Optimization Design of Stainless Steel Stamping Multistage Pump Based on Orthogonal Test

Weidong, Shi,Chuan, Wang,Weigang, Lu,Ling, Zhou,Li, Zhang Korean Society for Fluid machinery 2010 International journal of fluid machinery and syste Vol.3 No.4

Stainless steel stamping multistage pump has become the mainstream of civil multi-stage pump. Combined with the technological features of stamping and welding pump, the studies of design for hydraulic parts of pump were come out. An $L_{18}$($3^7$)orthogonal experiment was designed with seven factors and three values including blade inlet angle, impeller outer diameter, guide vane blade number, etc. 18 plans were designed. The two stage of whole flow field on stainless steel stamping multistage pump at design point for design was simulated by CFD. According to the test result and optimization design with experimental research, the trends of main parameters which affect hydraulic performance were got. After being manufactured and tested, the efficiency of the optimal model pump reaches 61.36% and the single head is more than 4.8 m. Compared with the standard efficiency of 53%, the design of the stainless steel stamping pump is successful. The result would be instructive to the design of Stainless steel stamping multistage pump designed by the impeller head maximum approach.

Objective Evaluation of Fabric Wrinkles Based on 2-D Gabor Transform

Kangjun Shi,Jingan Wang,Lei Wang,Ruru Pan,Weidong Gao 한국섬유공학회 2020 Fibers and polymers Vol.21 No.9

In order to establish an objective, stable and efficient wrinkle evaluation system for fabric wrinkle evaluation, amethod based on 2-D Gabor transform was proposed. Among this system, the directions of Gabor filter were determinedaccording to the range of amplitude response. Then a set of Gabor filters were obtained by selecting and optimizing thecentral frequency, the half peak bandwidth and the shape factor of the Gaussian surface. After Gabor transform by such filterbank, the amplitudes of different response spectrums were extracted, constructing a multi-dimensional feature vector. Finally,the feature vectors of the fabric image samples, whose wrinkle degrees were evaluated manually in advance, were extractedand used to train a support vector machine (SVM), which achieved 81.82 % evaluation accuracy on the 345 samples. Thetrained SVM was applied to evaluate the wrinkle degree of the fabric samples acquired in different illumination directions,and verified the stability of the proposed method to illumination environment. Compared with the existing method, theproposed method has higher classification accuracy. The comparison results indicate the Gabor amplitude feature proposedby this research has a high correlation with the fabric wrinkle grades.

alpha-MSH prevents impairment in renal function and dysregulation of AQPs and Na-K-ATPase in rats with bilateral ureteral obstruction.

Li, Chunling,Shi, Yimin,Wang, Weidong,Sardeli, Chrysanthi,Kwon, Tae-Hwan,Thomsen, Klaus,Jonassen, Thomas,Djurhuus, Jens Christian,Knepper, Mark A,Nielsen, Soren,Frokiaer, Jorgen American Physiological Society 2006 American Journal of Physiology Vol.290 No.2

<P>The purpose of this study was to evaluate the effects of the anti-inflammatory hormone alpha-melanocyte-stimulating hormone (alpha-MSH) treatment on renal function and expression of aquaporins (AQPs) and Na-K-ATPase in the kidney in response to 24 h of bilateral ureteral obstruction (BUO) or release of BUO (BUO-R). In rats with 24-h BUO, immunoblotting revealed that downregulation of AQP2 and AQP3 was attenuated (AQP2: 38 +/- 5 vs. 13 +/- 4%; AQP3: 44 +/- 3 vs. 19 +/- 4% of sham levels; P < 0.05), whereas downregulation of Na-K-ATPase was prevented by alpha-MSH treatment (Na-K-ATPase: 94 +/- 7 vs. 35 +/- 5% of sham levels; P < 0.05). Immunocytochemistry confirmed the changes in AQP1 and Na-K-ATPase expression. Renal tubular cell apoptosis was confirmed in BUO kidneys, and alpha-MSH treatment virtually completely abolished apoptosis. Furthermore, we measured glomerular filtration rate (GFR) and effective renal plasma flow (ERPF), respectively. Forty-eight hours after BUO-R demonstrated that alpha-MSH treatment almost completely prevented the decrease in GFR (nontreated: 271 +/- 50; alpha-MSH: 706 +/- 85; sham: 841 +/- 105 microl x min(-1).100 g body wt(-1), P < 0.05) and ERPF (nontreated: 1,139 +/- 217; alpha-MSH: 2,598 +/- 129; sham: 2,633 +/- 457 microl x min(-1).100 g body wt(-1), P < 0.05). alpha-MSH treatment also partly prevented the downregulation of AQP1 and Na-K-ATPase expression in rats after BUO-R for 48 h. In conclusion, alpha-MSH treatment significantly prevents impairment in renal function and also prevents downregulation of AQP2, AQP3, and Na-K-ATPase during BUO or AQP1 and Na-K-ATPase after BUO-R, demonstrating a marked renoprotective effect of alpha-MSH treatment in conditions with urinary tract obstruction.</P>

