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      • 複制中國書畵文物的歷史和現狀及複制工藝技術

        曹靜樓,郭文林 용인대학교 박물관 2003 丹豪文化硏究 Vol.- No.7

        Imno(臨摹 copying) of the painting and writing in China is combined result of many closely-related elements that include Chinese cultural tradition and philosophy and substantial characteristics of Chinese paintings and calligraphy. ① Chinese rulers throughout history, under the so-called theory of 'Sungkyohuajoinlon' (成敎化助人論 to help people by educating them) often relied on paintings as a means to strengthen their governing foundation while using them to educate their subjects and people. For example, Hyojaeuisudo ≪孝子義士圖, a painting of devoted children and righteous people≫ meant the loyalty and obedience, Yulyujun ≪烈女傳, a story of virtuous women≫ was used to signify the importance of chastity in a feudal society. Paintings with such themes were met with the rulers ethics and, with the supports from the rulers, used as a means to publicize their ethics and educate their subjects and people. ② There were many rulers who were good at or loved the writing and painting in ancient China. Among many, Taizhong Li Shimin at Tang Dynasty(唐 太宗 李世民), Xianzhong Li Jiangji(玄宗 李降基), Huizhong Jo Ji at Song Dynasty (宋代 徽宗 趙佶), Xunzhong Zhu Jianshen at Ming Dynasty(明代 憲宗 朱見深), Gaozhong Hong Li at Qing Dynasty(靑代 高宗 弘力) are such examples. Development of painting and writing arts in China was achieved with the interests of rulers in them, and important eras that marked the history of Chinese painting and writing arts were created. Until the year of Huizhong(徽宗), the level of painting and writing was an important condition in deciding a governmental position. However, in ancient times, since there was a limited number of painting and writing works and lack of printing technology, emperors and high officials of literature had to be satisfied only with enjoying them and hoped to possess them. In the government, a special bureau was established to educate and raise the professionals who could duplicate the paintings and writings. This tendency influenced the society as a whole, and the atmosphere of reproduction of painting and writing works by duplication gradually culminated. ③ Chinese philosophy had also influenced their painting and writing arts. Chinese drawings pursue objectivity and has an expression style of Chuninhapil (天人合一, heaven and human beings are one). In Chinese drawings, artists describe the natural object and at the same time transfer their mind and feelings in them. Nature in the drawings is not just the nature as it is seen, but it is the nature observed and attained by artists and drawn from deep inside of artists. When people learn Chinese drawings for the first time, they are not taught how to describe the forms as in the western style but receive formative train in that people enter into the nature and sketch. This is the reason why artists, when copying the works in the past, are able to obtain the feelings of nature and learn various brush techniques that are applied in Chinese drawings. Therefore, copying is a significant method to learn Chinese drawings. For example, SunMyo(線描 line description) has a certain form, and a famous ShipPalMyo (十八描 18 descriptions) including ChulSunMyo(鐵線描), YuSaMyo (遊絲描), NanYupMyo (蘭葉描), YuYupMyo (柳葉描), JoEuiMyo (曹衣描) was created. Since these lines don't exist in natural objects, it is impossible to learn them through sketching. They can be learned only by copying the works in the past, in which they equates with various drawing styles that are applied when painting various objects. For example, JunBup(준法 technique to express the feel of the surface as it is) used for landscape drawings is helpful when expressing the touch and feelings of various rocks. For example, BuByukJun(斧劈준) or WooJumJun(雨點준) are good for expressing the characteristics of Chinese northern landscape, PiMaJun(披痲준) or MiJumJun(米點준) for Chinese southern landscape. This JunBup does not exist in natural objects such as mountain or rock, and artists can learn the right JunBup for various rocks through copying the works of the past. ④ Traditional thinking that stresses the relationship between a teacher and disciple in Chinese culture had also influenced Chinese painting and writing arts. When people beging to learn Chinese drawings, they must copy the works of their teacher. Therefore, when other people look at the drawings, they know who is with which teacher and which school. The drawings