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이소정 ( So Jung Lee ),권소망 ( So Mang Kwon ),마강희 ( Kang Hui Ma ),손소희 ( So Hee Son ),정철의 ( Chul Eui Jung ) 한국토양동물학회 2014 한국토양동물학회지 Vol.18 No.1
Greater attentions are paid to the insect industry (insect farming) especially for the economic, sustainable solution to feed the growing world population following the issue of FAO report of edible forest insect in May 2013. In Korea, legislation of insect industry law provides the funding for the research and development on commercialization of insect farming and processing. Korea has a long history of entomophagy but most for the medicinal purpose not for the dietary needs. This reports the importance of the commercialization of edible insects, current status of R&D and marketing in Europe and Korea, and its possibility of feeding global human population as well as income generation. Also, we suggested some tactics to improve the friendly awareness of entomophagy otherwise easily repelled.
RAW264.7세포에서 식물 추출물 6종의 Nitric Oxide 생성 억제 효과
So Hui Jeong,Nam Woo Kwon,Jae Yeon Kim,Yong Beom Cho,Seong Sub Ku,Moon Soon Lee 한국약용작물학회 2016 한국약용작물학술대회 발표집 Vol.2016 No.10
Background : As a part of ongoing research to elucidate and characterize anti-inflammatory nutraceuticals, six kinds of plant extracts (aerial part of Nepeta cataria, leaves of Lonicera maackii, leaves of Platycarya strobilacea, flower of Fagopyrum dibotrys, flowers and fruits of Solanum nigrum, stem of Physostegia virginiana) were tested for their ability to suppress inflammation. The anti-inflammatory has been studied in lipopolysaccharide (LPS)-stimulated RAW264.7 cells which cells synthesized nitric oxide (NO) from L-arginine by nitric oxide synthase (NOS). In this study, NO synthesis inhibitory activity of six kinds of plant extracts on LPS-stimulated RAW 264.7 mouse macrophages was evaluated. Methods and Results : Six kinds of plant extracts were parceled out from RDA (Rural Development Administration). RAW 264.7 cells (1.5×105 cells/well) were seeded onto 96-well plates with DMEM media containing 10% FBS and 1% antibiotics. The cells were pretreated with the extracts and LPS-stimulated cells for 24 h. Cellular NO production was stimulated by adding 1 μg/mL of LPS. After incubation, Griess reagent was used to determine NO production. Absorbance was measured at 520 nm by microplate reader. NO synthesis inhibitory activity potential of these extracts was evaluated by assessing NO production by LPS-stimulated RAW 264.7 cells in the presence. As a result, inhibition rate of NO production was about 40% of L. maackii, 33% of F. dibotrys, 23% of P. strobilacea and 17% of P. virginiana. Meanwhile, there was no significant results in aerial part of N. cataria and flowers and fruits of S. nigrum. Conclusion : From the above results, we be able to confirm that leaves of L. maackii and flower of F. dibotrys appeared dose-dependent NO synthesis inhibitory activity and leaves of P. strobilacea appeared NO synthesis inhibitory activity in low-concentration. As screening NO synthesis inhibition of six extracts, they may be a good candidate for delaying the progression of human inflammatory diseases and warrants further studies.
Synthesis and Characterization of New Anthracene-Based Blue Host Material
So, Ki-Ho,Park, Hyun-Tae,Shin, Sung-Chul,Lee, Sang-Gyeong,Lee, Dong-Hui,Lee, Kyeong-Hoon,Oh, Hyeong-Yun,Kwon, Soon-Ki,Kim, Yun-Hi Korean Chemical Society 2009 Bulletin of the Korean Chemical Society Vol.30 No.7
We designed new anthracene-based host material to increase color purity as well as device efficiency. The new blue host, 9,10-bis(2,4-dimethylphenyl)anthracene (BDA), has highly twisted structure and wide band gap due to ortho interaction between anthracene and introduced 2,4-dimethylphenyl substituents. BDA exhibited deep blue fluorescence in solution (${\lambda}_{max}$ = 410 nm) and in solid state (${\lambda}_{max}$ = 429 nm), respectively, with the wide optical band gap (E = 3.12 eV). Blue-light-emitting OLEDs using obtained host and 2% Flu-DPAN as emitter showed 8 cd/A of high efficiency as well as high color purity [CIE coordinates = (0.15, 015)].
