http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Initial Response of Osteoblast-Like Cells on Magnesium Ion Implanted Titanium Surface
( Hyeong Joo Shin ),( Dae Gon Kim ),( Chan Jin Park ),( Lee Ra Cho ),( Hee Su Lee ),( Eung Sun Byon ),( Yong Soo Jeong ) 한국조직공학과 재생의학회 2010 조직공학과 재생의학 Vol.7 No.3
The interactions between the implant surface and surrounding tissue are important for successful osteogenesis. Biomechanical interlocking and biochemical bonding are believed as to be the mechanism of osseointegration involving the initial osteoblast attachment, proliferation and differentiation. The purpose of this study is to evaluate the MC3T3-E1 cell responses to a magnesium (Mg) ion implanted titanium surface produced using a plasma source ion implantation method. Commercially pure titanium discs were prepared to produce four different surfaces; ground surface, Mg-implanted on ground surface, sandblasted surface, and Mg-implanted on sandblasted surface. Cell attachment, proliferation and differentiation of MC3T3-El cells were evaluated. Scanning electron microscopy and confocal laser microscopy revealed more cell proliferation on the Mg ion groups than on the non Mg ion groups. On the ground surface, cells showed some degree of contact guidance in alignment with the grooves. The MTT assay to determine the cellular viability and proliferation showed a higher optical density on the Mg ion groups than on the non Mg ion groups. This suggests that a Mg ion implanted titanium surface induces a better initial cellular response than the non Mg ion groups.
Jung Gon Kim,Sang-Woong Han,Joo Hark Yi,Hyeong Cheon Park,Sang Youb Han 한국영양학회 2020 Nutrition Research and Practice Vol.14 No.1
BACKGROUND/OBJECTIVES: To date, sodium intake has been evaluated based on spot urine instead of 24-hour (hr) urine collection. Nevertheless, the optimal method for assessing daily sodium intake remains unclear. SUBJECTS/METHODS: Fifteen male (age 32.7 ± 6.5 years) participants were offered 3 meals with a total of 9-10 g salt over 24 hours, and 24-hr urine was collected from the second-void urine of the first day to the first-void urine of the second day. Twenty-four-hr urinary sodium (24UNa) was estimated using Tanaka’s equation and the Korean formula, and spot urine Na, potassium (K), chloride (Cl), urea nitrogen (UN), creatinine (Cr), specific gravity (SG) and osmolality (Osm) were measured. The ratios of urinary Na to other parameters were calculated, and correlations with total measured 24UNa were identified. RESULTS: Average 24-hr urine volume was 1,403 ± 475 mL, and measured 24UNa was 143.9 ± 42.1 mEq (range, 87.1-239.4 mEq). Measured 24UNa was significantly correlated with urinary Na/UN (r = 0.560, P < 0.01), urinary Na/Osm (r = 0.510, P < 0.01), urinary Na/Cr (r = 0.392, P < 0.01), urinary Na/K (r = 0.290, P < 0.01), 24UNa estimated using Tanaka’s equation (r = 0.452, P < 0.01) and the Korean formula (r = 0.414, P < 0.01), age (r = 0.548, P < 0.01), weight (r = 0.497, P < 0.01), and height (r = 0.393, P < 0.01) in all spot urine samples. Estimated 24UNa based on the second-void spot urine of the first day tended to be more closely correlated with measured 24UNa than were estimates from the other spot urine samples. The significant parameters correlated with the second-void urine of the first day were urinary Na/K (r = 0.647, P < 0.01), urinary Na/Cr (r = 0.558, P < 0.05), and estimated 24UNa using Tanaka’s equation (r = 0.616, P < 0.05) and the Korean formula (r = 0.588, P < 0.05). CONCLUSIONS: Second-void urine is more reliable than first-void urine for estimating 24UNa. Urinary Na/K in the second-void urine on the first day is significantly correlated with 24UNa. Further studies are needed to establish the most reliable index and the optimal time of urine sampling for predicting 24UNa.
경피적 심낭배액술과 Trastuzumab 단독요법으로 치료한 심낭압전을 동반한 유방암의 심막전이
문형곤(Hyeong-Gon Moon),정은정(Eun-Jung Jung),박순태(Soon-Tae Park),송대현(Dae Hyun Song),하우송(Woo-Song Ha),최상경(Sang-Kyung Choi),홍순찬(Soon-Chan Hong),이영준(Young-Joon Lee),주영태(Young-Tae Joo),정치영(Chi-Young Jeong) 대한외과학회 2008 Annals of Surgical Treatment and Research(ASRT) Vol.75 No.2
Although autopsy studies suggest that malignant pericardial effusion is present in up to 15% of the patients suffering with malignancies, symptomatic pericardial effusion presenting as a first manifestation of systemic recurrence in a breast cancer patient is a rare condition. Symptomatic malignant pericardial effusion requires prompt attention and intervention since it can lead to the cardiac tamponade. Treatment of symptomatic pericardial effusion includes pericardial decompression and systemic or intrapericardial chemotherapy. We recently experienced a patient with early breast cancer who developed cardiac tamponade from malignant pericardial effusion as a first manifestation of systemic recurrence 4 years after her initial surgery. The patient was treated with percutaneous pericardiocentesis and she subsequently received systemic trastuzumab. After 6 cycles of trastuzumab, the follow-up CT showed complete disappearance of the pericardial effusion and the mediastinal lymph nodes.