of certain artists are used as an educational purpose when students learn drawings for copying. For example, SaSaengJinBuDo ≪寫生珍禽圖≫ by Huang Jun (黃筌) in Song Dynasty was inherited to his son and learned as a work for copying. Each word in Immo(臨摹), according to the explanation in the ancient literature, has a separate meaning, Mo(摹 to copy) means Tap(榻 to copy), and Im(臨 to overlook) means Sa(寫 to write). Current meaning of Im(臨) is, while looking at the original drawing, to understand deeply and in details. When doing it, not only the techniques of brush, ink, and color but also the compositional characteristics should be thoroughly studied in order to completely familiarize with the form and line of the original drawing. And then, it has to be reproduced on another paper in one moment, and the copy does not have to be and can not be exactly the same as the original. Im(臨), based upon the complete understanding of the original, is to complete the copy with one energy without looking at the original. Mo(摹) is, while placing a thin paper right over the ancient drawing book, to copy both thick and thin lines, and Mo(摹)'s meaning in copying of a painting (摹畵) is the same. In ancient times, Mo(摹) was replaced with Mo(模 to imitate) or Mu(撫 to stroke). In other words, a transparent paper is placed over the original, the first copy is accurately made, the original is removed, drawing paper is placed over the first copy, and drawing is done in details while referring the original. Two words, Im(臨) and Mo(摹), originally impose a separate meaning and cant be one word, but they are habitually used as one word. Mo(摹) used in current China cant be Im (臨) but has to be called as Motap (摹榻). Especially, copying and counterfeiting are fundamentally different and can't be used as same meaning. The purpose of copying is a complete reproduction of energy and form of the original, and it is to conserve and actively publicize the original. The purpose of counterfeiting is to gain profits while falsely stating someone else's name as his or her own, and it includes the meaning of damaging the original. They also have difference in using the technique. The work of copying is faithful to the original and completely reproduce the smallest detail. People producing the copies must perfectly understand the spirit and form of the original, and successful copies should contain both the form and spirit. Rather, counterfeit is not based on the original but freely drawn upon studying a certain brush style of ones own. As a result, artists of counterfeit who are very well aware of the brush style used by the original artist are famous artists and might be the person who lives the same period with or the disciple of the original artist. Paintings produced for the purpose of counterfeiting possibly be the fraud and trouble to judge the authenticity of the work in a later period. Copying project of painting and writing at the Palace Museum is to replace the original work with the copied one by the time of difficulty in exhibiting the original, which is the best way to conserve the original. Copying of ancient paintings and calligraphy does not only mean the line description, outlining, coloring), or usage of ink. It is a very difficult process of re-creation that requires sincerity and efforts. Since the Palace Museum has started the copying project in 1950s, top artists are putting their efforts to copy and duplicate highly-valuable cultural artifacts. They have copied famous drawings of Qin, Tang, Song and Yuan dynasty with strict working attitude and exquisite techniques. Famous Chungmyungsanghudo≪淸明上河圖≫, Hanheejaeyayeondo ≪韓熙載夜宴圖≫, Guasukpyungwondo≪과石平遠圖≫ by Kwak Hee(郭熙), and Chunggeumdo ≪聽琴圖≫ by Jo Gil (趙佶) are such examples. Not many professionals are working for the copies in China. There were few in the Shanghai(上海) and Nanjing(南京) Museum during 1980s, but they are no longer there with various reasons. In Dunhuang(敦煌) and Xian (西安), frescoes are mainly being replicated. The quality of professionals who work to copy at the Palace Museum are the best in its technique and size and cannot be compared to other museums. Copying one painting successfully requires a lot of preparations. When producing the copies, it takes from few days to several years. Thus, safety of the original should be guaranteed, and there should not be done even a small damage. But observing the original should be convenient, and copying process should be progressed with many attentions.

