Stilbenes and Oligostilbenes from Leaf and Stem of Vitis amurensis and Their Cytotoxic Activity

Do Thi Ha,Quan Cheng Chen,Tran Manh Hung,Tran Minh Ngoc,Phuong Thien Thuong,김홍진,성연희,민병선,배기환,윤의중 대한약학회 2009 Archives of Pharmacal Research Vol.32 No.2

Chromatographic separation of the EtOAc fraction from the leaf and stem of Vitis amurensis led to the isolation of six oligostilbenoids (i.e., r-2-viniferin (1), trans-amurensin B (2), trans-ε -viniferin (3), gnetinH (4), amurensin G (5), (+)-ampelopsin A (8)) and four stilbenoids (i.e., trans-resveratrol (6), (+)- ampelopsin F (7), piceatannol (9), and trans-piceid (10)). The structures have been identified on the basis of spectroscopic evidence and physicochemical properties. The isolates were investigated for cytotoxic activity against three cancer cell lines in vitro using the MTT assay method. Amurensin G (5) and trans-resveratrol (6) showed significant cytotoxic activity against L1210, K562 and HTC116 cancer cell lines with IC50 values ranging from 15.7 ± 2.1 to 30.9 ± 1.8 μM. (+)-Ampelopsin A (8) and trans-piceid (10) exhibited considerable cytotoxic activity against L1210 (IC50 values of 30.6 ± 4.1 and 28.7 ± 2.81μM, respectively) and K562 (IC50 values of 38.6 ± 0.82 and 24.6 ± 0.76 μM, respectively). Gnetin H (4)showed only weak cytotoxic activity against L1210 with an IC50 value of 40.1 ± 4.23 μM. On the other hand, r-2-viniverin (1), trans-amurensin B (2), trans-ε -viniferin (3), (+)-ampelopsin F (7), and piceatannol(9) exhibited no activity on three cancer cell lines.

Identification of Soluble Epoxide Hydrolase Inhibitors from the Seeds of Passiflora edulis Cultivated in Vietnam

To Dao Cuong,Hoang Thi Ngoc Anh,Tran Thu Huong,Pham Ngoc Khanh,Vu Thi Ha,Tran Manh Hung,김영호,Nguyen Manh Cuong 한국생약학회 2019 Natural Product Sciences Vol.25 No.4

Soluble epoxide hydrolases (sEH) are enzymes present in all living organisms, metabolize epoxy fatty acids to 1,2-diols. sEH in the metabolism of polyunsaturated fatty acids plays a key role in inflammation. In addition, the endogenous lipid mediators in cardiovascular disease are also broken down to diols by the action of sEH that enhanced cardiovascular protection. In this study, sEH inhibitory guided fractionation led to the isolation of five phenolic compounds trans-resveratrol (1), trans-piceatannol (2), sulfuretin (3), (+)-balanophonin (4), and cassigarol E (5) from the ethanol extract of the seeds of Passiflora edulis Sims cultivated in Vietnam. The chemical structures of isolated compounds were determined by the interpretation of NMR spectral data, mass spectra, and comparison with data from the literature. The soluble epoxide hydrolase (sEH) inhibitory activity of isolated compounds was evaluated. Among them, trans-piceatannol (2) showed the most potent inhibitory activity on sEH with an IC50 value of 3.4 mM. This study marks the first time that sulfuretin (3) was isolated from Passiflora edulis as well as (+)-balanophonin (4), and cassigarol E (5) were isolated from Passiflora genus.

Macroeconomic Conditions and Capital Structure Adjustment Speed - The Evidence in Vietnam

Tran,Thi Muoi,Nguyen,Thi Uyen Uyen 한국유통과학회 2019 KODISA ICBE (International Conference on Business Vol.2019 No.-

The relationship between capital structure and corporate value is a topic that has been and can continue to be studied by scientists around the world and Vietnam because of its helpful. The empirical evidences show that the capital structure has an impact on the value of the enterprise; therefore, businesses are always looking for an optimal capital structure to finance. In addition, many studies have shown that there is always an optimal capital structure in enterprises where the value of the enterprise is the highest, which has led to the tendency of enterprises to adjust the capital structure to achieve an optimal capital structure, that makes the capital structure of the enterprise is not static, it is always dynamic. Moreover, the study of the impact of factors on the capital structure of enterprises is also interested by many researchers in the world and Vietnam such as characteristic and macroeconomic factors; especially in the world there have been many studies on the impact of macroeconomic conditions on the speed of capital structure adjustment of enterprises, however, this subject in Vietnam is not mentioned. With this gap, the author determines to study the impact of macroeconomic conditions on the capital structure adjustment speed of Vietnam enterprises in the period 2006 -2015.

