English as the Medium of Instruction in Korean Engineering Education

Soyeon Kang,Hyeson Park 한국응용언어학회 2005 응용 언어학 Vol.21 No.1

인체 대장암 세포주 SW480에서 docosahexaenoic acid에 의한 침윤억제 기전

Soyeon Shin(신소연),Yong-Jo Kim(김용조),Kyoung-Sub Song(송경섭),Kaipeng Jing,Nayeong Kim(김나영),Soyeon Jeong(정소연),Ji-Hoon Park(박지훈),Kang-Sik Seo(서강식),Jun-Young Heo(허준영),Hyun-Joo Kwon(권현주),Jong-Il Park(박종일),Seung 한국생명과학회 2010 생명과학회지 Vol.20 No.4

대장암은 미국 등 서양 국가뿐만 아니라 국내에서도 2번째로 많이 발병이 되는 암으로 알려져 있다. 역학조사에 의하면 ω3-PUFAs를 많이 섭취한 인종에서 대장암 발생빈도가 감소하고 최근 ω3-PUFAs는 수종의 암에 대해 항암작용을 나타낸다고 한다. 이에 본 연구에서는 대장암에서 DHA 등 ω3-PUFA의 항침윤 기전을 규명하여 다음과 같은 결과를 얻었다. DHA 및 EPA는 대장암 세포주 SW480의 증식을 농도 의존적으로 억제하였으나 AA는 거의 영향이 없었으며 TUNEL assay로 apoptotic cell death가 확인 되었다. DHA는 β-catenin 단백 및 TCF/LEF luciferase 활성을 농도 의존적으로 억제 하였다. SW480 세포의 침윤능은 DHA의 농도에 의존적으로 억제되었다. DHA처리 후 MMP-9 및 MMP-2 mRNA양이 감소되었을 뿐만 아니라 그 promoter의 reporter 활성도 억제되었다. NF-kB 및 p-IkB 단백짙양도 DHA의 처리농도에 의존적으로 감소하였으며 NF-kB promoter의 활성도 억제되었다. 이상의 결과로 ω3-PUFA는 대장암에서 NF-kB 신호전달 차단에 의한 MMP-2 및 MMP-9 발현을 억제하여 침윤을 억제하여 항암작용을 나타낼 수 있음을 시사하며, 따라서 ω3-PUFA는 대장암의 예방 및 치료에 유용하게 사용될 수 있으리라 생각된다. Colon cancer is one of the most common malignancies in the western world and the second leading cause of cancer death in Korea. Epidemiology studies have shown a reduced incidence of colon cancer among populations consuming a large quantity of ω3-polyunsaturated fatty acids (ω3-PUFA) of marine origin. Recently, it has been found that ω3-PUFA has an antineoplastic effect in several cancers. This study was designed to investigate the mechanism of the anti-invasive effect of ω3-PUFA in colon cancer. ω3-PUFA, docosahexaenoic acids (DHA) and eicosapentaenoic acid (EPA) treatment resulted in a dose-dependent inhibition of cell growth in SW480 human colon cancer cells. In contrast, arachidonic acid (AA), a ω6-PUFA, exhibited no significant effect. This action likely involves apoptosis, given that DHA treatment increased apoptotic cells in TUNEL assay. Moreover, invasiveness of SW480 cells was inhibited following treatment of DHA in a dose-dependent manner; in contrast, AA had no effect. The levels of MMP-9 and MMP-2 mRNA decreased after DHA pretreatment. MMP-9 and MMP-2 promoter activities were also inhibited by DHA treatment. The levels of NF-kB and p-IkB protein were down-regulated by DHA pretreatment in a dose dependent manner. In addition, DHA inhibited NF-kB promoter reporter activities. These findings suggest that ω3-PUFA may inhibit cancer cell invasion by inhibition of MMPs via reduction of NF-kB in colon cancer. In conclusion, ω3-PUFA could be used for chemoprevention and treatment of human colon cancer.

