Right Atrial Anatomical Remodeling Affects Early Outcomes of Nonvalvular Atrial Fibrillation After Radiofrequency Ablation

Moon, Jeonggeun,Jin Hong, Yoo,Shim, Jaemin,Hwang, Hye-Jin,Kim, Jong-Youn,Pak, Hui-Nam,Lee, Moon-Hyoung,Joung, Boyoung Japanese Circulation Society. 2012 CIRCULATION JOURNAL Vol.76 No.4

<P><B><I>Background:</I></B> The impact of the right atrial (RA) anatomical remodeling on outcomes of atrial fibrillation (AF) after radiofrequency ablation (RFA) is unclear. <B><I>Methods and Results:</I></B> Sixty-three patients (50 men, 57±10 years, 23 persistent AF [PeAF]) who underwent RFA for AF were enrolled. Both RA and left atrial (LA) volumes, measured with multidetector computed tomography, as well as echocardiographic parameters were compared between subjects with early (<3 months, n=13) or 1-year (n=19) recurrence after RFA and without recurrence. The RA volume index (RAVI) was larger (98±21 vs. 77±22ml/m<SUP>2</SUP>) and PeAF was more common (62% vs. 30%) in the early recurrence group (P<0.05 for all), whereas the LA volume index (LAVI) was similar between the 2 groups (78±15 vs. 72±19ml/m<SUP>2</SUP>, P=0.23). Notably, RAVI was the only independent predictor of early recurrence (for each 10ml/m<SUP>2</SUP> increase, OR: 1.650, 95%CI: 1.017-2.677, P=0.04). PeAF was the only independent predictor of 1-year recurrence after RFA (OR: 4.496, 95%CI: 1.110-18.211, P=0.04), whereas RAVI and LAVI were not. <B><I>Conclusions:</I></B> RA anatomical remodeling might affect the early recurrence of AF after RFA. However, the chronicity of AF, rather than RA and LA anatomical remodeling, is a determinant of 1-year recurrence of AF after RFA. (<I>Circ J</I> 2012; <B>76:</B> 860-867)</P>

Apnea-hypopnea Index is Correlated with Pulse Rate in Patients with Sleep-related Breathing Disorder without Hypertension, Cardiovascular Disease, or Diabetes Mellitus

Jeonggeun Moon,Jae Hyoung Park,Seo-Eun Cho,Kwang-Pil Ko,Seung-Heon Shin,Ji-Eun Kim,Jae-Kean Ryu,Seung-Gul Kang 대한정신약물학회 2022 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.20 No.3

Objective: This study aimed to compare the mean pulse rate (PR) and mean blood pressure (BP) between patients with obstructive sleep apnea (OSA) and those with simple snoring (SS) during a 24-hour period, and to investigate the correlation between apnea-hypopnea index (AHI), PR, and BP in sleep-related breathing disorder (SRBD) patients with and without hypertension, diabetes mellitus (DM), and cardiovascular diseases (CVDs). Methods: Ninety SRBD patients underwent full-night polysomnography, and ambulatory BP and PR were monitored for 24 hours. Participants were classified into OSA (AHI ≥ 5) and control (SS) (AHI < 5) groups, and BP and PR were compared. Participants were also divided into groups with and without hypertension, CVDs, or DM to analyze the correlation between AHI, BP, and PR in each group. Results: Mean PRs during the daytime period and during the whole 24-hour period in the OSA group were significantly higher than those in the SS group after controlling for potential confounders. No significant difference was observed in mean BP between the groups. Partial correlation analysis after controlling for confounders showed significant correlation between AHI and PR during daytime and the 24-hour period in participants without hypertension, DM, or CVDs, but not in participants with these conditions. Conclusion: The significant differences and correlations only in PR (not in BP) found in this study suggest that PR could be an early marker for SRBD in individuals without comorbidities, and that an increased sympathetic tone could be responsible for future occurrence of CVD.

