한국 남서해안 영광군 염산 조간대의 퇴적상과 퇴적작용

김여상,이덕성 공주대학교 과학교육연구소 2003 과학교육연구 Vol.34 No.-

본 연구의 목적은 한국 서해안의 영광군 염산 해안에 발달한 조간대에서의 퇴적상과 퇴적작용을 조사하는 것이다. 이 조간대로부터 48개의 표층퇴적물 시료가 채취되었고 퇴적구조물들이 조사되었다. 연구지역의 조간대는 조직과 퇴적구조를 기준으로 니퇴적상, 사질실트퇴적상, 모래퇴적상으로 구분된다. 니퇴적상은 고조선 부근에 분포하며, 매우 불량한 분급과 세립질의 말미부분이 매우 우세한 실트와 이토로 이루어졌다. 퇴적구조는 균질층리, 렌즈상 층리, 얇은 교호층리가 관찰되고 있으나 생물교란작용을 많이 받고 있다. 사질실트 퇴적상은 모래퇴적상과 니질퇴적상 사이의 넓은 지역에 분포하고, 퇴적물은 분급이 매우 불량한 사질실트로 구성되어 있고, 퇴적구조는 얇은 교호층리와 렌즈상 층리가 나타난다. 생물퇴적구조가 풍부하다. 모래퇴적상은 저조선 부근에 분포하며, 분급이 양호하고 조립질 말미부분이 우세한 세립모래로 이루어져 있다. 퇴적구조는 고연흔, 대연흔, 사층리 그리고 평형모래엽리가 있다. 염산조간대의 표층퇴적물 분포의 계절변화는 뚜렷하여 겨울에는 모래가 집적되고, 여름에는 모래퇴적물 위에 니(mud)가 두께 50㎝ 이하로 퇴적된다. 퇴적물 분포의 계절적 변화는 계쩔에 따른 바람의 강도에 의해 야기되는 것으로 판단된다. This research aims to examine the intertidal facies and the intertidal sedimentation in YeomsanCoast at Yeonggwang-gun in the southwestern coast of Korea.. 48 surface sediment samples were taken from the intertidal flat. The intertidal flat is divided into three sedimentary facies based on textures and sedimentary structures ; mud facies, sandy silt facies, and sand facies. The mud facies occurs near the high tide level and consists of very poorly sorted and strongly fine skewed silt and mud. The major sedimentary structures are homogeneous bedding, lenticular bedding, and thinly interlayered bedding, but they are poorly preserved because of strong bioturbation. The sandy silt facies is developed on broad areas between sand facies and mud facies. The sediments are very poorly sorted sandy silt. It is characterized by thinly interlayered bedding and lenticular bedding. Biogenic sedimentary structures are abundant. The sand facies occurs near the low tide level and consists of well sorted and coarse skewed fine sand. The sedimentary structures consist of small ripples and megaripples, cross-bedding, and evenly laminated sand. The seasonal change of surface sediments at Yeomsan intertidal flat is distinctive. The sand is accumulated in winter while mud is accumulated in summer. The muddy sediments overlie the sand sediment and their thickness is than about 50 cm in summer. The seasonal change is thought to be caused by the strength of wave activity.

급성 대상포진 관련 통증과 포진 후신경통의 임상상과 신경 차단술

성덕현,김상용,이강우,이일수,여운철 大韓再活醫學會 2000 Annals of Rehabilitation Medicine Vol.24 No.1

Electrical and Boron Diffusion Characteristics in the AS Preamorphized P+ Polysillicon Gate

Sang Jik Kwon,Yeo Hwan Kim,Jong Duk Lee 대한전자공학회 1994 대한전자공학회 학술대회 Vol.1994 No.1

Ginsenoside fractions regulate the action of monocytes and their differentiation into dendritic cells

Yeo Jin Lee,Young Min Son,Min Jeong Gu,Ki-Duk Song,Sung-Moo Park,Hyo Jin Song,Jae Sung Kang,Jong Soo Woo,Jee Hyung Jung,Deok-Chun Yang,Seung Hyun Han,Cheol-Heui Yun 고려인삼학회 2015 Journal of Ginseng Research Vol.39 No.3

