폐광미 조립분을 잔골재로 활용한 시멘트 경화체의 특성

윤성진,문경주,소양섭 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1(구조계)

Presently Metal-Mine waste is filled in the revertment, soil dike and undercurrent facilities of waste matter at piles, but this ways are not fundamental method of waste matter and it takes long time to maintain and it spends a lot of money so that we have need of a effective treatment plan and recycling method. In this study, to predict a effective treatment plan of Metal-mine waste(tailing) that is heaped. We observe tailing's physical and chemical basic features. According to examinate a hydration using tailing we evaluate its utilizable possibility as construction materials.

폐인산석고의 증기양생용 콘크리트 혼화재로서의 적용성 평가

안양진,윤성진,문경주,소양섭 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2(구조계)

The purpose of this study evaluates possibilities of waste phsphogypsum into concrete by steam curing admixture. The waste phsphogypsum is made use of 4 types by specific gravity distritubt which is simple and physical dry process and 4 forms(CaSO₄ㆍ2H2O, Type β-CaS0₄ㆍ1/2H2O, TypeⅢ-CaS0₄and TypeⅡ-CaS0₂) which is changed to in low temperature. As a result, by specific gravity distritubt all the types of compressive strength is higher than OPC. In Type β-CaS0₄ㆍ1/2H2O and TypeⅢ-CaS0₄cases, these is similar to TypeⅡ-CaS0₂from strength and are great in the effect of strength improvement.

폐인산석고를 혼입한 시멘트 모르타르의 내산성

안양진,윤성진,문경주,송훈,소양섭 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)

The purpose of this study is to evaluate the acid resistance of cement mortar admixed with waste phosphogypsum by steam curing admixture. Waste Phosphogypsum is a by-product from the phosphoric acid process for manufacturing fertilizers. It consists mainly of CaSO₄·2H₂O and contains some impurities such as P₂O_5, F^(-) and organic substances. The waste phosphogypsums is made use of 4 forms(Dihydrate, β-Hemihydrate, Ⅲ-Anhydrite and Ⅱ-Anhydrite) which were changed to in low temperature of calcination. The mass change and reduction ratio of compressive strength of cement mortar are investigated to evaluate the acid resistance. The specimens of cement mortar were immersed in HCI(5%) and H₂SO₄(5%, 10%) during 14, 28 and 56days. As a result, mass change and reduction ratio of compressive strength of cement mortar admixed with waste phosphogypsum are lower than cement mortar contained OPC alone. Also, Ⅲ-Anhydrite is comparable to Ⅱ-Anhydrite in acid resistance. Therefore, Ⅲ-Anhydrite phosphogypsum calcined at lower temperature could be used as steam curing admixture for concrete 2th production.

폴리에스테르 모르타르용 충전재로서 금속광산 폐광미의 활용 연구

윤성진,최낙운,문경주,소양섭 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2

The purpose of this study is to examine the basic properties of polyester mortars using fine tailing(FT) as a filler. The FT is obtained by centrifugal separation of tailing(TA), and checked for basic properties of shape, particle size distribution, chemical composition, resin absorption. Polyester mortars with FT and ground calcium carbonate(GC) are tested for working life, flexural and compressive strengths. The test results showed that FT has much the same properties as GC in the shape, size and resin absorption. The working life of the polyester mortars is lengthen with an increase in the filter/binder ratio. The polyester mortars with a filter/binder ratio of 1.0 have the maximum flexural and compressive strengths.

