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      • KCI등재

        대학생의 성찰 구조 인식과 성찰 글쓰기 교수법 연구

        박지윤 ( Park¸ Jiyoon ) 한국현대언어학회 2021 언어연구 Vol.37 No.2

        The Journal of Studies in Language 37.2, 161-179. The purpose of this study is to analyze the types of reflection structures that the university students perceive in reflection writing and to expand their reflection structure experiences to “self” → to “others” → to “social and world” through flipped learning teaching methods. With the rapid transition to the online educational environment in the post pandemic era, students must consider extending their reflection structure awareness in the online environment. The reflection structure is efficient to expand the reflection structure extensions in a way of sharing among students. To this end, flipped learning and application evernote was utilized. It is meaningful that the research mainly focused on research such as reflection writing teaching methods, necessity, and utility, analyzed the reflection structure recognized by the university students and expanded awareness through reflection structure sharing in an online education environment. (Woosuk University)

      • KCI등재후보

        Ductal Carcinoma in situ with Multicystic Changes in a Patient with Interstitial Mammoplasty via Paraffin Injection: MRI and Pathological Findings

        Park, Jiyoon,Woo, Ok Hee,Kim, Chungyeul,Cho, Kyu Ran,Seo, Bo Kyoung Korean Society of Magnetic Resonance in Medicine 2015 Investigative Magnetic Resonance Imaging Vol.19 No.2

        Direct injection of foreign material, such as liquid paraffin and silicone, into the breast can induce a foreign body granulomatous reaction and fibrosis, resulting in hard, nodular breast masses and architectural distortion that can mimic neoplasm. Conventional methods, including physical examination, mammography, and ultrasonography are of little use to differentiate between foreign body-induced mastopathy and breast cancer. In patients with foreign body injection such as breast augmentation, dynamic contrast enhanced MR imaging is an excellent imaging modality. Here, the authors report the MR imaging and pathological findings of ductal carcinoma in situ (DCIS) with multicystic changes in a 41-year-old woman with a previous history of interstitial mammoplasty by paraffin injection.

      • Nonspecific protein labeling of photoaffinity linkers correlates with their molecular shapes in living cells

        Park, Hankum,Koo, Ja Young,Srikanth, Yellamelli V. V.,Oh, Sangmi,Lee, Jiyoon,Park, Jongmin,Park, Seung Bum The Royal Society of Chemistry 2016 Chemical communications Vol.52 No.34

        <P>Herein we report molecular shape-dependent nonspecific labeling of photoaffinity linkers (PLs) in the cellular proteome. Linear PLs have a greater tendency to engage in nonspecific binding than branched PLs. Exploiting this property, we discovered a smaller branched diazirine-based PL as the best photoaffinity probe with minimal nonspecific binding characteristics from among 5 probes with different PLs.</P>

      • Comparison of mammography, digital breast tomosynthesis, automated breast ultrasound, magnetic resonance imaging in evaluation of residual tumor after neoadjuvant chemotherapy

        Park, Jiyoon,Chae, Eun Young,Cha, Joo Hee,Shin, Hee Jung,Choi, Woo Jung,Choi, Young-Wook,Kim, Hak Hee Elsevier 2018 European journal of radiology Vol.108 No.-