      • KCI등재

        Cytoprotective Effect of Taurine against Hydrogen Peroxide- Induced Oxidative Stress in UMR-106 Cells through the Wnt/β- Catenin Signaling Pathway

        ( Jing Lou ),( Donghe Han ),( Huihui Yu ),( Guang Yu ),( Meihua Jin ),( Sung-jin Kim ) 한국응용약물학회 2018 Biomolecules & Therapeutics(구 응용약물학회지) Vol.26 No.6

        Osteoporosis development is closely associated with oxidative stress and reactive oxygen species (ROS). Taurine has potential antioxidant effects, but its role in osteoblasts is not clearly understood. The aim of this study was to determine the protective effects and mechanisms of actions of taurine on hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>)-induced oxidative stress in osteoblast cells. UMR-106 cells were treated with taurine prior to H<sub>2</sub>O<sub>2</sub> exposure. After treatment, cell viability, apoptosis, intracellular ROS production, malondialdehyde content, and alkaline phosphate (ALP) activity were measured. We also investigated the protein levels of β-catenin, ERK, CHOP and NF-E2-related factor 2 (Nrf2) along with the mRNA levels of Nrf2 downstream antioxidants. The results showed that pretreatment of taurine could reverse the inhibition of cell viability and suppress the induced apoptosis in a dose-dependent manner: taurine significantly reduced H<sub>2</sub>O<sub>2</sub>-induced oxidative damage and expression of CHOP, while it induced protein expression of Nrf2 and β-catenin and activated ERK phosphorylation. DKK1, a Wnt/β-catenin signaling inhibitor, significantly suppressed the taurine-induced Nrf2 signaling pathway and increased CHOP. Activation of ERK signaling mediated by taurine in the presence of H<sub>2</sub>O<sub>2</sub> was significantly inhibited by DKK1. These data demonstrated that taurine protects osteoblast cells against oxidative damage via Wnt/β-catenin-mediated activation of the ERK signaling pathway.

      • SCIESCOPUSKCI등재

        Cytoprotective Effect of Taurine against Hydrogen Peroxide-Induced Oxidative Stress in UMR-106 Cells through the Wnt/β-Catenin Signaling Pathway

        Lou, Jing,Han, Donghe,Yu, Huihui,Yu, Guang,Jin, Meihua,Kim, Sung-Jin The Korean Society of Applied Pharmacology 2018 Biomolecules & Therapeutics(구 응용약물학회지) Vol.26 No.6

        Osteoporosis development is closely associated with oxidative stress and reactive oxygen species (ROS). Taurine has potential antioxidant effects, but its role in osteoblasts is not clearly understood. The aim of this study was to determine the protective effects and mechanisms of actions of taurine on hydrogen peroxide ($H_2O_2$)-induced oxidative stress in osteoblast cells. UMR-106 cells were treated with taurine prior to $H_2O_2$ exposure. After treatment, cell viability, apoptosis, intracellular ROS production, malondialdehyde content, and alkaline phosphate (ALP) activity were measured. We also investigated the protein levels of ${\beta}-catenin$, ERK, CHOP and NF-E2-related factor 2 (Nrf2) along with the mRNA levels of Nrf2 downstream antioxidants. The results showed that pretreatment of taurine could reverse the inhibition of cell viability and suppress the induced apoptosis in a dose-dependent manner: taurine significantly reduced $H_2O_2$-induced oxidative damage and expression of CHOP, while it induced protein expression of Nrf2 and ${\beta}-catenin$ and activated ERK phosphorylation. DKK1, a Wnt/${\beta}-catenin$ signaling inhibitor, significantly suppressed the taurine-induced Nrf2 signaling pathway and increased CHOP. Activation of ERK signaling mediated by taurine in the presence of $H_2O_2$ was significantly inhibited by DKK1. These data demonstrated that taurine protects osteoblast cells against oxidative damage via Wnt/${\beta}-catenin$-mediated activation of the ERK signaling pathway.

