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      • 사회환경교육의 교육과정 표준화 모형 및 통합프로그램 개발연구

        박석순,최돈형,성효현,허명,강명희,이숙임,남상준 이화여자대학교 환경문제연구소 1998 이화환경연구 Vol.2 No.-

        This paper presents the development of standardized modules and an integrated program which will be used for social environmental education. The study objectives are to develop modules which are based on various environmental topics, to relate the regional environmental topics to the educational modules and program, and to include the demand of students in the modules and program. Literature and questionary surveys, as well as, module development method were utilized as research tools. The titles of developed modules are "The Green Plant Earth," "Unexpected Resources: Save Resources and Recycle", "Water as the Mother of All Lives", "The Blue Sky with Clean Air", and "Soil as the Home of All Living and Non-living Things". It is hoped that the developed modules and program are utilized as course materials and curriculum for social environmental education in various educational institutes. The study results will be materialized as multimedia in near futher.

      • 소아에서 Fogarty 카테터를 이용한 일측폐 환기 마취 경험

        유수봉,강효석,임지훈,김두식,류시정 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.3

        Thoracic surgery may be greatly facilitated by causing selective atelectasis of the lung being operated on (one-lung ventilation anesthesia). But the tube used for one-lung ventilation is greater outer diameter than conventional endotracheal tube when compare to each other with same inner diameter, so in some young children it is impossible to one-lung ventilation using double lumen tube or bronchial blocker tube because of narrow vocal cord. We performed one lung ventilation anesthesia using conventional endotracheal tube and Fogarty catheter as a bronchial blocker in 11-year old women who received lung biopsy surgery and left lower lobectomy.

      • KCI등재

        스커트 3D 모델의 기하학적 생성 방법

        최우혁,최창석,김효숙,강인애 한국의류학회 2003 한국의류학회지 Vol.27 No.7

        This paper proposes a geometrical method for generating and draping the skirt 3D models. The method constructs a 3D basic skirt model using a truncated elliptical cone and generates the various skirt 3D models by controlling the elliptical cone. The B-Spline approximates the 3D drapes which change variously according to the angles and the textiles of the skirts. The mapping sources consist of the textile textures and the skirt 2D model. The 2D models are obtained by mapping the 3D skirt models to the 2D plane. The mapping sources allow us to map the textiles to the 3D skirts. We make the real skirts for the 6 kinds of angles and textiles, and investigate the data of their drape appearances. The investigated data are applied to the virtual skirts. Appearances of the virtual skirts are similar to those of the real.

      • 韓牛 末梢血液 淋巴球의 在來山羊 赤血球 Rosette形成

        宋憙鍾,金鍾冕,姜明大,蔡孝錫 全北大學校 附設 畜産開發硏究所 1988 畜産開發硏究報告 Vol.2 No.-

        In order to enumerate the T lymphocytes in bovine peripheral blood lymphocytes(PBL) by E rosette assay, KGRBC were treated with various concentration of 2-aminoethylisothiouronium bromide hydrobromide(AET) and dextran(Dex), singte or combination. The PBL from 10 clinically normal Korean native cattle were formed as low percentage of spontaneous E rosette(6.7±2.4%) in control group, whereas KGRBC treated with 0.1M AET for 20 minutes and 8%Dex were formed as 37.3±2.7% and 45.1±2.1%, respectively. And the synergistic effects were noted no less than 66.5±5.6% when the KGRBC treated with 0.1M AET and 8% Dex subsequently. These results suggest that the KGRBC would be a useful agent for the enumeration of T tymphocytes by E rosette assay in bovine PBI.

      • 소규모지역에서의 지가 및 인구 분포 특성에 관한 연구 : 부산광역시 북구를 대상으로

        이성호,조병렬,강석효 釜山大學校 都市問題硏究所 2003 都市硏究報 Vol.15 No.-

        It is important to inquiry into the characteristics of several features which are components of a city in studying. However, it was impossible to analyze the existing inquiries in micro because of the limitation of information. Especially, there were not any examples in small scale area and it was very hard to guess the characteristics of the area using the existing information and systems. I presented micro analysis method in small scale area. It was based on not only the production method of land cost and the density of population using GIS is more advanced than existing, but also compared analysis of each feathers through the Grid analysis.

