Stimulus-Responsive Azobenzene Supramolecules: Fibers, Gels, and Hollow Spheres

Lee, Sumi,Oh, Seungwhan,Lee, Joosub,Malpani, Yashwardhan,Jung, Young-Sik,Kang, Baotao,Lee, Jin Yong,Ozasa, Kazunari,Isoshima, Takashi,Lee, Sang Yun,Hara, Masahiko,Hashizume, Daisuke,Kim, Jong-Man American Chemical Society 2013 Langmuir Vol.29 No.19

<P>Novel, stimulus-responsive supramolecular structures in the form of fibers, gels, and spheres, derived from an azobenzene-containing benzenetricarboxamide derivative, are described. Self-assembly of tris(4-((<I>E</I>)-phenyldiazenyl)phenyl)benzene-1,3,5-tricarboxamide (<B>Azo-1</B>) in aqueous organic solvent systems results in solvent dependent generation of microfibers (aq DMSO), gels (aq DMF), and hollow spheres (aq THF). The results of a single crystal X-ray diffraction analysis of <B>Azo-1</B> (crystallized from a mixture of DMSO and H<SUB>2</SUB>O) reveal that it possesses supramolecular columnar packing along the <I>b</I> axis. Data obtained from FTIR analysis and density functional theory (DFT) calculation suggest that multiple hydrogen bonding modes exist in the <B>Azo-1</B> fibers. UV irradiation of the microfibers, formed in aq DMSO, causes complete melting while regeneration of new fibers occurs upon visible light irradiation. In addition to this photoinduced and reversible phase transition, the <B>Azo-1</B> supramolecules display a reversible, fiber-to-sphere morphological transition upon exposure to pure DMSO or aq THF. The role played by amide hydrogen bonds in the morphological changes occurring in <B>Azo-1</B> is demonstrated by the behavior of the analogous, ester-containing tris(4-((<I>E</I>)-phenyldiazenyl)phenyl)benzene-1,3,5-tricarboxylate (<B>Azo-2</B>) and by the hydrogen abstraction in the presence of fluoride anions.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/langd5/2013/langd5.2013.29.issue-19/la400159m/production/images/medium/la-2013-00159m_0013.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/la400159m'>ACS Electronic Supporting Info</A></P>

온라인 상담에 대한 상담자들의 경험과 인식 조사

한수미(Sumi Han),이상일(Sangil Lee),이경란(Kyungran Lee),이미옥(Miok Lee),이혜일(Hyeil Lee),김환(Hwan Kim) 한국산학기술학회 2021 한국산학기술학회논문지 Vol.22 No.11

본 연구의 목적은 상담자들의 온라인 상담 경험과 인식을 조사하고 미래 발전에 대한 제언을 도출하는 것이다. 상담자 93명을 대상으로 온라인 상담에 대한 설문을 실시했다. 설문의 내용은 ‘온라인 상담 경험 및 미래 전망’, ‘진행 및 구조화’, ‘비용’, ‘상담자 교육’과 관련된 영역으로 구성하였다. 조사 결과는 다음과 같다. 상담자들은 온라인 상담에 대해 대체로 긍정적인 인식을 가지고 있었다. 공공 플랫폼과 상업용 플랫폼을 중심으로 온라인 상담에 대한 참여가 이루어지고 있었다. 상담자들은 온라인 상담의 구조화된 진행이 중요하고, 사전계약, 동의서 작성 등이 상담에 도움이 된다고 응답했다. 다음으로, 온라인 상담은 10회기 미만으로 짧게 진행되어야 한다는 의견이 많았다. 그리고 온라인 상담이 내담자들의 요구와 인식의 부족으로 인해 대면 상담 보다 짧게 진행된다는 결과는 극복해야할 과제이다. 그리고 온라인 상담의 적절 비용과 교육에 대한 인식을 조사하였다. 마지막으로 온라인 상담 매뉴얼 개발, 윤리규정 확립, 대면 상담과의 연계, 온라인 상담 교육 및 훈련 강화라는 미래 발전을 위한 제언을 도출할 수 있었다. 본 연구의 결과가 온라인 상담의 발전을 위한 기초 자료로 활용될 것으로 기대한다. The purpose of this study was to investigate the online counseling experiences and perceptions of field counselors and derive suggestions for future development. A survey was conducted on online counseling among 93 counselors. The contents of the questionnaire consisted of areas related to "online counseling experience and future prospects", "process and structure", "cost" and "counselor"s education". Counselors had a positive perception of online counseling. Participation in online counseling was conducted mainly on public and commercial platforms. Counselors responded that the structured process of online counseling was important, and prior contracts and written consent were helpful for counseling. There were many opinions that the online consultation should be conducted briefly in less than 10 sessions. They also responded that online counseling was shorter than face-to-face counseling due to the lack of awareness and needs of clients, which was a challenge to be overcome. We investigated the appropriate cost of online counseling and perception of education. Finally, suggestions for future development, such as the development of an online counseling manual, the establishment of ethical regulations, face-to-face counseling and reinforcement of online counseling education, were summarized. The results of this study will be used as basic data for the development of online counseling.

