Phase-space Analysis in the Group and Cluster Environment: Time Since Infall and Tidal Mass Loss

Jinsu Rhee,Rory Smith,Hoseung Choi,Sukyoung K. Yi,Yara Jaffé,Graeme Candlish,Ruben Sánchez-Jánssen 한국천문학회 2017 天文學會報 Vol.42 No.2

Is Sacral Extension a Risk Factor for Early Proximal Junctional Kyphosis in Adult Spinal Deformity Surgery?

Sebastian Decker,Renaud Lafage,Christian Krettek,Robert Hart,Christopher Ames,Justin S. Smith,Douglas Burton,Eric Klineberg,Shay Bess,Frank J. Schwab,Virginie Lafage,International Spine Study Group 대한척추외과학회 2020 Asian Spine Journal Vol.14 No.2

Study Design: Retrospective cohort study. Purpose: To investigate the role of sacral extension (SE) for the development of proximal junctional kyphosis (PJK) in adult spinal deformity (ASD) surgery. Overview of Literature: The development of PJK is multifactorial and different risk factors have been identified. Of these, there is some evidence that SE also affects the development of PJK, but data are insufficient. Methods: Using a combined database comprising two propensity-matched groups of fusions following ASD surgery, one with fixation to S1 or S1 and the ilium (SE) and one without SE but with a lower instrumented vertebra of L5 or higher (lumbar fixation, LF), PJK and the role of further parameters were analyzed. The propensity-matched variables included age, the upper-most instrumented vertebra (UIV), preoperative sagittal alignment, and the baseline to 1 year change of the sagittal alignment. Results: Propensity matching led to two groups of 89 patients each. The UIV, pelvic incidence minus lumbar lordosis, sagittal vertical axis, pelvic tilt, age, and body mass index were similar in both groups (p>0.05). The incidence of PJK at postoperative 1 year was similar for SE (30.3%) and LF (22.5%) groups (p=0.207). The PJK angle was comparable (p=0.963) with a change of −8.2° (SE) and −8.3° (LF) from the preoperative measures (p=0.954). A higher rate of PJK after SE (p=0.026) was found only in the subgroup of patients with UIV levels between T9 and T12. Conclusions: Instrumentation to the sacrum with or without iliac extension did not increase the overall risk of PJK. However, an increased risk for PJK was found after SE with UIV levels between T9 and T12.

First cosmological results using Type Ia supernovae from the Dark Energy Survey: measurement of the Hubble constant

Macaulay, E,Nichol, R C,Bacon, D,Brout, D,Davis, T M,Zhang, B,Bassett, B A,Scolnic, D,Mö,ller, A,D’Andrea, C B,Hinton, S R,Kessler, R,Kim, A G,Lasker, J,Lidman, C,Sako, M,Smith, M,Sullivan, M,Abbo Oxford University Press 2019 MONTHLY NOTICES- ROYAL ASTRONOMICAL SOCIETY Vol.486 No.2

<B>ABSTRACT</B><P>We present an improved measurement of the Hubble constant (H0) using the ‘inverse distance ladder’ method, which adds the information from 207 Type Ia supernovae (SNe Ia) from the Dark Energy Survey (DES) at redshift 0.018 &lt; z &lt; 0.85 to existing distance measurements of 122 low-redshift (z &lt; 0.07) SNe Ia (Low-z) and measurements of Baryon Acoustic Oscillations (BAOs). Whereas traditional measurements of H0 with SNe Ia use a distance ladder of parallax and Cepheid variable stars, the inverse distance ladder relies on absolute distance measurements from the BAOs to calibrate the intrinsic magnitude of the SNe Ia. We find H0 = 67.8 ± 1.3 km s−1 Mpc−1 (statistical and systematic uncertainties, 68 per cent confidence). Our measurement makes minimal assumptions about the underlying cosmological model, and our analysis was blinded to reduce confirmation bias. We examine possible systematic uncertainties and all are below the statistical uncertainties. Our H0 value is consistent with estimates derived from the Cosmic Microwave Background assuming a ΛCDM universe.</P>