Prognostic Implications of Right and Left Atrial Enlargement after Radiofrequency Catheter Ablation in Patients with Nonvalvular Atrial Fibrillation

Moon, Jeonggeun,Lee, Hye-Jeong,Kim, Jong-Youn,Pak, Hui-Nam,Lee, Moon-Hyoung,Kim, Young Jin,Joung, Boyoung The Korean Society of Cardiology 2015 Korean Circulation Journal Vol.45 No.4

<P><B>Background and Objectives</B></P><P>The prognostic role of the right atrium (RA) compared with that of the left atrium (LA) is unclear in patients with atrial fibrillation (AF). We assessed structural changes in both atria and determined their association with recurrence of AF after radiofrequency catheter ablation (RFCA).</P><P><B>Subjects and Methods</B></P><P>All 111 patients with nonvalvular AF (87 men; mean age, 57±11 years; 68 with paroxysmal AF) who underwent RFCA were enrolled consecutively. Three-dimensional volumes of both atria measured from computed tomography images were compared between subjects with and without recurrence of AF during the follow-up.</P><P><B>Results</B></P><P>Early (<3 months), 6-month, and 1-year recurrence was documented in 26 (24%), 30 (27%), and 36 (32%) patients, respectively. Significantly larger RA and LA volume indices (RAVI and LAVI) were observed in the early, 6-month, and 1-year recurrence groups (p<0.05 for all). In multivariate analysis, Early recurrence was independently associated with RAVI (for each 10 mL/m2 increase; odds ratio [OR], 1.31; 95% confidence interval [CI], 1.03-1.66, p= 0.03), but not with LAVI. However, both RAVI and LAVI failed to predict 6-month outcomes independently. LAVI was the only independent predictor of 1-year recurrence (for each 10 mL/m2 increase; OR, 1.36; 95% CI, 1.08-1.71, p=0.009).</P><P><B>Conclusion</B></P><P>RA enlargement was more closely related to early recurrence of AF after RFCA than LA size. However, LA size, rather than RA volume, was a determinant of long-term AF prognosis after RFCA. These findings suggest a temporal pattern in the prognostic implication of enlargement in each atrium that switches over time after RFCA for AF.</P>

키넥트 센서를 이용한 인공표식 기반의 위치결정 시스템

박귀우(Kwiwoo Park),채정근(JeongGeun Chae),문상호(Sang-Ho Moon),박찬식(Chansik Park) 대한전기학회 2014 전기학회논문지 Vol.63 No.1

In this paper, a landmark based localization system using a Kinect sensor is proposed and evaluated with the implemented system for precise and autonomous navigation of low cost robots. The proposed localization method finds the positions of landmark on the image plane and the depth value using color and depth images. The coordinates transforms are defined using the depth value. Using coordinate transformation, the position in the image plane is transformed to the position in the body frame. The ranges between the landmarks and the Kinect sensor are the norm of the landmark positions in body frame. The Kinect sensor position is computed using the tri-lateral whose inputs are the ranges and the known landmark positions. In addition, a new matching method using the pin hole model is proposed to reduce the mismatch between depth and color images. Furthermore, a height error compensation method using the relationship between the body frame and real world coordinates is proposed to reduce the effect of wrong leveling. The error analysis are also given to find out the effect of focal length, principal point and depth value to the range. The experiments using 2D bar code with the implemented system show that the position with less than 3cm error is obtained in enclosed space(3,500mm×3,000mm×2,500mm)

Comparison of inflammatory markers for the prediction of neointimal hyperplasia after drug-eluting stent implantation

Kang, Woong Chol,Il Moon, Chan,Lee, Kyounghoon,Han, Seung Hwan,Suh, Soon Yong,Moon, Jeonggeun,Shin, Mi Seung,Ahn, Taehoon,Shin, Eak Kyun Lippincott Williams Wilkins, Inc. 2011 Coronary artery disease Vol.22 No.8