      • 개선된 다출력 동적 CMOS 설계 방식을 이용한 고성능 32 비트 CLA가산기 설계 및 구현

        송근호,방만식,서정훈,한석붕,이효상,김강철 慶尙大學校生産技術硏究所 1997 生産技術硏究所論文集 Vol.13 No.-

        In this paper, we designed, implemented and evaluated 32-bit CLA adder with the ENMODL(enhanced NORA Multiple Output Domino Logic) logic style which is new dynamic CMOS logic. The circuit is implemented using 0.8㎛ CMOS double-metal process technology. It operates stably and the addition time is less 3.9 ns. The ENMODL logic style can improve the performance in the high-speed computing circuits depending on the degree of recurrence.

      • 乳房炎 乳汁에서 分離된 原因菌의 抗菌劑 感受性

        崔民淳,金鍾冕,趙正坤,蔡孝錫,姜明大,宋熹鍾 全北大學校 附設 畜産開發硏究所 1987 畜産開發硏究報告 Vol.1 No.-

        A total of 189 strains (Streptococcus agalactiae and non-Streptococcus agalactiae 110, Staphylococcus aureus 63, and E. coli 16) isolated from bovine mastitie milk samples by "The Connecticut Mastitis Control Program" in dairy herds were examined for drug susceptibility to 8 drugs and analysed the rate of multiple resistant patterns. 1. All of the isolates were resistant to antimicrobial agents such as penicillin (PC), streptomycin (SM), kanamycin(KM), carbenicillin (CA), lincomycin (LM), gentamicin (GM), and tetracycline (TC), singly or multiply. The isolates were more susceptible to CA (84.1%),PC (78.9%), and SM (78.4%) than the the other drugs such as GM (51.8%), KM (48.7%), TC (19.6%) and LM (19.0%) in order. 2. The multiple resistant isolates (96.3%) were more than those of singly resistant isolates (3.7%) and 58 different drug resistant patterns were observed. Among 7 singly resistant isolates, CP was the commonest. While among 182 multiple resistant isolates, CP-KM-LM-TC-GM, CP-LM-TC, CP-LM-TC-GM, PC-CP-SM-LM-TC-GM, CP-KM-LM-TC, and CP-LM patterns were frequently encounted. 3. The strains of streptococcus spp. were more susceptible to CA (90.1%) and SM (82.9%) than the other drugs such as KM (43.2%), GM (38.7%), LM (13.5%), CP (10.8%) and TC (10.8%). Among them CP-KM-LM-TC-CM pattern was frequently encounted. 4. The strains of Sta. aureus were more susceptible to PC (74.6%),CA (69.8%), SM (65.1%) and GM (63.5%) than the other drugs such as KM (46.0%), CP (22.2%), TC (15.9%) and LM (9.5%). Among them CP-LM-TC pattern was commonly encounted. 5. The strains of E. coli were more susceptible to CA (100%) and KM (75.0%) tnan TC (9.5%). But the other drugs such as PC, SM, GM, CP and LM were not. Among them PC-CP-SM-LM-TC-GM pattern was commonly encounted.

      • 전북지방 젖소의 유방염 검색

        조정곤,김종면,최민순,채효석,강명대,송희종 全北大學校 附設 畜産開發硏究所 1987 畜産開發硏究報告 Vol.1 No.-

        A total of 444 quarters milk samples of 111 dairy cattle in Chonbuk area were examined for infection rete and causative agents of mastitis by "the laboratory procedures used in the Connecticut Mastitis Control Program (CMCP) and California mastitis Test (CMT)". The results obtained were as follows: 1. Of 444 samples, 39.2% had positive CMCP value and 24.4% positive CMT reaction. 2. One hendred and seventy four (39.2%) from 82 cattle (73.9%) were found to infected with mastitis. It was found that 8(1.8%0 of the infected quarters were clinical mastitis and all of the rest were subclinical mastitis. 3. The main causative agents were found to Staphylococcus aureus (63 quarters), Streptococcus agalactiae (56 quarters), non-Str. agalactiae streptococci (54 querters), Escherichia coli (19 quaters), the actual total number of quarters detected as mastitis would be 174, as 18 of these quarters showed multiple infection with two different organisms. 4. Having examined the number of infection quarter per head of mastitis in dairy cattle sampling, major finding were that the average number of infection quarters to total dairy cattle exemined was 1.57 quarters, and that of the infected cattle was 2.1 quarters. Infected quarters in cattle with 1, 2, 3 and 4 were noted 27(32.9%), 28(34.1%), 17(20.7%), and 10(12.3%), respectively.

