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Joo-Young Park,Kangsun Lee,Doo Ryeon Chung 대한내과학회 2022 The Korean Journal of Internal Medicine Vol.37 No.6
Background/Aims: The coronavirus disease 2019 (COVID-19) pandemic has accelerated digital transformation (DT). We investigated the trend of the public interest in technologies regarding the DT and Koreans’ experiences and their perceptions of the future impact of these technologies. Methods: Using Google Trends, the relative search volume (RSV) for topics including “coronavirus,” “artificial intelligence,” “cloud,” “big data,” and “metaverse” were retrieved for the period from January 2020 to January 2022. A survey was conducted to assess the population’s knowledge, experience, and perceptions regarding the DT. Results: The RSV for “metaverse” showed an increasing trend, in contrast to those for “cloud,” “big data,” and “coronavirus.” The RSVs for DT-related keywords had a negative correlation with the number of new weekly COVID-19 cases. In our survey, 78.1% responded that the positive impact of the DT on future lives would outweigh the negative impact. The predictors for this positive perception included experiences with the metaverse (4.0-fold) and virtual reality (VR)/augmented reality (AR) education (3.8-fold). Respondents predicted that the biggest change would occur in the healthcare sector after transportation/ communication. Conclusions: Koreans’ search interest for “metaverse” showed an increasing trend during the COVID-19 pandemic. Koreans believe that DT will bring about big changes in the healthcare sector. Most of the survey respondents have a positive outlook about the impact of DT on future life, and the predictors for this positive perception include the experiences with the metaverse or VR/AR education. Healthcare professionals need to accelerate the adoption of DT in clinical practice, education and training.
AI 반도체 제품 개발 동향 및 기술 발전 방향 : 데이터센터용 성능 비교를 중심으로
박종현(Jong-Hyun Park),송근혜(Geunhye Song),설성호(Seong-Ho Seol),주보라(Bora Joo),신강선(Kangsun Shin) 대한전자공학회 2023 대한전자공학회 학술대회 Vol.2023 No.6
The Korean government recently suggested a project for developing world-class level AI semiconductor products for data centers. This paper investigated the development trends for both domestic and foreign AI semiconductor products for data centers and compared the products’ performance. In detail, we compared the performance of ten products, decoupling AI training and inference. The performance comparison included comparing (1) measures―operating performance and power consumption―in dual axis and (2) AI semiconductor product’s operating performance in relation to maximum power consumption according to the release date. In conclusion, we outlined domestic and foreign AI semiconductor products development trends and suggested some implications and directions for future development; Korean AI semiconductor industry needs to be competitive in AI training, facing a rapidly growing global AI technology such as generative AI.
국방 재사용 자원의 클라우드 저장소를 위한 계층형 보호 시스템
박찬종,한승철,이강선,Park, Chanjong,Han, Seungchul,Lee, Kangsun 한국시뮬레이션학회 2015 한국시뮬레이션학회 논문지 Vol.24 No.3
국방 M&S(Modeling & Simulation) 분야는 컴퓨터상에 모의 전장 환경 및 무기 모델을 구축하고 다양한 시나리오에 의해 시뮬레이션을 수행하여 무기체계의 효과도를 분석하는 현실적인 수단으로 이용되고 있다. 그러나, 무기체계의 구조 및 행위가 복잡해짐에 따라 이를 시뮬레이션 모델로 만드는 과정이 어려워지고 있다. 모델 재사용 저장소는 시뮬레이션 모델 구축에 필요한 비용을 절감하기 위해 기존에 개발 및 검증된 모델을 저장하고 있다. 그러나 기존의 재사용 저장소들은 특정 플랫폼 및 환경에서만 운용되어 사용자 층에 제한이 있으며, 보안 및 무중단 서비스를 위한 메커니즘이 미흡하여 무기체계 모델과 같은 보안 및 신뢰성이 필요한 모델을 저장하기에는 한계가 있다. 본 논문에서는 무기체계 모델의 재사용을 장려하기 위한 클라우드 저장소인 W-Cloud (Weapon Cloud)를 구축하여 다양한 플랫폼 및 환경에서 활용될 수 있도록 하였다. 또한, 계층형 정보보호 및 기밀성 보장을 통해 무기 모델의 재사용 과정에서 생길 수 있는 보안상의 문제를 효과적으로 해결할 수 있도록 하였다. Defense M&S (Modeling & Simulation) is utilized as a realistic method to analyze MOE (Measure of Effectiveness) of weapon systems by modeling weapons and their operational environment on the computer, and simulating them under various war scenarios. As weapon systems become complex in their structure and dynamics, model engineering are experiencing difficulties to construct simulation models on a computer. A model repository helps model developers to save model development time and cost by systematically storing predefined and already validated models. However, most repositories for Defense M&Shave not been successful partly due to limited accessability, vulnerability to security threats, and low level of dependability. In this paper, we propose W-Cloud (Weapon Cloud), a cloud model repository for reusing predefined weapon models. Clients can access W-Cloud on any platforms and various devices, yet security and confidentiality concerns are guaranteed by employing multi-tier information protection mechanism.