BACKGROUND: We compared the relationship between inflammatory markers and neointimal hyperplasia (NIH) after drug-eluting stent (DES) implantation. METHODS: We implanted a single DES in 42 consecutive patients with stable angina. The plasma high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6), and matrix metalloproteinase-9 (MMP-9) levels were measured before, and 24 and 72 h after the procedure. Angiography and intravascular ultrasound were performed. RESULTS: No relationship was noted between the baseline hs-CRP level and NIH. A significant positive correlation was noted between NIH and the hs-CRP level obtained at 24 h (r=0.435, P=0.004), and 72 h (r=0.334, P=0.031) after the procedure. Interestingly, there was a positive correlation between the change (&Dgr;) in the hs-CRP level and NIH at 24 h (r=0.414, P=0.006). The fourth quartile of the hs-CRP at 24 h after percutaneous coronary intervention (PCI) had significantly larger volume of NIH than the first quartile (20.1±25.1 vs. 2.7±6.4 mm, P<0.05). Moreover, NIH in the fourth quartile (20.9±26.4 mm) was higher than the first quartile (3.3±8.6 mm) of the &Dgr; hs-CRP level at 24 h (P<0.05) after the procedure. Although the IL-6 level at the baseline and 72 h after the procedure were positively correlated with NIH (r=0.337, P=0.029 and r=0.435, P=0.004, respectively), the &Dgr; IL-6 level at any stage was not correlated with NIH. Neither the MMP-9 level nor the &Dgr; MMP-9 level at any stage was correlated with NIH. CONCLUSION: This prospective intravascular ultrasound study showed the inflammatory response after PCI, as measured by hs-CRP levels, but not the baseline hs-CRP level, predict NIH after DES implantation. Neither a change in the IL-6 nor MMP-9 levels at any stage after PCI reflected NIH.

Leakage Current Reduction Mechanism of Oxide-Nitride-Oxide Inter-Poly Dielectrics through the Post Plasma Oxidation Treatment

Lee, Woong,Jee, Jeonggeun,Yoo, Dae-Han,Lee, Eun-Young,Bok, Jinkwon,Hyung, Younwoo,Kim, Seoksik,Kang, Chang-Jin,Moon, Joo-Tae,Roh, Yonghan IOP Publishing 2011 Japanese journal of applied physics Vol.50 No.4

Complete Versus Culprit-Only Revascularization for ST-Segment Elevation Myocardial Infarction and Multivessel Disease in the 2nd Generation Drug-Eluting Stent Era: Data from the INTERSTELLAR Registry

Sung Woo Kwon,Sang-Don Park,Jeonggeun Moon,Pyung Chun Oh,Ho-Jun Jang,Hyun Woo Park,Tae-Hoon Kim,Kyounghoon Lee,Jon Suh,WoongChol Kang 대한심장학회 2018 Korean Circulation Journal Vol.48 No.11

Background and Objectives: We aimed to compare outcomes of complete revascularization (CR) versus culprit-only revascularization for ST-segment elevation myocardial infarction(STEMI) and multivessel disease (MVD) in the 2nd generation drug-eluting stent (DES) era. Methods: From 2009 to 2014, patients with STEMI and MVD, who underwent primary percutaneous coronary intervention (PCI) using a 2nd generation DES for culprit lesions were enrolled. CR was defined as PCI for a non-infarct-related artery during the index admission. Major adverse cardiovascular event (MACE) was defined as cardiovascular (CV) death, non-fatal myocardial infarction, target lesion revascularization, or heart failure during the follow-up year. Results: In total, 705 MVD patients were suitable for the analysis, of whom 286 (41%) underwent culprit-only PCI and 419 (59%) underwent CR during the index admission. The incidence of MACE was 11.5% in the CR group versus 18.5% in the culprit-only group (hazard ratio [HR], 0.56; 95% confidence interval [CI], 0.37–0.86; p<0.01; adjusted HR, 0.64; 95% CI, 0.40–0.99; p=0.04). The CR group revealed a significantly lower incidence of CV death (7.2% vs. 12.9%; HR, 0.51; 95% CI, 0.31–0.86; p=0.01 and adjusted HR, 0.57; 95% CI; 0.32–0.97; p=0.03, respectively). Conclusions: CR was associated with better outcomes including reductions in MACE and CV death at 1 year of follow-up compared with culprit-only PCI in the 2nd generation DES era.

