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      • SCOPUS

        Influences of Financial Inclusion on Sustainable Development of India: Using Internet Subscribers as a Moderator

        Swapnil Singh THAKUR(Swapnil Singh THAKUR ),Rahul Singh GAUTAM(Rahul Singh GAUTAM ),Ajay Kumar YADAV(Ajay Kumar YADAV ),Hitesh PATOLE(Hitesh PATOLE ),Aashi RAWAL(Aashi RAWAL ),Shailesh RASTOGI(Shailes 한국유통과학회 2023 The Journal of Asian Finance, Economics and Busine Vol.10 No.2

        The goal of this study is to understand how financial inclusion (FI) as influenced by Internet subscribers in India, affects India’s Sustainable Development Goals (SDG). This study makes use of secondary data that was collected from 16 Indian states and one Union Territory between the fiscal years of 2018 and 2020. The goal of this study has been investigated using panel data regression analysis (PDR). And the study’s findings indicate that wages received through MNREGA accounts and post office operating accounts under the supervision of Internet subscribers have a significant negative impact on India’s SDGs, demonstrating how financial inclusion is harming the country’s efforts to achieve sustainable development. This study suggests that it is important to pay attention to rural areas’ access to the digital environment and their degree of digital literacy. These findings imply that improving the MGNREGA program and employees’ pay might help the government alleviate poverty in India. Financial inclusion also depends heavily on financial literacy. The government should improve its digital infrastructure in rural and urban areas so that people there may better understand and utilize it given that it promotes financial inclusion, digitalization, economic advancement, rural development, and poverty reduction.

      • KCI등재

        Transcriptome profiling and characterization of genes associated with tuberization under high temperature in aeroponics in potato cv. Kufri Anand

        Zinta Rasna,Tiwari Jagesh Kumar,Buckseth Tanuja,Goutam Umesh,Singh Rajesh Kumar,Kumar Vinod,Thakur Ajay Kumar 한국유전학회 2024 Genes & Genomics Vol.46 No.4

        Background High temperature stress is an important abiotic factor, which affects tuberization and ultimately causes heavy yield reduction in potato. Objectives Identification and characterization of genes associated with tuberization under high temperature stress is essential for future management through biotechnology. Methodology Two contrasting potato varieties Kufri Anand (profuse tuber-bearing) versus Kufri Frysona (very less/scanty tuber-bearing, control) were cultivated in aeroponics under high temperature stress, and transcriptomes were analyzed. Results Potato cv. Kufri Anand was found superior over control (Kufri Frysona) for tuber yield and its component traits along with root morphology under aeroponics. Transcriptomes of tuber and leaf tissues were analyzed. Statistically significant (p < 0.05) differentially expressed genes (DEGs) were categorised into up-regulated (> 2 log2 fold change, FC) and down-regulated (< -2 log2 FC) genes. DEGs were annotated by gene ontology and KEGG pathways. A few selected up-regulated genes of both tissues were identified, and phylogeny tree and motif analysis were analysed based on 36 peptide sequences representing 15 selected DEGs in this study. Further, gene expression markers were developed and validated by real time qPCR analysis for the identification of high temperature tolerant genotypes. Conclusion A few key genes associated in tuberization under high temperature conditions were heat shock proteins (e.g. 18.5 kDa class I heat shock protein), sugar metabolism (e.g. glucosyltransferase), transcription factor (e.g. WRKY), and phytohormones (e.g. auxin-induced beta-glucosidase). Our study provides an overview of key genes involved in tuberization under high temperature stress in potato cv. Kufri Anand under aeroponics. Background High temperature stress is an important abiotic factor, which affects tuberization and ultimately causes heavy yield reduction in potato. Objectives Identification and characterization of genes associated with tuberization under high temperature stress is essential for future management through biotechnology. Methodology Two contrasting potato varieties Kufri Anand (profuse tuber-bearing) versus Kufri Frysona (very less/scanty tuber-bearing, control) were cultivated in aeroponics under high temperature stress, and transcriptomes were analyzed. Results Potato cv. Kufri Anand was found superior over control (Kufri Frysona) for tuber yield and its component traits along with root morphology under aeroponics. Transcriptomes of tuber and leaf tissues were analyzed. Statistically significant (p < 0.05) differentially expressed genes (DEGs) were categorised into up-regulated (> 2 log2 fold change, FC) and down-regulated (< -2 log2 FC) genes. DEGs were annotated by gene ontology and KEGG pathways. A few selected up-regulated genes of both tissues were identified, and phylogeny tree and motif analysis were analysed based on 36 peptide sequences representing 15 selected DEGs in this study. Further, gene expression markers were developed and validated by real time qPCR analysis for the identification of high temperature tolerant genotypes. Conclusion A few key genes associated in tuberization under high temperature conditions were heat shock proteins (e.g. 18.5 kDa class I heat shock protein), sugar metabolism (e.g. glucosyltransferase), transcription factor (e.g. WRKY), and phytohormones (e.g. auxin-induced beta-glucosidase). Our study provides an overview of key genes involved in tuberization under high temperature stress in potato cv. Kufri Anand under aeroponics.

