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유씨소요산(柳氏逍遙散)과 유씨귀비탕(柳氏歸脾湯)의 항(抗)스트레스 효과(效果)에 관(關)한 임상적(臨床的) 연구(硏究)
이석준,류희영,Lee Sek-Jun,Lyu Heui-Yeong 대한한방신경정신과학회 1994 동의신경정신과학회지 Vol.5 No.1
The objective of this paper is to verify clinical effects of Lyu's Soyosan(柳氏逍遙散) and Lyu's Kwipithang(柳氏歸脾湯). They were prescribed to the enperimental student group suffering from mental stress and annoyed by psychological instability. From the biochemical examination before and after medication, we measure the amount of hormonal variation in thyroid hormone(TSH, $T_4$) and adrenocortical hormone(ACTH, cortisol) The results are as follows. 1. The average of self-rating anxiety scale(SAS) in test group is $41.00\;{\pm}\;7.84$. This value is statistical significant and higher than one of normal person(age 20-39). The average of a global assesment of recent stress(GARS) scale is $28.62\;{\pm}9.00$. There is statistical correlation coefficient between SAS and GARS (p < 0.001). 2. Both Lyu's Soyosan(柳氏逍遙散) and Lyu.s Kwipithang (柳氏歸脾湯) groups show statistically significant reduction of total cholesterol and triglyceride level in serum lipid after ten day medication. 3. It is observed that Lyu's Soyisan(柳氏逍遙散) and Luy's Kwipithang (柳氏歸脾湯) groups have increasing tendency of TSH. The statistically significant reduction of $T_4$ was found in two groups after ten day medicaton. 4. It is observed that Lyu's Soyosan(柳氏逍遙散) and Lyu's kwipithang (柳氏歸脾湯) group have statistically significant reduction of serum cortisol level after ten day medication, Both groups have statistically significant reduction of plasma ACTH level after twenty day medication. From these results, it is verified that both Lyu's Soyosan(柳氏逍遙散) and Lyu's Kwipithang (柳氏歸脾湯) have anti-stress effects against psychological instability and mental stress. The Lyu's Soyosn(柳氏逍遙散) shows special effectiveness in depression of liver-energy(肝氣鬱結) and the Lyu's Kwipitang (柳氏歸脾湯) is also effective in deficiency heart-blood(心血不足).
Lyu,Jae-Il,Lee,Sun-Ha,Lim,Keun-Chul,Kim,Gil-Ja,Yang,Deok-Chun,Bae,Chang-Hyu 한국자원식물학회 2003 Plant Resources Vol.6 No.3
Genetic diversity of 45 tea accessions from Korea, Japan, China and Taiwan was investigated by using RAPD analysis. Out of the eighty primers screened, twenty primers generated 99 polymorphic bands with a polymorphic rate 87.0%. The size of the amplified fragments ranged from about 3,138 bp to 520 bp. By cluster analysis, all of the 45 accessions can be grouped into five groups. Over 90% of the 32 Korean accessions belonged to group II, III, IV and V. Moreover, newly developed Korean cultivars (accession no. 13, 14 and 15) belonged to very different group compared with any other Korean accessions. Among the Korean accessions, the minimum genetic similarity 0.500 was obtained between accession no. 17 and 37 and the largest genetic similarity 0.912 between no. 20 and 21.
[PG-0003] Phytochemical compounds and antioxidant activates of Hop (Humulus lupulus L.) cultivars
Jae Il Lyu(Jae Il Lyu ),Jaihyunk Ryu(Jaihyunk Ryu ),Tae Hyun Ha(Tae Hyun Ha ),Jun-Hyung Lee(Jun-Hyung Lee ),Sang Hoon Park(Sang Hoon Park ),Hee Kyoung Kang(Hee Kyoung Kang ),Joon-Woo Ahn(Joon-Woo Ahn 한국육종학회 2022 한국육종학회 공동학술발표집 Vol.2022 No.-
Lyu, Ji-Hyo,Lyu, Sun-Ae,Yoon, Hwa-Jung,Ko, Woo-Shin The Physiological Society of Korean Medicine and T 2008 동의생리병리학회지 Vol.22 No.6
In previous report, Seungmagalgeun-tang (SGT) could exert its anti-inflammatory actions in the BV-2 microglial cells. However, study on the anti-inflammatory effect of SGT in mast cells has not been identified. Therefore, we examined on the anti-inflammatory effect of SGT on the phorbol 12-myristate 13-acetate (PMA) and calcium ionophore A23187-induced rat basophilic leukemia (RBL-2H3) cells. SGT inhibited the release of ${\beta}$-hexosaminidase and secretion and expression of pro-inflammatory cytokines such as tumor necrosis factor (TNF)-${\alpha}$ and interleukin (IL)-4 on RBL-2H3 cells, without affecting cell viability. The protein expression level of nuclear factor (NF)-${\kappa}B$ (p65) was decreased in the nucleus by SGT. In addition, SGT suppressed the degradation of inhibitory protein $I{\kappa}B-{\alpha}$ protein, the activation of p38 mitogen-activated protein kinase (MAPK), and the expressions of cyclooxygenase (COX)-2 mRNA and protein level in RBL-2H3 cells. These results suggest that SGT could be involved anti-allergic effect by control of NF-${\kappa}B$ (p65) translocation into the nucleus through inhibition of $I{\kappa}B-{\alpha}$ degradation and suppression of COX-2 expression.