Adipogenic gene expression and fatty acid composition in subcutaneous adipose tissue depots of Angus steers between 9 and 16 months of age1

Smith, S. B.,Go, G. W.,Johnson, B. J.,Chung, K. Y.,Choi, S. H.,Sawyer, J. E.,Silvey, D.T.,Gilmore, L. A.,Ghahramany, G.,Kim, K. H. Oxford University Press 2012 Journal of animal science Vol.90 No.8

<P>We have demonstrated that among carcass adipose tissue depots, brisket subcutaneous adipose tissue contains the greatest concentration of MUFA and lowest concentration of SFA. Therefore, we hypothesized that brisket subcutaneous adipose tissue depots would exhibit greater adipogenic gene expression over time than other major subcutaneous adipose tissue depots. Four Angus steers, each at 9, 12, 14, and 16 mo of age, were harvested and fresh subcutaneous adipose tissue samples were collected from over the brisket, chuck, rib, loin, sirloin, round, flank, and plate. Relative gene expression for C/EBPβ, PPARγ, carnitine palmitoyltransferase-1 beta (CPT-1β), stearoyl-coenzyme A desaturase (SCD), AMP-activated protein kinase alpha (AMPKα), and G-coupled protein receptor 43 (GPR43) was analyzed by quantitative real-time PCR. Expression of C/EBPβ, PPARγ, and CPT-1β was greatest at 12 to 14 mo of age (all P < 0.0001) and declined to very low abundance by 16 mo of age in all depots. Expression of PPARγ and CPT-1β was greater (P < 0.03) in flank, rib, and sirloin subcutaneous adipose tissues than in brisket and round adipose tissues. The expression of the SCD gene did not differ among the 4 age groups (P = 0.95). The palmitoleic:stearic acid ratio (an estimate of SCD activity) was greater (P < 0.001) in the subcutaneous adipose tissues from brisket, plate, and round than in the loin, rib, and sirloin. Conversely, subcutaneous adipose tissue from the loin, rib, and sirloin had greater (P < 0.001) SCD gene expression than the brisket, plate, and round. In general, subcutaneous adipose tissues with the highest concentration of MUFA and least SFA consistently exhibited the least SCD gene expression and adipogenic gene expression. We conclude that MUFA in the brisket and other depots with large SCD indices were deposited before 9 mo of age, during a time when the subcutaneous adipocytes were highly differentiated.</P>

Microbiological Quality of Alternative Water Sources in the Urban Environment

( J. P. S. Sidhu ),( W. Ahmed ),( L. Hodgers ),( K. Smith ),( S. Toze ) 한국물환경학회 2017 한국물환경학회·대한상하수도학회 공동 춘계학술발표회 Vol.2017 No.-