A Review of Accounting Research Trends in the World

Tran,Thi Phuong Thanh 한국유통과학회 2019 KODISA ICBE (International Conference on Business Vol.2019 No.-

Trends in international accounting harmonization are extensive, so that demand on accounting research to meet international standards is more necessary and instant. The purpose of this paper is to conduct a review of accounting papers and find out the main characteristics of current accounting research trends in the world. I investigate trends by examining papers published in six top accouting journals (JCR 2015) from 2015 to 2016. I used citations made by accounting papers as a proxy for ranking and examine trends in topics and methodologies of these papers. This paper’s results suggest that financial accounting topics and archival methodologies are becoming more significantly over time during the research period. Moreover, the results also show that the movement in accounting research trends from a normative perspective to a positive perspective, especially an experimental research. From these results, I discuss the major characteristics of future accounting research trends and give some implications about accounting research to Vietnamese researchers.

QUÁ TRÌNH THỐNG NHẤT LUẬT HÔN NHÂN VÀ GIA ĐÌNH SAU KHI ĐẤT NƯỚC THỐNG NHẤT TẠI VIỆT NAM

TRAN THI HUONG 한국가족법학회 2015 한국가족법학회 학술대회 논문집 Vol.2015 No.2

The Relationship Between Business Resources, Outside Cooperation, Dynamic Capability, and Performance of Startup Enterprises

Dong Van VU1,Tai Van PHAM2,Ghi Nha TRAN3,Anh Phuong Thi NGUYEN4,Cong Van NGUYEN5 한국유통과학회 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.6

This study seeks to examine the relationship between business resources (through VRIN: Valuable - valuable, Rare - scarce; Inimitable - difficult to adapt, Irreplaceable - hard to replace), dynamic capability, external cooperation, and efficiency of startups operating in the seafood export sector. Research data was collected randomly and conveniently from 250 enterprises in Ba Ria-Vung Tau province, Vietnam, from October 2020 to December 2020. After excluding those ineligible, the remaining 204 enterprises meet the research conditions. With the support of SPSS-AMOS 22 dedicated software, using the 5-step Likert scale and Structural Equation Modeling (SEM), the study conducted analysis steps such as verifying convergence, discriminant value, unidirectional and scale reliability when giving the components correlated freely in the critical model by Confirmatory Factor Analysis (CFA) analysis. Results of the study have shown that the enterprise resource factor - VRIN has a positive impact on dynamic capability, and outside cooperation. However, in contrast to previous studies, we found that the relationship between enterprise resources - VRIN and performance as well as the relationship between dynamics capacity and performance is not clear. This shows that seafood exporters need to promote, exploit and effectively use this precious resource to improve business efficiency.

Effects of Job Satisfaction on Organizational Commitment and Turnover Intention Among Vietnamese Employees in Foreign Direct Investment Enterprises

Thi Phuong Diu TRAN(Thi Phuong Diu TRAN ),Thi Van Khanh NGUYEN(Thi Van Khanh NGUYEN ),Thanh Quang DO3(Thanh Quang DO3 ),Cong Nghiep NGUYEN(Cong Nghiep NGUYEN ),Thu Thuy LUONG(Thu Thuy LUONG ) 한국유통과학회 2022 유통과학연구 Vol.20 No.10

Purpose: This article focuses on exploring the associations between job satisfaction, organizational commitment, and turnover intention. Specifically, this study estimates the impacts of Vietnamese employees’ job satisfaction on their organizational commitment and turnover intention in FDI enterprises. Research design, data and methodology: The measures are adapted from previous studies to develop a questionnaire with a seven-point Likert scale. The dataset is directly collected from 227 respondents who are employees at FDI enterprises situated in the North of Vietnam. The dataset is analyzed by quantitative approaches using SPSS 24.0 and AMOS 24.0. Results: The results show that while turnover intention is positively correlated with monthly income, it is negatively correlated with job satisfaction and organizational commitment. Also, organizational commitment is positively associated with job satisfaction among employees at FDI enterprises in Vietnam. Conclusions: The findings of this study will serve as useful references for administrators of FDI enterprises and policymakers to promote employees’ job satisfaction and retain skilled employees.