      • SCOPUSKCI등재

        Effect of fermented Achyranthes japonica (Miq.) Nakai extract on osteoarthritis

        Hyo Seok Kang,Hee Seop Lee,Heui-Jong Yu,Seon Hyeong Jang,Yoonhee Seo,Hong Yon Cho,Soo Young Choe 한국식품과학회 2017 한국식품과학회지 Vol.49 No.1

        The present study was conducted to evaluate the anti-inflammatory and anti-arthritic effects of fermented Achyranthes japonica (Miq.) Nakai extract (FAJE). The FAJE was effective in nitrogen oxide (NO) scavenging in RAW264.7 cells. In the case of experimental Sprague Dawley (SD) rats injected with monosodium iodoacetate (MIA), the levels of TNF-α and IL-1β in blood increased in the osteoarthritis-induced group while decreasing in the group administered with FAJE. In addition, MMP-2 and MMP-9 in cartilage tissues increased in the osteoarthritis-induced group, but decreased in the group treated with FAJE. Cartilage examination indicated that the osteoarthritis-induced group exhibited cartilage erosion and cell degeneration, but in the FAJE administered group the tissue, conditions were recovered and cartilage proteoglycan was increased. Therefore, FAJE clearly showed anti-inflammatory effects and this suggests it is effective for recovery from osteoarthritis induced by MIA.

      • Evaluation of hepatotoxicity of chemicals using hepatic progenitor and hepatocyte-like cells derived from mouse embryonic stem cells: effect of chemicals on ESC-derived hepatocyte differentiation.

        Kang, Seok-Jin,Jeong, Sang-Hee,Kim, Eun-Joo,Cho, Joon-Hyoung,Park, Young-Il,Park, Sung-Won,Shin, Hyo-Sook,Son, Seong-Wan,Kang, Hwan-Goo Princeton Scientific Publishers 2013 Cell biology and toxicology Vol.29 No.1

        <P>Embryonic stem cell testing is an alternative model system to assess drug and chemical toxicities because of its similar developmental characteristics with in vivo embryogenesis and organogenesis. This study evaluated the toxicity of chemicals at specific developmental stages of mouse embryonic stem cell (ESC)-derived hepatic differentiation; hepatic progenitor cells (HPCs), and hepatocyte-like cells (HCs). The toxic effects of carbon tetrachloride (CCl(4)), 5-fluorouracil (5-FU), and arsanilic acid (Ars) were evaluated by measuring the expressions of Cytokeratin (CK18) and GATA binding protein 4 (GATA-4) and the activities of aspartate transaminase (AST), lactate dehydrogenase (LDH), and alkaline phosphatase (ALP) during the hepatic differentiation process. Non-toxic doses of three chemicals at a range of 25 to 500?μM for CCl(4), 12.5 to 800?nM for 5-FU and 6.25 to 400?mM for Ars were treated. In the CCl(4)-treated group, significant decreases (P?<?0.05) of the marker expression were observed by more than 300?μM from day 10 in CK18 and by more than 400?μM of CCl(4) from day 22 in GATA-4, respectively. However, both markers were decreased (P?<?0.01) by treatments of all doses at day 40. In the 5-FU-treated group, the expressions of two proteins were not affected by any of the doses at day 10 and 22, whereas the GATA-4 expression was decreased (P?<?0.05) by more than 400?nM of 5-FU at days 28 and 40. In the Ars-treated group, the CK18 expression was inhibited (P?<?0.05) by more than 100?mM of Ars at day 22 but showed a tendency to recover. Although the GATA-4 was inhibited by all doses at day 22, the inhibition of GATA-4 recovered at days 28 and 40. ALP activities of three chemicals were significantly increased (P?<?0.05) by a dose-dependent manner. The activities of AST and LDH were prone to be increased by more than 300?μM of CCl(4,) but not affected by all doses of 5-FU except for 800?nM of 5-FU in AST activities. In the Ars, the enzyme activities were significantly increased (P?<?0.05) by more than 50?μM of Ars in AST and more than 6.25?μM of Ars in LDH. The present results indicate that CCl(4) has a more toxic effect on HCs, whereas Ars is more toxic to HPCs. Additionally, in vitro alternative testing using ESC-derived HPCs and HCs could provide useful information on chemical toxicity during the hepatic differentiation process and could be a useful model system for assessing chemical hepatotoxicity.</P>

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