기획주제(企劃主題) : 동아시아 한자(漢字),한자교육(漢字敎育)의 현황(現況)과 과제(課題); 漢字結構分析的曆史演變 -試論六書、偏旁與部件之更替

( Zheng Yu Shi ) 한국한자한문교육학회 2013 漢字 漢文敎育 Vol.30 No.-

한자의 구조 분석 중 육서와 편방, 부건의 구체적 함의와 상호 관계 등의 문제는 항상 한자의 이론 연구와 교육 실천에 있어서 어려운 문제였다. 필자는 어떠한구조 분석법이라도 모두가 상상에서 나온 것이 아니라, 육서와 편방, 부건의 출현이 한자의 변천 과정 중 몇 차례 있었던 대변화의 시기와 맞물려 있다고 생각하여, 이 문제들을 이해하는데 도움을 주고자 하였다. 이를 위해 필자는 한자 발전의 각도에서 이 세 가지 용어의 기원과 발전 맥락을 분석하고, 이와 함께 이 세 가지가 내포하고 있는 함의와 관계에 대해 정리하였다. The author of this paper combined the six categories of Chinese characters, radicals, components and the evolution of Chinese characters font to investigate the difference between the three and their inner links based on the diachronic analysis method and drew the following conclusions: The six categories of Chinese characters, radicals and components were three different structure analysis methods used on different font during the different historical period of the Chinese characters font evolution. The six categories of Chinese characters was the one of the three methods which was created by a man whose surname was Bao in Zhou dynasty to analyse the ancient Chinese character structure so that can let the temporal students initiate Chinese characters; The radicals were obtained from the disposable analysis of temporal font of the period from the official script to the regular script; The components came from the multiple stereoscopic segmentation of Chinese characters, which are the ways to simplify them and process their information. The six categories of Chinese characters, radicals and the components are relatively independent and have some certain gradualism and inheritance as well.

High optical quality polycrystalline indium phosphide grown on metal substrates by metalorganic chemical vapor deposition

Zheng, Maxwell,Yu, Zhibin,Joon Seok, Tae,Chen, Yu-Ze,Kapadia, Rehan,Takei, Kuniharu,Aloni, Shaul,Ager, Joel W.,Wu, Ming,Chueh, Yu-Lun,Javey, Ali American Institute of Physics 2012 JOURNAL OF APPLIED PHYSICS - Vol.111 No.12

The differences between copper sulfate and tribasic copper chloride on growth performance, redox status, deposition in tissues of pigs, and excretion in feces

Zheng, Ping,Pu, Bei,Yu, Bing,He, Jun,Yu, Jie,Mao, Xiangbing,Luo, Yuheng,Luo, Junqiu,Huang, Zhiqing,Luo, Chenggui,Wang, Shaohui,Chen, Daiwen Asian Australasian Association of Animal Productio 2018 Animal Bioscience Vol.31 No.6

Objective: The objective of this experiment was to compare the effects of adding 130 mg/kg Cu from either copper sulfate (CS) or tribasic copper chloride (TBCC) on growth performance, mineral deposition in tissues, and the excretion in feces of pigs as well as changes in the mineral contents in tissues and feces when the supplemental Cu level was decreased from 130 mg/kg to 10 mg/kg. Methods: A total of 72 pigs ($32.6{\pm}1.2kg$) were randomly assigned to a CS diet or a TBCC diet with 6 pens per treatment. The trial lasted 102 d and included 3 phases (phase 1, 1 to 30 d; phase 2, 31 to 81 d; and phase 3, 82 to 102 d). The supplemental levels of Cu in the 2 treatments were 130 mg/kg in phase 1 and 2 and 10 mg/kg in phase 3. Results: The results showed that pigs fed the CS diet tended to have higher average daily gain than pigs fed the TBCC diet during d 1 to 81 (p<0.10). Compared with CS, TBCC increased the activities of aspartate transaminase (AST), ceruloplasmin, and superoxide dismutase in serum on d 30 (p<0.05). The TBCC decreased the Cu level in the liver on d 81 (p<0.05) and increased the Mn level in the liver on d 102 (p<0.05). The concentration of Cu in feces sharply decreased when the supplemental Cu level in diet changed from 130 mg/kg to 10 mg/kg in both diets (p<0.05). Conclusion: The result suggested that TBCC and CS had no significant difference on growth performance but TBCC had higher activities of AST and antioxidant enzymes and lower liver Cu than CS when pigs fed diets with 130 mg Cu /kg diet.