Ngo Thi Nham`s Social Responsibility Ideas

진채옥 ( Tran Thi Thuy Ngoc ) 충남대학교 유학연구소 2015 儒學硏究 Vol.32 No.-

응오 티념(吳時任)은 시대성을 지니며 많은 분야에서 다양한 사상을 제시한 인물이다. 그는 큰 변동의 시대를 겪었으며, 세간에서 그에 대한 다양한 평가가 있었음에도 불구하고 18세기를 언급할 때는 언제나 응오 티 념이 빠질 수 없다. 그는 레-찐(黎-鄭)왕조에서 중요한 역할을 담당하며 이후 새롭게 일어선 떠이 썬(西山王朝, 레-찐 왕조를 무너뜨렸다)에서 중요한 관리가 된다. 그래서 그의 사상 속에는 그의 이런 복잡한 정치적 인생이 반영이 되어 있다. 18세기 베트남의 유명한 사상가인 응오 티 념은 국가의 여러 분야에 참여한 유학자였고 관직에서 물러난 후에는 유명한 선사(禪師)가 되었다. 이런 이유로 변화가 심한 특수한 상황 속에서 그의 사회적인 책임에 대한 생각은 과연 일관된 의미를 가진 것인가? 아니면 신하로서의 이익을 위해 역사적 흐름을 따르는 자의적(恣意的)인 것인 가? 이 글에서는 응오 티 념의 생각에서 서로 모순되고 충돌되는 양상과 함께 이 속에서 일관성과 변증적 원칙들을 살펴 사회적 책임에 대한 사상의 개념을 분석할 것이다. 또, 사회적 책임에 대한 사상은 본래 서양 경제학의 개념이지만 동양철학의 학설 중에 유교에서도 일찍부터 주목하며 관심을 가졌다는 것을 살펴볼 것이다. 사회적 변화의 환경 속에서 가장 뛰어난 사회적 책임을 실현하기 위한 철학을 선택하는 것은 시대의 움직임과 사상가들의 도전이다. 응오 티 념은 자신의 어려운 삶과 더불어 인민에 대한 사회적 책임의 정신으로서 시대의 난해한 물음에 대답을 하게 되었다. Ngo Thi Nham (1746 - 1803) was an epochal character whose thoughts are considered multi-faceted, multi-dimensional. He participated in the large fluctuations of the times; whether people liked him or not, judging him affirmatively or negatively, Ngo Thi Nham was always mentioned when issues related to the eighteenth century were under discussion. He made an important role to the Le-Trinh dynasty and after that, became a senior for Tay Son reign (which destroyed the Le-Trinh). That complicated political life was also reflected in his ideas. As one of the most known thinkers in Vietnam in the 18thcentury, he was a Confucian whom engaged in every change of the nation, and also a retreat Zen monk in the end of his life. Thus, does his social responsibility thought in such variable character have a consistent meaning, or arbitrary chased the history trend for serving personal benefits? This paper will explore the concept of Ngo Thi Nham``s social responsibility thoughts to point out the dialectical and consistent principles in them, though their appearances can be thought contradictory and conflicting to each other. This article also shows that, though social responsibility is an economics concept from the West, but it was always been early attentive from the perspective of Eastern philosophy, especially Confucianism . This concept was increasingly more attentionally in the context of social unrest. By this time, choose which philosophy to be the best performing social responsibility was a challenge to the thinkers and practicers of the era. Ngo Thi Nham had his answers for this conundrum by his social responsibility commitment through his life.

Isolation and Cytotoxic Potency of Endophytic Fungi Associated with Dysosma difformis, a Study for the Novel Resources of Podophyllotoxin

Hoa Thi Tran,Giang Thu Nguyen,Hong Ha Thi Nguyen,Huyen Thi Tran,Quang Hong Tran,Quang Ho Tran,Ngoc Thi Ninh,Phat Tien Do,Ha Hoang Chu,Ngoc Bich Pham 한국균학회 2022 Mycobiology Vol.50 No.5

Endophytic fungi are promising sources for the production of podophyllotoxin-an important anticancer compound, replacing depleted medical plants. In this study, the endophytes asso- ciated with Dysosma difformis-an ethnomedicinal plant species were isolated to explore novel sources of podophyllotoxin. Fifty-three endophytic fungi were isolated and identified by morphological observation and ITS-based rDNA sequencing, assigning them to 27 genera in 3 divisions. Fusarium was found the most prevalent genus with a colonization frequency of 11.11%, followed by Trametes (9.26%) and Penicillium (7.41%). Phylogenetic trees were constructed for the endophytic fungi community in two collection sites, Ha Giang and Lai Chau, revealing the adaptation of the species to the specific tissues and habitats. Cytotoxic activity of endophytic fungal extracts was investigated on cancer cell lines such as SK-LU-1, HL-60, and HepG2, demonstrating strong anti-cancer activity of six isolates belonging to Penicillium, Trametes, Purpureocillium, Aspergillus, and Ganoderma with IC50 value of lower than 10 mg/mL. The presence of podophyllotoxin was indicated in Penicillium, Trametes, Aspergillus and for the first time in Purpureocillium and Ganoderma via high-performance liquid chromatography, which implied them as a potential source of this anti- cancer compound.

Boosted micropollutants removal over NiFe₃O₄/Hydroxyapatite catalyst via persulfate activation

Thi Nhung Tran(Tran Thi Nhung),Jungwan Kang(강정완),Junho Kim(김준호),Seoktae Kang(강석태) 대한환경공학회 2022 대한환경공학회 학술발표논문집 Vol.2022 No.11