      • Alveolar bone thickness around maxillary central incisors of different inclination assessed with cone-beam computed tomography

        Yu-lou Tian,Fang Liu,Hong-jing Sun,Pin Lv,Yu-ming Cao,Mo Yu,Yang Yue 대한치과교정학회 2015 대한치과교정학회지 Vol.45 No.5

        Objective: To assess the labial and lingual alveolar bone thickness in adults with maxillary central incisors of different inclination by cone-beam computed tomography (CBCT). Methods: Ninety maxillary central incisors from 45 patients were divided into three groups based on the maxillary central incisors to palatal plane angle; lingual-inclined, normal, and labial-inclined. Reformatted CBCT images were used to measure the labial and lingual alveolar bone thickness (ABT) at intervals corresponding to every 1/10 of the root length. The sum of labial ABT and lingual ABT at the level of the root apex was used to calculate the total ABT (TABT). The number of teeth exhibiting alveolar fenestration and dehiscence in each group was also tallied. One-way analysis of variance and Tukey’s honestly significant difference test were applied for statistical analysis. Results: The labial ABT and TABT values at the root apex in the lingual-inclined group were significantly lower than in the other groups (p < 0.05). Lingual and labial ABT values were very low at the cervical level in the lingual-inclined and normal groups. There was a higher prevalence of alveolar fenestration in the lingual-inclined group. Conclusions: Lingual-inclined maxillary central incisors have less bone support at the level of the root apex and a greater frequency of alveolar bone defects than normal maxillary central incisors. The bone plate at the marginal level is also very thin.

      • KCI등재

        Endovascular Treatment for Iliac Vein Compression Syndrome: a Comparison between the Presence and Absence of Secondary Thrombosis

        Wen-Sheng Lou,Jian-Ping Gu,Xu He,Liang Chen,Hao-Bo Su,Guo-Ping Chen,Jing-Hua Song,Tao Wang 대한영상의학회 2009 Korean Journal of Radiology Vol.10 No.2

        Objective: To evaluate the value of early identification and endovascular treatment of iliac vein compression syndrome (IVCS), with or without deep vein thrombosis (DVT). Materials and Methods: Three groups of patients, IVCS without DVT (group 1, n = 39), IVCS with fresh thrombosis (group 2, n = 52) and IVCS with non-fresh thrombosis (group 3, n = 34) were detected by Doppler ultrasonography, magnetic resonance venography, computed tomography or venography. The fresh venous thrombosis were treated by aspiration and thrombectomy, whereas the iliac vein compression per se were treated with a self-expandable stent. In cases with fresh thrombus, the inferior vena cava filter was inserted before the thrombosis suction, mechanical thrombus ablation, percutaneous transluminal angioplasty, stenting or transcatheter thrombolysis. Results: Stenting was performed in 111 patients (38 of 39 group 1 patients and 73 of 86 group 2 or 3 patients). The stenting was tried in one of group 1 and in three of group 2 or 3 patients only to fail. The initial patency rates were 95% (group 1), 89% (group 2) and 65% (group 3), respectively and were significantly different (p = 0.001). Further, the six month patency rates were 93% (group 1), 83% (group 2) and 50% (group 3), respectively, and were similarly significantly different (p = 0.001). Both the initial and six month patency rates in the IVCS patients (without thrombosis or with fresh thrombosis), were significantly greater than the patency rates of IVCS patients with non-fresh thrombosis. Conclusion: From the cases examined, the study suggests that endovascular treatment of IVCS, with or without thrombosis, is effective. Objective: To evaluate the value of early identification and endovascular treatment of iliac vein compression syndrome (IVCS), with or without deep vein thrombosis (DVT). Materials and Methods: Three groups of patients, IVCS without DVT (group 1, n = 39), IVCS with fresh thrombosis (group 2, n = 52) and IVCS with non-fresh thrombosis (group 3, n = 34) were detected by Doppler ultrasonography, magnetic resonance venography, computed tomography or venography. The fresh venous thrombosis were treated by aspiration and thrombectomy, whereas the iliac vein compression per se were treated with a self-expandable stent. In cases with fresh thrombus, the inferior vena cava filter was inserted before the thrombosis suction, mechanical thrombus ablation, percutaneous transluminal angioplasty, stenting or transcatheter thrombolysis. Results: Stenting was performed in 111 patients (38 of 39 group 1 patients and 73 of 86 group 2 or 3 patients). The stenting was tried in one of group 1 and in three of group 2 or 3 patients only to fail. The initial patency rates were 95% (group 1), 89% (group 2) and 65% (group 3), respectively and were significantly different (p = 0.001). Further, the six month patency rates were 93% (group 1), 83% (group 2) and 50% (group 3), respectively, and were similarly significantly different (p = 0.001). Both the initial and six month patency rates in the IVCS patients (without thrombosis or with fresh thrombosis), were significantly greater than the patency rates of IVCS patients with non-fresh thrombosis. Conclusion: From the cases examined, the study suggests that endovascular treatment of IVCS, with or without thrombosis, is effective.