Research on the Influence of “Filtering Bubbles” on Short Video Algorithm Mechanism-Taking Tiktok as an Example

Yu Zheng,Dong-hyuk Choi 한국콘텐츠학회 2021 한국콘텐츠학회 ICCC 논문집 Vol.2021 No.12

Evaluation of antimicrobial activity of water-soluble flavonoids extract from Vaccinium bracteatum Thunb. leaves

Yu Zheng,Lin Chen,Yanhua Liu,Lei Shi,Shoupeng Wan,Li Wang 한국식품과학회 2019 Food Science and Biotechnology Vol.28 No.6

Aqueous extract of Vaccinium bracteatumThunb. leaves (VWFE) is traditionally used for foodpreservation in China, which is rich in flavonoids compounds. VWFE could effectively inhibit the growth of bothGram negative (Escherichia coli) and positive bacteria(Staphylococcus aureus and Bacillus subtilis), however, noinhibition effects were observed on mold and yeast. Theminimum inhibitory concentration of VWFE were2.06 mg/ml, 1.03 mg/ml, and 4.11 mg/ml for E. coli, S. aureus and B. subtilis, respectively, which were 13%, 13%,and 26% of sodium benzoate and 23%, 11%, and 46% ofpotassium sorbate. Cell membrane permeability assaysindicated that cell membrane disruption was one of theantibacterial mechanisms of VWFE. VWFE showed a goodthermal stability. The expiration date of VWFE was6 months at 25 C, which was predicted using the acceleratedaging method. This present work indicated

Two-dimensional heat transfer modeling of high-end loudspeakers with the periodic oscillations of convex dust caps

Zheng Yu GAO,Hye-Mi JUNG,Sukkee UM 대한기계학회 2014 대한기계학회 춘추학술대회 Vol.2014 No.4-3

Human lactoferrin efficiently targeted into caprine beta-lactoglobulin locus with transcription activator-like effector nucleases

Yu-Guo Yuan,Shao-Zheng Song,Meng-Ming Zhu,Zheng-Yi He,Rui Lu,Ting Zhang,Fei Mi,Jin-Yu Wang,Yong Cheng 아세아·태평양축산학회 2017 Animal Bioscience Vol.30 No.8

Objective: To create genetically modified goat as a biopharming source of recombinant human lacotoferrin (hLF) with transcription activator-like effector nucleases. Methods: TALENs and targeting vector were transferred into cultured fibroblasts to insert hLF cDNA in the goat beta-lactoglobulin (BLG) locus with homology-directed repair. The gene targeted efficiency was checked using sequencing and TE7I assay. The bi-allelic gene targeted colonies were isolated and confirmed with polymerase chain reaction, and used as donor cells for somatic cell nuclear transfer (SCNT). Results: The targeted efficiency for BLG gene was approximately 10%. Among 12 Bi-allelic gene targeted colonies, five were used in first round SCNT and 4 recipients (23%) were confirmed pregnant at 30 d. In second round SCNT, 7 (53%), 4 (31%), and 3 (23%) recipients were confirmed to be pregnant by ultrasound on 30 d, 60 d, and 90 d. Conclusion: This finding signifies the combined use of TALENs and SCNT can generate bi-allelic knock-in fibroblasts that can be cloned in a fetus. Therefore, it might lay the foundation for transgenic hLF goat generation and possible use of their mammary gland as a bioreactor for large-scale production of recombinant hLF.

Expression of the Transgene is Consistently Inherited to High Numbers of Generations and Independent on Its Source

Zheng, Zhen-Yu,Oh, Keon-Bong,Koo, Deog-Bon,Han, Yong-Mahn,Lee, Kyung-Kwang The Korean Society of Animal Reproduction 2008 Reproductive & developmental biology Vol.32 No.1

Most studies on transgenic bioreactors have focused on expression levels of interest genes. In this study we examined whether transgenic bioreactors would inherit expression level of the Oansgene to long-term generations independently of transgene sources. We employed three transgenic mice, which were separately reported, carrying different transgenes and copy numbers, 27 kb of hLF and 22 kb of hIL-10 genomic sequences, and 1.3 kb of hTPO cDNA, respectively. Three females of the transgenic lineages crossbred with a wild-type male up to 20 generations to test transgenic frequencies of their progenies and to determine expression levels of the transgenes. Ultimately, transmission rates of kLF, hIL-10, and hTPO were $64.3{\pm}7.0$, $59.3{\pm}9.8$, and $56.1{\pm}9.7$, respectively, appeared following Mendelian pattern of inheritance. Notably, we found that levels of expressions of hLF, hIL-10, and hTPO in milk were sustained to high numbers of generations. No transgene silencing of expression was observed in every generations of all transgenic mice. In conclusion, we suggest that once established animal bioreactors could consistently transmit the transgene to continual generations, without loss of expressional activity, independently of transgene sources.

Intranasal administration of oxytocin attenuates stress responses following chronic complicated stress in rats.

