21세기 한국사회 : 지식사회냐 정보사회냐

임현진,서이종 한국사회문화학회 2000 사회와 문화 Vol.12 No.-

This paper deals with the characteristics in the introduction of the concept of "knowledge society" and "information society" for Korean society at the 21st Century and with a usability of "knowledge-information society" as a conceptual synthesis. Chapter 2 shows that the concept of information society war introduced critically in the late 1980s and developed into an empirical research theme in the beginning of 1990s, with various conceptual variances, that the concept of knowledge society war introduced in the science of economy and business in the 1990s with various conceptual variances. Chapter 3/4 shows that information society concentrate on the information basis of knowlege transmission and storage, while knowledge society concentrate on the creation of knowledge as contents, that two concepts can be conceptually incorporated into "knowledge-based information society" or "information-based knowledge society", and finally into "knowledge-information society".

저작근 공간에서 재발된 치성각화낭

임수연,허경회,이원진,최현배,최순철 대한구강악안면방사선학회 2008 Imaging Science in Dentistry Vol.38 No.2

The odontogenic keratocyst (OKC) is a developmental odontogenic cyst typically occurring in the jaws. Since the first description of OKC was published in 1956, the lesion has been of particular interest because of its specific histopathologic features, high recurrence rate, and aggressive behavior. Recurrences most commonly arise within bone at the site of the original cyst. However, as lining cells may find their way into surrounding tissues either from implantation during surgery or from cortical perforation recurrences may arise at a distance from the original cyst. Here, we report a rare case of recurrent OKC which was first developed in mandible and recurred within the masticatory space.

심방조동과 특발성 심실빈맥 환자의 의식소실을 위해 사용한 Propofol 에 의한 정상 동성리듬으로의 전환

김태정,이춘수,이홍식,차영덕,정종권,임현경,이성근,한정욱,허이희 대한마취과학회 2002 Korean Journal of Anesthesiology Vol.42 No.2

감귤청과음료에 감귤 대용량 추출 플라보노이드 첨가에 따른 품질 변화

이지현(Ji Hyun Lee),임병선(Byoung Seon Lim),이선이(Sun Yi Lee),최영훈(Young Hun Choi),안현주(Hyun Joo An),이영재(Young Jae Lee),한창훈(Chang Hoon Han),홍현주(Hyun Ju Hong) 한국원예학회 2009 한국원예학회 학술발표요지 Vol.2009 No.10

Comparative study on metabolite level in tissue-specific human mesenchymal stem cells by an ultra-performance liquid chromatography quadrupole time of flight mass spectrometry

Lee, Seul Ji,Yi, TacGhee,Ahn, Soo Hyun,Lim, Dong Kyu,Kim, Si-na,Lee, Hyun-Joo,Cho, Yun-Kyoung,Lim, Jae-Yol,Sung, Jong-Hyuk,Yun, Jeong-Ho,Lim, Johan,Song, Sun U.,Kwon, Sung Won Elsevier 2018 Analytica Chimica Acta Vol.1024 No.-

<P><B>Abstract</B></P> <P>Mesenchymal stem cells (MSCs) are a promising therapeutic option for cell-based therapy due to their immunomodulatory and regenerative properties. They can be isolated from various adult tissues, including bone marrow, fat, dental tissue, and glandular tissue. Although they share common characteristics, little is known about the biological differences between MSC populations derived from different tissues. In this study, we used MS to compare the endogenous metabolite level in the human MSCs originating from the bone marrow, adipose tissue, periodontal ligaments, and salivary glands. Using an optimized metabolomics technique, we verified that human MSCs exhibit differences in the endogenous metabolite level depending on their source material, while the multivariate analysis showed that 5 lysophosphatidylcholines and 3 lysophosphatidylethanolamines can serve as markers for the discrimination between MSC sources and may be related to differences in their differentiation capacity. These results may significantly contribute to further mechanistic studies on the MSCs and provide novel insights into the properties and optimal usage of MSCs from different tissues.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Endogenous metabolite level of human mesenchymal stem cells (MSCs) was evaluated. </LI> <LI> MSCs from different tissue sources were compared. </LI> <LI> Metabolic markers to distinguish MSCs by source tissue were identified. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