Nanoscale cryptography: opportunities and challenges

Masoumi Massoud,Shi Weidong,Xu Lei 나노기술연구협의회 2015 Nano Convergence Vol.2 No.21

While most of the electronics industry is dependent on the ever-decreasing size of lithographic transistors, this scaling cannot continue indefinitely. To improve the performance of the integrated circuits, new emerging and paradigms are needed. In recent years, nanoelectronics has become one of the most important and exciting forefront in science and engineering. It shows a great promise for providing us in the near future with many breakthroughs that change the direction of technological advances in a wide range of applications. In this paper, we discuss the contribution that nanotechnology may offer to the evolution of cryptographic hardware and embedded systems and demonstrate how nanoscale devices can be used for constructing security primitives. Using a custom set of design automation tools, it is demonstrated that relative to a conventional 45-nm CMOS system, performance gains can be obtained up to two orders of magnitude reduction in area and up to 50 % improvement in speed.

Numerical calculation and optimization designs in engine cooling water pump

Li Wei,Wang Chuan,Shi Weidong,Zhao Xiaofan,Yang Yongfei,Pei Bing 대한기계학회 2017 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.31 No.5

The cavitation damage in the Engine cooling water pump (ECWP) is the key factor that shortens the lifespan of automobile cooling systems, and causes vibration and noise. To improve cavitation performance and external characteristics of ECWP, three optimized models were designed on the basis of WP7 diesel ECWP. The whole flow fields in three models and the prototype pump were numerically simulated, employing the time averaged Navier-Stokes equation, the standard k-ε turbulent model and Zwart-Gerber-Belamri multiphase flow model by ANSYS-CFX software. Pressure distribution, turbulent kinetic energy distribution, bubble volume fraction distribution, external characteristics and cavitation performance of the prototype pump and optimized models were compared and analyzed. The results show that the external characteristics and cavitation performance of the optimized models are significantly better than that in the prototype pump. Through decreasing the inlet blade angle and wrap angle, extending the blade to inlets and extending a certain inclination in the blade, shock loss in blade inlet was reduced and so, the performance of pump will be improved. The flow condition at blade inlet will also be improved greatly, which in turn improves cavitation performance. When reducing the quantity of blades, the excretion coefficient will drop, flow area of blade inlet becomes bigger, but head has a little drop. And the pump optimized by reducing the quantity of blades has the optimal cavitation performance among three optimized models. With the decrease of impeller diameter, the absolute pressure in the critical cavitation point becomes bigger, the inlet bubble volume fraction at the same absolute pressure increases while cavitation performance gets worse. The obtained numerical results were compared with the experimental ones, and the outcome showed the same tendency between the two along with acceptable error.

Cell Division Cycle Associated 8 Is a Key Regulator of Tamoxifen Resistance in Breast Cancer

Dehai Yu,Libo Shi,Yuhui Bu,Weidong Li 한국유방암학회 2019 Journal of breast cancer Vol.22 No.2

Purpose: Breast cancer (BC) is one of the most common malignancies globally, and millions of women worldwide are diagnosed with BC every year. Up to 70% of BC patients are estrogen receptor (ER)-positive. Numerous studies have shown that tamoxifen has a significant therapeutic effect on both primary and metastatic ER-positive BC patients. Although tamoxifen is currently one of the most successful therapeutic agents for BC, a significant proportion of patients will eventually become resistant to tamoxifen, leading to tumor recurrence and metastasis. Knowledge about the development of tamoxifen resistance in BC patients is still limited. Methods: We applied a loss-and-gain method to study the biological functional role of cell division cycle associated 8 (CDCA8) in tamoxifen resistance in BC cells. Results: We found that CDCA8 was significantly elevated in tamoxifen-resistant BC cells. Knockdown of CDCA8 expression significantly inhibited the proliferation of tamoxifen-resistant BC cells and reduced their resistance to tamoxifen. In contrast, overexpression of CDCA8 promoted the growth of tamoxifen-sensitive BC cells and induced their resistance to tamoxifen. Conclusion: In this study, we reported that CDCA8 is a key regulator of tamoxifen resistance in BC, suggesting that CDCA8 may serve as a potential therapeutic target for BC treatment.