Oncologic outcomes of preoperative stent insertion first versus immediate surgery for obstructing left-sided colorectal cancer

Kang, Sung Il,Oh, Heung-Kwon,Yoo, Jae Suk,Ahn, Soyeon,Kim, Min Hyun,Kim, Myung Jo,Son, Il Tae,Kim, Duck-Woo,Kang, Sung-Bum,Park, Young Soo,Yoon, Chang Jin,Shin, Rumi,Heo, Seung Chul,Lee, In Taek,Youk, Elsevier 2018 Surgical oncology Vol.27 No.2

<P><B>Abstract</B></P> <P><B>Background</B></P> <P>Colonic self-expanding metallic stenting (SEMS) is widely used for the treatment of malignant colonic obstruction as a bridge to elective surgery. However, the effects of colonic stenting on long-term oncologic outcomes are debatable. This study aimed to compare the long-term oncologic outcomes of preoperative SEMS insertion with those of immediate surgery in patients with obstructing left-sided colorectal cancer.</P> <P><B>Methods</B></P> <P>A cohort of consecutive patients who underwent radical surgery for obstructing left-sided colorectal cancer between 2004 and 2011 in five tertiary referral hospitals were analyzed. Long-term survivals were analyzed and adjusted using the inverse probability of treatment weighting method, based on propensity scores, to reduce selection bias.</P> <P><B>Results</B></P> <P>One hundred and nine patients underwent immediate surgery, and 226 underwent stent insertion before surgery. Disease-free survival did not differ significantly in both the unadjusted population (hazard ratio [HR] 1.063, 95% confidence interval [CI] 0.730–1.548; Log-rank, p = 0.746) and the adjusted population (HR 0.122, 95% CI 0.920–1.987; Log-rank, p = 0.122). Overall survival also did not differ significantly in both the unadjusted population (HR 0.871, 95% CI 0.568–1.334; Log-rank, p = 0.526) and the adjusted population (HR 1.023, 95% CI 0.665–1.572; Log-rank, p = 0.916). Defunctioning stoma formation was less in the SEMS insertion group than immediate surgery group (adjusted, 14.6% vs. 41.3%, p < 0.001).</P> <P><B>Conclusion</B></P> <P>The ‘bridge to surgery’ strategy using metallic stents was oncologically comparable to immediate surgery in patients with malignant left-sided colorectal obstruction.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Disease-free survival rate was comparable, SEMS insertion vs. immediate surgery. </LI> <LI> Overall survival rate was comparable between the two groups. </LI> <LI> Defunctioning stoma formation was less in the SEMS insertion group. </LI> <LI> The ‘bridge to surgery’ strategy using stent insertion was oncologically acceptable. </LI> </UL> </P>

The Role of Syntactic and Semantic Information in the Frequency Distribution of Relative Clauses in Korean : A Corpus-based Analysis

Soyeon Kang 고려대학교 언어정보연구소 2014 언어정보 Vol.19 No.-

The study investigated the constructional frequency of Korean relative clauses, focusing on the use of syntactic and semantic information in their production. The study investigated the constructional frequency of Korean relative clauses, focusing on the use of syntactic and semantic information in their production. A corpus study was conducted by automatically extracting all kinds of Korean head-external relative clauses through Perl programming from the Sejong Korean Parsed Written Corpus. The distributional frequency of the Korean relative clauses was analyzed in terms of syntactic information (grammatical functions of head NPs) and semantic information (animacy of heads and NPs within RCs). The results show that (a) Korean relative clauses are produced in order of subject > direct object > indirect object / oblique > genitive; (b) there is a correlation of subject relative clauses with animate heads and object relative clauses with inanimate heads; (c) the effect of syntactic information is more powerful when heads and NPs within RCs do not differ in animacy, whereas the effect of semantic information is more powerful when the two NPs differ in animacy; and (d) in Korean, in a difference from many other languages, the object relative clause is used frequently with inanimate heads and inanimate NPs within RCs. To sum up, both syntactic and semantic information were found to be important factors in the frequency distribution of Korean relative clauses.