정신분열병과 Neurotensin 수용체 유전자 다형성의 연합 연구

이유상,김형배,한진희,채영규,이정식,이혜순,주연호,김형섭,최인근,양병환 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.6

연구목적: Neurotensin(NT)은 NT수용체와 결합하여 그 효과를 나타내는 neuromodulator 혹은 neurotransmitter로서 대뇌에서 도파민의 분비를 조절하는데 중요한 역할을 한다. 근래의 연구에 의하면 NT와 그 수용체는 대뇌에서 항정신병 약물의 효과를 매개하는 것으로 생각되고 있으며 약물치료를 받지 않은 정신분열병 환자의 뇌척수액에서 NT의 양이 적으로 보고되고 있어 이들은 정신분열병과 깊은 관련을 가지고 있을 것으로 추정된다. 최근 NT수용체의 유전자의 3`인접영역에서 정보가치가 높은 4 염기반복 다형성이 발견되어 이를 유전 표지자로 하여 정신분열병과의 연합을 알아보았다. 방 법: 서로 혈연관계에 있지 않은 정신분열병 환자 120명(남자 91명, 여자 29명)과 정상 대조군 106명(남자 84명, 여자 22명)을 대상으로 하였다. PANSS를 사용하여 양성 및 음성을 알아보았다. 말초혈액에서 DNA를 분리한 후에 중합효소연쇄반응을 사용하여 3`인접영역에 있는 4 염기 반복 다형성을 증폭하였고 silver staining한 후에 유전자형을 관찰하였다. chi-square 검증과 Bonferroni`s correction을 사용하여 환자군과 정상 대조군간의 대립유전자 빈도의 차이를 알아보았다. 또한 양성 및 음성 환자군으로 나누어 차이를 알아보았다. 결 과: 총 23개의 대립유전자가 관찰되었으며, 399bp의 대립유전자(A10)의 빈도가 환자군보다 정상대조군에서 통계적으로 유의하게 높았다(χ²=16.49, df=1, p<0.001). 음성 정신분열병 환자군과 정상대조군 사이의 비교에서는 정상대조군의 A10의 빈도가 환자군보다 유의하게 높았다(χ²=21.33, df=1, p<0.001). 성별 비교에서 남자 정신분열병 환자군은 대조군에 비하여 A10의 분포가 유의하게 적었다. (χ²=13.71, df=1, p<0.001) 결 론: NT 수용체 유전자와 정신분열병사이에 음성연합이 관찰되었다. NT 수용체 유전자가 일부 정신분열병의 발병과정에서 확실하지는 않지만 어떤 종류의 보호기능을 할 수도 있다는 것을 암시한다. Objectives: Neurotensin(NT), of which functions are evoked by its interaction with neurotensin receptors(NTR), coexists with mesolimbic dopamine and regulates endogenous dopamine release. Recent studies have shown that NT with NTR exerts neuroleptic-like activity within the central nervous system and may play an important role in the pathogenesis and in the treatment of schizophrenia. We have examined the gentic association between schizophrenia and tetranucleotide repeat polymorphism in the 3-flanking region of the NTR gene to investigate the possible contribution of the NTR gene to the schizophrenia susceptibility. Methods: Among 23 alleles identified, the subjects were 120 patients(male 91, female 29)with schizophrenia and 106 normal healthy controls(male 84, female 22). They were unrelated native Korean. PANSS was used to determine positive or negative subgroup in the schizophrenic patients. Using polymerase chain reaction and polyacrylamide gel electrophoresis, tetranucleotide repeat polymorphism(CCTT and CTT) in the 3`-flanking region of NTR gene was observed. For a comparison of NTR gene`s allelic frequencies between patients with schizophrenia and normal healthy controls, chi-square test and Bonferroni`s correction was performed. Results: The frequency of A10 allele(base pair size=399)was significantly higher in normal healthy controls than schizophrenia(χ²=16.4902, df=1, p<.000). In the comparison between schizophrenic patients with negative symptoms and normal controls, the frequency of A10 allele was significantly higher in normal healthy control subjects than patients with schizophrenia(χ²=21.33, df=1, p<0.001). In the case of male, the frequency of A10 allele of schizophrenia was significantly higher than normal controls(χ²=13.71, df=1, p<0.001). Conclusions: NTR gene was negatively associated with schizophrenia. NTR gene`s tetranucleotide repeat polymorphism may provide some protective function against schizophrenia.