In Australia, decreasing rainfall, frequent drought and population growth in urban environments, along with an overall desire to achieve greater water sustainability, has increased the demand for alternative water sources such as stormwater, roof-harvested rainwater, and treated wastewater effluent. The potential public health risks associated with alternative water sources predominantly originate from the presence of enteric viruses, pathogenic bacteria, and protozoan parasites. Empirical data on the presence of pathogens is a prerequisite to accurately determine human health risks and the extent of treatment required prior to use for potable and nonpotable purposes. We have carried out a number of targeted studies on the microbiological quality of the roof-harvested rainwater, stormwater, and treated wastewater effluent in the Southeast Queensland (Australia). The main of aim these studies was to collect quantitative data on the presence of pathogens and make an assessment of the potential health risk associated with water reuse. A dedicated survey of the roof-harvested rainwater tanks in Brisbane has shown the presence of Campylobacter spp. (21%), Salmonella spp., (4%), and Giardia lamblia (13%). In addition, opportunistic pathogens Legionella spp. (99%) and Mycobacterium intracellulare (78%) were also detected\. The numbers of bacteria ranged up to 3.1 x 10⁶ PCR detectable units (pdu) L^-1 for Legionella spp., 9.6 X 10⁵ pdu L^-1 for P. aeruginosa, 6.8 X 10⁵ pdu L^-1 for M. intracellulare, 6.6 x 10⁵ pdu L^-1 for Acanthamoeba spp., 1.1 x 10⁵ pdu L^-1 for M. avium, and 9.8 X 10³ pdu L^-1 for L. pneumophila. The presence of potential opportunistic pathogens in tank water may present health risks if un-treated water is for potable and non-potable use in the house. Stormwater runoff from two urban catchments with different drainage area, impervious area, and land use, a potential source of pollution and population density was collected and analyzed for the presence of pathogens and fecal indicator bacteria. The mean FIB numbers in water samples collected after the storm event ranged from 10 ³ to 10⁴ L^-1 for E. coli and 10 ⁴ to 10⁵ L^-1 for Enterococcus spp. Salmonella enterica numbers varied between 10 to 2400 MPN L^-1. Human adenovirus (HAdV) numbers in the stormwater varied between 10 to 10³ pdu L^-1, human polyomavirus (HPyV) numbers varied between 1 to 10³ pdu L^-1. Torque teno virus (HTtV) numbers varied between 10 to 7.45 x 10³ pdu L^-1. Somatic coliphages (Microviridae) was also widely prevalent with numbers varying between 10 to 10³ pdu L^-1. The results of this study suggest that enteric virus and bacterial pathogens frequently occur in the stormwater runoff in significant numbers which could lead to increased human health risks. A quantitative survey HAdV, HPyV, HTtV and somatic coliphage (Microviridae) numbers in influent and effluent samples was carried out from three wastewater treatment plants (WWTP) employing an activated sludge process to produce secondary treated effluent in Brisbane. HPyV, HAdV, HTtV and Microviridae were consistently detected in the primary influent in high numbers (10⁵ to 10⁶ pdu L^-1) and secondary treated effluent (10² to 10³ pdu L^-1) across all three treatment plants. Under appropriate conditions, WWTPs with activated sludge process could be an effective treatment barrier with > 3 log10 removal of enteric. The results confirm the occurrence of enteric viruses in significant numbers in secondary treated effluent, tertiary treatment may be required prior to effluent reuse or discharged into the environmental to prevent exposure of people to health hazards.

Environmental Research by laser techniques at the Lund Institute of Technology

Smith,J.,sandsten,J.,Somesfalean,G.,Edner,H.,Saito,Y.,Svanberg,S.,Gustafsson,U.,Alnis,J.,Weibring,P. 慶熙大學校 레이저 工學硏究所 1999 레이저공학 Vol.10 No.-

Laser spectroscopy provides many possibility for advanced monitoring and diagnostics in the fields of environmental research. A broad range of applied laser spectroscopy is pursued at the Lund Institute of Technology and a brief survey of our recent work in laser environmental monitoring will be given with reference to published papers.

Spin-Torque Switching in Integrated ST-MRAM Arrays

J.M. Slaughter,N.D. Rizzo,F.B. Mancoff,R. Whig,J.J. Sun,K. Smith,K. Nagel,T. Andre,D. Houssameddine,S. Tehrani 한국자기학회 2010 한국자기학회 학술연구발표회 논문개요집 Vol.2010 No.12

European 1: A globally important clonal complex of Mycobacterium bovis

Smith, N.H.,Berg, S.,Dale, J.,Allen, A.,Rodriguez, S.,Romero, B.,Matos, F.,Ghebremichael, S.,Karoui, C.,Donati, C.,Machado, A.d.C.,Mucavele, C.,Kazwala, R.R.,Hilty, M.,Cadmus, S.,Ngandolo, B.N.R.,Habt Elsevier Science 2011 Infection, genetics and evolution Vol.11 No.6

