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Ryu, Mikyung,Jo, Jaeseong,Lee, Yunhwan,Chung, Yoon-Sok,Kim, Kwang-Min,Baek, Weon-Chil Oxford University Press 2013 Age and ageing Vol.42 No.6
<P><B>Objective:</B> this study examined the association of physical activity with sarcopenia and sarcopenic obesity among the community-dwelling Korean elderly.</P><P><B>Methods:</B> subjects consisted of 2,264 aged 65 years or older in the 2008–09 Korea National Health and Nutrition Examination Survey. Sarcopenia was defined as 2 SD below the mean of the appendicular skeletal muscle/weight for healthy young adults. Obesity was defined as waist circumference ≥90 cm for men and ≥85 cm for women. Levels of physical activity were classified using the metabolic equivalent task method.</P><P><B>Results:</B> the prevalence of sarcopenia was 12.1% in men and 11.9% in women. Among those with sarcopenia, obesity was prevalent in 68.3% of men and 65.0% of women. Adjusting for all covariates, compared with those with low physical activity, men who engaged in moderate and high activity were 38% and 74%, respectively, less likely to have sarcopenia (<I>P</I><SUB>trend</SUB> < 0.001). In women, the relationship between physical activity and sarcopenia was not significant. For sarcopenic obesity, men participating in moderate [odds ratio (OR) = 0.47; 95% confidence interval (CI) 0.26–0.87] and high (OR = 0.27; 95% CI: 0.12–0.60) physical activity, compared with low activity, had significantly lower risk (<I>P</I><SUB>trend</SUB> = 0.001). In women, high physical activity was associated with a lower risk of sarcopenic obesity (OR = 0.43; 95% CI: 0.22–0.86).</P><P><B>Conclusion:</B> physical activity is associated with a reduced risk of sarcopenia and sarcopenic obesity in older Korean adults. There were gender differences in the relationship, with stronger associations observed in men than in women.</P>
Ryu, Mikyung,Gombojav, Bayasgalan,Nam, Chung Mo,Lee, Yunhwan,Han, Kimyoung Japan Epidemiological Association 2014 Journal of epidemiology Vol.24 No.4
<P><B>Background</B></P><P>Although binge drinking and high resting heart rate independently affect cardiovascular and all-cause mortality risk, the combined effect of these two risk factors and their interaction has rarely been studied. This study examined the association between binge drinking and cardiovascular and all-cause mortality and evaluated the potential modifying effect on this association of resting heart rate in Korean men.</P><P><B>Methods</B></P><P>Men aged 55 years or older in 1985 (<I>n</I> = 2600) were followed for cardiovascular and all-cause mortality for 20.8 years, until 2005. We estimated hazard ratios (HRs) for cardiovascular and all-cause mortality by binge drinking and resting heart rate using the Cox proportional hazard model.</P><P><B>Results</B></P><P>Heavy binge drinkers (≥12 drinks on one occasion) with elevated resting heart rate (≥80 bpm) had a HR of 2.25 (95% confidence interval [CI], 1.47–3.45) for death from cardiovascular disease and 1.37 (95% CI, 0.87–2.14) for all-cause mortality compared to the reference group (non-drinking and resting heart rate 61–79 bpm). The HRs of dying from cardiovascular disease increased linearly from 1.36 to 1.52, 1.71, and 2.25 among individuals with resting heart rate greater than or equal to 80 bpm within the four alcohol consumption categories (non-drinking, non-binge, moderate binge, and heavy binge), respectively.</P><P><B>Conclusions</B></P><P>Our findings suggest that, among older Korean men, heavy binge drinkers with an elevated resting heart rate are at high risk for cardiovascular and all-cause mortality.</P>
CO<sub>2</sub>-assisted hydrothermal reactions for ginseng extract
Ryu, Jebin,Yoon, Junho,Ryu, Seungmi,Kang, Seokyung,Kang, Mikyung,Kim, Byung-Soo,Lee, Youn-Woo Elsevier 2018 The Journal of supercritical fluids Vol.135 No.-
<P><B>Abstract</B></P> <P>CO<SUB>2</SUB>-assisted hydrothermal reactions were performed for the conversion of intact ginsenosides to the more bioactive ginsenosides, (S)-Rg3, (R)-Rg3, Rk1, and Rg5. The yields of the transformed ginsenosides and anticancer activities were compared for the three processes: conventional steaming, hydrothermal processing, and CO<SUB>2</SUB>-assisted hydrothermal processing. In the CO<SUB>2</SUB>-assisted hydrothermal process, approximately 2 times higher yields of transformed ginsenosides were obtained within 30 min compared to the steaming process, which requires autoclaving for 3 h, at the same temperature of 120 °C. These improvements were attributed to the homogeneous reaction condition and the <I>in-situ</I> generation of carbonic acid. Moreover, the CO<SUB>2</SUB>-assisted hydrothermally processed ginseng showed the highest antiproliferative effects on HT 1080 and MDA-MB-231 cells by stimulating apoptosis. Due to the higher yields of transformed ginsenosides, similar antiproliferative effects could be obtained using only 10–20% of the amounts used in previous studies.