Accomplishment of canine cloning through in vitro matured oocytes: a pioneering milestone
Kuk Bin Ji,Kangsun Park,Dongern Kim,Eunyoung Kim,Tae Young Kil,김민규 한국축산학회 2024 한국축산학회지 Vol.66 No.3
The in vitro maturation (IVM) rate of canine oocytes remains low compared to other mammals due to their unique reproductive characteristics. This study aimed to explore the effect of hormone supplementation during the IVM of canine immature oocytes on nuclear maturation and subsequently assess its potential application in canine somatic cell nuclear transfer (SCNT). Immature oocytes were collected and cultured in an IVM medium supplemented with hormones (follicle-stimulating hormone [FSH] and progesterone [P4]) or without hormones (control) for 24 hours. The maturation rates of oocytes in the hormone-treated group (94.92 ± 3.15%) were significantly higher than those in the control group (61.01 ± 4.23%). Both in vitro and in vivo matured oocytes underwent NT to evaluate their utility, and the fusion rates were higher in the in vitro matured group than those in the vivo matured group, not significant between in vivo and in vitro matured group (73.28% and 82.35%, respectively). As a result, 14 fused embryos from the in vitro matured group were transferred into two surrogates, with one surrogate achieving a successful pregnancy and delivering four puppies. Whereas in the in vivo matured group, 85 fused embryos were transferred to 8 surrogate mothers, leading to three surrogates becoming pregnant and delivering one, four, and two puppies. The pregnancy rates were not significant between both groups (50% and 37.50%), but the number of offspring exhibited a significant difference (28.57% and 8.23%). In conclusion, we achieved a remarkable milestone by successfully producing cloned puppies using in vitro matured oocytes, underscoring the feasibility of canine cloning from in vitro recovered oocytes. It is important to note that this study focused only on immature oocytes after ovulation and only during the estrus stage. Further research targeting other stages of the estrous cycle could potentially enhance canine cloning efficiency.
Han, Yong Duk,Kim, Ka Ram,Park, Yoo Min,Song, Seung Yeon,Yang, Yong Ju,Lee, Kangsun,Ku, Yunhee,Yoon, Hyun C. Elsevier 2017 Materials Science and Engineering C Vol. No.
<P><B>Abstract</B></P> <P>According to recent increases in public healthcare costs associated with diabetes mellitus, the development of new glycemic monitoring techniques based on the biosensing of glycated hemoglobin A1c (HbA<SUB>1c</SUB>), a promising long-term glycemic biomarker, has become a major challenge. In the development of HbA<SUB>1c</SUB> biosensors for point-of-care applications, the selection of an effective biorecognition layer that provides a high reaction yield and specificity toward HbA<SUB>1c</SUB> is regarded as the most significant issue. To address this, we developed a novel HbA<SUB>1c</SUB> biosensing interfacial material by the integration of boronate hydrogel with glass fiber membrane. In the present study, a new boronate-functionalized hydrogel was designed and spatio-selectively photopolymerized on a hydrophilic glass fiber membrane by using N-hydroxyethyl acrylamide, 3-(acrylamido)phenylboronic acid, and bis(<I>N</I>,<I>N</I>′-methylene-bis-acrylamide). Using this approach, the boronic acid group, which specifically recognizes the cis-diol residue of glucose on the HbA<SUB>1c</SUB> molecule, can be three-dimensionally coated on the surface of the glass fiber network with a high density. Because this network structure of boronate hydrogel-grafted fibers enables capillary-driven fluid control, facile HbA<SUB>1c</SUB> biosensing in a lateral flow assay concept could be accomplished. On the proposed HbA<SUB>1c</SUB> biosensing interface, various concentrations of HbA<SUB>1c</SUB> (5–15%) in blood-originated samples were sensitively measured by a colorimetric assay using horseradish peroxidase, a glycoenzyme can generate chromogenic signal after the competitive binding against HbA<SUB>1c</SUB> to the boronic acid residues. Based on the demonstrated advantages of boronate hydrogel-modified membrane including high analytical performance, easy operation, and cost-effectiveness, we expect that the proposed biorecognition interfacial material can be applied not only to point-of-care HbA<SUB>1c</SUB> biosensors, but also to the quantitative analysis of other glycoprotein biomarkers.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Boronic acid (BA) hydrogel was synthesized for HbA<SUB>1c</SUB> biosensing. </LI> <LI> BA hydrogel was patterned on the glass fiber membrane via photo-crosslinking. </LI> <LI> HbA<SUB>1c</SUB> and peroxidase were competitively bound to BA hydrogel-modified membrane. </LI> <LI> HbA<SUB>1c</SUB> could be efficiently quantified by peroxidase-based chromogenic reaction. </LI> <LI> HbA<SUB>1c</SUB> in the whole blood sample was determined within a range of 4.6–15.2%. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>