Directed Assembly of High Molecular Weight Block Copolymers: Highly Ordered Line Patterns of Perpendicularly Oriented Lamellae with Large Periods

Kim, Eunhye,Ahn, Hyungju,Park, Sungmin,Lee, Hoyeon,Lee, Moongyu,Lee, Sumi,Kim, Taewoo,Kwak, Eun-Ae,Lee, Jun Han,Lei, Xie,Huh, June,Bang, Joona,Lee, Byeongdu,Ryu, Du Yeol American Chemical Society 2013 ACS NANO Vol.7 No.3

<P>The directed assembly of block copolymer nanostructures with large periods exceeding 100 nm remains challenging because the translational ordering of long-chained block copolymer is hindered by its very low chain mobility. Using a solvent-vapor annealing process with a neutral solvent, which was sequentially combined with a thermal annealing process, we demonstrate the rapid evolution of a perpendicularly oriented lamellar morphology in high molecular weight block copolymer films on neutral substrate. The synergy with the topographically patterned substrate facilitated unidirectionally structural development of ultrahigh molecular weight block copolymer thin filmseven for the structures with a large period of 200 nmleading to perfectly guided, parallel, and highly ordered line-arrays of perpendicularly oriented lamellae in the trenched confinement. This breakthrough strategy, which is applicable to nanolithographic pattern transfer to target substrates, can be a simple and efficient route to satisfy the demand for block copolymer assemblies with larger feature sizes on hundreds of nanometers scale.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancac3/2013/ancac3.2013.7.issue-3/nn3051264/production/images/medium/nn-2012-051264_0007.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nn3051264'>ACS Electronic Supporting Info</A></P>

L - Ascorbic Acid 가 Guinea Pig 에서 혈장 지질과산화값 , Prostaglandin 생합성 , 광용혈 , Superoxide Dismutase 및 Catalase 활성에 미치는 영향

이정원,이태녕,모수미,이진호,이대형,박수남,이보경 ( Joung Won Lee,Tae Young Lee,Sumi Mo,Jin Ho Lee,Dae Hyung Lee,Soo Nam Park,Bo Kyung Lee ) 생화학분자생물학회 1987 BMB Reports Vol.20 No.4

Three levels of L-ascorbic acid(AsA) were orally given to 20 male Hartley guinea pigs weighing average 428 g for five weeks. AsA level was 0, 2.5, and 100 mg per 100 g body weight per day in the deficient, the adequate, and the excess group, respectively. Plasma lipid peroxide value(TBA value) of deficient was increased to the highest among the three groups and both the adequate and the excess groups exhibited the lower TBA values, suggesting the antioxidant action of AsA. In the excess of AsA, plasma TBA value was greatly lowered one day after the feeding, but TBA value after 5 weeks was elevated comparable to that of the adequate. Aspirin administrating experiment suggested that this elevation was due to increased. production of prostaglandin(PG) endoperoxides induced by excess AsA. Thus it could be concluded that excess AsA actually inhibited the tissue lipid peroxidation in vivo. The activities of both superoxide dismutase(SOD) and catalase in erythrocytes demonstrated the elevations in the deficient comparing with the auequate, but not any significant variations in the excess. SOD activities were correlated with TBA value in liver (r = .324) and with percent hemolysis in erythrocytes (r = .323). Photohemolysis of erythrocyte was increased not only in the AsA deficient but also in the excess comparing with the adequate. A new finding that the large excess administration of AsA in guinea pig demonstrated a significant stimulation of PG endoperoxide biosynthesis, would suggest an important biochemical implication on vitamin C as an activator of phospholipase A₂ and/or PG endoperoxide synthetase. The stimulation of PG biosynthesis might be associated with the enhanced photohemolysis, and this problem needs to be further investigated.