Shin, Joo Young,Yu, Hyeong Gon Lippincott 2012 Retina Vol.32 No.3
PURPOSE:: To identify spectral-domain optical coherence tomography findings related to visual outcome in myopic foveoschisis after 25-gauge transconjunctival sutureless vitrectomy. METHODS:: Thirty-eight eyes with myopic foveoschisis were prospectively followed-up to 6 months after vitrectomy. Best-corrected visual acuity (BCVA), axial length, and spectral-domain optical coherence tomography findings were analyzed for identification of factors affecting visual outcome. RESULTS:: Best-corrected visual acuity improved significantly (preoperative 0.841 ± 0.534 logarithm of minimal angle of resolution to postoperative 0.532 ± 0.536 logarithm of minimal angle of resolution, P = 0.001), and central retinal thickness showed significant reduction (preoperative 409 ± 143 μm to postoperative 259 ± 72 μm, P < 0.001) with surgery. Anatomical success was achieved in 34/38 eyes (89.5%). Photoreceptor layer disruption was found in 20 of 38 eyes (52.6%) preoperatively and persisted after surgery in 18 of 20 eyes (90.0%). Patients with preoperative photoreceptor layer defects had significantly more associated foveal detachments and irregular choroidal surfaces and worse preoperative and final best-corrected visual acuity. Preoperative best-corrected visual acuity showed significant correlation with final best-corrected visual acuity (Pearson correlation coefficient = 0.555, P = 0.001). Patients with irregular choroidal surfaces and photoreceptor layer disruption had significantly worse final best-corrected visual acuity (P = 0.035, 0.005). CONCLUSION:: Twenty-five-gauge transconjunctival sutureless vitrectomy showed favorable results for the management of myopic foveoschisis. Photoreceptor layer defects and irregular choroidal surfaces on spectral-domain optical coherence tomography persist despite surgery, limiting visual outcome.
공막돌륭술 후 재발된 열공성 망막박리에서 유리체절제술의 효과
오주연(Joo Youn Oh),유형곤(Hyeong Gon Yu) 대한검안학회 2007 Annals of optometry and contact lens Vol.6 No.1
목적: 열공성 망막박리에서 공막돌륭술로 망막이 유착되었다가 재발된 경우 유리체절제술의 효과를 알아보고자 하였다. 대상과 방법: 열공성 망막박리로 공막돌륭술을 시행하고 망막이 6주 이상 재유착되었다가 재발된 환자에서 유리체절제술을 시행한 경우 그 임상결과를 분석하였다. 결과: 246명 중 망막박리가 재발되어 유리체절제술을 시행받은 경우는 31명(12.6%)이었다. 수술 전에 황반부를 침범한 경우가 31안 중 23안(74.2%)이었고 증식유리체망막병증은 11안(35.5%)에서 동반되어 있었다. 가스충전은 21안(67.7%)에서 하였고, 10안(32.3%)에서 실리콘오일을 주입하였다. 초음파 유화술과 인공수정체삽입이 5안에서, 수정체절제술이 4안에서 동시에 시행되었다. 유리체절제술 후 6안에서 망막박리가 재발하여 5안에서 이차 유리체절제술로써 망막이 재유착되어 최종 검사상 30안(96.8%)에서 해부학적인 성공을 나타내었다. Snellen 시력 0.1 이상의 기능적 성공은 19안(61.3%)에서만 나타났다. 결론: 단순 열공성 망막박리 환자에서 성공적인 공막돌륭술 후에도 정기적인 추적관찰이 필요하며 재발하였을 경우 유리체절제술이 유용한 치료방법이 될 수 있다. Purpose: To evaluate the surgical outcome of pars plana vitrectomy for the treatment of the recurrent rhegmatogenous retinal detachment more than 6 weeks after reattachment with primary scleral buckling procedures. Methods: We reviewed the clinical and operative records of 31 eyes of 31 patients who underwent pars plana vitrectomy for the treatment of the recurrent retinal detachment more than 6 weeks after reattachment with primary scleral buckling procedures. Anatomical and functional outcomes were analyzed. Results: Of total 246 patients who had achieved a retinal reattachment after scleral buckling, redetachment occurred in 31 patients from 6 weeks to 36 months (average, 10.1 months). Macula was involved in 23 of 31 patients (74.2%) and proliferative vitreoretinopathy was combined in 11 eyes (35.5%). Gas injection was done in 21 eyes (67.7%), and silicone oil was injected in 10 eyes (32.3%), intraoperatively. hacoemulsification and intraocular lens implantation in 5 eyes and lensectomy in 4 eyes were performed simultaneously with pars plana vitrectomy. Retina was redetached in 6 patients, of which 5 patients had a second vitrectomy. Overall, 30 patients (96.8%) achieved an anatomic success, while only 19 eyes (61.3%) achieved a visual acuity of better than 0.1 in Snellen chart. Conclusions: Regular follow-up is necessary for the patients with rhegmatogenous retinal detachment, even after successful scleral buckling, and pars plana vitrectomy can be useful for recurrent retinal detachment in these patients.