<i>SlPMEI</i>, a pollen-specific gene in tomato

Kim, Woong Bom,Lim, Chan Ju,Jang, Hyun A.,Yi, So Young,Oh, Sang-Keun,Lee, Ha Yeon,Kim, Hyun A.,Park, Youn-Il,Kwon, Suk-Yoon Canadian Science Publishing 2014 Canadian journal of plant science. Revue canadienn Vol.94 No.1

<P> Kim, W. B., Lim, C. J., Jang, H. A., Yi, S. Y., Oh, S.-K., Lee, H. Y., Kim, H. A., Park, Y.-I. and Kwon, S.-Y. 2014. SlPMEI, a pollen-specific gene in tomato. Can. J. Plant Sci. 94: 73-83. Pectin is one of the main components of plant cell walls, and its biosynthesis is controlled by pectin methylesterase (PME). Pectin methylesterase inhibitors (PMEIs) are key regulators of PME. We report here the cloning and characterization of a novel Solanum lycopersicum L. PMEI gene, SlPMEI. RT-PCR studies of leaf, seed, fruit, flower, and flower organs confirmed that SlPMEI is expressed specifically in pollen. Promoter analysis of SlPMEI revealed pollen-specific cis-acting elements (pollen lat52 and g10). In addition, SlPMEI is expressed independently of abiotic stress, pathogen exposure, and growth stage in tomato, and a histochemical analysis of promoter activity revealed pollen-specific expression in both Arabidopsis and tomato. Under the microscope, we observed pollen-specific GUS expression in the stamen of transgenic tomato plant. These results indicate that the promoter of SlPMEI has strong pollen-specific activity, and could therefore be useful for development of industrially and agronomically important transgenic plants. </P>

Selection of affinity peptides for interference-free detection of cholera toxin

Lim, Jong Min,Heo, Nam Su,Oh, Seo Yeong,Ryu, Myung Yi,Seo, Jeong Hyun,Park, Tae Jung,Huh, Yun Suk,Park, Jong Pil Elsevier 2018 Biosensors & bioelectronics Vol.99 No.-

<P><B>Abstract</B></P> <P>Cholera toxin is a major virulent agent of <I>Vibrio cholerae,</I> and it can rapidly lead to severe dehydration, shock, causing death within hours without appropriate clinical treatments. In this study, we present a method wherein unique and short peptides that bind to cholera toxin subunit B (CTX-B) were selected through M13 phage display. Biopanning over recombinant CTX-B led to rapid screening of a unique peptide with an amino acid sequence of VQCRLGPPWCAK, and the phage-displayed peptides analyzed using ELISA, were found to show specific affinities towards CTX-B. To address the use of affinity peptides in development of the biosensor, sequences of newly selected peptides were modified and chemically synthesized to create a series of affinity peptides. Performance of the biosensor was studied using plasmonic-based optical techniques: localized surface plasmon resonance (LSPR) and surface-enhanced Raman scattering (SERS). The limit of detection (LOD) obtained by LSPR with 3σ-rule was 1.89ng/mL, while SERS had a LOD of 3.51pg/mL. In both cases, the sensitivity was much higher than the previously reported values, and our sensor system was specific towards actual CTX-B secreted from <I>V. cholera,</I> but not for CTX-AB<SUB>5</SUB>.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A sensitive and interference-free plasmonic-based peptide sensor was developed. </LI> <LI> The detection performance for cholera toxin was monitored by LSPR and SERS. </LI> <LI> The limit of detection obtained by LSPR was 1.89ng/mL, while SERS had 3.51pg/mL. </LI> </UL> </P>

Vascular and cardiac autonomic function and PM_2.5 constituents among the elderly: A longitudinal study

Lim, Youn-Hee,Bae, Hyun-Joo,Yi, Seung-Muk,Park, EunHa,Lee, Bo-Eun,Hong, Yun-Chul Elsevier 2017 Science of the Total Environment Vol.607 No.-

