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G. Suresh,M. R. Ramesh,M. S. Srinath 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.8
This paper reports on a study of the high-temperature tribological performance of self-lubricating nickel-based compositeclad. A porous and crack free clad containing matrix, reinforcement, and lubricant phase is developed on titanium 31 alloyusing microwave irradiation. The microstructure of both NiCrSiB/WC and NiCrSiB/WC/Ag/BaF2 clad revealed very goodmetallurgical bonding with the substrate. The average microhardness of NiCrSiB/WC and NiCrSiB/WC/Ag/BaF2 clad is710.58 HV and 650.25 HV respectively, is comparatively higher than the titanium 31 substrate (320 HV). The addition of Agand BaF2solid lubricants in the clad endowing clad to operate at a broad temperature range. Compared with the NiCrSiB/WCclad, solid lubricant encapsulate clad has shown very low friction coefficient and wear rates. The sliding wear characteristicsof the clad were investigated by varying load and temperatures. The results revealed that oxide phases (NiO and Cr3O)andlubricant phases (Ag and BaWO4)formed at low and high temperatures are adequate to reduce delamination and material loss.
Medical student’s perception to different types of set induction in anatomy lectures
Suresh Narayanan,Suresh Narayanan,Nachiket Shankar,Vimala Ananthy 대한해부학회 2019 Anatomy & Cell Biology Vol.52 No.3
Set induction refers to the process of using a thought-provoking statement, interesting fact, or an audio-visual stimulus at the beginning of lecture to gain student’s attention and give an overview about the lecture topic. In the present study, students were introduced to three types of set induction namely narratives, food-based analogies and humor-based images or activities at the beginning of anatomy lecture and their response to it is collected and analyzed. The objective of the study is to estimate the difference in a questionnaire-based perception score between the three different types of set induction; estimate sex differences in the questionnaire-based perception score. Students rated the validated, 7-item perception questionnaire using a 5-point Likert scale. Students felt that food-based analogies and humor-based images were more interesting, motivated them to participate in lecture-discussion than the narrative set induction. The familiarity of set induction varied between all the three different types of set induction. There was no significant difference in the perception of different types of set induction between male and female undergraduate students. Based on the student’s feedback, it could also serve as a memory aid and ease the students learning experience. Majority of students responded positively to the use of set induction and recommended for its use in future classes.
The Importance of Ubiquitination and Deubiquitination in Cellular Reprogramming
Suresh, Bharathi,Lee, Junwon,Kim, Kye-Seong,Ramakrishna, Suresh Hindawi Publishing Corporation 2016 Stem cells international Vol.2016 No.-
<P>Ubiquitination of core stem cell transcription factors can directly affect stem cell maintenance and differentiation. Ubiquitination and deubiquitination must occur in a timely and well-coordinated manner to regulate the protein turnover of several stemness related proteins, resulting in optimal embryonic stem cell maintenance and differentiation. There are two switches: an E3 ubiquitin ligase enzyme that tags ubiquitin molecules to the target proteins for proteolysis and a second enzyme, the deubiquitinating enzyme (DUBs), that performs the opposite action, thereby preventing proteolysis. In order to maintain stemness and to allow for efficient differentiation, both ubiquitination and deubiquitination molecular switches must operate properly in a balanced manner. In this review, we have summarized the importance of the ubiquitination of core stem cell transcription factors, such as Oct3/4, c-Myc, Sox2, Klf4, Nanog, and LIN28, during cellular reprogramming. Furthermore, we emphasize the role of DUBs in regulating core stem cell transcriptional factors and their function in stem cell maintenance and differentiation. We also discuss the possibility of using DUBs, along with core transcription factors, to efficiently generate induced pluripotent stem cells. Our review provides a relatively new understanding regarding the importance of ubiquitination/deubiquitination of stem cell transcription factors for efficient cellular reprogramming.</P>
T. Suresh,P. Suresh,M. Prabu 한양대학교 청정에너지연구소 2024 Journal of Ceramic Processing Research Vol.25 No.2
In several research studies, many experiments have been conducted on non-traditional Electric Discharge Machining (EDM)and also investigated how different EDM process parameters influence the surface quality and productivity. EDM is a materialremoval process in which desired shape can be obtained by generation of spark. EDM process parameters play the vital role toimprove the surface finish and productivity simultaneously. This paper presents the effects of EDM machining parameter suchas Discharge ON Time, Discharge OFF Time, and Wire Feed, and their interactions on the Material Removal Rate (MRR) andSurface Roughness (SR) during the machining of magnesium matrix composites (MgZE41A) reinforced with Ag and LiAlO2. The hybrid composite of 97Mg+1.5Ag+1.5 LiAlO2 combination is selected for manufacture using powder metallurgy techniqueas it has a high wear resistance. Analysis of Variance (ANOVA) is adopted to study the influencing process parameters for eachresponse. Desirability function analysis (DFA) tool is adopted to find the optimal EDM process parameters which would reducethe surface roughness and improve the material removal rate simultaneously. From the analysis results it has been found thatdesirability ‘D’ of 0.55 gives the better results.