Reproductive Life span and Severe Hypoglycemia Risk in Postmenopausal Women with Type 2 Diabetes

( Soyeon Kang ),( Jiyeon Hong ),( Ara Lee ),( Dongjin Kwon ),( Kyungdo Han ),( Seung-hyun Ko ) 대한산부인과학회 2021 대한산부인과학회 학술대회 Vol.107 No.-

Development 2.0

Christina Soyeon Kang,Bhavya Lal 과학기술정책연구원 2010 STI Policy Review Vol.1 No.3

가상현실을 통한 디지털 공간감 재현

강소연(Soyeon Kang) 한국HCI학회 2020 한국HCI학회 학술대회 Vol.2020 No.2

태양광 모듈의 반사방지 코팅 성능 평가

강소연(Kang Soyeon),김주희(Kim Juhee),김정식(Kim Jungsik),오원욱(Oh Wonwook),천성일(Chan Sungll) 한국태양에너지학회 2016 한국태양에너지학회 논문집 Vol.36 No.5

In this paper, we evaluated the effect of a silica-based Anti-Reflection(AR) coating for PV modules. The coating technique can be easily applied to large-scale PV modules at room temperature with improvements of the optical properties that is qualified by the optical transmission measurements on the coated cover glass of the modules. The power improvement of the large-scale PV modules shows the increasing about 2.4% at standard condition of the coating technique on average. To improve the AR coating effect of the PV modules, we have characterized the individual PV modules by the measurements of DC power output, modified performance ratio(PRm) and the regression . The results show that the significant improvements of the AR coating effect are 6.4%, 5.5% and 4.5% of increasing of the performances by using the measurements of DC power output, modified performance ratio(PRm) and the regression, respectively.

2006년 공학교육 프로그램 인증평가 예비논평서 분석 연구

강소연(Soyeon Kang),김미경(Mee-Kyoung Kim),김명랑(Myoung Lang Kim),최금진(KeumJin Choi) 한국공학교육학회 2007 공학교육연구 Vol.10 No.1

1999년 한국공학교육인증원이 창립된 이래 2001년 2개 대학의 인증 평가 실시 이후 2005년 현재 전국공 과대학의 10%가 인증 평가가 이루어졌다. 인증기준을 만족시키기 위한 공과대학들의 교육적 노력들을 통해 공학교육인증제도가 한국공학교육을 변화시키고 있는 것이 사실이다. 인증을 준비하는 많은 대학들은 공학교육개선을 위한 통합시스템을 개발하였으며 전국의 50개 이상의 공학교육센터들이 만들어졌다. 또한 학생들에 대한 지속적인 상담과 관찰, 포트폴리오 지도, CQI 등을 통해 공학교육이 개선되고 있음은 매우 고무적이다. 그러나 인증을 준비하는 대학들이 공인원의 인증 평가 기준을 만족시키기 위해 최선의 노력을 하고 있지만 지금까지 유지되어 오던 교육시스템을 수정해야 하는 어려움을 겪고 있다. 더욱이 해마다 공인원의 평가기준이 엄격해 지고 있는 현실에서 이를 준비하는 학교들은 각 기준을 만족하는 수준과 주요 요소들에 대해 분명한 가이드라인을 알고 있지 못하다. 따라서 본 연구는 2006년 인증평가를 받은 4개 종합대학의 예비논평서 분석을 통해 공인원의 인증평가 기준의 주요 요소와 수준을 정리하고 이를 통해 인증을 준비하는 대학들이 최소한 준비해야 할 내용들을 제시하며 공인원이 각 대학에 제시해 주어야 할 요소들을 제언하고자 한다. Though accreditation demands considerable ongoing effort on the part of the college, about 10 percent of Korean engineering colleges has been accredited for 5years by ABEEK. It is true that engineering accreditation contributed the Korean engineering education to improve. Many engineering colleges which had prepared the engineering accreditation developed the integrating system for the engineering education, and over 50 engineering education research centers which assisted to programs in accreditation were founded. Also the faculty commitment to quality programs and excellence in teaching, continuous counseling for students, portfolio guiding and continuous quality improvement(CQI) etc. were performed for accreditation preparation. The engineering colleges preparing accreditation has made efforts for satisfying accreditation criteria, but it is difficult of modifying education systems which have been maintained by now. In addition, engineering colleges need guideline how to satisfy standards. The purpose of this study is to analyze draft statement of 4 universities which were evaluated in 2006 and to suggest the minimal resources for engineering colleges to prepare accreditation.

사우디 아라비아의 태양광 발전량 회귀분석

강소연(Soyeon Kang),오원욱(Wonwook Oh),김주희(Ju-hee Kim),천성일(Sung-Il Chan) 한국신재생에너지학회 2016 한국신재생에너지학회 학술대회논문집 Vol.2016 No.5