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      • KCI등재

        체질에 따른 식사요법이 체중과다 및 비만에 미치는 영향

        허봉수,백숙은 동아시아식생활학회 1998 동아시아식생활학회지 Vol.8 No.3

        This study was conducted in order to investigate the effect of diet therapy on over weight and obese humans in Korea Subseng Research Institute from January 1, 1994 to August 31, 1997. The constitutions of subjects were classified mild negative, strong negative, mild positive and strong positive respectively by ecology and O- ring test. These results were obtained from the subjects who practiced at least 75% diet therapy recommended for over weight and obese human for 14~400days. The constitutions of over weight and obese human by Relative Body Weight (RBW≥110%) were 89 mild negative humans, 62 strong negative humans, 56 mild positive humans and 30 strong positive humans. The constitutions of over weight and obese human by Body Mass Index(BMI ≥25) were 77 mild negative humans, 50 strong negative humans 46 mild positive humans and 23 strong positive humans. The negative subjects were higher than the positive subjects on over weight and obese humans. The diet therapy related to constitution on over weight and obese humans showed RBW reduction of 6.73±0.53 on mild negative human, 7.78±1.69 on strong negative human, 6.94±0.76 on mild positive human, and 7.80±1.15 on strong positive human at p<0.001 by student paired t-test. The diet therapy related to constitution on over weight and obese humans showed BMI reduction of 1.47±0.12 on mild negative humans, 1.24±0.11 on strong negative humans, 1.59±0.17 on mild positive humans, and 1.66±0.30 on strong positive humans at p<0.001 by student paired t-test.

      • 김치 추출물에 의한 Aflatoxin B_1의 돌연변이 억제 효과

        황승영,허영미,최영현,이숙희,박건영,이원호 부산대학교 유전공학연구소 1997 분자생물학 연구보 Vol.13 No.-

        The inhibitory effects of Kimchi extracts on the mutagenicity induced by aflatoxin B₁(AFB₁) in Salmonella and Drosophila assay systems were studied. The kimchi extracts had inhibitory activity for His^+ to His^+ reverse-mutations induced by AFB₁acting on S. typhimurium TA98. A similar inhibitory effect was detected in somatic cell mutation assaying system of D. melanogaster. In Drosophila wing hair spot test, mutant clone frequency induced by AFB₁was consideranly inhibited by the kimchi extracts. These facts suggest that kimchi rxtracts can inhibit gene mutation, deletion, mititic chromosomal recombination and suppress the formation of cancer and mutation by DNA damage.

      • 청국장 발효중 당성분 변화에 관한 연구

        이상건,허윤행,서정숙 서울保健大學 1984 論文集 Vol.4 No.1

        Bacillus natto에 의한 대두의 발효시간에 따른 당성분의 함량 변화는 다음과 같다. 1. 증자 대두의 주요 당은 stachyose (4.27%), raffinose (1.30%), maltose (0.56%), galactose(2.38%) 와 glucose (0.18%)이였으며 stachyose와 galactose 함량이 가장 높았다. 2. 0~24시간 발효에서 stachyose 함량이 현저하게 증가하였고, rhamnose & xylose, f-ructose와 ribose는 비로소 생성 되었으며, maltose와 galactose 함량은 계속적인 감소 현상이었다. 3. 증자 대두의 당보다 24시간 발효후의 당이 증가하였고 48시간 발효에서 전체적인 감소현상 이었으며 72시간 후의 당함량은 증가하는 경향이었다. 4. 발효 48~60 시간에서 출국이 적합하였다. Fermentation was carried out on steamed soybeans with a selected Bacillus that is Bacillus natto distributed from KFCC, while change of sugar content was follows: 1. Weight of sugars in steamed soybean were stachyose(4.27%), raffinose (1.30%), maltose (0.56%), galactose (2.38%) and glucose (0.18%), the highest ammount of sugars were stachyose and galactose. 2. During the fermentation 0-24hours, stachyose content increased of over that steamed soybean, while rhamnose xylose, fructose and ribose for the first time were formed and amounts of maltose and galactose had bean decreased continuosly. 3. Sugars contents almost increased after fermented 24hours rather than those contents of steamed soybeans, had bean increased, but after formented 48hours generally had bean disappeared and those contents with 72hours had been increased again. 4. According to fermentation during 48-60hours, conclusion of Chung kuk-jang koji was appropriate.