Suresh Alapati(수레수알라파티),Sangmo Kang(강상모),Yong Kweon Suh(서용권) 한국전산유체공학회 2009 한국전산유체공학회 학술대회논문집 Vol.2009 No.11
Translocation of biopolymers such as DNA and RNA through a nano-pore is an important process in biotechnology applications. The translocation process of a biopolymer through an artificial nano-pore in the presence of a fluid solvent is simulated. The polymer motion is simulated by Langevin molecular dynamics (MD) techniques while the solvent dynamics are taken into account by lattice-Boltzmann method (LBM). The hydrodynamic interactions are considered explicitly by coupling the polymer and solvent through the frictional and the random forces. From simulation results we found that the hydrodynamic interactions between polymer and solvent speed-up the translocation process. The translocation time τ<SUB>T</SUB> scales with the chain length N as τ<SUB>T</SUB><SUP>∝</SUP> N<SUP>α</SUP>. The value oj scaling exponents(α) obtained from our simulations are 1.29 ± 0.03 and 1.41 ± 0.03, with and without hydrodynamic interactions, respectively. Our simulation results are in good agreement with the experimentally observed value of α, which is equal to 1.27 ± 0.03, particularly when hydrodynamic interaction effects are taken into account.
Effect of Defect Location on the Swimming Speed of a Microscopic Artificial Swimmer
Suresh Alapati,Woo Seong Che,Yong Kweon Suh 한국전산유체공학회 2014 한국전산유체공학회 학술대회논문집 Vol.2014 No.10
The main objective of this work is to know the effect of defect location on the swimming speed of a microscopic artificial swimmer. The swimmer consists of an artificial filament composed of super-paramagnetic beads connected by elastic linkers and is modeled with a worm-like-chain configuration. The Rotne-Prager approximation is used to evaluate the hydrodynamic interactions between the filament and the fluid. To validate our numerical code, at first, we simulated the swimming motion of the filament without defect (without defect means the bending stiffness of the filament is uniform along its length). Next, we simulated the swimming motion of defective filament by setting the bending stiffness value at a particular bead location is equal to zero. We observed that when the defect location is on the load side of the filament, the swimming velocity is less than that of the filament without defect and vice versa. We also observed that at certain sperm numbers the swimming direction is reversed when the defect location is on the load side of the filament.
Magnetic ground state of the multiferroic hexagonal LuFeO3
Suresh, Pittala,Vijaya Laxmi, K.,Bera, A. K.,Yusuf, S. M.,Chittari, Bheema Lingam,Jung, Jeil,Anil Kumar, P. S. American Physical Society 2018 Physical Review B Vol.97 No.18
<P>The structural, electric, and magnetic properties of bulk hexagonal LuFeO3 are investigated. Single phase hexagonal LuFeO3 has been successfully stabilized in the bulk form without any doping by sol-gel method. The hexagonal crystal structure with P6(3)cm space group has been confirmed by x-ray-diffraction, neutron-diffraction, and Raman spectroscopy study at room temperature. Neutron diffraction confirms the hexagonal phase of LuFeO3 persists down to 6 K. Further, the x-ray photoelectron spectroscopy established the 3+ oxidation state of Fe ions. The temperature-dependent magnetic dc susceptibility, specific heat, and neutron-diffraction studies confirm an antiferromagnetic ordering below the Neel temperature (T-N) similar to 130 K. Analysis of magnetic neutron-diffraction patterns reveals an in-plane (ab-plane) 120 degrees antiferromagnetic structure, characterized by a propagation vector k = (0 0 0) with an ordered moment of 2.84 mu(B)/Fe3+ at 6 K. The 120 degrees antifferomagnetic ordering is further confirmed by spin-orbit coupling density functional theory calculations. The on-site coulomb interaction (U) and Hund's parameter (J(H)) on Fe atoms reproduced the neutron-diffraction Gamma(1) spin pattern among the Fe atoms. P-E loop measurements at room temperature confirm an intrinsic ferroelectricity of the sample with remnant polarization P-r similar to 0.18 mu(C) cm(2). A clear anomaly in the dielectric data is observed at similar to T-N revealing the presence of magnetoelectric coupling. A change in the lattice constants at T-N has also been found, indicating the presence of a strong magnetoelastic coupling. Thus a coupling between lattice, electric, and magnetic degrees of freedom is established in bulk hexagonal LuFeO3.</P>