안면 비대칭을 동반한 골격성 III급 부정교합 환자의 선수술 치험례

Jin-Seob Yang(Jin-Seob Yang),Jung-Hoon Kim(Jung-Hoo Kim),Ji-Yeon Lee(Ji-Yeon Lee) 연세대학교 치과대학 두개안면기형연구소 2023 연세임상교정 Vol.30 No.1

본 증례는 아래턱이 많이 나와서 저작이 힘들어 악교정 수술을 받고 싶다라는 주소로 내원한 19세 여환에 관한 증례보고이다. 심한 골격적 부조화를 나타내는 골격성 III급 부정교합 환자들에게는 악골이나 치조골 분절을 재위치시키는 악교정 수술을 동반한 교정 치료가 필수적이다. 하지만 통상적인 악교정 수술 방식의 경우 술전 교정 과정에서 일시적인 안모의 악화가 일어나며, 이는 환자의 삶의 질과 치료의 만족도에까지 영향을 미친다고 보고되었다. 이에 따라 교정치료에 앞서 악교정 수술을 먼저 시행하는 선수술의 개념이 도입되었다. 그러나 선수술은 통상적인 악교정 수술 방식에 비해 수술 예측도가 떨어지고 수술 교합이 불안정하기에 수술 중에서의 오류가 발생할 수 있고 술후 교합이 설정한 교합과 다르게 형성되는 문제가 생겨 더 심한 재발을 보일 수도 있다. 본 증례는 안면 비대칭을 동반한 골격성 III급 부정교합 환자에서 선수술을 시행하였으나 수술 중 오류로 술후 교합이 예상과 다르게 형성된 환자에서 적절한 술후 교정치료를 통해 안정적인 교합을 형성하였고 심미와 기능의 개선을 얻었기에 이를 보고하고자 한다. In this case report, a 19-year-old patient visited the orthodontic department with a protruded chin and difficulty in mastication as the chief complaints. Orthognathic surgery with orthodontic treatment is essential for patients with skeletal Class III malocclusion and severe skeletal deformities. However, in the conventional orthognathic approach, the facial profile worsens during pre-surgical orthodontic treatment, affecting the patient’s quality of life and satisfaction with the orthodontic treatment. Therefore, the surgery-first approach, which involves performing orthognathic surgery before orthodontic treatment, was introduced. However, the surgery-first approach is less predictable, and post-operative occlusion is more unstable than the conventional orthognathic approach. Therefore, there can be more errors in the surgical procedure, and unstable post-operative occlusion can cause severe relapse. In this case, the patient was treated by the surgery-first approach, but post-operative occlusion was formed differently than simulated due to surgical errors. By performing appropriate post-operative orthodontic treatment, stable occlusion, function, and esthetics could be successfully obtained.

Antidepressant Effect of <i> Tetragonia tetragonoides (Pall.) Kuntze</i> Extract on Serotonin Turnover

Yang, Hyun,Kim, Hye Jin,Hong, Eui-Ju,Pyun, Bo-Jeong,Ko, Byung-Seob,Lee, Hye Won Hindawi 2019 Evidence-based Complementary and Alternative Medic Vol.2019 No.-

