyses are introduced to investigate the phasestructure, morphology and optical properties of CTS thin films. As a result, monoclinicCTS films have been obtained with the disappearance of binary phases CuS and SnS2while increasing the annealing temperature and time, high quality monoclinic CTS thinfilms consisting of compact and large grains have been successfully prepared by thisethanol-ammonium method. Moreover, the secondary phase Cu2Sn3S7 is also observedduring the annealing process. In addition, the post-annealed CTS film with a band-gapabout 0.89 eV shows excellent absorbance between 400 and 1200 nm, which is properfor the bottom layer in multi-junction thin film solar cells.

A Meta-Analysis of the Accuracy of Prostate Cancer Studies Which Use Magnetic Resonance Spectroscopy as a Diagnostic Tool

Peng Wang,You-min Guo,Min Liu,Yong-qian Qiang,Xiao-juan Guo,Yi-li Zhang,Xiao-Yi Duan,Qiu-Juan Zhang,Weifeng Liang 대한영상의학회 2008 Korean Journal of Radiology Vol.9 No.5

Objective: We aimed to do a meta-analysis of the existing literature to assess the accuracy of prostate cancer studies which use magnetic resonance spectroscopy (MRS) as a diagnostic tool. Materials and Methods: Prospectively, independent, blind studies were selected from the Cochrane library, Pubmed, and other network databases. The criteria for inclusion and exclusion in this study referenced the criteria of diagnostic research published by the Cochrane center. The statistical analysis was adopted by using Meta-Test version 6.0. Using the homogeneity test, a statistical effect model was chosen to calculate different pooled weighted values of sensitivity, specificity, and the corresponding 95% confidence intervals (95% CI). The summary receiver operating characteristic (SROC) curves method was used to assess the results. Results: We chose two cut-off values (0.75 and 0.86) as the diagnostic criteria for discriminating between benign and malignant. In the first diagnostic criterion, the pooled weighted sensitivity, specificity, and corresponding 95% CI (expressed as area under curve [AUC]) were 0.82 (0.73, 0.89), 0.68 (0.58, 0.76), and 83.4% (74.97, 91.83). In the second criterion, the pooled weighted sensitivity, specificity, and corresponding 95% CI were 0.64 (0.55, 0.72), 0.86 (0.79, 0.91) and 82.7% (68.73, 96.68). Conclusion: As a new method in the diagnostic of prostate cancer, MRS has a better applied value compared to other common modalities. Ultimately, large scale RCT randomized controlled trial studies are necessary to assess its clinical value. Objective: We aimed to do a meta-analysis of the existing literature to assess the accuracy of prostate cancer studies which use magnetic resonance spectroscopy (MRS) as a diagnostic tool. Materials and Methods: Prospectively, independent, blind studies were selected from the Cochrane library, Pubmed, and other network databases. The criteria for inclusion and exclusion in this study referenced the criteria of diagnostic research published by the Cochrane center. The statistical analysis was adopted by using Meta-Test version 6.0. Using the homogeneity test, a statistical effect model was chosen to calculate different pooled weighted values of sensitivity, specificity, and the corresponding 95% confidence intervals (95% CI). The summary receiver operating characteristic (SROC) curves method was used to assess the results. Results: We chose two cut-off values (0.75 and 0.86) as the diagnostic criteria for discriminating between benign and malignant. In the first diagnostic criterion, the pooled weighted sensitivity, specificity, and corresponding 95% CI (expressed as area under curve [AUC]) were 0.82 (0.73, 0.89), 0.68 (0.58, 0.76), and 83.4% (74.97, 91.83). In the second criterion, the pooled weighted sensitivity, specificity, and corresponding 95% CI were 0.64 (0.55, 0.72), 0.86 (0.79, 0.91) and 82.7% (68.73, 96.68). Conclusion: As a new method in the diagnostic of prostate cancer, MRS has a better applied value compared to other common modalities. Ultimately, large scale RCT randomized controlled trial studies are necessary to assess its clinical value.

Influence of the axial radius of rigid arc-shaped rollers in 3D surface rolling

Xintong Wang,Ming-Zhe Li,Yuwei Liu,Xiang Chang,Weifeng Yang 대한기계학회 2021 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.35 No.8

The research and development of flexible forming technology have a crucial role in the personalized production and manufacturing of three-dimensional (3D) surface sheet metal parts. Three-dimensional surface rolling with rigid arc-shaped rollers (TSRRAR), a new flexible forming technology, was investigated to effortlessly produce 3D surface parts. Numerical simulation and experimental analysis mainly include data at four values of the difference in axial radius of roller (-2, 2, 6 and 10 mm) to explore this technology’s forming ability. It was demonstrated that various shapes could be obtained only based on one group of rollers. The maximum resultant force decreased from 3.07 to 2.21 KN, and the required maximum compression rate from 4.22 to 2.48 % with the same longitudinal curvature radius (179 mm) to be obtained. Therefore, the forming difficulty can be reduced by selecting the difference in axial radius of roller.