      • KCI등재

        Flow Field Analysis of Lubricating Air Film in Aerostatic Restrictor with Double U-shaped Pressure-Equalizing Grooves

        Jianlong Yin,Jing Yu,Cheng Lou,Dongsheng Li,Xiaoyan Shen,Ming Li 한국정밀공학회 2023 International Journal of Precision Engineering and Vol.24 No.2

        In an aerostatic restrictor, the presence of friction between the high-pressure air and the aerostatic restrictor wall can lead to non-uniform pressure and temperature distributions of the lubricating air film, which will affect the aerostatic restrictor performance. Therefore, explicating the pressure and temperature distributions of the lubricating air film could help to improve the characteristics and performance of the aerostatic restrictor. In this study, a theoretical model is established for the pressure and temperature distributions in the aerostatic restrictor with double U-shaped pressure-equalizing grooves, which is then compared with simulations, and finally verified by experiments. The results indicate the following. (1) The parameter distributions of the aerostatic restrictor’s air film are affected by the pressure-equalizing grooves and the orifice. (2) The air film parameter distributions are affected by the air source pressure and air film thickness. (3) The air film parameter distribution characteristics obtained from theoretical calculations, simulations, and experiments are consistent, indicating that the theoretical model is effective for studying the flow field of lubricating air film in the aerostatic restrictor. This model can also provide a theoretical basis for designing the orifice and pressure-equalizing grooves of the aerostatic restrictor, as well as selecting the air source pressure and air film thickness.

      • SCIESCOPUSKCI등재

        Major ginsenosides from Panax ginseng promote aerobic cellular respiration and SIRT1-mediated mitochondrial biosynthesis in cardiomyocytes and neurons

        Huang, Qingxia,Lou, Tingting,Lu, Jing,Wang, Manying,Chen, Xuenan,Xue, Linyuan,Tang, Xiaolei,Qi, Wenxiu,Zhang, Zepeng,Su, Hang,Jin, Wenqi,Jing, Chenxu,Zhao, Daqing,Sun, Liwei,Li, Xiangyan The Korean Society of Ginseng 2022 Journal of Ginseng Research Vol.46 No.6