Communication—Highly Efficient Electroenzymatic NADH Regeneration by an Electron-Relay Flavoenzyme

Lee, Sumi,Choe, Hyunjun,Cho, Dae Haeng,Yoon, Sung Ho,Won, Keehoon,Kim, Yong Hwan The Electrochemical Society 2016 Journal of the Electrochemical Society Vol.163 No.5

<P>Efficient cofactor regeneration is essential for the utilization of many oxidoreductases. Herein, the beta-subunit of formate dehydrogenase 1 from Methylobacterium extorquens AM1 (MeFDH1-beta) was employed as a novel electroactive biocatalyst for electroenzymatic NADH regeneration for the first time. MeFDH1-beta showed much better properties in both catalytic activity (a turnover frequency of 3,600 hr(-1)) and current efficiency (ca. 98%) than a conventional rhodium (III)-based chemical catalyst (M = [Cp*Rh(bpy)H2O](2+), Cp* = C5Me5, bpy = 2,2'-bipyridine) and a traditional biocatalyst (diaphorase). (C) 2016 The Electrochemical Society. All rights reserved.</P>

Review of “Representing Korean Buddhism: Toward a Transnational Understanding of the Field of Korean Buddhist Studies”

Sumi LEE The Academy of Korean Studies 2021 Korea Journal Vol.61 No.3

Immunohistochemical evidence for the over-expression of Glutathione peroxidase 3 in clear cell type ovarian adenocarcinoma.

Lee, Hee Joong,Do, Jin Hwan,Bae, Sumi,Yang, Sanghwa,Zhang, Xianglon,Lee, Ahwon,Choi, Young Jin,Park, Dong Choon,Ahn, Woong Shick Science and Technology Letters 2011 MEDICAL ONCOLOGY -NORTHWOOD THEN BASINGSTOKE THEN Vol.28 No.1

<P>Glutathione peroxidase 3 (GPX3) is a member of glutathione peroxidase family, exerting one of the most important cellular defense mechanisms against stress signals, including oxidative damage. In this study, the expression of GPX3 mRNA and protein was analyzed for ovarian cancer tissues to test its applicability as a biomarker that can distinguish the four major histologic types of epithelial ovarian cancer. A public microarray dataset containing 99 ovarian cancer and 4 normal ovary samples was downloaded, and GPX3 mRNA expression was analyzed. The expression of GPX3 protein was measured by immunohistochemical staining in 40 epithelial ovarian cancer tissues, 10 for each of the serous, endometrioid, mucinous, and clear cell type. Histoscores were made from the immunohistostaining, and analysis of variance (ANOVA) was performed to quantitate the differences in protein level. Analysis of genomic dataset confirms a GPX3 overexpression in clear cell type ovarian adenocarcinoma compared with normal ovary and 3 other subtypes of epithelial ovarian cancer at mRNA level. GPX3 also shows the highest average antibody staining intensities in clear cell type ovarian adenocarcinomas over the other 3 types in immunostaining on tissue arrays. This is the first validation of GPX3 as a clear cell type-specific biomarker in ovarian cancer patients' tissues by immunostaining. GPX3 may serve as an important molecular marker for the diagnosis and molecular understanding of clear cell carcinoma of the ovary.</P>

