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Xue Xu,Yue-sheng Huang,Qiong Zhang,Jiong-yu Hu,Dong-xia Zhang2,Xu-pin Jiang,jie-zhi Jia,Jing-ci Zhu 한국분자세포생물학회 2013 Molecules and cells Vol.36 No.4
Hypoxia-induced microtubule disruption and mitochondrial permeability transition (mPT) are crucial events leading to fatal cell damage and recent studies showed that microtubules (MTs) are involved in the modulation of mitochondrial function. Dynein light chain Tctex-type 1 (DYNLT1) is thought to be associated with MTs and mitochondria. Previously we demonstrated that DYNLT1 knockdown aggravates hypoxia-induced mitochondrial permeabilization, which indicates a role of DYNLT1 in hypoxic cytoprotection. But the underlying regulatory mechanism of DYNLT1 remains illusive. Here we aimed to investigate the phosphorylation alteration of DYNLT1 at serine 82 (S82) in hypoxia (1% O2). We therefore constructed recombinant adenoviruses to generate S82E and S82A mutants, used to transfect H9c2 and HeLa cell lines. Development of hypoxia-induced mPT (MMP examining, Cyt c release and mPT pore opening assay), hypoxic energy metabolism (cellular viability and ATP quantification), and stability of MTs were examined. Our results showed that phosph-S82 (S82-P) expression was increased in early hypoxia; S82E mutation (phosphomimic) aggravated mitochondrial damage, ele-vated the free tubulin in cytoplasm and decreased the cellular viability; S82A mutation (dephosphomimic) seemed to diminish the hypoxia-induced injury. These data suggest that DYNLT1 phosphorylation at S82 is involved in MTs and mitochondria regulation, and their interaction and cooperation contribute to the cellular hypoxic tolerance. Thus, we provide new insights into a DYNLT1 mechanism in stabilizing MTs and mitochondria, and propose a potential therapeutic target for hypoxia cytoprotective studies.
Sheng-hai Zhang,Ying-zi Wang,Fan-yun Meng,You-lin Li,Cai-xia Li,Fei-peng Duan,Qing Wang,Xiu-ting Zhang,Chun-ni Zhang 대한약학회 2015 Archives of Pharmacal Research Vol.38 No.5
Flavonoid glycosides are metabolized byintestinal bacteria, giving rise to a wide range of phenolicacids that may exert systemic effects in the body. Themicrobial metabolism of flavonoids extracted from theleaves of Diospyros kaki (FLDK) by intestinal bacteria wasinvestigated in vitro. High-performance liquid chromatography/linear trap quadrupole orbitrap mass spectrometrywas performed to analyze the metabolites of flavonoidsin vivo using Xcalibur2.1 software. The results showed thatthe levels of flavonoid glycosides and flavonoid aglyconesdecreased rapidly in the process of microbial metabolismby intestinal bacteria in vitro, and the metabolic rate maybe related to the concentration of intestinal bacteria in theculture solution. In vivo metabolites of FLDK weredetected in rat plasma and urine after oral administration ofFLDK. Eight flavonoids were identified in the urine, andthree were identified in the plasma; however, flavonoidaglycones were not found in the plasma.
Revision of the spider genus Taira (Araneae, Amaurobiidae, Amaurobiinae)
Zhi-Sheng Zhang,Ming-Sheng Zhu,Da-Xiang Song 한국거미연구소 2008 한국거미 Vol.24 No.2
The cribellate amaurobiid genus Taira, which is suggested to be most similar to the genus Amaurobius and someother related genera, is revised based on genital characters. Eight species, one from Japan and seven from China, areincluded. Five new species from China are described: T. cangshan, T. concava, T. latilabiata, T. obtusa, and T. sulciformis.Titanoeca decorata Yin & Bao 2001 is newly transferred to this genus and its male is described for the first time. Tairalunaris Wang & Ran 2004 is newly synonymized with T. liboensis Zhu, Chen & Zhang 2004.
Two New Species of the Genus Allozelotes Yin & Peng, 1998 (Araneae, Gnaphosidae) from China
Yang Zi-Zhong, Zhang Zi-Sheng, Zhang Yao-Guang, Joo Pil Kim(김주필) 한국거미연구소 2009 한국거미 Vol.25 No.1-2
중국 Yunnan 지역에서 채집한 수리거미과의 Allozelotes 속의 2 신종을 기재하여 보고하는 바이다. 즉 Allozelotes songi sp. nov.와 A. microsaccatus sp. nov. 이다. 표본은 SWUC와 CDLC에 보관한다. 측정치는 millimeters이다. Two new species of the genus Allozelotes collected from Yunnan, China, are described and illustrated: Allozelotes songi sp. nov. and A. microsaccatus sp. nov. Type specimens are respectively deposited in School of Life Science, Southwest University(SWUC) and College of Life Science and Chemistry, Dali University(CDLC). All measurements given are in millimeters.