ANN 기반 도시침수 위험기준 예측 모델 개발 및 학습자료의 확장에 따른 영향 평가

강호선(Kang,Hoseon),조재웅(Cho,Jaewoong),이한승(Lee,Hanseung),황정근(Hwang,Jeonggeun),문혜진(Moon,Hyejin) 한국방재학회 2021 한국방재학회논문집 Vol.21 No.6

도시침수는 단기간 높은 강도의 집중호우에 의해 단시간에 발생하기 때문에 대응을 위해서는 신속하고 정확한 침수 예⋅경보가 필요하다. 선행연구에서 침수피해 통계기반의 도시침수 위험기준 산정 방법을 제시하고 침수 위험기준 예측을 위한 Neuro-Fuzzy 모델을 개발하였다. 최근 인공지능 기술의 발달로 다양한 인공지능 알고리즘의 활용도와 예측 정확성이 향상됨에 따라 도시침수 위험기준 예측에 적용하여 침수 위험기준의 정확성을 향상시키고자 한다. 따라서 본 연구에서는 Artificial Neural Network (ANN) 알고리즘을 이용하여 침수 위험기준을 예측하고;학습자료의 확장 기법 적용을 통한 영향을 분석하였다. ANN 모델의 예측 성능은 RMSE 3.39~9.80 mm;학습자료 확장을 통해 모델 성능은 RMSE 1.08~6.88 mm로 29.8~82.6% 개선되는 것을 확인하였다. Urban flooding occurs during heavy rains of short duration;so quick and accurate warnings of the danger of inundation are required. Previous research proposed methods to estimate statistics-based urban flood alert criteria based on flood damage records and rainfall data;and developed a Neuro-Fuzzy model for predicting appropriate flood alert criteria. A variety of artificial intelligence algorithms have been applied to the prediction of the urban flood alert criteria;and their usage and predictive precision have been enhanced with the recent development of artificial intelligence. Therefore;this study predicted flood alert criteria and analyzed the effect of applying the technique to augmentation training data using the Artificial Neural Network (ANN) algorithm. The predictive performance of the ANN model was RMSE 3.39-9.80 mm;and the model performance with the extension of training data was RMSE 1.08-6.88 mm;indicating that performance was improved by 29.8-82.6%.

S-285 A Propensity Matched Study in Foley Catheter Inserted Patients with Acute Heart Failure

( Jun Soo Lee ),( Youngwoo Jang ),( Woong Chol Kang ),( Jeonggeun Moon ) 대한내과학회 2016 대한내과학회 추계학술대회 Vol.2016 No.1

Background: Overutilization of indwelling urethral catheters (IUCs) in hospitalized patients has been stressed for high rates of urinary complications in previous studies. Risk benefit for such practices have not been evaluated until presently. Design & Method: We retrospectively reviewed a single center tertiary care admission of 329 patients, initially presenting to the ER with acute heart failure(AHF), whom were alert, non-intubated, and over 18 years of age. Propensity scores for IUC insertion were used to assemble pairs of patients with and without IUC insertion to correct imbalances between both groups. Results: Of 329 patients, IUCs were inserted in 200 patients (61%). After propensity score matching, a total of 204 patients (age 72±12, 95 males) with 102 patients in each group, were analyzed. Hospital stay length (13±12 vs. 9±8 days) and urinary complications (15 vs 4%) were significantly higher in the IUC inserted group (p<0.05 for all), while 1 year mortality (HR, 1.114; CI 0.542 - 2.703; p=0.541), stroke (HR, 1.55; CI 0.450 - 6.366; p=0.486), rehospitalization (HR, 1.211; CI 0.412 - 1.639; p=0.578), and major adverse cardiac events (HR, 0.994; CI 0.809 - 1.633; p=0. 436) were not significantly different in both groups. Conclusions: The insertion of IUCs in patients with AHF is associated with prolonged hospital stay length and increased urinary complications, while no one-year outcome benefit is observed.

Routine Indwelling Urethral Catheterization in Acute Heart Failure Patients Is Associated With Increased Urinary Tract Complications Without Improved Heart Failure Outcomes

Jang, Albert Youngwoo,O Brien, Connor,Chung, Wook-Jin,Oh, Pyung Chun,Yu, Jongwook,Lee, Kyounghoon,Kang, Woong Chol,Moon, Jeonggeun UNKNOWN 2018 CIRCULATION JOURNAL Vol.82 No.6

<P>Conclusions: Based on this retrospective analysis, the routine use of IUC may increase length of stay and UTI complications in AHF patients without reducing the risk for major cardiovascular and cerebrovascular events or 30-day rehospitalization rate.</P>