Background: Panax ginseng (i.e., ginseng) root is extensively used in traditional oriental medicine. It is a modern pharmaceutical reagent for preventing various human diseases such as cancer. Ginsenosidesdthe major active components of ginsengdexhibit immunomodulatory effects. However, the mechanism and function underlying such effects are not fully elucidated, especially in human monocytes and dendritic cells (DCs). Methods: We investigated the immunomodulatory effect of ginsenosides from Panax ginseng root on CD14⁺ monocytes purified from human adult peripheral blood mononuclear cells (PBMCs) and on their differentiation into DCs that affect CD4⁺ T cell activity. Results: After treatment with ginsenoside fractions, monocyte levels of tumor necrosis factor (TNF)-a, interleukin (IL)-6, and IL-10 increased through phosphorylation of extracellular signal-regulated kinase (ERK)1/2 and c-Jun N-terminal kinase (JNK), but not p38 mitogen-activated protein kinase (MAPK). After treatment with ginsenoside fractions, TNF-α production and phosphorylation of ERK1/2 and JNK decreased in lipopolysaccharide (LPS)-sensitized monocytes.We confirmed that DCs derived from CD14⁺ monocytes in the presence of ginsenoside fractions (Gin-DCs) contained decreased levels of the costimulatory molecules CD80 and CD86. The expression of these costimulatory molecules decreased in LPS-treated DCs exposed to ginsenoside fractions, compared to their expression in LPS-treated DCs in the absence of ginsenoside fractions. Furthermore, LPS-treated Gin-DCs could not induce proliferation and interferon gamma (IFN-γ) production by CD4⁺ T cells with the coculture of Gin-DCs with CD4⁺ T cells. Conclusion: These results suggest that ginsenoside fractions from the ginseng root suppress cytokine production and maturation of LPS-treated DCs and downregulate CD4⁺ T cells.

Enhanced Production of Epothilones by Carbon Sources in sorangium cellulosum

( Sang Woo Park ),( Sue Hyung Choi ),( Yeo Joon Yoon ),( Dong Hyun Lee ),( Duk Joon Kim ),( Ji Heung Kim ),( Young Kwan Lee ),( Guang Jin Choi ),( Ick Tae Yeom ),( Sang Jun Sim ) 한국미생물생명공학회 2006 Journal of microbiology and biotechnology Vol.16 No.4

Fabrication of Sub-Half Micron PMOS Device

Yeo Hwan Kim,Sang Jik Jwon,KuK Jin Chun,Jong Duk Lee 대한전자공학회 1992 대한전자공학회 학술대회 Vol.1992 No.1

Ginsenoside fractions regulate the action of monocytes and their differentiation into dendritic cells

Yeo Jin Lee,Young Min Son,Min Jeong Gu,Ki-Duk Song,Sung-Moo Park,Hyo Jin Song,Jae Sung Kang,Jong Soo Woo,Jee Hyung Jung,Deok-Chun Yang,Seung Hyun Han,Cheol-Heui Yun 고려인삼학회 2015 Journal of Ginseng Research Vol.39 No.1

Background: Panax ginseng (i.e., ginseng) root is extensively used in traditional oriental medicine. It is a modern pharmaceutical reagent for preventing various human diseases such as cancer. Ginsenosidesd-the major active components of ginsengdexhibit immunomodulatory effects. However, the mechanism and function underlying such effects are not fully elucidated, especially in human monocytes and dendritic cells (DCs). Methods: We investigated the immunomodulatory effect of ginsenosides from Panax ginseng root on CD14⁺ monocytes purified from human adult peripheral blood mononuclear cells (PBMCs) and on their differentiation into DCs that affect CD4⁺ T cell activity. Results: After treatment with ginsenoside fractions, monocyte levels of tumor necrosis factor (TNF)-α, interleukin (IL)-6, and IL-10 increased through phosphorylation of extracellular signal-regulated kinase (ERK)1/2 and c-Jun N-terminal kinase (JNK), but not p38 mitogen-activated protein kinase (MAPK). After treatment with ginsenoside fractions, TNF-α production and phosphorylation of ERK1/2 and JNK decreased in lipopolysaccharide (LPS)-sensitized monocytes.We confirmed that DCs derived from CD14⁺ monocytes in the presence of ginsenoside fractions (Gin-DCs) contained decreased levels of the costimulatory molecules CD80 and CD86. The expression of these costimulatory molecules decreased in LPS-treated DCs exposed to ginsenoside fractions, compared to their expression in LPS-treated DCs in the absence of ginsenoside fractions. Furthermore, LPS-treated Gin-DCs could not induce proliferation and interferon gamma (IFN-γ) production by CD4⁺ T cells with the coculture of Gin-DCs with CD4⁺ T cells. Conclusion: These results suggest that ginsenoside fractions from the ginseng root suppress cytokine production and maturation of LPS-treated DCs and downregulate CD4⁺ T cells.

INFLUENCING FACTORS FOR SATISFACTION WITH LECTURES OF NON-DEGREE PROGRAMS: IMPLICATIONS FOR STRATEGIC MARKETING

Sung Hwan Yeo,Kyung Hoon Kim,Yeoung Duk Koo 글로벌지식마케팅경영학회 2015 Global Fashion Management Conference Vol.2015 No.06