      • KCI등재

        Identification of New Source of Resistance to Powdery Mildew of Indian Mustard and Studying Its Inheritance

        Joghee Nanjundan,Channappa Manjunatha,Jalli Radhamani,Ajay Kumar Thakur,Rashmi Yadav,Arun Kumar,Mohan Lal Meena,Rishi Kumar Tyagi,Devender Kumar Yadava,Dhiraj Singh 한국식물병리학회 2020 Plant Pathology Journal Vol.36 No.2

        Powdery mildew of Indian mustard (Brassica juncea), caused by Erysiphe cruciferarum, is emerging as ma- jor problem in India. All the Indian mustard cultivars presently grown in India are highly susceptible to pow- dery mildew and so far no resistance source has been reported. In this study, with an aim to identify resistant source, 1,020 Indian mustard accessions were evaluated against E. cruciferarum PMN isolate, at Wellington, The Nilgiris, Tamil Nadu, India under natural hot spot conditions. The study identified one accession (RDV 29) with complete resistance against E. cruciferarum PMN isolate for the first time, which was consistent in five independent evaluations. Genetic analysis of F1, F2 and backcross populations obtained from the cross RSEJ 775 (highly susceptible) × RDV 29 (highly resistant) for two season revealed that the resistance is governed by two genes with semi-dominant and gene dosage effect. Further, a new disease rating system using six scales (0, 1, 2, 3, 4, and 5) has also been proposed in this study to score powdery mildew based on progress of fungal growth in different plant parts of the F2 population. The outcome of this study viz. newly identified powdery mildew-resistant Indian mustard accession (RDV 29), information on inheritance of resistance and the newly developed disease rating scale will provide the base for development of powdery mildew-resistant cultivars of Indian mustard.

      • KCI등재

        Comprehensive loss modeling in Cu2ZnSnS4 solar cells

        Atul Kumar,Ajay D. Thakur 한국물리학회 2019 Current Applied Physics Vol.19 No.10

        Thin film solar cells based on Cu2ZnSnS4 (CZTS) absorber material suffers from performance issues arising due to the presence of a non-optimal back contact barrier, low carrier lifetime, acceptor/donor point defects in bulk, interface defects at the absorber-buffer junction and grain boundaries within the absorber. We perform comprehensive simulations enumerating the impact of these performance limiting factors on CZTS solar cells. These simulations capture the experimentally observed anomalies in current-voltage (I–V) characteristics and the opencircuit voltage (VOC) pinning in CZTS solar cells. These cause-effect relationships as elaborated in the findings are expected to be of great interest to the experimentalists working in this field.

      • KCI등재

        Silver nitrate and silver-thiosulphate mitigates callus and leaf abscission during Shisham clonal micro-propagation

        Manoj Kumar Raturi,Ajay Thakur 한국식물생명공학회 2021 JOURNAL OF PLANT BIOTECHNOLOGY Vol.48 No.3

        Basal callus formation and leaf abscission is a problem in clonal micropropagation. We have described an in vitro clonal propagation protocol of Dalbergia sissoo Roxb (shisham) ‘FRI-14’ in which AgNO3 played important role not only in mitigating problem of leaf abscission and basal callus, but also improved shoot induction and multiplication. Best induction and shoot multiplication was obtained on MS media with 1.5 mg/l 6-BAP and 10 mg/l AgNO3 and half-strength MS media with 0.5 mg/l 6-BAP, 2 mg/l AgNO3 and 50 mg/l Adenine sulphate whereas best ex vitro rooting was obtained with 200 mg/l IBA in pulse treatment.

      • Development of chitosan-catechol conjugates as mucoadhesive polymer: assessment of acute oral toxicity in mice

        Loveleen Kaur,Ritu Raj,Ajay Kumar Thakur,Inderbir Singh 환경독성보건학회 2020 환경독성보건학회지 Vol.35 No.3

        Development of modified polymers is the focused area of research for developing stable, effective, sustainable and economical polymeric materials for developing different drug delivery systems. Modification of chitosan by catechol functionalization is useful for developing chitosan derivative with the improved mucoadhesive property. Present study was designed to perform single dose acute oral toxicity on chitosan-catechol conjugates in Swiss albino mice as per international guidelines. Oral administration of modified chitosan did not exhibit any significant change in body weight, behavioural pattern, haematology, food intake and clinical symptoms in the experimental animals. In the histopathological study, no pathological changes were observed in the vital organs of mice when administered perorally with 300 mg/kg and 2,000 mg/kg body-weight doses of chitosan-catechol polymeric conjugates. Overall, it was concluded from the acute oral toxicity study that the oral administration of chitosan-catechol conjugates in mice did not produce any toxicity. Hence, chitosan-catechol conjugates could be designated and recommended as safe polymeric material for developing different drug delivery systems.

