Effect of Cu on Pore Structure of Al–Si Foam

Fan Deng,Jianzhong Fan,Yanqiang Liu,Xuehan Lu,Shaohua Wei,Junhui Nie 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.12

The alloy composition is an important factor effecting the pore structure of aluminum foam. In this paper, the powder compactfoaming method was used, and different content of Cu element powders were added to the alloy Al–9Si, for investigatingthe effect of alloying element on foaming process. With the Cu content of Al–Si–Cu alloy increasing, the expansion ratio isincreased, the time required to reach maximum expansion is shortened, and the number of fissure-like pores at early foamingstage is decreased. This improving action is related to the higher volume fraction of liquid phase in same melting temperaturecaused by increasing Cu content in alloy. Comparing different Al–Si–Cu alloys with different Cu content at same expansionratio, the higher Cu content, the smaller pore size and the thinner cell wall. This beneficial effect on pore structure is attributedto the addition of Cu that is benefit to increasing the viscosity of Al–Si–Cu alloy during foaming. And at same expansionrate, the more content of Cu in Al–Si–Cu alloy, the higher compressive strength of aluminum foam.

Catalytic oxidation of biomass derived 5-hydroxymethylfurfural (HMF) over RuIII-incorporated zirconium phosphate catalyst

Fan Wang,Ziliang Yuan,Bing Liu,Shaohua Chen,Zehui Zhang 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.38 No.-

In this study, a new ruthenium catalyst was used for the oxidation of biomass derived5-hydroxymethylfurfural (HMF) under mild conditions, which was prepared by the exchange of Ru3+with H+ in the structure of the zirconium phosphate (ZrP). The as-prepared ZrP–Ru catalyst showed highcatalytic activity towards the oxidation of HMF, affording 100% of HMF conversion at 130 8C after 12 hunder atmospheric oxygen pressure. 2,5-Furandicarboxylic acid (FDCA) and 2,5-diformylfuran (DFF)were detected to be the major oxidation products.

Controlled synthesis and luminescence properties of doped NaLa(WO4)2 microstructures

Yunhua Han,Yan Wang,Shaohua Huang,Fan-Long Jin,Shili Gai,Na Niu,Liuzhen Wang,Piaoping Yang 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.34 No.-

In this work, well-defined NaLa(WO4)2microstructures were prepared by a facile hydrothermal processin the presence of oleylamine and oleic acid as a mixed surfactant. The phase, morphology, size andluminescence properties were well characterized by means of X-ray diffraction (XRD), scanning electronmicroscopy (SEM), transmission electron microscopy (TEM), photoluminescence (PL) spectra, and decaytime, respectively. The results reveal that the morphology and size of the as-synthesized samples can betuned by altering the reaction time and the amounts of oleic acid. A possible formation mechanism oftetragonal NaLa(WO4)2 is proposed on the basis of oleic acid amount-dependent experiments. Uponultraviolet (UV) excitation, NaLa(WO4)2:Eu3+ and NaLa(WO4)2:Tb3+ exhibit the characteristic downconversionemissions of Eu3+ and Tb3+. Yb3+/Er3+ and Yb3+/Tm3+ co-doped NaLa(WO4)2 samples showstrong green (Er3+, 4S3/2, 2H11/2!4I15/2) and blue (Tm3+, 1G4!3H6) up-conversion emission under980 nm laser diode excitation. Upconversion emission mechanisms of NaLa(WO4)2:Ln (Ln = Yb/Er, Yb/Tm) are also presented based on the emission spectra and the plot of luminescence intensity to pumppower. It should be noted that the intensity of the upconversion emissions can be dramatically enhancedcompared with sodium free tungstates, which can be attributed to the charge compensation and meansthe introduction of Na+ ions in WO42 causes less distortion in the crystal structure.