<P><B>Abstract</B></P> <P><B>Background</B></P> <P>Although epidemiologic studies have shown an association between the total mass of particulate matter <2.5μm in aerodynamic diameter (PM<SUB>2.5</SUB>) and cardiovascular disease, few studies have examined PM<SUB>2.5</SUB> constituents associated with vascular and cardiac autonomic dysfunction.</P> <P><B>Methods</B></P> <P>In this longitudinal study, we investigated the relationship between PM<SUB>2.5</SUB> constituents and blood pressure (BP), and markers of the autonomic nervous system. In 466 elderly subjects residing in communities in Seoul, Korea, we examined 16 constituents, seven sources, and total mass concentrations of PM<SUB>2.5</SUB>. We measured the BP, heart rate (HR), and indices of heart rate variability (HRV), such as the standard deviation of normal-to-normal intervals (SDNN), square root of the mean squared differences of successive NN intervals (rMSSD), and two frequency-domain variables (low frequency [LF] and high frequency [HF]). We used linear mixed effects models to assess the association of PM<SUB>2.5</SUB> constituents and sources with cardiovascular markers.</P> <P><B>Results</B></P> <P>BP, HR, and rMSSD were associated with concentration of total mass of PM<SUB>2.5</SUB>. For each increase of the interquartile range in PM<SUB>2.5</SUB> constituents, systolic and diastolic BP, and HR increased by 2.1–3.3mmHg, 1.2–2.3mmHg, and 1.2–1.9bpm, respectively, while the rMSSD, LF, and HF decreased by 8.1–9.3%, 16.6%, and 20.4%, respectively. Particularly, elemental carbon, sulfate, ammonium, lead, and strontium in the PM<SUB>2.5</SUB> constituents and emissions from oil combustion and incineration were associated with increased BP, HR, and decreased HRV.</P> <P><B>Conclusions</B></P> <P>Our results suggest an association between specific PM<SUB>2.5</SUB> constituents and vascular and cardiac autonomic functions. These findings may provide supportive evidence for developing a pollution reduction plan to prevent cardiovascular diseases.</P> <P><B>Highlights</B></P> <P> <UL> <LI> PM<SUB>2.5</SUB> constituents and vascular/cardiac autonomic function may have a relationship. </LI> <LI> Increases in blood pressure and heart rate were associated with PM<SUB>2.5</SUB> constituents. </LI> <LI> Decreased heart rate variability indices were associated with PM<SUB>2.5</SUB> constituents. </LI> <LI> Oil combustion and incineration emissions were associated with autonomic function. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

A case of multiple superficial basal cell carcinomas on the periauricular areas

( Hyun Yi Suh ),( Joo Yoon Bae ),( Hong Lim Kim ),( Kyung Ho Kim ),( Ji Young Ahn ),( Mi Youn Park ),( Jai Il Youn ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1

Superficial basal cell carcinoma (sBCC), a rare sub-type of basal cell carcinoma, can frequently occur in younger patients. sBCC is one of the sub-types that can preferentially develop on the trunk or limb, while the other subtypes of BCC are mainly found on the head and neck. Herein, we report a rare case for sBCC arising on the both periauricular areas. An 86-year-old woman presented with well-demarcated erythematous sclay patches around ears for 5~6 years. On physical examination, there was 1×2.5 cm sized erythematous sclay patch with black spots on the right postauricular area and 1×1.5 cm sized brownish and erythematous patch on the left preauricular area. A skin biopsy was performed both skin lesions. On histopathologic examination, tumor nests showed budding and peripherally palisading basaloid tumor cells in the epidermis. After initial diagnosis of sBCC, we recommended operation but the patient refused to operate. So we have considered her ages and have treated with cryotherapy. The skin lesions have been improved after three times cryotherapy. We report this impressive case involving multiple sBCC found on both periauricular, a rare location for sBCC.

Structural analysis of packing schemes for extracting hidden codes in mobile malware

Lim, Jongsu,Yi, Jeong Hyun SpringerOpen 2016 Eurasip Journal on Wireless Communications and Net Vol.2016 No.-

<P>In the Internet of Things service environment where all things are connected, mobile devices will become an extremely important medium linking together things with built-in heterogeneous communication functions. If a mobile device is exposed to hacking in this context, a security threat arises where all things linked to the device become targets of cyber hacking; therefore, greater emphasis will be placed on the demand for swift mobile malware detection and countermeasures. Such mobile malware applies advanced code-hiding schemes to ensure that the part of the code that executes malicious behavior is not detected by an anti-virus software. In order to detect mobile malware, we must first conduct structural analysis of their code-hiding schemes. In this paper, we analyze the structure of the two representative Android-based code-hiding tools, Bangcle and DexProtector, and then introduce a method and procedure for extracting the hidden original code. We also present experimental results of applying these tools on sample malicious codes.</P>