Yu Yang,Haijie Yu,Reji Babygirija,Bei Shi,Weinan Sun,Xiaojiao Zheng,Jun Zheng 대한소화기 기능성질환∙운동학회 2019 Journal of Neurogastroenterology and Motility (JNM Vol.25 No.4

Background/Aims Gastrointestinal (GI) symptoms may develop when we fail to adapt to various stressors of our daily life. Central oxytocin (OXT) can counteract the biological actions of corticotropin-releasing factor (CRF), and in turn attenuates stress responses. Administration (intracerebroventricular) of OXT significantly antagonized the inhibitory effects of chronic complicated stress (CCS) on GI dysmotility in rats. However, intracerebroventricular administration is an invasive pathway. Intranasal administration can rapidly deliver peptides to the brain avoiding stress response. The effects of intranasal OXT on hypothalamus-pituitary-adrenal axis and GI motility in CCS conditions have not been investigated. Methods A CCS rat model was set up, OXT 5, 10, or 20 μg were intranasal administered, 30 minutes prior to stress loading. Central CRF and OXT expression levels were analyzed, serum corticosterone and OXT concentrations were measured, and gastric and colonic motor functions were evaluated by gastric emptying, fecal pellet output, and motility recording system. Results Rats in CCS condition showed significantly increased CRF expression and corticosterone concentration, which resulted in delayed gastric emptying and increased fecal pellet output, attenuated gastric motility and enhanced colonic motility were also recorded. OXT 10 μg or 20 μg significantly reduced CRF mRNA expression and the corticosterone concentration, OXT 20 μg also helped to restore GI motor dysfunction induced by CCS. Conclusion Intranasal administration of OXT has an anxiolytic effect and attenuates the hypothalamus-pituitary-adrenal axis in response to CCS, and gave effects which helped to restore GI dysmotility, and might be a new approach for the treatment of stress-induced GI motility disorders. Background/Aims Gastrointestinal (GI) symptoms may develop when we fail to adapt to various stressors of our daily life. Central oxytocin (OXT) can counteract the biological actions of corticotropin-releasing factor (CRF), and in turn attenuates stress responses. Administration (intracerebroventricular) of OXT significantly antagonized the inhibitory effects of chronic complicated stress (CCS) on GI dysmotility in rats. However, intracerebroventricular administration is an invasive pathway. Intranasal administration can rapidly deliver peptides to the brain avoiding stress response. The effects of intranasal OXT on hypothalamus-pituitary-adrenal axis and GI motility in CCS conditions have not been investigated. Methods A CCS rat model was set up, OXT 5, 10, or 20 μg were intranasal administered, 30 minutes prior to stress loading. Central CRF and OXT expression levels were analyzed, serum corticosterone and OXT concentrations were measured, and gastric and colonic motor functions were evaluated by gastric emptying, fecal pellet output, and motility recording system. Results Rats in CCS condition showed significantly increased CRF expression and corticosterone concentration, which resulted in delayed gastric emptying and increased fecal pellet output, attenuated gastric motility and enhanced colonic motility were also recorded. OXT 10 μg or 20 μg significantly reduced CRF mRNA expression and the corticosterone concentration, OXT 20 μg also helped to restore GI motor dysfunction induced by CCS. Conclusion Intranasal administration of OXT has an anxiolytic effect and attenuates the hypothalamus-pituitary-adrenal axis in response to CCS, and gave effects which helped to restore GI dysmotility, and might be a new approach for the treatment of stress-induced GI motility disorders.

Co-expression of Human Proteins (IL-10, TPO and/or Lactoferrin) into Milk of Cross-Breed Transgenic Mouse

Zheng, Zhen-Yu,Lee, Hyo-Sang,Oh, Keon-Bong,Koo, Deog-Bon,Han, Yong-Mahn,Lee, Kyung-Kwang The Korean Society of Animal Reproduction 2008 Reproductive & developmental biology Vol.32 No.1

We have previously produced transgenic (TG) mice expressing the human lactoferrin (hLF), interleukin-10 (hIL-10), and thrombopoietin (hTPO) proteins in the milk. In this study, we examined whether simple crossbreeding between two kids of a single transgenic mouse can produce double transgenics co-expressing two human proteins.. The hLF male, and the hIL-10 male were crossbred with the hIL-10 and hTPO females, and the hTPO female, respectively. PCR analysis for genotyping showed 32%, 23% and 24% double transgenic rates for hLF/hIL-10, hLF/hTPO, and hIL-10/hTPO transgenes, respectively. We analyzed the expression levels of the human proteins from double transgenic mice and compared those with their single transgenic siblings. All double transgenic co-expressed two human proteins at comparable levels to singles', unless hTPO was not co-expressed: for hLF, 1.1 mg/ml in hLF/hIL-10, whereas 0.5 mg/ml in hLF/hTPO; for hIL-10, 4.1 mg/ml in hIL-10/hLF, whereas 1.4 mg/ml in hIL-10/hTPO. Ihe downregulation of hTPO to half level of singles' was observed in double transgenic mice. The possible reason why hTPO co-expressed might lead to down-regulation of another human protein was discussed. These results suggested that double transgenic generated by crossbreeding between two singles' could be useful system for bioreactor.