      • 21세기의 국제 경쟁력 강화를 위한 교과 교육의 과제

        이종희,김현자,전숙자,최연희,허명 이화여자대학교 교육대학원 1996 교과교육연구 Vol.5 No.-

        The purpose of this study is to provide suggestions for the innovation of Korean secondary education. The suggestions were dervied from in - depth study regarding various subjects taught in secondary school, such as Korean language, Mathematics, English, Social Studies and Science. Five kinds of questionnaires were developed and answered by a total of 728 secondary teachers. The teachers were selected nation-wide by stratified cluster sampling method. Major results of this study are as follows : A student-centered teaching model of Korean language focusing on the improvement of creative and critical thinking was developed. Examples of effective teaching method for developing mathematical literacy were presented. Some suggestions for improving English education were proposed ; The curriculum should be established by both the top- down process from the educational administers and the curriculum developers, and the bottom-up process from the teachers : furthermore, the teachers should be allowed to adapt it for their own classes. Each school should be able to choose class- types; for example, small classes with less than 25 students, large classes with around 50 students, class placement by the students' proficiency, or team teaching. Multimedia English classrooms will be needed for more effective whole-class activities, group work, and individual work to overcome the problems with too many students in a class or with students with various proficiency in a class. The testing system should be changed completely, The entrance examinations for higher- level schools or nation-wide written tests should be abolished. Then, each city or district should have a center for testing and developing teaching aids to help teachers by providing listening test items and teaching aids, and administering direct testing for speaking or writing. Teacher qualifying examinations and reeducation programs for teachers should be changed to have better-qualified English teachers for the 21st C. A curricular and instructional model emphasizing the improvement of students' ability to dealing with various social problems was proposed. 5) Various problems and issues in current science education were identified, and detailed suggestions to solve the problems and issues were proposed, which include entrance examinations, teacher education, curriculum development, gifted-student education and educational environment.

      • KCI등재

        수집지가 다른 홍화자원의 형태적 및 생화학적 특성 변이

        Jung Sook Sung,Ho Cheol Ko,On Sook Hur,Sang Gyu Kim,Jung Ro Lee,Binod P. Luitel,Yong Hwa Lee,Young Seok Jang,Jae Gyun Gwag,Hyung Jin Baek,Kyoung Yul Ryu 한국국제농업개발학회 2016 韓國國際農業開發學會誌 Vol.28 No.1

        One hundred seventy two accessions of safflower, collected in four countries were investigated for their morphological and biochemical characters in 2014. The accessions were categorized into two groups; South-Central (S-C) Asia and South-West (S-W) Asia, and each group was represented the accessions of two countries. Variation in morphological and biochemical characters was observed between two groups of accessions. The average value of seed weight and range of variability were higher in S-C Asia accessions while S-W accessions exhibited the variation in plant height, leaf length and days to flowering. The average value of oleic and total oil content were higher in S-C Asia accessions, and the values were 19.8%, and 231.4 mg.g-1, respectively, while the range of variability for total oil content was higher in S-W accessions. Plant height exhibited a significant positive correlation with days to flowering (r = 0.625**). Palmitic acid had positively correlated with stearic acid (r = 0.282**) and linoleic acid (r = 0.444**). Oleic and linoleic acid showed a strong negative correlation (r = -0.977**). The first three principal components explained 57% of the total variation. Morphological and biochemical variation exist in different groups of accessions could be useful to breeder for developing new safflower cultivars with high oil quantity and quality.