        <P><B>Abstract</B></P> <P><B>Background</B></P> <P>To compare the accuracy of mammography (MG), digital breast tomosynthesis (DBT), automated breast ultrasound (ABUS) and magnetic resonance imaging (MRI) for the assessment of residual tumor extent in breast cancer after neoadjuvant chemotherapy (NAC).</P> <P><B>Methods</B></P> <P>Fifty-one stage II-III breast cancer undergoing NAC were enrolled from March 2015 to December 2016. The longest diameter of residual tumor measured with MG, DBT, ABUS and MRI was compared with the pathologic tumor size. Statistical analysis was performed using intraclass correlation coefficients (ICC) and marginal homogeneity test. Receiver operating characteristics (ROC) analysis was used to evaluate the diagnostic performance for predicting pathologic complete response (pCR).</P> <P><B>Results</B></P> <P>MRI size correlated well with pathology (ICC = 0.83), significantly better than MG, DBT and ABUS size (ICC = 0.56, ICC = 0.63 and ICC = 0.55, respectively). The discrepancy between MRI and pathology was statistical different from that of MG and ABUS (p = 0.0231 and 0.0039, respectively), but not different from that of DBT (p = 0.5727). For predicting pCR, MRI and DBT had a better performance compared to MG and US (area under the ROC curve: 0.92, 0.84, 0.72, 0.75, respectively; p = 0.3749 for DBT, p = 0.0972 for MG and p = 0.0596 for ABUS, when MRI being reference).</P> <P><B>Conclusions</B></P> <P>MRI and DBT allow more accurate assessment of tumor size compared to pathology compared with MG and ABUS. MRI and DBT outperform MG and ABUS in the prediction of pathologic complete response.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The information from MRI and DBT was better correlated with pathology than that from MG and ABUS for predicting residual tumor size after NAC. </LI> <LI> For predicting pCR, MRI and DBT outperform MG and ABUS. </LI> <LI> Among molecular subtypes, luminal B tumors showed very good correlation with DBT. </LI> </UL> </P>

      • KCI등재후보

        Epigenetic and Metabolic Changes in Diffuse Intrinsic Pontine Glioma

        ( Jiyoon Park ),( Chan Chung ) 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 2023 Brain Tumor Research and Treatment Vol.11 No.2

        Diffuse midline glioma (DMG), hitherto known as diffuse intrinsic pontine glioma (DIPG), is a rare and aggressive form of brain cancer that primarily affects children. Although the exact cause of DMG/DIPG is not known, a large proportion of DMG/DIPG tumors harbor mutations in the gene encoding the histone H3 protein, specifically the H3K27M mutation. This mutation decreases the level of H3K27me3, a histone modification that plays a vital role in regulating gene expression through epigenetic regulation. The mutation also alters the function of polycomb repressive complex 2 (PRC2), thereby preventing the repression of genes associated with cancer development. The decrease in H3K27me3 caused by the histone H3 mutation is accompanied by an increase in the level of H3K27ac, a post-translational modification related to active transcription. Dysregulation of histone modification markedly affects gene expression, contributing to cancer development and progression by promoting uncontrolled cell proliferation, tumor growth, and metabolism. DMG/DIPG alters the metabolism of methionine and the tricarboxylic acid cycle, as well as glucose and glutamine uptake. The role of epigenetic and metabolic changes in the development of DMG/DIPG has been studied extensively, and understanding these changes is critical to developing therapies targeting these pathways. Studies are currently underway to identify new therapeutic targets for DMG/DIPG, which may lead to the development of effective treatments for this devastating disease.