        Background: Aerobic cellular respiration provides chemical energy, adenosine triphosphate (ATP), to maintain multiple cellular functions. Sirtuin 1 (SIRT1) can deacetylate peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1α) to promote mitochondrial biosynthesis. Targeting energy metabolism is a potential strategy for the prevention and treatment of various diseases, such as cardiac and neurological disorders. Ginsenosides, one of the major bioactive constituents of Panax ginseng, have been extensively used due to their diverse beneficial effects on healthy subjects and patients with different diseases. However, the underlying molecular mechanisms of total ginsenosides (GS) on energy metabolism remain unclear. Methods: In this study, oxygen consumption rate, ATP production, mitochondrial biosynthesis, glucose metabolism, and SIRT1-PGC-1α pathways in untreated and GS-treated different cells, fly, and mouse models were investigated. Results: GS pretreatment enhanced mitochondrial respiration capacity and ATP production in aerobic respiration-dominated cardiomyocytes and neurons, and promoted tricarboxylic acid metabolism in cardiomyocytes. Moreover, GS clearly enhanced NAD<sup>+</sup>-dependent SIRT1 activation to increase mitochondrial biosynthesis in cardiomyocytes and neurons, which was completely abrogated by nicotinamide. Importantly, ginsenoside monomers, such as Rg1, Re, Rf, Rb1, Rc, Rh1, Rb2, and Rb3, were found to activate SIRT1 and promote energy metabolism. Conclusion: This study may provide new insights into the extensive application of ginseng for cardiac and neurological protection in healthy subjects and patients.

      • KCI등재

        Colloidal synthesis of lead-free all-inorganic Cs3Sb2BrxI9−x nanocrystals

        Weijiang Gan,Sunqi Lou,Jing Wang 한국정보디스플레이학회 2019 Journal of information display Vol.20 No.4

        Environment-friendly lead-free perovskite nanocrystals (NCs) are highly desirable in terms of optoelectronic applications. Reported herein is the synthesis of perovskite-related Cs3Sb2Br9 NCs through a simple hot-injection approach. The morphologies and optical properties of NCs were controlled and optimized by varying the reaction temperature, time, and volume of surface ligands. Meanwhile, the Cs3Sb2Br9 NCs showed bandgap emission in the blue region centered at 470 nm, and 63nm full width at half maximum (FWHM). In addition, the Cs3Sb2Br9 NCs displayed high stability when immersed in a polar solvent like ethanol. It was also found that the bandgaps of the Cs3Sb2BrxI9−x NCs could be adjusted by regulating the composition of halogen.

      • KCI등재

        Systemic Inflammatory Biomarkers, Especially Fibrinogen to Albumin Ratio, Predict Prognosis in Patients with Pancreatic Cancer

        Lin Fang,Fei-Hu Yan,Chao Liu,Jing Chen,Dan Wang,Chun-Hui Zhang,Chang-Jie Lou,Jie Lian,Yang Yao,Bo-Jun Wang,Rui-Yang Li,Shu-Ling Han,Yi-Bing Bai,Jia-Ni Yang,Zhi-Wei Li,Yan-Qiao Zhang 대한암학회 2021 Cancer Research and Treatment Vol.53 No.1

        Purpose Systemic inflammatory response is a critical factor that promotes the initiation and metastasis of malignancies including pancreatic cancer (PC). This study was designed to determine and compare the prognostic value of neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR), and fibrinogen-to-albumin ratio (FAR) in resectable PC and locally advanced or metastatic PC. Materials and Methods Three hundred fifty-three patients with resectable PC and 807 patients with locally advan-ced or metastatic PC were recruited in this study. These patients were classified into a training set (n=758) and a validation set (n=402). Kaplan-Meier survival plots and Cox proportional hazards regression models were used to analyze prognosis. Results Overall survival (OS) was significantly better for patients with resectable PC with low preoperative PLR (p=0.048) and MLR (p=0.027). Low FAR, MLR, NLR (p < 0.001), and PLR (p=0.003) were significantly associated with decreased risk of death for locally advanced or metastatic PC patients. FAR (hazard ratio [HR], 1.522; 95% confidential interval [CI], 1.261 to 1.837; p < 0.001) and MLR (HR, 1.248; 95% CI, 1.017 to 1.532; p=0.034) were independent prognostic factors for locally advanced or metastatic PC. Conclusion The prognostic roles of FAR, MLR, NLR, and PLR in resectable PC and locally advanced or metastatic PC were different. FAR showed the most prognostic power in locally advanced or metastatic PC. Low FAR was positively correlated with OS in locally advanced or metastatic PC, which could be used to predict the prognosis.

      • KCI등재

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