We have identified a globally important clonal complex of Mycobacterium bovis by deletion analysis of over one thousand strains from over 30 countries. We initially show that over 99% of the strains of M. bovis, the cause of bovine tuberculosis, isolated from cattle in the Republic of Ireland and the UK are closely related and are members of a single clonal complex marked by the deletion of chromosomal region RDEu1 and we named this clonal complex European 1 (Eu1). Eu1 strains were present at less than 14% of French, Portuguese and Spanish isolates of M. bovis but are rare in other mainland European countries and Iran. However, strains of the Eu1 clonal complex were found at high frequency in former trading partners of the UK (USA, South Africa, New Zealand, Australia and Canada). The Americas, with the exception of Brazil, are dominated by the Eu1 clonal complex which was at high frequency in Argentina, Chile, Ecuador and Mexico as well as North America. Eu1 was rare or absent in the African countries surveyed except South Africa. A small sample of strains from Taiwan were non-Eu1 but, surprisingly, isolates from Korea and Kazakhstan were members of the Eu1 clonal complex. The simplest explanation for much of the current distribution of the Eu1 clonal complex is that it was spread in infected cattle, such as Herefords, from the UK to former trading partners, although there is evidence of secondary dispersion since. This is the first identification of a globally dispersed clonal complex M. bovis and indicates that much of the current global distribution of this important veterinary pathogen has resulted from relatively recent International trade in cattle.

The sensitivity of harassment to orbit: mass loss from early-type dwarfs in galaxy clusters

Smith, R.,Sá,nchez-Janssen, R.,Beasley, M. A.,Candlish, G. N.,Gibson, B. K.,Puzia, T. H.,Janz, J.,Knebe, A.,Aguerri, J. A. L.,Lisker, T.,Hensler, G.,Fellhauer, M.,Ferrarese, L.,Yi, S. K. Oxford University Press 2015 Monthly notices of the Royal Astronomical Society Vol.454 No.3

AMPKα, C/EBPβ, CPT1β, GPR43, PPARγ, and SCD Gene Expression in Single- and Co-cultured Bovine Satellite Cells and Intramuscular Preadipocytes Treated with Palmitic, Stearic, Oleic, and Linoleic Acid

S. H. Choi,박성권,B.J. Johnson,K.Y. Chung,C.W. Choi,김경훈,W.Y. Kim,S.B. Smith 아세아·태평양축산학회 2015 Animal Bioscience Vol.28 No.3

We previously demonstrated that bovine subcutaneous preadipocytes promote adipogenic gene expression in muscle satellite cells in a co-culture system. Herein we hypothesize that saturated fatty acids would promote adipogenic/lipogenic gene expression, whereas mono- and polyunsaturated fatty acids would have the opposite effect. Bovine semimembranosus satellite cells (BSC) and intramuscular preadipocytes (IPA) were isolated from crossbred steers and cultured with 10% fetal bovine serum (FBS)/ Dulbecco’s Modified Eagle Medium (DMEM) and 1% antibiotics during the 3-d proliferation period. After proliferation, cells were treated for 3 d with 3% horse serum/DMEM (BSC) or 5% FBS/DMEM (IPA) with antibiotics. Media also contained 10 μg/mL insulin and 10 μg/mL pioglitazone. Subsequently, differentiating BSC and IPA were cultured in their respective media with 40 μM palmitic, stearic, oleic, or linoleic acid for 4 d. Finally, BSC and IPA were single- or co-cultured for an additional 2 h. All fatty acid treatments increased (p = 0.001) carnitine palmitoyltransferase-1 beta (CPT1β) gene expression, but the increase in CPT1β gene expression was especially pronounced in IPA incubated with palmitic and stearic acid (6- to 17- fold increases). Oleic and linoleic acid decreased (p = 0.001) stearoyl-CoA desaturase (SCD) gene expression over 80% in both BSC and IPA. Conversely, palmitic and stearic acid increased SCD gene expression three fold in co-cultured in IPA, and stearic acid increased AMPKα gene expression in single- and co-cultured BSC and IPA. Consistent with our hypothesis, saturated fatty acids, especially stearic acid, promoted adipogenic and lipogenic gene expression, whereas unsaturated fatty acids decreased expression of those genes associated with fatty acid metabolism.