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      • 죽염섭취가 혈압 및 전해질에 미치는 영향

        방준호,박병윤,김동석 한국위생과학회 2002 한국위생과학회지 Vol.8 No.2

        The safety of bamboo salt on human body was evaluated by a clinical study intended for 13 volunteers, who took 10 or 15 grams of bamboo salt daily for 8 weeks in addition to the regular dietary salt intake. Blood pressure and serum electrolytes(Na, K, Cl, Ca, Pi) were investigated. No significant changes of blood pressure were observed in 5 volunteers who took 10 grams of bamboo salt. The systolic and diastolic blood pressures measured before and after taking bamboo salt were at range of 115~140 mmHg and 75~101 mmHg, 118~144 mmHg and 75~104mmHg respectively. Blood pressures observed in 8 volunteers, who took 15 grams of bamboo salt, were also not significantly changed. The systolic and diastolic blood pressures of them were at range of 106~132 mmHg and 65~88 mmHg, 114~124 mmHg and 73~81mmHg respectively. The changes of Na, K, Cl, and Pi in blood serum were not also observed.

      • KCI등재

        3D-CT를 이용한 골격성 III급 개방교합자의 악교정 수술 전, 후 설골 및 상기도의 변화

        이윤섭,백형선,이기준,유형석 대한치과교정학회 2009 대한치과교정학회지 Vol.39 No.2

        본 연구는 골격성 III급 개방교합자의 악교정 수술 전, 후 설골과 상기도의 변화를 3D-CT를 이용하여 관찰하고 이를 정상교합자와 비교하기 위하여 시행하였다. 전치부 개방교합을 동반한 골격성 III급 부정교합으로 진단되어 악교정 수술을 받은 환자 중 12명을 선정 후, 3D-CT를 통해 설골과 상기도의 3차원 입체영상을 분석하여, 악교정 수술 전, 후의 설골의 위치 변화 및 상기도의 부피 변화를 살펴보고, 이의 결과를 정상교합자 10명과 비교하였다. 설골은 골격성 III급 개방교합군에서 악교정 수술 전에 정상교합군의 설골에 비해 전방에 위치하고 있었고 악교정 수술 후 설골은 후, 상방으로 변화하였으나 유의성은 관찰되지 않았다. Hyoid plane과 mandibular plane이 이루는 각은 악교정 수술 전의 골격성 III급 개방교합군이 정상교합군보다 큰 값을 나타내었고, 악교정 수술 후에는 그 차이가 더욱 증가하였다. 골격성 III급 개방교합군의 상기도 부피는 정상교합자보다 작으며 이는, 악교정수술 후에 더욱 감소하였다. 3차원 영상 분석 결과, 골격성 III급 개방교합자의 상기도는 정상교합자에 비해 좁으며, 하악골 후퇴술 이후 더욱 감소하기 때문에 이는 수술적 개선의 안정성에 영향을 줄 수 있음을 알 수 있었다. Objective: The purpose of this study was to investigate the structural changes of the hyoid bone and upper airway after orthognathic surgery for skeletal class III anterior open bite patients, and make comparisons with normal occlusion. Methods: Pre- and post-operative computed tomography (CT) examinations were performed on 12 skeletal class III anterior open bite patients who were treated with mandibular setback osteotomy. Using the V-works 4.0 program, 3-dimensional images of the total skull, mandible, hyoid bone, and upper airway were evaluated. Results: In the Class III openbite group, the hyoid bone were all positioned anteriorly, compared to the Normal group (p < 0.05). The angle between the hyoid plane and mandibular plane in the Class III openbite group before surgery was greater than in the Normal group (p < 0.05), and the difference increased after surgery (p < 0.01). In the Class III openbite group, the volume of the upper airway decreased after surgery (p < 0.001) and the volume of the upper airway was smaller than the Normal group before and after surgery (p < 0.001). Conclusions: The narrow upper airway space in skeletal Class III openbite patients decreased after mandibular setback osteotomy. This may affect the post-surgical stability.