</P> <P><B>Highlights</B></P> <P> <UL> <LI> CO<SUB>2</SUB>-assisted hydrothermal reactions were performed for intact ginsenoside conversion. </LI> <LI> Transformed ginsenoside yields were highly increased within a short time. </LI> <LI> The E<SUB>a</SUB> for the decomposition rate of intact ginsenosides was decreased by 16.7%. </LI> <LI> Apoptosis stimulation elicited anticancer effects on HT 1080 and MDA-MB-231 cells. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Association between Alcohol Intake and Abdominal Obesity among the Korean Population
Mikyung Ryu,Heejin Kimm,Jaeseong Jo,Sun Ju Lee,Sun Ha Jee 한국역학회 2010 Epidemiology and Health Vol.32 No.-
OBJECTIVES: Although abdominal obesity has been reported to be highly related with alcohol intake, the results are still inconclusive. Therefore, this study was conducted to explore the association between alcohol and abdominal obesity among the Korean population. METHODS: This study included 8,603 participants (men: 5,195, women: 3,408) aged 30 to 87 who visited the health promotion centers in Seoul for routine health examinations from April, 2006 to June, 2007. Abdominal obesity was defined as WC ≥90 cm for men and ≥85 cm for women in accordance with the Korean Society for the Study of Obesity. For ever drinkers, total alcohol consumption in grams was classified into four groups (group 1, non-drinkers; group 2, 1-10 g of alcohol per day; group 3, 11-20 g of alcohol per day; and group 4, over 20 g of alcohol per day). RESULTS: The mean age of the study population was 45.4 yr old (men) and 45.3 yr (women). The average waist circumference was 85.3 cm in men and 75.3 cm in women. A high alcohol intake was associated with high waist circumference in both genders. In multivariate analysis, the group of men and women drinkers consuming >20 g in a day had a large waist circumference compared with men and women non-drinkers. CONCLUSION: This study showed that a high alcohol intake was related to high waist circumference. Such association remained independently even after adjustment for smoking, which is strongly related to abdominal obesity.
Prospective Diary Survey of Preschool Children's Social Contact Patterns: A Pilot Study
오향순,Mikyung Ryu 한국아동간호학회 2020 Child Health Nursing Research Vol.26 No.4
Purpose: This pilot study aimed to describe children's social contact patterns and to analyze factors related to their social contacts. Methods: The participants were 30 children aged ≥13 months to <7 years, whose teachers at childcare centers and parents at home were asked to maintain diaries of their social contacts prospectively for 24 hours. Data were collected from November 30, 2018, to January 7, 2019. Results: The 30 participating children were in contact with 363 persons in a 24-hours period (mean, 12.1±9.1). The number of contacts showed significant relationships with day of the week (p<.001), number of family members/cohabitants (p=.015), area of residence (p=.003), and type of housing (p=.002). A multiple regression model showed significantly higher numbers of contacts on weekdays (B=10.64, p=.010). Physical versus non-physical types of contact showed significant differences in terms of duration, location, and frequency (p<.001). The duration of contacts showed significant relationships with their location and frequency (p<.001), while the frequency of contacts was significantly related to their location (p<.001). Conclusion: This is the first survey describing the characteristics of Korean preschool children's social contacts. Further large-scale social contact studies of children should be conducted.
이용자의 방송프로그램 VOD 콘텐츠 정책 인식에 미치는 요인에 대한 연구
김미경 ( Mikyung Kim ),류기상 ( Kisang Ryu ) 현대사진영상학회 2016 현대사진영상학회논문집 Vol.19 No.2
본 연구 목적은 VOD 방송콘텐츠 규제를 어떻게 해야 할 지에 대해 이용자가 태도에 영향을 미치는 요인을 통계적으로 분석하는 것이다. 본 연구는 VOD콘텐츠의 사회적 영향력에 대한 이용자 지각, VOD콘텐츠 이용시간, VOD콘텐츠 장르별 이용빈도, 사회인구통계학적 특징을 측정도구로 하여 VOD 방송 콘텐츠 규제에 대한 이용자 태도를 분석하였다. 조사는 13세 이상 1000명을 면접인터뷰를 통해서 이루어졌으며, 데이터는 VOD재방송 콘텐츠를 이용한 적이 있는 응답자를 통해서 수집되었다. 수집된 데이터는 다중회귀분석을 통해서 분석되었으며 연구결과는 VOD콘텐츠의 사회적 영향력에 대한 이용자의 지각과 이용자 VOD콘텐츠 이용시간은 VOD방송콘텐츠 규제 에 영향을 미치는 주요한 요인으로 나타났다. VOD콘텐츠 장르별 이용빈도에서 보면 음악프로그램이 VOD방송콘텐츠 규제와 상관성이 있는 것으로 나타났다. 또한 VOD 음악프로그램과 VOD 드라마를 자주 이용하는 이용자들은 이들 콘텐츠의 영향력이 크다고 믿는 것으로 나타났다. 사회인구통계학적 특징과 VOD방송콘텐츠 규제간의 관계에서는 성별의 차이만이 상관성이 있는 것으로 나타났다.