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- 저자 : K Sugiura (검색결과 59 건)
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Sugiura, Tsutomu,Yamamoto, Kazuhiko,Horita, Satoshi,Murakami, Kazuhiro,Tsutsumi, Sadami,Kirita, Tadaaki Korean Academy of Periodontology 2016 Journal of Periodontal & Implant Science Vol.46 No.3
Purpose: This study investigated the effects of bone density and crestal cortical bone thickness at the implant-placement site on micromotion (relative displacement between the implant and bone) and the peri-implant bone strain distribution under immediate-loading conditions. Methods: A three-dimensional finite element model of the posterior mandible with an implant was constructed. Various bone parameters were simulated, including low or high cancellous bone density, low or high crestal cortical bone density, and crestal cortical bone thicknesses ranging from 0.5 to 2.5 mm. Delayed- and immediate-loading conditions were simulated. A buccolingual oblique load of 200 N was applied to the top of the abutment. Results: The maximum extent of micromotion was approximately $100{\mu}m$ in the low-density cancellous bone models, whereas it was under $30{\mu}m$ in the high-density cancellous bone models. Crestal cortical bone thickness significantly affected the maximum micromotion in the low-density cancellous bone models. The minimum principal strain in the peri-implant cortical bone was affected by the density of the crestal cortical bone and cancellous bone to the same degree for both delayed and immediate loading. In the low-density cancellous bone models under immediate loading, the minimum principal strain in the peri-implant cortical bone decreased with an increase in crestal cortical bone thickness. Conclusions: Cancellous bone density may be a critical factor for avoiding excessive micromotion in immediately loaded implants. Crestal cortical bone thickness significantly affected the maximum extent of micromotion and peri-implant bone strain in simulations of low-density cancellous bone under immediate loading.
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Sugiura, Tsutomu,Yamamoto, Kazuhiko,Horita, Satoshi,Murakami, Kazuhiro,Tsutsumi, Sadami,Kirita, Tadaaki Korean Academy of Periodontology 2017 Journal of Periodontal & Implant Science Vol.47 No.4
Purpose: The purpose of this study was to investigate the effects of implant tilting and the loading direction on the displacement and micromotion (relative displacement between the implant and bone) of immediately loaded implants by in vitro experiments and finite element analysis (FEA). Methods: Six artificial bone blocks were prepared. Six screw-type implants with a length of 10 mm and diameter of 4.3 mm were placed, with 3 positioned axially and 3 tilted. The tilted implants were $30^{\circ}$ distally inclined to the axial implants. Vertical and mesiodistal oblique ($45^{\circ}$ angle) loads of 200 N were applied to the top of the abutment, and the abutment displacement was recorded. Nonlinear finite element models simulating the in vitro experiment were constructed, and the abutment displacement and micromotion were calculated. The data on the abutment displacement from in vitro experiments and FEA were compared, and the validity of the finite element model was evaluated. Results: The abutment displacement was greater under oblique loading than under axial loading and greater for the tilted implants than for the axial implants. The in vitro and FEA results showed satisfactory consistency. The maximum micromotion was 2.8- to 4.1-fold higher under oblique loading than under vertical loading. The maximum micromotion values in the axial and tilted implants were very close under vertical loading. However, in the tilted implant model, the maximum micromotion was 38.7% less than in the axial implant model under oblique loading. The relationship between abutment displacement and micromotion varied according to the loading direction (vertical or oblique) as well as the implant insertion angle (axial or tilted). Conclusions: Tilted implants may have a lower maximum extent of micromotion than axial implants under mesiodistal oblique loading. The maximum micromotion values were strongly influenced by the loading direction. The maximum micromotion values did not reflect the abutment displacement values.
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일본 '레즈비언 전후사' 다시 읽기: '성욕'이라는 관점의 결여에 관하여
SUGIURA Ikuko 서울대학교 일본연구소 2014 일본비평 Vol.- No.11
How has modern Japan presented the “female intimacy”? This paper sheds light on the existing historical descriptions and how its development does not necessarily reflect the “history of sexuality,” and argues that the history of lesbian movements after the 1970s must be recaptured from the perspective of “sexual desire.” In this paper, the “perspective of sexual desire” questions how the concept of “sexual desire,” which has been constructed in various ways since the Taisho period, had dealt with discourses on “female intimacy” and “a woman who loves a woman.” In Japan, the term “lesbian” spread widely in the late half of the 1960s, and in the 1970s a number of information on lesbianism was available through the media. A number of researches on the history of lesbians have been published, but none of them have analyzed it as a discourse that create both spheres and experiences of lesbians’ (and women’s) sexual desires. In other words, it can be said that, in Japan, “postwar history of sexuality” on lesbians has not yet been written. This paper first deals with the period from the 1910s to the 1960s during which a concept of “sexual desire” was imported before the advent of lesbianism in Japan, and, from the perspective of “sexual desire,” analyzes how modern Japan attached meanings toward “female intimacy” and “a woman who loves a woman.” Second, the paper briefly touches upon the discourse on lesbianism found in the magazines after the 1970s, and examines the contemporary significance of adopting the “perspective of sexual desire.”