      • 우유와 두유를 혼합한 이유보충음료의 개발

        손경희,윤선,이민준,김순영,김용태,장동훈,강석필 연세대학교 생활과학연구소 2001 生活科學論集 Vol.10 No.1

        The purpose of this study is to develop an infant supplement composed of cow and soy milk which has acceptable taste and digestability and meets nutritional needs of the infants. Even though soy milk is and excellent source of protein for infants who are allergic to dairy products, its protein quality is still lower than that of regular milk. Therefore in the present study the development of sow-soy milk infant formula was attempted. To make the formula equal amount of cow and soy milk were mixed and supplemented with vitamins and minerals to meet the nutritional standards of breast milk, CODEX and recommended dietary allowances for Korean infants. In animal experimental study, the weight gain rate of weaning rats was highest in the order of 100% milk, cow-soy milk, control, soy milk, commercial soy infant milk group. Feed efficiency ratio(FER) were not significantly different among control, 100% milk and cow-soy milk groups. However, commercialized soy infant milk group showed significantly lower FER than other groups. When the cow-soy milk formula was fed to infant in the age of 5 month to 25 months, it did not show any unsatisfactory results in acceptability and bowel movements of the subjects. Since the cow-soy milk formula has not only all the nutrients for the physical growth of infants but also contains valuable physiological functional ingredients, it is expected to be a good choice of supplements for infants.

      • Structural and optical properties of chemically deposited CuInSe2 thin film in acidic medium.

        Yoon, Seog Joon,Lim, Iseul,Kang, Soon Hyung,Lee, Joong Kee,Lee, Haw Young,Lee, Wonjoo,Han, Sung-Hwan American Scientific Publishers 2012 Journal of Nanoscience and Nanotechnology Vol.12 No.5

        <P>Thin films of nanocrystalline CuInSe2 were prepared on glass substrates using chemical bath deposition in acidic medium at room temperature. Thickness of the chemically deposited CuInSe2 thin films was approximately 100 nm which composed of closely packed irregular grains of approximately 100-120 nm in diameter. X-ray diffraction pattern of CuInSe2 thin films showed nanocrystalline structure with (112) preferential orientation. The films exhibited faint black and direct band gap energy was 0.96 eV.</P>

      • SCOPUSKCI등재

        Retroperitoneal Pleomorphic Liposarcoma Mimicking Adrenal Cancer in F-18 FDG PET/CT

        Yoon, Min-Ki,Kim, Seog-Joon The Korea Society of Nuclear Medicine 2010 핵의학 분자영상 Vol.44 No.3

        Liposarcoma is the second most common type of soft tissue sarcoma, but pleomorphic liposarcoma is the least common subtype. We present the case of a 42-year-old man who had experienced intermittent left flank pain for a month. A large soft-tissue mass was detected by ultrasonography in a local clinic, and he was referred for further evaluation. Positron emission tomography/computed tomography (PET/CT) with F-18 fluoro-2-deoxy-D-glucose (F-18 FDG) showed intense uptake in the retroperitoneal mass, which mimicked an adrenal cancer. The patient underwent left radical nephroadrenalectomy, and the tumor was revealed to be a pleomorphic liposarcoma upon pathological examination. When there is a large retroperitoneal mass with intense F-18 FDG activity, the possibility of a pleomorphic liposarcoma should be considered.

      • SCOPUSSCIEKCI등재

        Stability of bimaxillary surgery involving intraoral vertical ramus osteotomy with or without presurgical miniscrew-assisted rapid palatal expansion in adult patients with skeletal Class Ⅲ malocclusion

        Yoon-Soo Ahn,Sung-Hwan Choi,Kee-Joon Lee,Young-Soo Jung,Hyoung-Seon Baik,Hyung-Seog Yu 대한치과교정학회 2020 대한치과교정학회지 Vol.50 No.5