PRECURSORS-DECOMPOSITED SYNTHESIS AND VISIBLE-LIGHT-RESPONSE PHOTOCATALYSTIC PROPERTIES OF UNIFORM POROUS Bi 2 O 3 NANOSPHERES

XIAOLI SUN,JIANGGUO GUAN,WEIDONG SHI,HAO TU,LEILEI XU,YAN YAN 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2014 NANO Vol.9 No.6

The Bi 2 O 3 sphere-like precursors were ¯rst synthesized through a simple hydrothermal reactionin the mixture of sodium cholate (SC) and hydrogen peroxide. Thermal decomposition of theseprecursors would result in the formation of the uniform porous Bi 2 O 3 nanospheres with diametersof ca. 80 nm in air at 500?C. The amount of added H 2 O 2 and the reaction time were found to playimportant roles in the formation of Bi 2 O 3 sphere-like precursors. The as-prepared porous Bi 2 O 3nanospheres exhibited a very excellent photocatalytic activity for the degradation of rhodamineB (RB) and methyl blue (MB) dyes under visible-light irradiation, which could be attributed totheir narrow band gap and high surface area.

Design and performance research of a mixed-flow submersible deep well pump

Zhang, Qihua,Xu, Yuanhui,Cao, Li,Shi, Weidong,Lu, Weigang Korean Society for Fluid machinery 2016 International journal of fluid machinery and syste Vol.9 No.3

To meet the demand of higher handling capacity, a mixed-flow submersible deep well pump was designed and tested. The main hydraulic components are made of plastics, which is free of erosion, light-weight, and environment-friendly. To simplify plastic molding process, and to improve productivity, an axial-radial guide vane was proposed. To clarify its effect on the performance, a radial guide vane and a space guide vane are developed as well. By comparison, the efficiency of the pump equipped with the axial-radial guide vane is higher than the radial guide vane and is lower than the space guide vane, and its high efficiency range is wide. The static pressure recovery of the axial guide vane is a bit lower than the space guide vane, but it is much larger than the radial guide vane. Taking the cost and molding complexity into consideration, the axial-radial guide vane is much economic, promoting its popularity for the moderate and high specific speed submersible deep well pumps.

Design and performance research of a mixed-flow submersible deep well pump

Qihua Zhang,Yuanhui Xu,Li Cao,Weidong Shi,Weigang Lu 한국유체기계학회 2016 International journal of fluid machinery and syste Vol.9 No.3

To meet the demand of higher handling capacity, a mixed-flow submersible deep well pump was designed and tested. The main hydraulic components are made of plastics, which is free of erosion, light-weight, and environment-friendly. To simplify plastic molding process, and to improve productivity, an axial-radial guide vane was proposed. To clarify its effect on the performance, a radial guide vane and a space guide vane are developed as well. By comparison, the efficiency of the pump equipped with the axial-radial guide vane is higher than the radial guide vane and is lower than the space guide vane, and its high efficiency range is wide. The static pressure recovery of the axial guide vane is a bit lower than the space guide vane, but it is much larger than the radial guide vane. Taking the cost and molding complexity into consideration, the axial-radial guide vane is much economic, promoting its popularity for the moderate and high specific speed submersible deep well pumps.

Evaluation of an Immune-privileged Scaffold for In vivo Implantation of Tissue-engineered Trachea

Shu Pan,Fei Sun,Hongcan Shi,Fangbiao Zhang,Xingchen Liu,Weidong Zhang 한국생물공학회 2014 Biotechnology and Bioprocess Engineering Vol.19 No.5

Forty tracheas were harvested from donor NewZealand rabbits. Thirty of the tracheas were randomlydivided into four treatment groups corresponding to 4, 5, 6,or 7% NaClO4 and one untreated group (n = 6 each group). Scanning electron microscopy distinctly revealed thecilium of epithelial cells in the fresh trachea. The internalsurface of the trachea was rough in the 4% treatment groupand smooth in the 5% treatment group, whereas the matrixwas fractured in the 6% treatment group and highlyfractured in the 7% treatment group. We observed that thenumber of nuclei in the cells of the 4, 5, 6, and 7%treatment groups decreased compared to the cells of theuntreated group (p < 0.05). Although there was a significantdecrease in maximum tensile strength, tensile strain atfracture and the elastic modulus (p < 0.05) with increasingconcentrations of NaClO4, the content of glycosaminoglycans(GAGs) did not significantly decline (p > 0.05) in the 5%treatment group. In addition, histopathological analysisshowed that the fiber component and basement membraneof the matrix in the 5% treatment group were retained afteroptimal decellularization. Despite the preserved cartilage,in vitro immunohistochemical analysis revealed that thematrix did not show the presence of major histocompatibilitycomplex (MHC) antigens. The remaining ten donor tracheas,which were divided into a positive control group and anoptimal decellularized group, were used for allogeneictransplantation. Blood samples were taken regularly, andhistologic examinations were performed at 30 days postimplantation,which showed no significant immune rejection. In conclusion, we surveyed the structural integrity throughmorphological observation and compared the biomechanicaland immunogenic changes in the tracheal matrix under thedifferent treatments. The optimal decellularized trachealmatrix with preserved cartilage, which was acquired via 5%NaClO4 treatment, exhibited structural integrity, antigen cellremoval and immune privilege and would be suitable for useas a tissue-engineered trachea for in vivo transplantation inrabbit models.