Global depression has brought the Korean economy into the period of low growth. The notion of lifetime employment has long crumbled, while economic recession is gradually taking away quality jobs. Furthermore, the average lifespan for the population has neared 100, while baby-boomer retirement is swinging into high gear. The simultaneous inrush of social and economic problems is threatening our wellbeing. However, there has been insufficient amount of research conducted on the factors that influence the satisfaction with lectures in lifelong education designed to address the problems. If we look at the earlier studies, most of them are on the satisfaction with lectures in regular courses. Our society demands that jobs be created for retirees including the baby boomers and that quality jobs be provided for those who want to go back to work after they have withdrawn from previous employment. In this light, the current study aims to bring light on the causal relation between the influential factors and variables involved in the satisfaction of lectures of non-degree programs with a view to solving those problems, and suggests the need to draw up marketing strategy that uses it. Specifically, the purpose and method of this study are as follows. First, to develop variables to be used in this study through in-depth interviews with field staff in the industry and training staff. Second, to identify predisposing factors that influence the satisfaction with the lectures of non-degree programs. Third, to identify the variables mediating predisposing factors and satisfaction with lectures. Fourth, to propose marketing strategy for non-degree programs using the results of the study. As identified through this study, the influencing factors for satisfaction with lectures are physical environment, composition of contents, and instructor ability and attitude, while mediating variables are interaction and immersion in lectures. If these factors are reflected in education, a higher level of satisfaction with lectures will be ensured for business starting youths, retirees, and those who want to have some other job after withdrawing from their previous ones. Educational institutions will be able to use it in ensuring stabler recruiting of trainees and establish a more efficient guidance and marketing strategy. Reflecting the results of the study in education will contribute to heightening educational sustainability, social sustainability, and economic sustainability.

Identification of novel candidate genes implicated in odontogenic potential in the developing mouse tooth germ using transcriptome analysis

Shin Yeo-Kyeong,Cheon Seongmin,Kim Sung-Duk,Moon Jung-Sun,Kim Jae-Young,Kim Sun-Hun,박춘구,김민석 한국유전학회 2021 Genes & Genomics Vol.43 No.9

Background In tooth bioengineering for replacement therapy of missing teeth, the utilized cells must possess an inductive signal-forming ability to initiate odontogenesis. This ability is called odontogenic potential. In mice, the odontogenic potential signal is known to be translocated from the epithelium to the mesenchyme at the early bud stage in the developing molar tooth germ. However, the identity of the molecular constituents of this process remains unclear. Objective The purpose of this study is to determine the molecular identity of odontogenic potential and to provide a new perspective in the feld of tooth development research. Methods In this study, whole transcriptome profles of the mouse molar tooth germ epithelium and mesenchyme were investigated using the RNA sequencing (RNA-seq) technique. The analyzed transcriptomes corresponded to two developmental stages, embryonic day 11.5 (E11.5) and 14.5 (E14.5), which represent the odontogenic potential shifts. Results We identifed diferentially expressed genes (DEGs), which were specifcally overexpressed in both the E11.5 epithelium and E14.5 mesenchyme, but not expressed in their respective counterparts. Of the 55 DEGs identifed, the top three most expressed transcription factor genes (transcription factor AP-2 beta isoform 3 [TFAP2B], developing brain homeobox protein 2 [DBX2], and insulin gene enhancer protein ISL-1 [ISL1]) and three tooth development-related genes (transcription factor HES-5 [HES5], platelet-derived growth factor D precursor [PDGFD], semaphrin-3 A precursor [SEMA3A]) were selected and validated by quantitative RT-PCR. Using immunofuorescence staining, the TFAP2B protein expression was found to be localized only at the E11.5 epithelium and E14.5 mesenchyme. Conclusions Thus, our empirical fndings in the present study may provide a new perspective into the characterization of the molecules responsible for the odontogenic potential and may have an implication in the cell-based whole tooth regeneration strategy.

Protective effects of Tat-NQO1 against oxidative stress-induced HT-22 cell damage, and ischemic injury in animals

( Hyo Sang Jo ),( Duk-soo Kim ),( Eun Hee Ahn ),( Dae Won Kim ),( Min Jea Shin ),( Su Bin Cho ),( Jung Hwan Park ),( Chi Hern Lee ),( Eun Ji Yeo ),( Yeon Joo Choi ),( Hyeon Ji Yeo ),( Christine Seok Y 생화학분자생물학회(구 한국생화학분자생물학회) 2016 BMB Reports Vol.49 No.11

Oxidative stress is closely associated with various diseases and is considered to be a major factor in ischemia. NAD(P)H: quinone oxidoreductase 1 (NQO1) protein is a known antioxidant protein that plays a protective role in various cells against oxidative stress. We therefore investigated the effects of cell permeable Tat-NQO1 protein on hippocampal HT-22 cells, and in an animal ischemia model. The Tat-NQO1 protein transduced into HT-22 cells, and significantly inhibited against hydrogen peroxide (H₂O₂)-induced cell death and cellular toxicities. Tat-NQO1 protein inhibited the Akt and mitogen activated protein kinases (MAPK) activation as well as caspase-3 expression levels, in H₂O₂ exposed HT-22 cells. Moreover, Tat-NQO1 protein transduced into the CA1 region of the hippocampus of the animal brain and drastically protected against ischemic injury. Our results indicate that Tat-NQO1 protein exerts protection against neuronal cell death induced by oxidative stress, suggesting that Tat-NQO1 protein may potentially provide a therapeutic agent for neuronal diseases. [BMB Reports 2016; 49(11): 617-622]