      • KCI등재

        Comparison in Antioxidant Activities and Total Polyphenol Contents of Safflower (Carthamus tinctorius L.) Germplasm Collection

        Jung Sook Sung,Ho Cheol Ko,On Sook Hur,Sang Gyu Kim,Jung Ro Lee,Binod P. Luitel,Jae Gyun Gwag,Hyung Jin Baek,Kyoung Yul Ryu 한국국제농업개발학회 2015 韓國國際農業開發學會誌 Vol.27 No.3

        사우디아라비아 북부지역에서 수집된 홍화 총 100자원에 대 한 총폴리페놀 함량 및 항산화 활성을 평가하여 항산화활성이 높은 홍화자원을 선발하고자 연구를 수행하였으며 그 결과는 다음과 같다. 1. 총 100자원의 홍화유전자원에 대한 총폴리페놀 함량은 14.2 ± 0.41 μg GAE mg−1dw에서 81.6 ± 1.56μg GAEmg−1dw 까지 분포하였다. DPPH 라디컬 소거능은 1.6 ± 0.07 μg ASC mg−1 dw에서 14.1 ± 0.23 μg ASCmg−1 dw까지 활성을 나 타냈다. ABTS 활성은 34.5 ± 0.70 μg Trolox mg−1 dw에서 156.5 ± 3.06 μg Trolox mg−1 dw까지 평가되었다. 항산화활성 을 측정한 DPPH와 ABTS 활성간에는 상당한 유의성(r = 0.954**)을 보였다. 2. 홍화자원 100자원의 총폴리페놀 함량 및 항산화활성 결 과값에 대한 상호관계를 분석하여 활성이 높은 그룹(Group1)을 얻었다. Group1에 포함된 8개의 홍화자원은 나머지 그룹에 속한 자원들에 비해 항산화활성이 높았으며, 이중 K185841, K185879, K185863은 Group1내의 다른 자원들보다도 항산화 활성이 상당히 높아 홍화육종이나 기능성물질연구에 좋은 소 재가 될 것으로 사료된다. This study was undertaken to select genetic resources of safflower with high antioxidant activities. A total of 100 accessions were obtained from the National Agrobiodiversity Center (NAC) of Korea. Total polyphenol contents (TPC) and antioxidant activities of 1,1-diphenyl-2-picryl-hydrazil (DPPH) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) in 75 % ethanol seed extract of safflower germplasm were determined. TPC ranged from 14.2 ± 0.41 to 81.6 ± 1.56 μg GAE mg-1dry weight (dw). Safflower seed extracts showed variation in DPPH antioxidant activities ranging from 1.6 ± 0.07 to 14.1 ± 0.23 μg ASC mg-1 dw. Antioxidant activities of ABTS ranged from 34.5 ± 0.70 to 156.5 ± 3.06 μg Trolox mg-1 dw. ABTS values showed significant positive correlation (r=0.954**) with DPPH activity. Group I (8 accessions) having high antioxidant activities were obtained by the matrix of calculated distances of TPC and antioxidant activities. K185841, K185879, and K185863 among group I germplasm had higher TPC and antioxidant activities than other accessions. These genotypes are potential sources of natural antioxidants. Therefore, this study provides valuable information for safflower breeders and growers to develop new varieties and produce functional foods.

      • KCI등재
      • SCIESCOPUSKCI등재

        Characterization of Osh3, an Oxysterol-binding Protein, in Filamentous Growth of Saccharomyces cerevisiae and Candida albicans

        Hur, Hyang-Sook,Ryu, Ji-Ho,Kim, Kwang-Hoon,Kim, Jin-Mi The Microbiological Society of Korea 2006 The journal of microbiology Vol.44 No.5

        OSH3 is one of the seven yeast homologues of the oxysterol binding proteins (OSBPs) which have the major binding affinity to the oxysterols and function as regulator of cholesterol biosynthesis in mammals. Mutational analysis of OSH3 showed that OSH3 plays a regulatory role in the yeast-to-hyphal transition through its oxysterol-binding domain in Saccharomyces cerevisiae. The OSH3 gene was also identified in the pathogenic yeast Candida albicans. Deletion of OSH3 caused a defect in the filamentous growth, which is the major cause of the C. albicans pathogencity. The filamentation defect of the mutation in the MAPK-associated transcription factor, namely $cph1{\Delta}$ was suppressed by overexpression of OSH3. These findings suggest the regulatory roles of OSH3 in the yeast filamentous growth and the functional conservations of OSH3 in S. cerevisiae and C. albicans.

      • KCI등재

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