      • KCI등재

        중국계 다문화가정 아동의 한국어 설측음의 권설음화 조음 현상 연구

        박지윤(JIYOON PARK) 한국문화융합학회 2020 문화와 융합 Vol.42 No.8

        본 연구의 목적은 취학 전후인 7세, 9세 중국계(한국계 중국인 제외) 다문화가정 아동의 설측음 조음 오류 현상을 음향음성학적으로 분석하고 그 원인을 고찰하는 데 있다. 아동은 가정에서부터 언어 습득이 일차적으로 이루어지는데 한국어 숙달도가 낮은 중국인 어머니로부터 양질의 한국어 교육을 받지 못한 다문화가정 아동은 또래의 한국인 아동보다 한국어 조음 오류가 높다. 특히, 중국계 다문화가정 아동은 설측음을 중국어 권설음화로 조음하는 경우가 많은데, 아동의 연령이 어릴수록, 중국인 어머니의 한국어 숙달도가 낮을수록 그 오류는 더 많았다. 다문화가정 아동의 한국어 설측음의 권설음화로 조음하는 현상은 중국인 어머니의 모어인 중국어의 권설음 영향 때문인 것으로 보았다. 얼화운의 음향적 특징은, F3의 주파수가 큰 폭으로 하강하여 F2에 접근하는데, F2에 접근할수록 권설이다. 그 이유는 F2가 혀의 앞뒤 위치인데, 혀가 뒤로 갈수록 F2는 낮아지기 때문이다. 그렇기 때문에 F3의 주파수가 큰 폭으로 하강하여 F2에 접근한다는 것은 권설음에 가깝다는 뜻이다. 다문화가정 아동은 F3이 F2로 하강하는 현상을 볼 수 있다. 이는 일반 가정 아동에게서 나타나는 현상은 아니고, 다문화가정 아동에게서 나타나는 현상인데, 다문화가정 중국인 어머니도 실험 결과 다문화가정 아동과 동일한 현상을 보였다. 이를 통해 중국계 다문화가정 아동의 한국어 설측음은 중국인 어머니의 모어인 중국어 권설음 영향을 받는 것을 알 수 있다. 본 연구는 그동안 미진하였던 중국계 다문화가정 아동의 설측음 조음 오류를 실험 연구를 통해 오류 양상을 분석하고, 그 원인을 중국인 어머니의 모어인 중국어 권설음과 한국어 설측음의 음운 체계 대조로 보고 이를 음향음성학적으로 밝혔다는 점에서 의의를 가진다. This study carries out an acoustic and phonetic analysis of the pronunciation of 7-9-year-old pre-school Chinese children in Korea (excluding mixed Korean-Chinese children) from multicultural families, both before and after school. It then considers the cause of their pronunciation errors. Children are primarily taught language at home. In Korea, children who do not receive high-quality Korean-language education from Chinese mothers with low proficiency in Korean make more minor errors when speaking Korean than Korean children of the same age. In particular, children from multicultural Chinese families often pronounce Korean words using a lateral-Chinese retroflex sound; the younger the child and the lower the Chinese mother s proficiency in Korean, the more errors that child is likely to make. This phenomenon among children from multicultural families has been attributed to the prevalence of the retroflex sound in Chinese, their mothers’ native tongue. The acoustical feature of this rhotacization is a sharp fall in the F3 frequency, as it approaches F2. F2 resonates at the front and back of the tongue; as the tongue moves lower, so does F2. Approaching F2 with a large drop in the frequency of F3 creates a sound that is close to the Chinese retroflex sound. Children from multicultural families are aware of F3 falling to F2. Although this phenomenon occurs in children and Chinese mothers in multicultural families, it is never seen in children from Korean families. This shows that children from multicultural families are influenced by their mother s native language. This study makes a meaningful contribution to the literature by analyzing the error patterns found in the speech of Chinese multicultural children through experimental research. Using an acoustic phonetics analysis, It demonstrates that these error patterns are caused by the Chinese mother’s native language and the contrast between the Chinese and Korean phonological systems.

      • KCI등재

        The Effect of Outside CEO Successor and R&D Intensity on Internationalization

        Kim Jiyoon,Kim Changsu,Park Jong-Hun,Park Hyunjin 한국국제경영관리학회 2020 국제경영리뷰 Vol.24 No.1