        Objective: The aim of this study was to evaluate the stability of bimaxillary surgery involving bilateral intraoral vertical ramus osteotomy performed with or without presurgical miniscrew-assisted rapid palatal expansion (MARPE) in adult patients with skeletal Class Ⅲ malocclusion. Methods: A total of 40 adult patients with skeletal Class Ⅲ malocclusion were retrospectively divided into two groups (n = 20 each) according to the use of MARPE for the correction of transverse maxillomandibular discrepancy during presurgical orthodontic treatment. Serial lateral cephalograms and dental casts were analyzed until 6 months after surgery. Results: Before presurgical orthodontic treatment, there was no significant differences in terms of sex and age between groups. However, the difference of approximately 3.1 mm in the maxillomandibular intermolar width was statistically significant (p < 0.001). Two days after surgery, the mandible had moved backward and upward without any significant intergroup difference. Six months after surgery, the maxillary intercanine (2.7 ± 2.1 mm), interpremolar (3.6 ± 2.4 mm), and intermolar (2.0 ± 1.3 mm) arch widths were significantly increased (p < 0.001) relative to the values before presurgical orthodontic treatment in the MARPE group; these widths were maintained or decreased in the control group. However, there was no significant difference in surgical changes and the postsurgical stability between the two groups. No significant correlations existed between the amount of maxillary expansion and postsurgical mandibular movement. Conclusions: MARPE is useful for stable and nonsurgical expansion of the maxilla in adult patients with skeletal Class Ⅲ malocclusion who are scheduled for bimaxillary surgery.

      • KCI등재

        Immune checkpoint inhibitors in patients with pretreated Hodgkin’s lymphoma: a Korean single-center, retrospective study

        Joon Young Hur,Sang Eun Yoon,Seok Jin Kim,Won Seog Kim 대한혈액학회 2020 Blood Research Vol.55 No.2

        BackgroundImmune checkpoint inhibitors have demonstrated efficacy in the treatment of classical Hodgkin’s lymphoma (cHL). We analyzed the efficacy and safety of pembrolizumab or nivolumab in patients with pretreated cHL. MethodsClinical data from the cancer chemotherapy registry of Samsung Medical Center were retrospectively analyzed to study patients with cHL treated with pembrolizumab or nivo-lumab between Oct 2015 and Dec 2018. ResultsOf the 20 patients, seven (35%) were enrolled in the study after a relapse following autolo-gous hematopoietic stem cell transplantation (ASCT) and 12 (60%) after a relapse follow-ing receipt of brentuximab vedotin (BV). Sixteen (80%) patients received pembrolizumab, and four (20%) patients received nivolumab. The complete remission rate was 45% (9/20), and 30% (6/20) of patients achieved partial remission, for an overall response rate (RR) of 75% [15/20; 95% confidence interval (CI), 34.7‒93.3]. With a median follow-up dura-tion of 14 months, the median PFS was 18 months (95% CI, 2.4‒33.5 mo), and the median OS was 36 months [95% CI, 36-not applicable (NA) mo]. Pembrolizumab and nivolumab were generally well tolerated.ConclusionIn this study, pembrolizumab and nivolumab both demonstrated clinical efficacy and tol-erability in patients with cHL who failed previous chemotherapy or ASCT.

      • KCI등재후보

        위석의 내시경적 레이저 치료 2예 : A report of two cases

        윤종일,안석주,한준열,백남종,임계순 대한내과학회 1990 대한내과학회지 Vol.38 No.4

        Gastric bezoars are foreign bodies or concretions composed of indigested or partially digested food or hair found in the stomach of men or animals, which occur relatively often and are potentially hazardous. They can cause mucosal ulceration or wall perforation, gastritis, gastric outlet obstruction, massive gastrointestinal bleeding, megaloblastic anemia, protein-losing enteropathy and ileus. So their removal is generally necessary to correct or prevent these complications. Within the last 20 years, the treatment modality of gastric bezoars had changed from surgical to nonsurgical intervention. However, the nonsurgical techniques, such as ingestion of enzymes, nasogastric suction and various endoscopic methods, have been tried with varying degrees of success. Endoscopic methods for removing bezoars using forceps or snares and a pulsating jet of water have previously been reported. We employed endoscopic Nd: YAG laser photoablation to reduce the size of huge gastric bezoars in two cases. The reduced bezoars were then disrupted successfully using a polypectomy snare. We think endoscopic laser photoablation could be one of the treatment method in the case of huge gastric bezoars.

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