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Katsuaki Sugiura,Takuyuki Yoshioka,Koki Inoue 한국산림과학회 2013 Forest Science And Technology Vol.9 No.3
The purpose of this study was to compare the present condition of forest management in Asian countries using results of evaluations from Forest Stewardship Council (FSC) certification bodies. In recent years, the number of FSC-certified forests has increased in Asia. Our investigation examined certified forests in Asian countries, which, as of 2009, accounted for 2.39% of total global certified forest area (2,761,603 ha). Materials were taken from summary evaluations published by each FSC certification body on its respective website. The FSC uses 10 principles and 56 criteria in its evaluation. We investigated the items that the FSC certification bodies consider to be areas that require improvement. Of these principles and criteria, the following were cited by the certification bodies as RI (requiring improvement) in nearly all Asian countries: principle four, “community relations and worker’s rights”; principle six, “environmental impacts”; principle seven, “management plan”; and principle eight, “monitoring and assessment”. In addition, there were differences corresponding to each country with respect to the other principles and criteria. Laos, Indonesia, and Malaysia in particular were found to have a number of problems. Thus, while there were differences in the principles that qualified as RI in each country, there were also common weak points that require improvement throughout the continent. Asian countries should be mindful of these deficiencies and take measures to improve them, in order to achieve sustainable forest management practices.
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Role of anti-aging factor and reactive sulfur species in the pathogenesis of COPD
( Hisatoshi Sugiura ) 대한결핵 및 호흡기학회 2019 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.127 No.-
Cellular senescence is observed in the lungs of patients with COPD and may contribute to the disease pathogenesis. Growth differentiation factor 11 (GDF11) belongs to the transforming growth factor β superfamily and was recently reported to be a circulating protein that may have rejuvenating effects in mice. We aimed to investigate the amounts of GDF11 in the plasma and the lungs of patients with COPD and elucidate the possible roles of GDF11 in cellular senescence. The plasma levels of GDF11 were investigated in two separate cohorts by western blotting. The localisation and expression of GDF11 in the lungs were investigated by immunohistochemistry and quantitative reverse transcription PCR, respectively. The effects of GDF11 on both cigarette smoke extract (CSE)-induced cellular senescence in vitro and on elastase-induced cellular senescence in vivo were investigated. The levels of plasma GDF11 in the COPD group were decreased compared with the control groups in the two independent cohorts. The levels of plasma GDF11 were significantly positively correlated with pulmonary function data. The mRNA expression of GDF11 in mesenchymal cells from the COPD group was decreased. Chronic exposure to CSE decreased the production of GDF11. Treatment with GDF11 significantly inhibited CSE-induced cellular senescence and upregulation of inflammatory mediators, partly through Smad2/3 signaling in vitro. Daily GDF11 treatment attenuated cellular senescence and airspace enlargement in an elastase-induced mouse model of emphysema. The decrease in GDF11 may be involved in the cellular senescence observed in COPD. Furthermore, oxidative stress is a major aetiological factor driving COPD. Recently recognised as potent antioxidants, reactive persulfide and polysulfide species are biosynthesised by cystathionine β-synthase and cystathionine γ-lyase. The production of reactive persulfide and polysulfide species in the lungs of patients with COPD remain unknown. So, we aimed to examine the production of reactive persulfides and polysulfides, such as glutathione persulfide (GSSH), cysteine persulfide (CysSSH) and glutathione trisulfide (GSSSH), in lung-resident cells and epithelial lining fluid (ELF) obtained from patients with mild to moderate COPD. Lung tissues, primary lung cells, ELF and sputum were obtained. The amounts of reactive persulfides and polysulfides in the cells and ELF were measured by liquid chromatography-tandem mass spectrometry with β-(4-hydroxyphenyl) ethyl iodoacetamide as a trapping agent for hydroper/polysulfides. The amounts of synthases in the lung tissues, sputum and primary cells were quantified. The amounts of GSSH, CysSSH and GSSSH were decreased in the lung cells and ELF from patients with COPD. The amounts of reactive persulfides and polysulfides in the lung cells had a positive correlation with the degree of airflow limitation. By contrast, the amounts of the synthases were increased in the lung tissues and sputum cells of patients with COPD. We have identified a decrease in reactive persulfide and polysulfide species in the lungs of patients with COPD. These data suggest that the newly detected antioxidants reactive persulfides and polysulfides could be associated with the redox balance in the lungs of patients with COPD.
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( Nobuhiko Sugiura ) 한국금융법학회 2011 金融法硏究 Vol.8 No.1
This article describes a comprehensive overview about the contents of Japanese Financial Instruments and Exchange Act ("FIEA") and its future task. FIEA was enacted and promulgated in June 14, 2006 as the amendment of the Securities and Exchange Act. The amendment largely consists of the following four pillars: (ⅰ) Establishing a cross-sectional legislative framework for investor protection covering financial products with strong investment characteristics (the so-called legal framework for investor services) (ⅱ) Enhancing disclosure requirements (ⅲ) Ensuring appropriate management of self-regulatory operations by exchanges (ⅳ) Strict countermeasures against unfair trading Later, on July 31, 2007, the "Cabinet Order on the Development, etc. of Relevant Cabinet Orders for Enforcement of the Act for the Amendment of the Securities and Exchange Act, etc. and the Act for the Development, etc. of Relevant Acts for Enforcement of the Act for the Amendment of the Securities and Exchange Act, etc." were approved by the Cabinet. On the same day, cabinet orders, cabinet office ordinances, etc. concerning the Financial Instruments and Exchange Act (FIEA) were published, and the FIEA, which incorporates these amendments, took effect on September 30, 2007. The contents of the Act have been amended almost year by year, reflecting the significant changes of financial market conditions for last a few years. This article provides the details of FIEA`s restrictions to financial institutions, investor protection system and its further issues to be solved in future.
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