        본 연구의 목적은 최고경영자 교체유형과 연구개발집약도, 그리고 기업의 국제화 간의 관계를 분석하는 데 있다. 최고경영층 이론에 따르면 외부영입 CEO는 내부승계 CEO에 비해 전략적 동기화하는 측면에서 기업의 국제화에 더욱 더 적극적이다. 자원기반이론에 따르면 전략적 경영자원의 가용성이라는 측면에서 기업의 연구개발집약도가 높을수록 기업의 국제화 수준은 높아지는 경향이 있다. 본 연구에서는 2008년부터 2015년 기간의 KOSPI200 기업 중 89개 기업을 대상으로 이들 기업에서 발생한 121회의 CEO 교체를 분석하였다. 분석 결과, 외부영입 CEO가 내부승계 CEO보다 기업의 국제화에 더욱 더 적극적인 것으로 나타났다. 또한 외부영입 CEO의 전략변화에 대한 동기와 기업의 연구개발역량이 동시에 충족되는 경우에 기업의 국제화는 가장 활발하게 추진되는 것으로 나타났다. Based on the upper echelons theory and the resource-based view (RBV), our study examines the interaction effect of the outside CEO successor and the level of R&D intensity on a firm"s degree of internationalization. We hypothesized that both motivation (outside the CEO successor"s willingness to make a strategic move) and capability (the technological capability enabling the strategic move) are key factors in successfully pursuing a firm"s internationalization. Using samples from Korean manufacturing firms for the period from 2008 through 2015, we analyzed CEO turnover data (N = 121) of 89 firms. Our results confirm that outside CEO succession is positively related to the internationalization of firm sales. However, the firm’s degree of R&D intensity itself was not significantly associated with its internationalization. The highest degree of internationalization was achieved when both conditions – outside CEO successor as well as R&D intensity of a firm - were met. Our results indicate that the internationalization strategy would be a joint function of the strategic motivation of an outside CEO successor and the technological capability of a firm. While this finding is admittedly very tentative, it holds substantive promise for further investigation into the interactive effect of strategic motivations and firm capabilities on firm internationalization. This study also offers practical implications for firms that pursue internationalization.

      • KCI등재
      • KCI등재

        외래어 어두경음화 발음의 원인과 사회계층

        박지윤(JiYoon Park) 한국콘텐츠학회 2021 한국콘텐츠학회논문지 Vol.21 No.2

        사회계층에 따라 어두경음화가 나타나는 양상에 주목할 필요가 있다. 학력이 높을수록, 공식적이고 격식적인 자리일수록 영어 원어와 가깝게 발음하기 위해 어두경음화를 되도록 피하는 경향이 나타난다. 이에 대해 실험 조사와 Praat 음성 분석 프로그램을 통해 사회계층에 따라 외래어 어두경음화 약화 현상을 증명하여 밝히는 것이 본 연구의 목적이다. 외래어 어두경음화 원인에 대해 기존 논의에서는 표현 강화, 현대 사회 경쟁의 결과, 무조건적인 경음화, 국어사적 분석, 한국어와 영어의 음성음운 차이 기인, 외래어 발음의 규칙화 시도 등으로 다양하게 논의되어 왔으나, 사회계층에 기인한 분석은 부족한 실정이다. 본고에서는 실험 조사와 음성 분석 프로그램인 Praat을 이용하여 학력이 높을수록, 공식적이고 격식적인 자리일수록 외래어 어두경음화 현상이 약하게 나타난다는 것을 밝혔다. 외래어 어두경음화 발음 여부는 자신의 신분과 계층을 표출할 수단으로 보는 심리적 기제로 작용함을 알 수 있다. It is necessary to pay attention to the appearance of word-initial glottalization among social classes. The higher the academic ability, the more formal it is, the more likely it is to avoid word-initial glottalization due to the psychological factors that are close to the English pronunciation. The purpose of this study is to prove and clarify this through experimental research and the Praat voice analysis program. In previous discussions on word-initial glottalization, there have been various discussions such as strengthening expressions, the conclusion of competition of modern society, Korean historical analysis, differences in Korean and English phonetics, and attempts to regularize the pronunciation of loanwords. In this paper, it was revealed that the higher the academic ability, the weaker the pronunciation of loanwords word-initial glottalization appears in formal and formal situations, by using experimental research and voice analysis program Praat. The presence or absence of pronunciation of the initial specification of loanwords acts as a psychological base for expressing ones status and hierarchy.

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