<P><I>Tetragonia tetragonoides (Pall.) Kuntze</I> (TTK) is a groundcover found along coastal areas of the Korean peninsula. TTK is traditionally used to improve women's health and treat gastrointestinal diseases. Use of herbal medicines in the treatment of mood disorders has recently been suggested as an alternative therapeutic strategy. In the present study, we determined that consumption of TTK extract ameliorated progression of depressive-like symptoms in ovariectomized (OVX) rats and further examined the mechanisms involved, i.e., synthesis, release, and reuptake(s) of serotonin (also known as 5-HT). We assessed the mRNA expression levels of tryptophan hydroxylases (TPH-1 and TPH-2) and serotonin transporter (SERT) as well as the reuptake activity of serotonin in RBL-2H3 cells. We also determined whether or not TTK extract regulates the serum level of serotonin and improves depressive-like symptoms in 0.5, 1, and 2% TTK-fed OVX female rats in a forced swimming test. Our results show that the mRNA levels of TPH-1 and SERT were significantly reduced, whereas the mRNA level of TPH-2 was dose-dependently elevated by TTK (50 and 100 <I>μ</I>g/mL) in RBL-2H3 cells. TTK significantly inhibited LPS- (lipopolysaccharide-) induced serotonin uptake in RBL-2H3 cells in a dose-dependent manner. The serum level(s) of serotonin was elevated by 1% and 2% TTK treatment in OVX female rats. Moreover, immobility time in the forced swimming test was reduced by 1% and 2% TTK treatment but not altered by 0.5% TTK treatment in OVX female rats. Taken together, these results indicate that TTK may significantly inhibit depressive-like symptoms due to upregulation of serotonin level(s) and regulation of serotonin reuptake activity. Thus, TTK may exert beneficial effects on depression during pre- or/and postmenopausal periods<I> via</I> modulation of serotonin synthesis and metabolism.</P>

Flowering and Fertilization Characteristics and Speedy Breeding in a Protandry Plant Peucedanum japonicum Thunberg

Jin Tae Kim(김진태),Ho Jun Joh(조호준),Hong Seob Yu(유홍섭),Young Sang Park(박영상),Ji Seok Kim(김지석),Yong Hyeok Jeong(정용혁),Ju Young Ahn(안주영),Jae Joon Lee(이재준),Dae Won Kang(강대원),Tae Jin Yang(양태진) 한국약용작물학회 2022 한국약용작물학회 학술대회논문집 Vol.2022 No.1

Session J : Plant Gene Structure and Expression : IMMUNOLOGICAL DETECTION OF GARLIC MOSAIC VIRUS

Jin Nam Choi,Jong Tae Song,Kyoung Ha Han,Jong Seob Lee,Yang Do Choi 생화학분자생물학회(구 한국생화학분자생물학회) 1993 추계학술대회집 Vol.- No.-

Molecular Biological Studies on Korean Garlic Viruses

Jin Nam Choi,Jong Seob Lee,Yang Do Choi 한국응용생명화학회(구 한국농화학회) 1993 한국응용생명화학회 학술발표회 Vol.1993 No.-

To understand the molecular structure and pathogenesis mechanism of Korean garlic virus, we isolated several cDNA clones for garlic virus. The nucleotide sequence comparison among the plant viruses reveals that clone 28-9, a GLV cDNA clone, has similarity to the part encoding the replicase of potexviruses, potato virus X (PVX) and narcissus mosaic virus (NMV). The sequence, G--G-GKS, which has been known to be conserved as G----GKS in various ATP- and GTP-binding proteins is fund. To isolate 3`-end cDNA clones for garlic virus, cDNA library was constructed using garlic virus RNA with oligo (dT) primer. The partial nucleotide sequences of 24 cDNA clones were determined and compared with other plant viruses. As a result, several distinct cDNA clones were obtained. Clone V9 has 81.8 % similarity in nucleotide sequence and 93% in deduced amino acid sequence to the coat protein for garlic mosaic virus sequenced in Japan. The coat protein gene constructed into pRSET-A expression vector was expressed in E. coli BL21 and purified by Ni^(2+)·NTA affinity chromatography. Another clone S64 has 82.6% similarity to garlic virus C genes sequenced in Japan. Clone GV2 has repeating sequences, GAATTGAA and GAATTGAATTGAAAACGATTTCGAAAT. Clones J5 and T13 have direct repeat and clone S106 has inverted repeat. To obtain 5`-end cDNA clone for GLV, 5`-extension was carried out using garlic virus RNA with 5`-primer of clone 28-9. GLV cDNA clones were isolated and their nucleotide sequencing is in progress. To understand the pathogenesis mechanism of garlic virus, the method of nucleic acid diagnosis is developing by slot blot analysis.