A Study of Psychiatric Impotance on the Openning of Nae-ui-won(內醫院)
Lyu Yong-Su,Lyu Hui-Yong The Korean Society of Oriental Neuropsychiatry 1991 동의신경정신과학회지 Vol.2 No.1
내의원(內醫院)은 병원과 약국을 겸비한 일종의 궁중의료기관으로 의사를 비롯하여 여러의원들이 임금과 왕비 및 왕자들의 약을 조제하여 달이던 곳으로, 일명 내국(內局) 또는 약원(藥院)이라고 내의원 앞에 예시되어 있다. 그러나 내의원은 현재 그 내용이 전해지지 않고, 단지 관광지의 유물로만 여겨지고 있다. 현재의 내의원은 창덕궁(昌德宮)에 위치하고 있다. 내의원은 창덕궁의 돈화문(敦化門)을 지나, 인정전(仁政殿)을 거쳐 희정당(熙政當) 좌측에 있으며, 왕비의 거처인 대조전에 가장 가까이 자리잡고 있다. 내의원은 조선왕조 세종25년(1443)에 개원하게 되었으니, 이때는 정치, 문화적으로 안정이 이루어져 가는 상황이었다. 또한 당시 왕이나 왕비 기타 왕족들의 여러 가지 정신적인 갈등으로 인한 질병이 많았으며, 이로인해 전문적이고 독립적인 왕실의료기관의 필요성에 의해 내의원이 독립적인 개원이 이루어졌으리라 사료된다. 이로인하여 저자가 내의원에 관한 자료조사와 실제답사를 통하여 다음과 같은 사실을 알수 있었다. 1) 내의원의 개원은 조선왕조 초기 중앙의료질서 성립을 통한 봉건왕조의 절대왕권확립을 의미함으로 사료된다. 2) 내의원의 위치가 창덕궁의 중심부에 위치하고, 특히 어전(御殿)과 내전(內殿) 가까이에 위치함은 왕실의 질병을 신속하고도 중요하게 다루기 위함으로 사료된다. 3) 특히 의인을 내전에서도 대조전(大造殿) 가까히 둔것은 왕실의 질병중 왕비의 정신신체질환의 치료를 위함으로 사료된다. 4) 내의원의 진료형태는 왕진(往診)이었으며, 이는 당시 의원신분이 중인층이었음으로 사료된다. 5) 내의원의 이용중에서 평민에게는 왕명에 의해서만 이루어졌음으로 사료된다.
류나현 ( Lyu Na Hyeon ),최미영 ( Choe Mi Yeong ),류연주 ( Lyu Yeon Ju ),조현종 ( Jo Hyeon Jong ),이용세 ( Lee Yong Se ),이영득 ( Lee Yeong Deug ),정종배 ( Jeong Jong Bae ) 한국환경농학회 2003 한국환경농학회지 Vol.22 No.4
Silicon is known to accumulate in plants and results in greater resistance to diseases and insect pests. In this study, we investigated the effect of silicate fertUizer applied in soil on the development of powdery mildew of oriental melon Oriental melon seedlings of four-leaf stage were transplanted and grown in a plastic film house. silicate fertilizer was applied to maintain soil available SiO₂ level of 200 ㎎/㎏ one week before transplanting. Fungicide trinumizol was sprayed three times; one, two, and three weeks after transplanting. Sphaerotheca fuliginea was inoculated 2 weeks after transplanting. The number of infected leaf and the number of fungal colony in leaves were measured one, two, and three weeks after the inoculation. Three weeks after the fungal inoculation, in the treatment of fungicide triflwnhl, infected leaf numbem and number of colony per leaf were reduced by 10 and 58% respectively. In the silicate fertilizer treatment, infected leaf numbers and numbers of colony per infected leaf were suppressed only by 6 and 16%, respectively, and the efficacy was lower than that of the fungicide triflumizol. The combined treatment of silicate fertilizer and the fungicide suppressed powdery mildew more effectively, and infected leaf numbem and numbem of colony per leaf were reduced by 31 and 80%, respectively. These results indicate that although silicate fertilizer itself is not much effective in the suppression of powdery mildew, it can significantly enhance the efficacy of the fungicide.