Risk of Trastuzumab-Related Cardiotoxicity in Early Breast Cancer Patients: A Prospective Observational Study

Jian Xue,Zefei Jiang,Fan Qi,Shuanghong Lv,Shaohua Zhang,Tao Wang,Xiaozhong Zhang 한국유방암학회 2014 Journal of breast cancer Vol.17 No.4

Purpose: In the present study, we investigated the incidence ofcardiotoxicity within 5 years of trastuzumab treatment and evaluatedpotential risk factors in clinical practice. Methods: The studycohort included 415 patients diagnosed with early breast cancer(EBC). Cardiotoxicity incidence was evaluated in patients receivingtrastuzumab and those who did not. Multivariate Cox proportionalhazards regression models were used to estimate hazardratios and 95% confidence intervals of potential risk factorsfor trastuzumab-related cardiotoxicity after appropriate adjustments. Results: Incidence of cardiotoxicity in patients treatedwith trastuzumab was significantly higher than that in controls(23.7% vs. 10.8%, p<0.001). This result was adjusted for factorsthat might increase the risk of cardiotoxicity, such as historyof coronary artery diseases or the use of anthracyclines for morethan four cycles. Conclusion: Our findings indicated that treatmentwith trastuzumab was strongly associated with cardiotoxicityin EBC patients.

Sex Comb on Midleg Like-2 Accelerates Hepatocellular Carcinoma Cell Proliferation and Metastasis by Activating Wnt/β-Catenin/EMT Signaling

Lei Du,Lina Wang,Hong Yang,Jianping Duan,Jianming Lai,Wei Wu,Shaohua Fan,Xiaoli Zhi 연세대학교의과대학 2021 Yonsei medical journal Vol.62 No.12

Purpose: The purpose of this study was to investigate the influences of sex comb on midleg like-2 (SCML2) on hepatocellular carcinoma (HCC) and potentially related mechanisms. Materials and Methods: SCML2 expression in tumor tissues and cells was analyzed using the TCGA database and/or qRT-PCR. The proliferation of HCC cells was detected by CCK-8, colony formation, and EdU assays. The migration and invasion of HCC cells were detected by transwell and wound healing assays. Apoptosis of HCC cells was determined by flow cytometry. Additionally, qRT-PCR and Western blot were used to detect the expression of SCML2 and Wnt/β-catenin/epithelial–mesenchymal transition (EMT) signaling. A xenograft model in mice was established to verify the in vitro findings. Results: We found that SCML2 was highly expressed in HCC tissues and cells and that high expression of SCML2 was correlated with poor prognosis in HCC patients. SCML2 overexpression promoted proliferation, invasion, and migration and repressed apoptosis of HCC cells. The reverse results were obtained in SCML2-silenced cells. Further, we found that SCML2 activated the Wnt/β-catenin/EMT pathway. SCML2 silencing reduced the protein levels of Wnt3a, β-catenin, N-cadherin, Vimentin, and Snail and enhanced E-cadherin protein expression both in vivo and in vitro. Conclusion: SCML2 silencing inhibits the proliferation, migration, and invasion of HCC cells by regulating the Wnt/β-catenin/EMT pathway.

Pd–Fe bimetallic nanoparticles anchored on N‑doped carbon‑modified graphene for efficient catalytic organic reactions

Yue Zhang,Jie Huang,Zixuan Dong,Yu Zhan,Jiangbo Xi,Jian Xiao,Shaohua Huang,Fan Tian 한국탄소학회 2023 Carbon Letters Vol.33 No.1

A promising approach to enhance catalytic performance of supported heterogeneous nano-metal catalysts is to uniformly disperse active nanoparticles on the support. In this work, N-doped carbon-modified graphene (G@NC) nanosheet is designed and prepared to anchor Pd–Fe bimetallic nanoparticles (Pd–Fe/G@NC). The N-doped carbon modification on graphene surface could construct a sandwich-like structure (G@NC), which not only prevented the re-stacking of graphene nanosheets but also provided confined space for stable anchoring of bimetallic Pd–Fe nanoparticles. Benefitted from the unique structural property and synergetic effect of metal Pd and Fe species, the as-obtained Pd–Fe/G@NC composite displays excellent catalytic activity toward 4-nitrophenol reduction reaction with a turnover frequency of 613.2 min? 1, which is far superior to that of the mono-metal counterparts (Fe/G@NC and Pd/G@NC). More importantly, Pd–Fe/G@NC catalyst also exhibits favorable catalytic performance in the reduction of other nitroaromatic compounds (nitrobenzene, 4-nitrotoluene, 4-chloronitrobenzene, and so on). In addition, Pd–Fe/G@NC can catalyze the oxidation of furfuraldehyde to furoic acid with a high yield of 88.64%. This work provides a new guide for rationally designing and developing advanced supported heterogeneous bimetallic catalyst.