Synthesis of a Low-Bandgap Fluorinated Donor–Acceptor Copolymer and Its Optoelectronic Application
Yun, Hui-Jun,Hwang, Moon Chan,Park, So Min,Kim, Ran,Chung, Dae Sung,Kim, Yun-Hi,Kwon, Soon-Ki American Chemical Society 2013 ACS APPLIED MATERIALS & INTERFACES Vol.5 No.13
<P>We demonstrate the synthesis of a new copolymer which is composed of dialkyl thienylated benzodithiophene and perfluororalkyl-carbonyl thienothiophene (DTBDT-TTFO) and the characterization of its optoelectronic properties. The introduction of thienyl groups enabled the extended delocalization of π electrons in the DTBDT-TTFO backbone and efficient intermolecular charge transport as proved by the fairly high field effect mobility of 0.02 cm<SUP>2</SUP>/(V s). The introduction of perfluororalkyl-carbonyl side chains resulted in a significant red-shift of DTBDT-TTFO in the absorption spectra and a decrease in the HOMO and LUMO levels. The resulting energy levels of DTBDT-TTFO were not satisfactory for solar cell applications, especially in terms of charge separation at the polymer/PCBM interfaces. Rather, the DTBDT-TTFO showed better energy level matching with the colloidal nanocrystals (NCs) of CdSe. A photodetector based on the bulkheterojunction of DTBDT-TTFO and CdSe NCs with coplanar device geometry resulted in a high photoconductive gain (responsivity higher than 1A/W under a low operating voltage of 1 V), possibly arising from electron trapping at CdSe NCs such that the hole can travel along the detector and its surrounding circuit. More importantly, the photodetector revealed a time constant of a few hundreds of microseconds, which means that the response speed of the photodetector is fast enough for lag-free imaging applications.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/aamick/2013/aamick.2013.5.issue-13/am4007935/production/images/medium/am-2013-007935_0010.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/am4007935'>ACS Electronic Supporting Info</A></P>
( Eun Hui Sim ),( Jung Hyun Kwon ),( Se Young Kim ),( Seung Min Jung ),( Lee So Maeng ),( Jeong Won Jang ),( Kyu Won Chung ) 대한간학회 2012 Clinical and Molecular Hepatology(대한간학회지) Vol.18 No.4
The most common finding related to nonalcoholic steatohepatitis is obesity, but a status of severe malnutrition can also induce the steatohepatitis. The authors report a rare case of steatohepatitis leading to hepatic decompensation caused by malnutrition after pancreaticoduodenectomy. A 68-year-old female patient who had been previously diagnosed with pancreatic cancer and had undergone pancreaticoduodenectomy 5 months previously presented with abdominal distension. Routine CT performed 3 months after the surgery revealed severe fatty liver without evidence of tumor recurrence. After undergoing pancreaticoduodenectomy her food intake had reduced, and as a result she had lost 7 kg of body weight over 2 months. At this admission, CT revealed moderate amounts of ascites without tumor recurrence. Furthermore, her albumin and lipid profile levels were markedly decreased, and she had a flapping tremor and slurred speech suggestive of hepatic encephalopathy. Her liver biopsy findings were consistent with steatohepatitis and disclosed macrovesicular steatosis without definite fibrosis. After careful nutritional control, her symptoms disappeared and her laboratory findings improved. (Clin Mol Hepatol 2012;18:404-410)
Diagnostic Tools for Alzheimer’s Disease: A Narrative Review Based on Our Own Research Experience
Park So-Hee,Kwon Kyoung Ja,Kim Min Young,Kim Jae-Hun,Moon Won-Jin,Ryu Hui Jin,Jang Jae Won,Moon Yeonsil 대한치매학회 2023 Dementia and Neurocognitive Disorders Vol.22 No.1
Alzheimer’s disease (AD), one of the most representative neurodegenerative diseases, has diverse neurobiological and pathophysiological mechanisms. Treatment strategies targeting a single mechanism have repeated faced failures because the mechanism of neuronal cell death is very complex that is not fully understood yet. Since complex mechanisms exist to explain AD, a variety of diagnostic biomarkers for diagnosing AD are required. Moreover, standardized evaluations for comprehensive diagnosis using neuropsychological, imaging, and laboratory tools are needed. In this review, we summarize the latest clinical, neuropsychological, imaging, and laboratory evaluations to diagnose patients with AD based on our own experience in conducting a prospective study.