Pore structure evolution characteristics of sandstone uranium ore during acid leaching
Sheng Zeng,Yuan Shen,Bing Sun,Ni Zhang,Shuwen Zhang,Song Feng 한국원자력학회 2021 Nuclear Engineering and Technology Vol.53 No.12
To better understand the permeability of uranium sandstone, improve the leaching rate of uranium, andexplore the change law of pore structure characteristics and blocking mechanism during leaching, wesystematically analyzed the microstructure of acid-leaching uranium sandstone. We investigated thevariable rules of pore structure characteristics based on nuclear magnetic resonance (NMR). The resultsshowed the following: (1) The uranium concentration change followed the exponential law duringuranium deposits acid leaching. After 24 h, the uranium leaching rate reached 50%. The uranium leachingslowed gradually over the next 4 days. (2) Combined with the regularity of porosity variation, Stages Iand II included chemical plugging controlled by surface reaction. Stage I was the major completion phaseof uranium displacement with saturation precipitation of calcium sulfate. Stage II mainly precipitatediron (III) oxide-hydroxide and aluminum hydroxide. Stage III involved physical clogging controlled bydiffusion. (3) In the three stages of leaching, the permeability of the leaching solution changed with thepore structure, which first decreased, then increased, and then decreased
Zhang, Sheng East-Asian Society for Urban History 2020 Journal of east-asian urban history Vol.2 No.1
Since 1949, The first generation leader MAO zedong liked reading history books and historical biography, It led to criticism and evaluation of history and character be targeted in every movement, before the February Outline(er yue ti gang) had been revoked, the Shanghai society discussed "Hai Rui's Dismissal "basically" within the "learning and using Chairman MAO's works(huo xue huo yong mao zhu xi zhu zuo)" category, with the deterioration of the national political situation, based on the historical drama "Hai Rui's Dismissal" discussions, the dilemma of cultural propaganda and academic research appeared.
Conceptual Graph Matching Method for Reading Comprehension Tests
Zhang, Zhi-Chang,Zhang, Yu,Liu, Ting,Li, Sheng The Korea Institute of Information and Commucation 2009 Journal of information and communication convergen Vol.7 No.4
Reading comprehension (RC) systems are to understand a given text and return answers in response to questions about the text. Many previous studies extract sentences that are the most similar to questions as answers. However, texts for RC tests are generally short and facts about an event or entity are often expressed in multiple sentences. The answers for some questions might be indirectly presented in the sentences having few overlapping words with the questions. This paper proposes a conceptual graph matching method towards RC tests to extract answer strings. The method first represents the text and questions as conceptual graphs, and then extracts subgraphs for every candidate answer concept from the text graph. All candidate answer concepts will be scored and ranked according to the matching similarity between their sub-graphs and question graph. The top one will be returned as answer seed to form a concise answer string. Since the sub-graphs for candidate answer concepts are not restricted to only covering a single sentence, our approach improved the performance of answer extraction on the Remedia test data.
Sheng Sheng,Xiaorui Zhang,Yu Zheng,Jiao Wang,Yu Zhou,Chengwu Liao,Jun Wang,Fu-an Wu 한국응용곤충학회 2019 Journal of Asia-Pacific Entomology Vol.22 No.1
The effects of six sugar resources (fructose, glucose, sucrose, trehalose, raffinose and honey) on the longevity, oviposition performance and nutrition levels of Meteorus pulchricornis, a thelytokous larval endoparasitoid of the common cutworm Spodoptera litura were examined under laboratory conditions. Female adults of M. pulchricornis fed 1 M fructose, glucose, trehalose or sucrose solutions survived longer than those fed on other sugar solutions or water. When provided with honey or sucrose solutions, the female parasitoids laid more offspring than those fed other sugar diets or the control. The body size of offspring driven from honey-, fructose-, sucrose-, and glucose-fed females, along with water-fed group, were larger than the trehalose- and raffinose-fed females. However, the emergence rates of all offspring generated from different sugars- and water-fed females were similar. When separately given honey, sucrose or fructose, M. pulchricornis females accumulated fructose at a higher level than the other groups. Parasitoid wasps fed trehalose solution accumulated the highest level of total sugar. Glycogen levels and lipid content were highest at emergence and then decreased across all diets. In addition, females fed on trehalose had the highest level of glycogen compared to other sugar diets and water control regardless of emergency level. Females fed trehalsoe, fructose, and glucose solutions had a higher level of lipid than those fed other sugar solutions and water at life end. The outcome of this study can benefit both laboratory rearing and management interventions that improve sugar sources for the parasitoid in the field.
RANKS OF SUBMATRICES IN A GENERAL SOLUTION TO A QUATERNION SYSTEM WITH APPLICATIONS
Zhang, Hua-Sheng,Wang, Qing-Wen Korean Mathematical Society 2011 대한수학회보 Vol.48 No.5
Assume that X, partitioned into $2{\times}2$ block form, is a solution of the system of quaternion matrix equations $A_1XB_1$ = $C_1,A_2XB_2=C_2$. We in this paper give the maximal and minimal ranks of the submatrices in X, and establish necessary and sufficient conditions for the submatrices to be zero, unique as well as independent. As applications, we consider the common inner inverse G, partitioned into $2{\times}2$ block form, of two quaternion matrices M and N. We present the formulas of the maximal and minimal ranks of the submatrices of G, and describe the properties of the submatrices of G as well. The findings of this paper generalize some known results in the literature.