      • KCI등재

        Brief Report : Effects of Intramuscular Electrical Stimulation Using Inversely Placed Electrodes on Myofascial Pain Syndrome in the Shoulder -A Case Series

        ( Sukumar Shanmugam ),( Lawrence Mathias ),( Ajay Thakur ),( Dhanesh Kumar ) 대한통증학회 2016 The Korean Journal of Pain Vol.29 No.2

        Myofascial pain syndrome (MPS) is one of the common musculoskeletal conditions of the shoulder which may develop sensory-motor and autonomic dysfunctions at the various level of the neuromuscular system. The pain and dysfunction caused by MPS were primarily treated with physical therapy and pharmacological agents in order to achieve painfree movements. However, in recent years intramuscular electrical stimulation (IMES) with conventional electrode placement was used by researchers to maximise therapeutic values. But, in this study an inverse electrode placement was used to deliver electrical impulses intramuscularly to achieve neuro-modulation at the various level of the nervous system. Nine patients with MPS were treated with intramuscular electrode stimulation using inversely placed electrodes for a period of three weeks. All nine subjects recovered from their shoulder pain and disability within the few weeks of intervention. So, this inverse electrode placement may be more appropriate for chronic pain management. (Korean J Pain 2016; 29: 136-40)

      • SCOPUSKCI등재

        Effects of Intramuscular Electrical Stimulation Using Inversely Placed Electrodes on Myofascial Pain Syndrome in the Shoulder - A Case Series

        Shanmugam, Sukumar,Mathias, Lawrence,Thakur, Ajay,Kumar, Dhanesh The Korean Pain Society 2016 The Korean Journal of Pain Vol.29 No.2

        Myofascial pain syndrome (MPS) is one of the common musculoskeletal conditions of the shoulder which may develop sensory-motor and autonomic dysfunctions at the various level of the neuromuscular system. The pain and dysfunction caused by MPS were primarily treated with physical therapy and pharmacological agents in order to achieve painfree movements. However, in recent years intramuscular electrical stimulation (IMES) with conventional electrode placement was used by researchers to maximise therapeutic values. But, in this study an inverse electrode placement was used to deliver electrical impulses intramuscularly to achieve neuro-modulation at the various level of the nervous system. Nine patients with MPS were treated with intramuscular electrode stimulation using inversely placed electrodes for a period of three weeks. All nine subjects recovered from their shoulder pain and disability within the few weeks of intervention. So, this inverse electrode placement may be more appropriate for chronic pain management.

      • KCI등재

        Analysis of clinical and radiological outcomes of long tibial stemmed total knee arthroplasty in knee osteoarthritis complicated by tibial stress fracture

        ( Neelam V. Ramana Reddy ),( Mukesh Kumar Saini ),( Pera Jayavardhan Reddy ),( Ajay Singh Thakur ),( Challa Dinesh Reddy ) 대한슬관절학회 2022 대한슬관절학회지 Vol.34 No.-

        Objective: Knee arthritis associated with tibial stress fractures represents an uncommon and difficult clinical scenario to treat. The use of long, fluted tibial extension rods has been vital in the management of such cases owing to immediate fracture stability and single-stage surgery without the need to open the fracture site. This study investigates clinical and radiological outcomes following total knee arthroplasty using a tibial extension stem in cases of knee osteoarthritis with tibial stress fracture. Methods: From February 2015 to December 2020, 17 patients who had total knee arthroplasty implanted with a long stemmed tibial component were included in the study. Patient data were analyzed for knee range of motion, deformities, Knee Society score, knee function score, and time to fracture union in the pre- and postoperative periods. Results: The mean follow-up duration was 22.7 ± 11.68 months (range 12-60 months), and mean time to fracture healing was 10.23 ± 2.81 weeks (range 8-20 weeks). The preoperative mean fixed flexion deformity improved from 8.53 ± 3.43° to a mean of 0.29°, and knee flexion improved from 79.4 ± 13.90° to 125.29 ± 8.74° on postoperative assessment. The Knee Society score improved from a mean preoperative score of 18.94 ± 5.55 (range 8-28) to 89.41 ± 7.5 (range 74-102, p value < 0.001). Similarly, the knee function score improved significantly from a mean preoperative score of 15.5 ± 4.48 (range 8-26) to a mean of 85 ± 6.09 (range 72-94, p value < 0.001). Conclusion: Total knee arthroplasty using long tibial extenders has been an effective and safe surgical option for patients with advanced osteoarthritis with tibial stress fractures.

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