Cauchy mutation boosted Harris hawk algorithm: optimal performance design and engineering applications

Shan Weifeng,He Xinxin,Liu Haijun,Heidari Ali Asghar,Wang Maofa,Cai Zhennao,Chen Huiling 한국CDE학회 2023 Journal of computational design and engineering Vol.10 No.2

Harris hawks optimization (HHO) has been accepted as one of the well-established swarm-based methods in the community of optimization and machine learning that primarily works based on multiple dynamic features and various exploratory and exploitative traits. Compared with other optimization algorithms, it has been observed that HHO can obtain high-quality solutions for continuous and constrained complex and real-world problems. While there is a wide variety of strategies in the HHO for dealing with diverse situations, there are chances for sluggish performance, where the convergence rate can gradually slow with time, and the HHO may stay stuck in the current relatively better place and may be unable to explore other better areas. To mitigate this concern, this paper combines the Cauchy mutation mechanism into the HHO algorithm named CMHHO. This idea can boost performance and provide a promising optimizer for solving complex optimization problems. The Cauchy mutation mechanism can speed up the convergence of the solution and help HHO explore more promising regions compared to its basic release. On 30 IEEE CEC2017 benchmark functions, the study compared the proposed CMHHO with various conventional and advanced metaheuristics to validate its performance and quality of solutions. It has been found through experiments that the overall optimization performance of CMHHO is far superior to all competitors. The CMHHO method is applied to four engineering challenges to investigate the capabilities of the proposed algorithm in solving real-world problems, and experimental results show that the suggested algorithm is more successful than existing algorithms.

Oriented-SLA and Energy-Efficient Virtual Machine Management Strategy of Cloud Data Centers

Lijun Xu,Weifeng Wang,Xiaoqing Zhang 보안공학연구지원센터 2016 International Journal of Grid and Distributed Comp Vol.9 No.1

Cloud computing has revolutionized the information and communication technology industry by enabling on-demand provisioning of elastic computing resources on a pay-as-you-go basis. However, due to the large-scale popularization and application, cloud data centers consume enormous amounts of electrical energy, which results in high operating costs and carbon dioxide emissions. In this paper, twenty-two algorithms are simulated for testing the trade-off between the applications performance and energy consumption during virtual machine management of cloud data centers in CloudSim simulation toolkit. The goal of these algorithms is to reduce energy consumption under ensuring the performace of cloud applications. A large number of simulation experimental results prove the performance of these twenty-two algorithms respectively.

Protective effect of Insect tea primary leaf (Malus sieboldii (Regal) Rehd.) extract on H2O2‑induced oxidative damage in human embryonic kidney 293T cells

Zhang Jing,Wang Hong,Yi Sha,Guo Zemei,Huang Yue,Li Weifeng,Zhao Xin,Liu Huazhi 한국응용생명화학회 2020 Applied Biological Chemistry (Appl Biol Chem) Vol.63 No.3

In this study, Insect tea primary leaf (Malus sieboldii (Regal) Rehd.) was used as the research object to investigate the protective effect of Insect tea primary extract (ITPLE) on hydrogen peroxide (H2O2)-induced oxidative damage in human embryonic kidney 293T cells (HEK 293T cells) and the mechanism of action of the main active components. The 3-(4,5-dimethyl-2-thiazolyl)- 2,5-diphenyl-2-H-tetrazolium bromide (MTT) assay was used to determine the toxicity of ITPLE to HEK 293T cells in vitro as well as its protective effect against (H2O2)-induced oxidative damage in HEK 293T cells. In addition, various assay kits were used to measure oxidation-related indicators in HEK 293T cells, and quantitative polymerase chain reaction (qPCR) analysis was used to determine the mRNA expression levels of oxidation-related genes in HEK 293T cells. High performance liquid chromatography (HPLC) analysis was used to characterize active components in ITPLE. The experimental results revealed that the ITPLE had no toxic effect on cells in the range of 0–200 μg/mL, and, in this range, exhibited a concentration-dependent protective effect against H2O2- induced oxidative damage in HEK 293T cells. It was also found that the ITPLE can reduce the malondialdehyde (MDA) level and increase the levels of superoxide dismutase (SOD), glutathione (GSH), glutathione peroxidase (GSH-Px), and catalase (CAT)in oxidative damage HEK 293T cells. The qPCR analysis results also showed that the ITPLE upregulated the mRNA expression levels of SOD, CAT , GSH and GSH-Px in HEK 293T cells damaged by H2O2- induced oxidative stress. The HPLC analysis identified 7 bioactive components in the ITPLE, including neochlorogenic acid, cryptochlorogenic acid, rutin, kaempferin, isochlorogenic acid B, isochlorogenic acid A and hesperidin. This study reveals that ITPLE is rich in active compounds and has good antioxidant effect in vitro, thus it has the potential to be developed into a traditional Chinese medicine and functional drinks.