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      • SCOPUSKCI등재
      • KCI등재

        Impact of a Dust Storm on Characteristics of Particle Matter (PM) in Guangzhou, China

        Qi Fan,Chong Shen,Xuemei Wang,Yuan Li,Wei Huang,Guixiong Liang,Shaoyi Wang,Zhuoer Huang 한국기상학회 2013 Asia-Pacific Journal of Atmospheric Sciences Vol.49 No.1

        A strong dust-storm (23-25 April, 2009) occurred in the provinces of Inner Mongolia, Gansu, and Shanxi, North China. Cities along the storm path (from north to south: Xi’ning, Lanzhou,Chengdu, Changsha, and Guangzhou) all experienced a sharp increase in particle matter (PM10) concentration. This is the first case that an Asian dust storm hit Guangzhou in Southern China. The impacts of dust storm on the characteristics of PM were investigated using samples collected in Guangzhou during 27-29 April, 2009. In addition, the mass concentration and chemical composition during a normal non-dust period (12-14 May, 2009) were compared with those in dust period. The results show that the concentration of PM10during the dust episode (0.231 mg m−3) was twice higher than that in the non-dust episode (0.103 mg m−3). Chemical analysis showed that concentrations of metal elements, enrichment factors of metal elements, and soluble ions during the dust episode were very different from those of non-dust. The total concentration of metal elements content in PM10 was 53.5 μg m−3 in the dust episode, which is about two times higher than that in non-dust episode (28.5 μgm−3). Increases in concentrations of Na, Ti, Zn, Cu, and Cr ranged from zero to 100% during the dust episode. However, the enrichment factors in non-dust episode were higher than that in dust-storm period,indicating that the above five chemicals originated mainly from local sources in Guangzhou. The concentrations of K, Mg, Al, Fe, Mn, V,and Co increased by over 100% in the dust episode, indicating their origins of remote sources. In the dust period, some water-soluble ions increased in PM10, but the main components in PM10 were SO42−,NO3− and NH4+. At last, we assessed the sources of dusts by analyzing synoptic situation and back trajectories of air mass in Guangzhou, and demonstrated that the main source of the dust storm was from Mongolia.

      • SCIESCOPUSKCI등재

        Multigene Phylogeny and Morphology of Ophiocordyceps alboperitheciata sp. nov., A New Entomopathogenic Fungus Attacking Lepidopteran Larva from Yunnan, China

        ( Qi Fan ),( Yuan-bing Wang ),( Guo-dong Zhang ),( De-xiang Tang ),( Hong Yu ) 한국균학회 2021 Mycobiology Vol.49 No.2

        A new fungus, Ophiocordyceps alboperitheciata, parasitic on the larva of Noctuidae (Lepidoptera) was identified from a survey of entomopathogenic fungi in Kunming Wild Duck Forest Park, Yunnan Province, China. It can be primarily distinguished from relatives by its longer fertile parts, sterile tips, superficial perithecia, narrower asci, and smaller septa of ascospores. As revealed from phylogenetic analyses inferred from nrSSU, nrLSU, tef-1α, rpb1, and rpb2 sequence data, O. alboperitheciata belongs to the Hirsutella citriformis clade in the genus Ophiocordyceps of Ophiocordycipitaceae, and forms a separated clade from other related species. The uniqueness of the taxon is significantly evidenced by both molecular phylogeny and morphology. Furthermore, the interspecific relationships in the H. citriformis clade are discussed.

      • Multi-path Routing Improved Protocol in AODV Based on Nodes Energy

        Xiaoxia Qi,Qijin Wang,Fan Jian 보안공학연구지원센터 2015 International Journal of Future Generation Communi Vol.8 No.1

        Aiming at energy-constrained of Ad Hoc network, this paper proposes a multi-path routing protocol (EM-AODV)I n AODV that based on nodes energy. EM-AODV designs methods of obtaining nodes energy by upgrading the route discovery and route maintenance process of AODV, calculates the path of comprehensive energy derived path priority by routes total hops and nodes energy to format the multi-path routing mechanism. The energy as the metric prerequisite during the routing process, by setting nodes energy bound and balancing nodes data forwarding to postpone network lifetime. Simulation results show that EM-AODV has lower average end-to-end delay, well improve the energy consumption.

      • KCI등재

        Primordial Drivers of Diabetes Heart Disease: Comprehensive Insights into Insulin Resistance

        Yajie Fan,Zhipeng Yan,Tingting Li,Aolin Li,Xinbiao Fan,Zhongwen Qi,Junping Zhang 대한당뇨병학회 2024 Diabetes and Metabolism Journal Vol.48 No.1

        Insulin resistance has been regarded as a hallmark of diabetes heart disease (DHD). Numerous studies have shown that insulin resistance can affect blood circulation and myocardium, which indirectly cause cardiac hypertrophy and ventricular remodeling, participating in the pathogenesis of DHD. Meanwhile, hyperinsulinemia, hyperglycemia, and hyperlipidemia associated with insulin resistance can directly impair the metabolism and function of the heart. Targeting insulin resistance is a potential therapeutic strategy for the prevention of DHD. Currently, the role of insulin resistance in the pathogenic development of DHD is still under active research, as the pathological roles involved are complex and not yet fully understood, and the related therapeutic approaches are not well developed. In this review, we describe insulin resistance and add recent advances in the major pathological and physiological changes and underlying mechanisms by which insulin resistance leads to myocardial remodeling and dysfunction in the diabetic heart, including exosomal dysfunction, ferroptosis, and epigenetic factors. In addition, we discuss potential therapeutic approaches to improve insulin resistance and accelerate the development of cardiovascular protection drugs.