베트남인 교사와 한국인 교사의 한국어교육 경험에 대한 연구

( Lee Sumi ) 부산대학교 과학교육연구소 2019 교사교육연구 Vol.58 No.3

이 연구는 한국인 교사와 베트남인 교사가 베트남에서 한국어를 가르치면서 겪는 경험에 대해 기술한 것이다. 연구자는 1997년부터 2000년까지 베트남 하노이국립인문사회대학교에서 한국어를 가르친 바 있다. 그때의 베트남 현장은 한국인 교사만으로 한국어를 가르쳤다. 그러나 한국어를 전공한 베트남인 교사가 배출되면서 베트남은 한국인 교사와 베트남인 교사가 같은 현장에서 한국어를 가르치고 있다. 이 연구는 이들이 같은 현장에서 한국어를 가르치면서 어떠한 경험을 하는지를 기술하는 것이 일차적 목표였다. 이러한 연구 목적에 도달하기 위해 한국인 교사와 베트남인 교사들이 들려준 이야기를 활용하는 내러티브 연구 방법을 활용하였다. 이 연구를 통해 베트남인 교사와 한국인 교사 모두는 현장에서 한국어 학습자를 만나는 기쁨을 공유하고 있었다. 이들은 가르치는 현장을 좋아했다. 그러나 한국인 교사는 스스로 주인에서 벗어나 외부인으로 자각하는 시점이 있고, 베트남인 교사들은 한국이 교사를 손님으로 대우한다고 했다. 이러한 인식의 원인은 이들이 한국어 교사를 직업과 봉사 사이의 어디쯤으로 생각하는 것과 다수가 사용하는 베트남어를 모르는 한국인 교사들의 언어 문제가 결정적인 원인으로 보였다. 그럼에도 이들의 이야기를 통해 한국인 교사와 베트남인 교사가 서로가 공생의 관계라는 이해가 공유된다는 점에서 한국어교육이 발전할 수 있을 것이라는 가능성을 감지할 수 있었다. 이 연구는 베트남 현장에서 한국어를 가르치는 두 집단, 즉 한국인 교사와 베트남인 교사의 한국어교육 경험을 통해 이들의 현장을 좀 더 이해할 수 있었다는 점에서 연구의 의의를 찾고 싶다. This study described what Korean language teachers and Vietnamese teachers experience when they teach Korean in Vietnam. The researcher has taught Korean in Vietnam National University, Hanoi, University of Social Sciences and Humanities from 1997 to 2000. Only Korean teachers taught Korean language at the time but Korean teacher and Vietnamese teacher are teaching Korean language in the same field as Vietnamese teachers who majored in Korean have been produced. The primary objective of this study was to describe what they experience while they teach Korean in the same field. Through this study, it was identified that both Vietnamese teachers and Korean teachers were sharing the pleasure of meeting Korean language learners at the scene. They liked the field of teaching. However, Korean teachers had a viewpoint of perceiving themselves as outsiders and Vietnamese teachers stated that Korea treats teachers as guests. Language problem of Korean teachers who do not know Vietnamese that the majority of people use seemed as a decisive factor, but the inherent limitation of Koreans not residing in Vietnam continuously seems as the likely cause. Nevertheless, they were able to sense the possibility that they can develop through a mutual understanding. The significance of this study is to provide a better understanding of the education field through the Korean language educational experience of the two groups who teach Korean language in Vietnam as Korean teachers and Vietnamese teachers.

Photoinduced Fluorescence Patterning with a t-Boc Protected Dihydroxyphenylene Derivative

Sumi Lee,Tae-Young Ahn,Sangjun Kim,Young-Sik Jung,김종만 대한화학회 2010 Bulletin of the Korean Chemical Society Vol.31 No.10

Effect of some lichen extracts on insecticidal activities and development the larvae of Aedes albopictus

Sumi Lee,Byungsik Shin,Minhyo Kang,Jiyoung Hong,Dasol Bae,Yaeji Yoon,Byungmin Song 한국응용곤충학회 2018 한국응용곤충학회 학술대회논문집 Vol.2018 No.04

지의류 추출물이 흰줄숲모기(Aedes albopictus)에 대하여 살충활성 및 생장 억제에 미치는 영향을 조사하였다. 2종의 지의류의 메탄올 추출물이 흰줄숲모기 3령 유충에 미치는 치사농도, 사충수, 생장억제를 알아보기 위한 실험을 진행한 결과Parmelia sp.엽상체 추출물경우 LC50농도는 0.13%로 나타났으며 Porpidia albocaerulescens의 LC50농 도는 0.45%로 나타나 Parmelia sp.의 추출물이 더 높은 살충활성을 보였다. 24h, 48h, 72h의 노출시간 따른 농도별 사충 수를 조사한 결과, 전반적으로 지의류의 메탄올 추출물이 고농도일수록, 노출시간이 길어질수록 유충의 사충 수는 증가하였다. Parmelia sp. 엽상체의 추출물에서 사육한 유충의 경우 용화시간은 대조군보다 지연되었고, 추출물의 농도가 높을수록 더 많은 시간이 지연된 것으로 보아 지의류 추출물이 흰줄숲모기 유충의 생장을 억제하는 효과가 있음을 확인하였다.