      • KCI등재

        Geft is dispensable for the development of the second heart field

        ( Xiong Wei Fan ),( Ning Hou ),( Kai Ji Fan ),( Jia Jia Yuan ),( Xiao Yang Mo ),( Yun Deng ),( Yong Qi Wan ),( Yan Teng ),( Xiao Yang ),( Xius Han Wu ) 생화학분자생물학회 (구 한국생화학분자생물학회) 2012 BMB Reports Vol.45 No.3

        Geft is a guanine nucleotide exchange factor, which can specifically activate Rho family of small GTPase by catalyzing the exchange of bound GDP for GTP. Geft is highly expressed in the excitable tissue as heart and skeletal muscle and plays important roles in many cellular processes, such as cell proliferation, migration, and cell fate decision. However, the in vivo role of Geft remains unknown. Here, we generated a Geft conditional knockout mouse by flanking exons 5-17 of Geft with loxP sites. Cre-mediated deletion of the Geft gene in heart using Mef2c-Cre transgenic mice resulted in a dramatic decrease of Geft expression. Geft knockout mice develop normally and exhibit no discernable phenotype, suggesting Geft is dispensable for the development of the second heart field in mouse. The Geft conditional knockout mouse will be a valuable genetic tool for uncovering the in vivo roles of Geft during development and in adult homeostasis. (BMB reports 2012; 45(3): 153-158)

      • KCI등재

        Water Dispersible Graphene Sheets Produced from Unassembled Graphene–Polyaniline Nanohybrids

        Qi Li,Denian Li,Lijie Dong,Fan Sun,Jing Huang,Haian Xie,Chuanxi Xiong 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2015 NANO Vol.10 No.1

        We present an effcient process for producing water dispersible graphene sheets from unassembled graphene–polyaniline nanohybrids. The result of atomic force microscopy reveals that over 80% of thus-prepared graphitic sheets are single layers with typical thickness of approximately 0.8 nm. The proportion of modifying molecules in the product is found to be as low as 3.0 wt.%, as determined by elemental analysis. Along with its fascinating water dispersibility and remarkably high electrical conductivity, such material is anticipated to be very promising for use in graphene-based nanoelectronics and high-performance composites.

      • KCI등재
      • KCI등재

        Effectiveness and safety of acupuncture for angina pectoris: An overview of systematic reviews

        Qi Wen-Chuan,Fu Hong-Juan,Sun Rui-Rui,Li Xiang,Cai Ding-Jun,Wang Chao,Liang Fan-Rong 한국한의학연구원 2022 Integrative Medicine Research Vol.11 No.3

        Background: The number of systematic reviews or meta-analyses (SRs/MAs) on the effectiveness of acupuncture for angina pectoris (AP) is increasing. Due to the inconsistent conclusions and unknown quality of these SRs/MAs, this overview aimed to systematically evaluate and synthesize the existing SRs/MAs, attempting to provide more reliable evidence for the effectiveness and safety of acupuncture in the treatment of AP. Methods: SRs/MAs were searched via eight databases from inception to March 14, 2022. The risk of bias was evaluated using the Risk of Bias in Systematic reviews (ROBIS) tool. The quality of the methodology, reporting, and evidence were assessed by the Assess Systematic Reviews 2 (AMSTAR-2), the Preferred Reporting Item for Systematic Review and Meta-analysis for Acupuncture (PRISMA-A), and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system, respectively. Results: Sixteen SRs/MAs were included and fifteen SRs/MAs were considered being of critically low quality according to AMSTAR-2. Only three SRs/MAs were rated at low risk of bias. No study reported all the items listed in the PRISMA-A checklist. No high-quality evidence with GRADE assessment was found. With the low-quality evidence, acupuncture combined with other interventions was superior to monotherapy (medications or Chinese medicine) in the angina symptom and electrocardiogram recovery. No adverse effects owing to acupuncture were reported. Conclusions: Owing to the lack of high-quality evidence provided by the current SRs/MAs, the effective-ness of acupuncture for AP still warrants further proof. Further researches with more critical design and methodology are needed for providing more convincing evidence. Background: The number of systematic reviews or meta-analyses (SRs/MAs) on the effectiveness of acupuncture for angina pectoris (AP) is increasing. Due to the inconsistent conclusions and unknown quality of these SRs/MAs, this overview aimed to systematically evaluate and synthesize the existing SRs/MAs, attempting to provide more reliable evidence for the effectiveness and safety of acupuncture in the treatment of AP. Methods: SRs/MAs were searched via eight databases from inception to March 14, 2022. The risk of bias was evaluated using the Risk of Bias in Systematic reviews (ROBIS) tool. The quality of the methodology, reporting, and evidence were assessed by the Assess Systematic Reviews 2 (AMSTAR-2), the Preferred Reporting Item for Systematic Review and Meta-analysis for Acupuncture (PRISMA-A), and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system, respectively. Results: Sixteen SRs/MAs were included and fifteen SRs/MAs were considered being of critically low quality according to AMSTAR-2. Only three SRs/MAs were rated at low risk of bias. No study reported all the items listed in the PRISMA-A checklist. No high-quality evidence with GRADE assessment was found. With the low-quality evidence, acupuncture combined with other interventions was superior to monotherapy (medications or Chinese medicine) in the angina symptom and electrocardiogram recovery. No adverse effects owing to acupuncture were reported. Conclusions: Owing to the lack of high-quality evidence provided by the current SRs/MAs, the effective-ness of acupuncture for AP still warrants further proof. Further researches with more critical design and methodology are needed for providing more convincing evidence.

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